int-snw-1537

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.967	9.19e-17	1.22e-03	2.39e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-1537 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACTB	60	167	1.153	1.151	587	Yes	-
[ CYC1 ]	1537	1	0.440	0.967	72	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-
PIGK	10026	5	0.718	0.992	68	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
CYC1	1537	PIGK	10026	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow
CYC1	1537	HSPD1	3329	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
CYC1	1537	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (137)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016020	membrane	2.49e-06	3.59e-02	3.101	6	90	1681
GO:0044267	cellular protein metabolic process	1.64e-05	2.36e-01	4.342	4	29	474
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	4.16e-04	1.00e+00	11.231	1	1	1
GO:0048291	isotype switching to IgG isotypes	4.16e-04	1.00e+00	11.231	1	1	1
GO:0002368	B cell cytokine production	4.16e-04	1.00e+00	11.231	1	1	1
GO:0019083	viral transcription	4.61e-04	1.00e+00	5.891	2	10	81
GO:0006415	translational termination	5.31e-04	1.00e+00	5.788	2	10	87
GO:0006414	translational elongation	6.07e-04	1.00e+00	5.692	2	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.58e-04	1.00e+00	5.531	2	10	104
GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.32e-04	1.00e+00	10.231	1	1	2
GO:0005055	laminin receptor activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0006407	rRNA export from nucleus	8.32e-04	1.00e+00	10.231	1	1	2
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	9.10e-04	1.00e+00	5.398	2	11	114
GO:0019058	viral life cycle	9.26e-04	1.00e+00	5.386	2	13	115
GO:0016032	viral process	9.28e-04	1.00e+00	3.755	3	55	534
GO:0006413	translational initiation	1.20e-03	1.00e+00	5.198	2	17	131
GO:0006458	'de novo' protein folding	1.25e-03	1.00e+00	9.646	1	1	3
GO:0030135	coated vesicle	1.25e-03	1.00e+00	9.646	1	1	3
GO:0003735	structural constituent of ribosome	1.31e-03	1.00e+00	5.133	2	10	137
GO:0006457	protein folding	1.43e-03	1.00e+00	5.071	2	7	143
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.66e-03	1.00e+00	9.231	1	1	4
GO:0030686	90S preribosome	1.66e-03	1.00e+00	9.231	1	1	4
GO:0070469	respiratory chain	2.08e-03	1.00e+00	8.909	1	1	5
GO:0046696	lipopolysaccharide receptor complex	2.08e-03	1.00e+00	8.909	1	1	5
GO:0003923	GPI-anchor transamidase activity	2.08e-03	1.00e+00	8.909	1	1	5
GO:0042765	GPI-anchor transamidase complex	2.08e-03	1.00e+00	8.909	1	1	5
GO:0003688	DNA replication origin binding	2.49e-03	1.00e+00	8.646	1	2	6
GO:0030957	Tat protein binding	2.49e-03	1.00e+00	8.646	1	3	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	2.49e-03	1.00e+00	8.646	1	1	6
GO:0016255	attachment of GPI anchor to protein	2.91e-03	1.00e+00	8.424	1	1	7
GO:0000028	ribosomal small subunit assembly	2.91e-03	1.00e+00	8.424	1	1	7
GO:0034235	GPI anchor binding	2.91e-03	1.00e+00	8.424	1	1	7
GO:0070688	MLL5-L complex	3.32e-03	1.00e+00	8.231	1	1	8
GO:0051604	protein maturation	3.32e-03	1.00e+00	8.231	1	1	8
GO:0016071	mRNA metabolic process	3.43e-03	1.00e+00	4.430	2	31	223
GO:0006412	translation	3.64e-03	1.00e+00	4.386	2	20	230
GO:0043032	positive regulation of macrophage activation	4.15e-03	1.00e+00	7.909	1	1	10
GO:0016070	RNA metabolic process	4.19e-03	1.00e+00	4.283	2	32	247
GO:0032727	positive regulation of interferon-alpha production	4.57e-03	1.00e+00	7.772	1	1	11
GO:0033762	response to glucagon	4.57e-03	1.00e+00	7.772	1	1	11
GO:0005743	mitochondrial inner membrane	5.24e-03	1.00e+00	4.117	2	8	277
GO:0042273	ribosomal large subunit biogenesis	5.40e-03	1.00e+00	7.531	1	4	13
GO:0001530	lipopolysaccharide binding	5.40e-03	1.00e+00	7.531	1	3	13
GO:0051131	chaperone-mediated protein complex assembly	5.40e-03	1.00e+00	7.531	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	5.81e-03	1.00e+00	7.424	1	4	14
GO:0043234	protein complex	5.92e-03	1.00e+00	4.027	2	18	295
GO:0042026	protein refolding	6.22e-03	1.00e+00	7.324	1	2	15
GO:0044822	poly(A) RNA binding	6.62e-03	1.00e+00	2.772	3	49	1056
GO:0050998	nitric-oxide synthase binding	6.64e-03	1.00e+00	7.231	1	1	16
GO:0050870	positive regulation of T cell activation	7.05e-03	1.00e+00	7.144	1	1	17
GO:0032733	positive regulation of interleukin-10 production	7.88e-03	1.00e+00	6.983	1	1	19
GO:0070062	extracellular vesicular exosome	8.64e-03	1.00e+00	2.002	4	104	2400
GO:0042100	B cell proliferation	8.71e-03	1.00e+00	6.839	1	1	21
GO:0003756	protein disulfide isomerase activity	9.12e-03	1.00e+00	6.772	1	1	22
GO:0030863	cortical cytoskeleton	9.12e-03	1.00e+00	6.772	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	9.12e-03	1.00e+00	6.772	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	9.53e-03	1.00e+00	6.708	1	4	23
GO:0043236	laminin binding	9.53e-03	1.00e+00	6.708	1	1	23
GO:0005829	cytosol	9.98e-03	1.00e+00	1.946	4	132	2496
GO:0042113	B cell activation	1.04e-02	1.00e+00	6.587	1	2	25
GO:0032735	positive regulation of interleukin-12 production	1.04e-02	1.00e+00	6.587	1	1	25
GO:0006501	C-terminal protein lipidation	1.08e-02	1.00e+00	6.531	1	2	26
GO:0043022	ribosome binding	1.12e-02	1.00e+00	6.476	1	3	27
GO:0031492	nucleosomal DNA binding	1.12e-02	1.00e+00	6.476	1	4	27
GO:0019894	kinesin binding	1.16e-02	1.00e+00	6.424	1	1	28
GO:0001895	retina homeostasis	1.41e-02	1.00e+00	6.144	1	1	34
GO:0034332	adherens junction organization	1.49e-02	1.00e+00	6.061	1	1	36
GO:0032755	positive regulation of interleukin-6 production	1.49e-02	1.00e+00	6.061	1	2	36
GO:0051084	'de novo' posttranslational protein folding	1.53e-02	1.00e+00	6.022	1	4	37
GO:0070527	platelet aggregation	1.57e-02	1.00e+00	5.983	1	2	38
GO:0032729	positive regulation of interferon-gamma production	1.61e-02	1.00e+00	5.946	1	2	39
GO:0022627	cytosolic small ribosomal subunit	1.61e-02	1.00e+00	5.946	1	4	39
GO:0042110	T cell activation	1.73e-02	1.00e+00	5.839	1	3	42
GO:0021762	substantia nigra development	1.82e-02	1.00e+00	5.772	1	2	44
GO:0022625	cytosolic large ribosomal subunit	2.02e-02	1.00e+00	5.616	1	6	49
GO:0004197	cysteine-type endopeptidase activity	2.06e-02	1.00e+00	5.587	1	3	50
GO:0006986	response to unfolded protein	2.06e-02	1.00e+00	5.587	1	2	50
GO:0005905	coated pit	2.06e-02	1.00e+00	5.587	1	3	50
GO:0003725	double-stranded RNA binding	2.14e-02	1.00e+00	5.531	1	5	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.19e-02	1.00e+00	5.503	1	5	53
GO:0030176	integral component of endoplasmic reticulum membrane	2.19e-02	1.00e+00	5.503	1	2	53
GO:0045216	cell-cell junction organization	2.23e-02	1.00e+00	5.476	1	2	54
GO:0002039	p53 binding	2.27e-02	1.00e+00	5.450	1	7	55
GO:0051087	chaperone binding	2.43e-02	1.00e+00	5.348	1	6	59
GO:0030141	secretory granule	2.55e-02	1.00e+00	5.277	1	2	62
GO:0034329	cell junction assembly	2.80e-02	1.00e+00	5.144	1	1	68
GO:0003697	single-stranded DNA binding	2.80e-02	1.00e+00	5.144	1	5	68
GO:0010467	gene expression	2.85e-02	1.00e+00	2.845	2	59	669
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.04e-02	1.00e+00	5.022	1	6	74
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	3.16e-02	1.00e+00	4.964	1	7	77
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3.28e-02	1.00e+00	4.909	1	3	80
GO:0022904	respiratory electron transport chain	3.48e-02	1.00e+00	4.822	1	1	85
GO:0050821	protein stabilization	3.61e-02	1.00e+00	4.772	1	2	88
GO:0006928	cellular component movement	3.73e-02	1.00e+00	4.723	1	7	91
GO:0005200	structural constituent of cytoskeleton	3.73e-02	1.00e+00	4.723	1	8	91
GO:0051082	unfolded protein binding	3.81e-02	1.00e+00	4.692	1	5	93
GO:0020037	heme binding	3.81e-02	1.00e+00	4.692	1	2	93
GO:0006364	rRNA processing	3.85e-02	1.00e+00	4.677	1	6	94
GO:0014069	postsynaptic density	4.29e-02	1.00e+00	4.517	1	3	105
GO:0005506	iron ion binding	4.29e-02	1.00e+00	4.517	1	4	105
GO:0005737	cytoplasm	4.38e-02	1.00e+00	1.352	4	110	3767
GO:0072562	blood microparticle	4.53e-02	1.00e+00	4.437	1	3	111
GO:0030529	ribonucleoprotein complex	4.57e-02	1.00e+00	4.424	1	8	112
GO:0044237	cellular metabolic process	4.77e-02	1.00e+00	4.361	1	5	117
GO:0006325	chromatin organization	4.81e-02	1.00e+00	4.348	1	5	118
GO:0005515	protein binding	4.97e-02	1.00e+00	0.997	5	184	6024
GO:0000790	nuclear chromatin	5.25e-02	1.00e+00	4.220	1	9	129
GO:0005615	extracellular space	5.52e-02	1.00e+00	2.329	2	17	957
GO:0016887	ATPase activity	5.69e-02	1.00e+00	4.102	1	7	140
GO:0061024	membrane organization	5.88e-02	1.00e+00	4.051	1	7	145
GO:0005739	mitochondrion	5.95e-02	1.00e+00	2.268	2	28	998
GO:0005769	early endosome	6.16e-02	1.00e+00	3.983	1	2	152
GO:0043687	post-translational protein modification	6.55e-02	1.00e+00	3.891	1	5	162
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	6.67e-02	1.00e+00	3.865	1	7	165
GO:0030424	axon	6.71e-02	1.00e+00	3.856	1	4	166
GO:0005759	mitochondrial matrix	9.12e-02	1.00e+00	3.398	1	14	228
GO:0005524	ATP binding	9.51e-02	1.00e+00	1.889	2	60	1298
GO:0043065	positive regulation of apoptotic process	1.06e-01	1.00e+00	3.165	1	10	268
GO:0005856	cytoskeleton	1.15e-01	1.00e+00	3.046	1	12	291
GO:0006200	ATP catabolic process	1.16e-01	1.00e+00	3.041	1	15	292
GO:0019901	protein kinase binding	1.25e-01	1.00e+00	2.923	1	21	317
GO:0007411	axon guidance	1.26e-01	1.00e+00	2.914	1	13	319
GO:0003723	RNA binding	1.34e-01	1.00e+00	2.813	1	20	342
GO:0005925	focal adhesion	1.43e-01	1.00e+00	2.715	1	19	366
GO:0007155	cell adhesion	1.44e-01	1.00e+00	2.704	1	6	369
GO:0006508	proteolysis	1.47e-01	1.00e+00	2.669	1	9	378
GO:0009986	cell surface	1.56e-01	1.00e+00	2.580	1	11	402
GO:0043066	negative regulation of apoptotic process	1.64e-01	1.00e+00	2.503	1	31	424
GO:0007596	blood coagulation	1.75e-01	1.00e+00	2.401	1	18	455
GO:0005789	endoplasmic reticulum membrane	2.15e-01	1.00e+00	2.076	1	16	570
GO:0045087	innate immune response	2.24e-01	1.00e+00	2.012	1	24	596
GO:0005886	plasma membrane	2.93e-01	1.00e+00	0.897	2	45	2582
GO:0005654	nucleoplasm	3.74e-01	1.00e+00	1.152	1	76	1082
GO:0044281	small molecule metabolic process	4.09e-01	1.00e+00	0.989	1	58	1211
GO:0016021	integral component of membrane	5.88e-01	1.00e+00	0.278	1	27	1982
GO:0005634	nucleus	6.14e-01	1.00e+00	0.077	2	136	4559

Wolf-ratios-Mammosphere-Adherent

int-snw-1537

Statistics

Genes (6)

Interactions (6)

Related GO terms (137)