int-snw-3068

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.938	1.28e-15	2.33e-03	3.84e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-3068 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ HDGF ]	3068	1	0.058	0.938	112	-	-
RPS11	6205	36	0.993	1.113	175	Yes	-
NACA	4666	2	0.996	0.968	45	Yes	-
EFTUD2	9343	7	0.883	0.969	78	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
FBL	2091	7	0.839	1.151	65	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	FBL	2091	pp	--	int.I2D: MINT
FBL	2091	HDGF	3068	pp	--	int.Intact: MI:0914(association)
HDGF	3068	EFTUD2	9343	pp	--	int.Intact: MI:0914(association)
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
HDGF	3068	RPS11	6205	pp	--	int.Intact: MI:0914(association)
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
HDGF	3068	NACA	4666	pp	--	int.Intact: MI:0914(association)

Related GO terms (122)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0044267	cellular protein metabolic process	1.94e-06	2.79e-02	4.249	5	29	474
GO:0044822	poly(A) RNA binding	3.74e-06	5.40e-02	3.357	6	49	1056
GO:0006412	translation	4.19e-06	6.05e-02	4.971	4	20	230
GO:0019083	viral transcription	9.36e-06	1.35e-01	6.061	3	10	81
GO:0006415	translational termination	1.16e-05	1.68e-01	5.958	3	10	87
GO:0006414	translational elongation	1.42e-05	2.05e-01	5.862	3	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.99e-05	2.87e-01	5.701	3	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.62e-05	3.77e-01	5.568	3	11	114
GO:0019058	viral life cycle	2.69e-05	3.87e-01	5.556	3	13	115
GO:0006413	translational initiation	3.97e-05	5.72e-01	5.368	3	17	131
GO:0003735	structural constituent of ribosome	4.53e-05	6.54e-01	5.303	3	10	137
GO:0016020	membrane	5.65e-05	8.14e-01	2.686	6	90	1681
GO:0016032	viral process	1.15e-04	1.00e+00	3.755	4	55	534
GO:0016071	mRNA metabolic process	1.93e-04	1.00e+00	4.600	3	31	223
GO:0022627	cytosolic small ribosomal subunit	1.97e-04	1.00e+00	6.531	2	4	39
GO:0015030	Cajal body	2.52e-04	1.00e+00	6.357	2	3	44
GO:0016070	RNA metabolic process	2.61e-04	1.00e+00	4.453	3	32	247
GO:0010467	gene expression	2.77e-04	1.00e+00	3.430	4	59	669
GO:0070062	extracellular vesicular exosome	4.35e-04	1.00e+00	2.172	6	104	2400
GO:1990259	histone-glutamine methyltransferase activity	5.55e-04	1.00e+00	10.816	1	1	1
GO:1990258	histone glutamine methylation	5.55e-04	1.00e+00	10.816	1	1	1
GO:1901227	negative regulation of transcription from RNA polymerase II promoter involved in heart development	5.55e-04	1.00e+00	10.816	1	1	1
GO:0005854	nascent polypeptide-associated complex	5.55e-04	1.00e+00	10.816	1	1	1
GO:0016074	snoRNA metabolic process	5.55e-04	1.00e+00	10.816	1	1	1
GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in heart development	5.55e-04	1.00e+00	10.816	1	1	1
GO:0001649	osteoblast differentiation	1.10e-03	1.00e+00	5.293	2	6	92
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.11e-03	1.00e+00	9.816	1	1	2
GO:0005055	laminin receptor activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006407	rRNA export from nucleus	1.11e-03	1.00e+00	9.816	1	1	2
GO:0048633	positive regulation of skeletal muscle tissue growth	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006364	rRNA processing	1.15e-03	1.00e+00	5.261	2	6	94
GO:0061384	heart trabecula morphogenesis	1.66e-03	1.00e+00	9.231	1	1	3
GO:0003231	cardiac ventricle development	1.66e-03	1.00e+00	9.231	1	1	3
GO:0001652	granular component	2.22e-03	1.00e+00	8.816	1	1	4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.22e-03	1.00e+00	8.816	1	1	4
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	2.22e-03	1.00e+00	8.816	1	1	4
GO:0030686	90S preribosome	2.22e-03	1.00e+00	8.816	1	1	4
GO:0010664	negative regulation of striated muscle cell apoptotic process	2.22e-03	1.00e+00	8.816	1	1	4
GO:0031428	box C/D snoRNP complex	2.22e-03	1.00e+00	8.816	1	1	4
GO:0048742	regulation of skeletal muscle fiber development	2.77e-03	1.00e+00	8.494	1	1	5
GO:0030957	Tat protein binding	3.32e-03	1.00e+00	8.231	1	3	6
GO:0001222	transcription corepressor binding	3.88e-03	1.00e+00	8.009	1	1	7
GO:0000028	ribosomal small subunit assembly	3.88e-03	1.00e+00	8.009	1	1	7
GO:0070688	MLL5-L complex	4.43e-03	1.00e+00	7.816	1	1	8
GO:0005737	cytoplasm	5.35e-03	1.00e+00	1.522	6	110	3767
GO:0043403	skeletal muscle tissue regeneration	6.09e-03	1.00e+00	7.357	1	2	11
GO:0042273	ribosomal large subunit biogenesis	7.19e-03	1.00e+00	7.116	1	4	13
GO:0035267	NuA4 histone acetyltransferase complex	7.74e-03	1.00e+00	7.009	1	4	14
GO:0050998	nitric-oxide synthase binding	8.84e-03	1.00e+00	6.816	1	1	16
GO:0017025	TBP-class protein binding	9.39e-03	1.00e+00	6.729	1	3	17
GO:0005515	protein binding	1.12e-02	1.00e+00	1.067	7	184	6024
GO:0001106	RNA polymerase II transcription corepressor activity	1.16e-02	1.00e+00	6.424	1	1	21
GO:0030863	cortical cytoskeleton	1.21e-02	1.00e+00	6.357	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.357	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.27e-02	1.00e+00	6.293	1	4	23
GO:0043236	laminin binding	1.27e-02	1.00e+00	6.293	1	1	23
GO:0003723	RNA binding	1.43e-02	1.00e+00	3.398	2	20	342
GO:0031492	nucleosomal DNA binding	1.49e-02	1.00e+00	6.061	1	4	27
GO:0019843	rRNA binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0043022	ribosome binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0019894	kinesin binding	1.54e-02	1.00e+00	6.009	1	1	28
GO:0005925	focal adhesion	1.63e-02	1.00e+00	3.300	2	19	366
GO:0005654	nucleoplasm	1.77e-02	1.00e+00	2.322	3	76	1082
GO:0001895	retina homeostasis	1.87e-02	1.00e+00	5.729	1	1	34
GO:0008033	tRNA processing	1.87e-02	1.00e+00	5.729	1	1	34
GO:0034332	adherens junction organization	1.98e-02	1.00e+00	5.646	1	1	36
GO:0051084	'de novo' posttranslational protein folding	2.03e-02	1.00e+00	5.607	1	4	37
GO:0070527	platelet aggregation	2.09e-02	1.00e+00	5.568	1	2	38
GO:0021762	substantia nigra development	2.42e-02	1.00e+00	5.357	1	2	44
GO:0022625	cytosolic large ribosomal subunit	2.69e-02	1.00e+00	5.201	1	6	49
GO:0017053	transcriptional repressor complex	2.79e-02	1.00e+00	5.144	1	2	51
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.90e-02	1.00e+00	5.088	1	5	53
GO:0045216	cell-cell junction organization	2.96e-02	1.00e+00	5.061	1	2	54
GO:0005840	ribosome	3.17e-02	1.00e+00	4.958	1	1	58
GO:0006987	activation of signaling protein activity involved in unfolded protein response	3.33e-02	1.00e+00	4.885	1	3	61
GO:0005829	cytosol	3.48e-02	1.00e+00	1.531	4	132	2496
GO:0034329	cell junction assembly	3.71e-02	1.00e+00	4.729	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.03e-02	1.00e+00	4.607	1	6	74
GO:0071013	catalytic step 2 spliceosome	4.25e-02	1.00e+00	4.531	1	4	78
GO:0030968	endoplasmic reticulum unfolded protein response	4.30e-02	1.00e+00	4.512	1	4	79
GO:0005681	spliceosomal complex	4.51e-02	1.00e+00	4.441	1	4	83
GO:0005200	structural constituent of cytoskeleton	4.94e-02	1.00e+00	4.308	1	8	91
GO:0006928	cellular component movement	4.94e-02	1.00e+00	4.308	1	7	91
GO:0005730	nucleolus	5.31e-02	1.00e+00	1.721	3	69	1641
GO:0014069	postsynaptic density	5.68e-02	1.00e+00	4.102	1	3	105
GO:0072562	blood microparticle	5.99e-02	1.00e+00	4.022	1	3	111
GO:0030529	ribonucleoprotein complex	6.05e-02	1.00e+00	4.009	1	8	112
GO:0006325	chromatin organization	6.36e-02	1.00e+00	3.933	1	5	118
GO:0008201	heparin binding	6.57e-02	1.00e+00	3.885	1	4	122
GO:0000790	nuclear chromatin	6.94e-02	1.00e+00	3.805	1	9	129
GO:0005634	nucleus	7.14e-02	1.00e+00	0.984	5	136	4559
GO:0008083	growth factor activity	7.56e-02	1.00e+00	3.677	1	1	141
GO:0006457	protein folding	7.66e-02	1.00e+00	3.656	1	7	143
GO:0061024	membrane organization	7.77e-02	1.00e+00	3.636	1	7	145
GO:0006397	mRNA processing	8.54e-02	1.00e+00	3.494	1	2	160
GO:0000398	mRNA splicing, via spliceosome	8.74e-02	1.00e+00	3.459	1	8	164
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.80e-02	1.00e+00	3.450	1	7	165
GO:0030424	axon	8.85e-02	1.00e+00	3.441	1	4	166
GO:0016607	nuclear speck	9.15e-02	1.00e+00	3.390	1	3	172
GO:0005615	extracellular space	9.43e-02	1.00e+00	1.914	2	17	957
GO:0003924	GTPase activity	1.04e-01	1.00e+00	3.194	1	12	197
GO:0006184	GTP catabolic process	1.13e-01	1.00e+00	3.075	1	12	214
GO:0008380	RNA splicing	1.20e-01	1.00e+00	2.983	1	11	228
GO:0003713	transcription coactivator activity	1.24e-01	1.00e+00	2.927	1	10	237
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.799	1	5	259
GO:0003677	DNA binding	1.42e-01	1.00e+00	1.566	2	28	1218
GO:0005856	cytoskeleton	1.50e-01	1.00e+00	2.631	1	12	291
GO:0043234	protein complex	1.52e-01	1.00e+00	2.612	1	18	295
GO:0005525	GTP binding	1.60e-01	1.00e+00	2.540	1	12	310
GO:0019901	protein kinase binding	1.63e-01	1.00e+00	2.508	1	21	317
GO:0007411	axon guidance	1.64e-01	1.00e+00	2.499	1	13	319
GO:0008283	cell proliferation	1.68e-01	1.00e+00	2.459	1	14	328
GO:0015031	protein transport	1.74e-01	1.00e+00	2.402	1	5	341
GO:0007155	cell adhesion	1.87e-01	1.00e+00	2.289	1	6	369
GO:0006351	transcription, DNA-templated	1.88e-01	1.00e+00	1.318	2	31	1446
GO:0007596	blood coagulation	2.26e-01	1.00e+00	1.986	1	18	455
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.76e-01	1.00e+00	1.661	1	16	570
GO:0045087	innate immune response	2.87e-01	1.00e+00	1.597	1	24	596
GO:0007165	signal transduction	4.05e-01	1.00e+00	0.991	1	24	907
GO:0006355	regulation of transcription, DNA-templated	4.36e-01	1.00e+00	0.855	1	18	997
GO:0005524	ATP binding	5.30e-01	1.00e+00	0.474	1	60	1298
GO:0005886	plasma membrane	7.94e-01	1.00e+00	-0.518	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-3068

Statistics

Genes (8)

Interactions (8)

Related GO terms (122)