Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
int-snw-1029 | chia-screen-data-Fav | 2.959 | 7.22e-17 | 1.01e-04 | 1.12e-03 | 11 | 10 |
reg-snw-80153 | chia-screen-data-Fav | 2.203 | 2.78e-07 | 4.60e-02 | 3.49e-02 | 32 | 22 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
CNOT1 | 23019 | 7 | -2.347 | 2.263 | 124 | Yes | - |
CHERP | 10523 | 2 | -1.632 | 2.203 | 210 | - | - |
RAE1 | 8480 | 2 | -1.501 | 2.342 | 204 | - | - |
PHB | 5245 | 12 | -2.743 | 2.689 | 163 | Yes | Yes |
RASSF7 | 8045 | 2 | -1.518 | 2.203 | 49 | - | - |
VARS | 7407 | 8 | -2.366 | 2.689 | 204 | Yes | - |
POU5F1 | 5460 | 12 | -5.148 | 3.538 | 179 | Yes | Yes |
FBXO22 | 26263 | 8 | -1.739 | 2.459 | 208 | - | - |
EDC3 | 80153 | 2 | -0.943 | 2.203 | 42 | - | - |
E4F1 | 1877 | 3 | -2.370 | 2.959 | 27 | Yes | Yes |
RNF40 | 9810 | 2 | -2.082 | 2.492 | 63 | Yes | - |
EIF2S2 | 8894 | 9 | -2.999 | 2.459 | 103 | Yes | Yes |
FBXL6 | 26233 | 5 | -2.253 | 2.689 | 22 | Yes | - |
SUV39H2 | 79723 | 7 | -2.307 | 2.410 | 21 | Yes | Yes |
BEST1 | 7439 | 2 | -2.250 | 2.281 | 19 | Yes | - |
KLC3 | 147700 | 2 | -2.130 | 2.290 | 132 | Yes | - |
ETF1 | 2107 | 7 | -2.829 | 2.503 | 77 | Yes | Yes |
CCT7 | 10574 | 10 | -2.335 | 2.459 | 173 | Yes | - |
CPSF3 | 51692 | 7 | -2.686 | 2.503 | 31 | Yes | Yes |
HNRNPU | 3192 | 12 | -2.869 | 2.644 | 172 | Yes | - |
DRG2 | 1819 | 2 | -2.526 | 2.492 | 11 | Yes | - |
GTF3C2 | 2976 | 2 | -1.230 | 2.225 | 179 | - | - |
NDUFA4L2 | 56901 | 10 | -2.477 | 2.459 | 21 | Yes | - |
NONO | 4841 | 2 | -1.232 | 2.203 | 223 | - | - |
TMEM68 | 137695 | 2 | -1.565 | 2.312 | 97 | - | - |
WDR18 | 57418 | 2 | -1.321 | 2.225 | 213 | - | - |
YAP1 | 10413 | 12 | -4.256 | 3.538 | 53 | Yes | - |
NCBP1 | 4686 | 8 | -2.510 | 2.459 | 84 | Yes | Yes |
SYNCRIP | 10492 | 8 | -2.401 | 2.503 | 247 | Yes | Yes |
FTSJ1 | 24140 | 5 | -2.463 | 2.689 | 130 | Yes | Yes |
LCE1E | 353135 | 2 | -2.428 | 2.414 | 31 | Yes | Yes |
GSPT1 | 2935 | 7 | -2.313 | 2.503 | 47 | Yes | Yes |
NFRKB | 4798 | 3 | -3.129 | 3.108 | 33 | Yes | Yes |
YY1 | 7528 | 3 | -2.572 | 3.120 | 168 | Yes | Yes |
GPS1 | 2873 | 10 | -3.621 | 2.689 | 62 | Yes | Yes |
NOLC1 | 9221 | 5 | -1.985 | 2.503 | 136 | - | - |
POLH | 5429 | 8 | -2.586 | 2.459 | 24 | Yes | Yes |
DDIT3 | 1649 | 11 | -2.825 | 3.504 | 343 | Yes | Yes |
CDKN2A | 1029 | 3 | -1.774 | 2.959 | 126 | - | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
RAE1 | 8480 | FBXL6 | 26233 | pd | > | reg.ITFP.txt: no annot |
ETF1 | 2107 | SYNCRIP | 10492 | pd | < | reg.ITFP.txt: no annot |
NCBP1 | 4686 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
PHB | 5245 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
CHERP | 10523 | KLC3 | 147700 | pd | <> | reg.ITFP.txt: no annot |
GPS1 | 2873 | PHB | 5245 | pd | > | reg.ITFP.txt: no annot |
RASSF7 | 8045 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
ETF1 | 2107 | GSPT1 | 2935 | pp | -- | int.I2D: MINT, BCI, BioGrid, HPRD; int.Mint: MI:0915(physical association); int.HPRD: in vivo, yeast 2-hybrid |
CDKN2A | 1029 | HNRNPU | 3192 | pp | -- | int.Intact: MI:0915(physical association) |
GTF3C2 | 2976 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
WDR18 | 57418 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
VARS | 7407 | WDR18 | 57418 | pd | <> | reg.ITFP.txt: no annot |
NOLC1 | 9221 | WDR18 | 57418 | pd | <> | reg.ITFP.txt: no annot |
SUV39H2 | 79723 | TMEM68 | 137695 | pd | < | reg.ITFP.txt: no annot |
POLH | 5429 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
GTF3C2 | 2976 | NOLC1 | 9221 | pd | <> | reg.ITFP.txt: no annot |
RAE1 | 8480 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
DDIT3 | 1649 | NONO | 4841 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
NFRKB | 4798 | NONO | 4841 | pd | < | reg.ITFP.txt: no annot |
NFRKB | 4798 | YY1 | 7528 | pp | -- | int.I2D: BioGrid |
GSPT1 | 2935 | SYNCRIP | 10492 | pd | < | reg.ITFP.txt: no annot |
CDKN2A | 1029 | FTSJ1 | 24140 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
CCT7 | 10574 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
RAE1 | 8480 | NOLC1 | 9221 | pd | <> | reg.ITFP.txt: no annot |
RNF40 | 9810 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
CDKN2A | 1029 | GSPT1 | 2935 | pp | -- | int.I2D: BCI; int.HPRD: in vitro, in vivo, yeast 2-hybrid |
VARS | 7407 | FTSJ1 | 24140 | pd | > | reg.ITFP.txt: no annot |
DRG2 | 1819 | GTF3C2 | 2976 | pd | < | reg.ITFP.txt: no annot |
SYNCRIP | 10492 | WDR18 | 57418 | pd | <> | reg.ITFP.txt: no annot |
FBXO22 | 26263 | WDR18 | 57418 | pd | <> | reg.ITFP.txt: no annot |
FBXO22 | 26263 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
NONO | 4841 | FTSJ1 | 24140 | pd | > | reg.ITFP.txt: no annot |
VARS | 7407 | FBXL6 | 26233 | pd | > | reg.ITFP.txt: no annot |
KLC3 | 147700 | LCE1E | 353135 | pd | > | reg.ITFP.txt: no annot |
DRG2 | 1819 | NONO | 4841 | pd | < | reg.ITFP.txt: no annot |
CHERP | 10523 | LCE1E | 353135 | pd | > | reg.ITFP.txt: no annot |
DDIT3 | 1649 | VARS | 7407 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
NONO | 4841 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
ETF1 | 2107 | EIF2S2 | 8894 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
GTF3C2 | 2976 | WDR18 | 57418 | pd | <> | reg.ITFP.txt: no annot |
GTF3C2 | 2976 | RAE1 | 8480 | pd | <> | reg.ITFP.txt: no annot |
CPSF3 | 51692 | TMEM68 | 137695 | pd | < | reg.ITFP.txt: no annot |
RNF40 | 9810 | KLC3 | 147700 | pd | <> | reg.ITFP.txt: no annot |
EDC3 | 80153 | KLC3 | 147700 | pd | < | reg.ITFP.txt: no annot |
FBXL6 | 26233 | WDR18 | 57418 | pd | < | reg.ITFP.txt: no annot |
BEST1 | 7439 | CHERP | 10523 | pd | < | reg.ITFP.txt: no annot |
CDKN2A | 1029 | E4F1 | 1877 | pp | -- | int.I2D: BioGrid; int.HPRD: in vivo |
SYNCRIP | 10492 | CPSF3 | 51692 | pd | > | reg.ITFP.txt: no annot |
CHERP | 10523 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
GTF3C2 | 2976 | NONO | 4841 | pd | <> | reg.ITFP.txt: no annot |
GPS1 | 2873 | WDR18 | 57418 | pd | <> | reg.ITFP.txt: no annot |
SYNCRIP | 10492 | SUV39H2 | 79723 | pd | > | reg.ITFP.txt: no annot |
RASSF7 | 8045 | CHERP | 10523 | pd | <> | reg.ITFP.txt: no annot |
HNRNPU | 3192 | NONO | 4841 | pd | < | reg.ITFP.txt: no annot |
NONO | 4841 | RAE1 | 8480 | pd | <> | reg.ITFP.txt: no annot |
NCBP1 | 4686 | RNF40 | 9810 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, VidalHuman_core; int.HPRD: yeast 2-hybrid |
PHB | 5245 | WDR18 | 57418 | pd | < | reg.ITFP.txt: no annot |
CDKN2A | 1029 | YY1 | 7528 | pd | < | reg.TRANSFAC.txt: no annot |
CDKN2A | 1029 | YY1 | 7528 | pp | -- | int.I2D: BioGrid, BIND, BCI |
RASSF7 | 8045 | KLC3 | 147700 | pd | <> | reg.ITFP.txt: no annot |
GTF3C2 | 2976 | CNOT1 | 23019 | pd | > | reg.ITFP.txt: no annot |
EDC3 | 80153 | TMEM68 | 137695 | pd | < | reg.ITFP.txt: no annot |
RAE1 | 8480 | CPSF3 | 51692 | pd | > | reg.ITFP.txt: no annot |
NOLC1 | 9221 | FTSJ1 | 24140 | pd | > | reg.ITFP.txt: no annot |
GSPT1 | 2935 | NOLC1 | 9221 | pd | < | reg.ITFP.txt: no annot |
VARS | 7407 | FBXO22 | 26263 | pd | <> | reg.ITFP.txt: no annot |
PHB | 5245 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
HNRNPU | 3192 | SYNCRIP | 10492 | pp | -- | int.Mint: MI:0915(physical association) |
FBXO22 | 26263 | NDUFA4L2 | 56901 | pd | > | reg.ITFP.txt: no annot |
RAE1 | 8480 | WDR18 | 57418 | pd | <> | reg.ITFP.txt: no annot |
NOLC1 | 9221 | EDC3 | 80153 | pd | > | reg.ITFP.txt: no annot |
NONO | 4841 | FBXO22 | 26263 | pd | <> | reg.ITFP.txt: no annot |
FTSJ1 | 24140 | WDR18 | 57418 | pd | < | reg.ITFP.txt: no annot |
EIF2S2 | 8894 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
CCT7 | 10574 | WDR18 | 57418 | pd | < | reg.ITFP.txt: no annot |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0003723 | RNA binding | 1.17e-07 | 1.92e-03 | 3.407 | 9 | 15 | 355 |
GO:0005654 | nucleoplasm | 8.17e-07 | 1.33e-02 | 2.313 | 13 | 31 | 1095 |
GO:0010467 | gene expression | 2.71e-06 | 4.42e-02 | 2.645 | 10 | 27 | 669 |
GO:0044822 | poly(A) RNA binding | 4.78e-06 | 7.80e-02 | 2.220 | 12 | 27 | 1078 |
GO:0003747 | translation release factor activity | 3.33e-05 | 5.43e-01 | 7.709 | 2 | 2 | 4 |
GO:0044212 | transcription regulatory region DNA binding | 5.14e-05 | 8.39e-01 | 3.613 | 5 | 5 | 171 |
GO:0070934 | CRD-mediated mRNA stabilization | 5.54e-05 | 9.04e-01 | 7.387 | 2 | 2 | 5 |
GO:0070937 | CRD-mediated mRNA stability complex | 8.30e-05 | 1.00e+00 | 7.124 | 2 | 2 | 6 |
GO:0030529 | ribonucleoprotein complex | 1.54e-04 | 1.00e+00 | 3.876 | 4 | 6 | 114 |
GO:0005515 | protein binding | 2.11e-04 | 1.00e+00 | 0.829 | 26 | 77 | 6127 |
GO:0008380 | RNA splicing | 2.16e-04 | 1.00e+00 | 3.173 | 5 | 14 | 232 |
GO:0006379 | mRNA cleavage | 2.47e-04 | 1.00e+00 | 6.387 | 2 | 2 | 10 |
GO:0010225 | response to UV-C | 2.47e-04 | 1.00e+00 | 6.387 | 2 | 2 | 10 |
GO:0006396 | RNA processing | 3.93e-04 | 1.00e+00 | 4.387 | 3 | 4 | 60 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 4.27e-04 | 1.00e+00 | 6.009 | 2 | 2 | 13 |
GO:0006406 | mRNA export from nucleus | 4.33e-04 | 1.00e+00 | 4.340 | 3 | 5 | 62 |
GO:0031011 | Ino80 complex | 4.97e-04 | 1.00e+00 | 5.902 | 2 | 2 | 14 |
GO:0006479 | protein methylation | 5.73e-04 | 1.00e+00 | 5.802 | 2 | 2 | 15 |
GO:0000398 | mRNA splicing, via spliceosome | 6.29e-04 | 1.00e+00 | 3.343 | 4 | 9 | 165 |
GO:0003714 | transcription corepressor activity | 8.53e-04 | 1.00e+00 | 3.225 | 4 | 5 | 179 |
GO:0001649 | osteoblast differentiation | 1.50e-03 | 1.00e+00 | 3.724 | 3 | 3 | 95 |
GO:0031047 | gene silencing by RNA | 1.74e-03 | 1.00e+00 | 5.009 | 2 | 2 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 1.74e-03 | 1.00e+00 | 5.009 | 2 | 2 | 26 |
GO:0016071 | mRNA metabolic process | 1.92e-03 | 1.00e+00 | 2.908 | 4 | 8 | 223 |
GO:0002128 | tRNA nucleoside ribose methylation | 2.39e-03 | 1.00e+00 | 8.709 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 2.39e-03 | 1.00e+00 | 8.709 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 2.39e-03 | 1.00e+00 | 8.709 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 2.39e-03 | 1.00e+00 | 8.709 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 2.39e-03 | 1.00e+00 | 8.709 | 1 | 1 | 1 |
GO:0008079 | translation termination factor activity | 2.39e-03 | 1.00e+00 | 8.709 | 1 | 1 | 1 |
GO:0009794 | regulation of mitotic cell cycle, embryonic | 2.39e-03 | 1.00e+00 | 8.709 | 1 | 1 | 1 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 2.53e-03 | 1.00e+00 | 3.461 | 3 | 3 | 114 |
GO:0016070 | RNA metabolic process | 2.78e-03 | 1.00e+00 | 2.761 | 4 | 8 | 247 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.21e-03 | 1.00e+00 | 2.303 | 5 | 7 | 424 |
GO:0031124 | mRNA 3'-end processing | 4.51e-03 | 1.00e+00 | 4.317 | 2 | 4 | 42 |
GO:0004832 | valine-tRNA ligase activity | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0006403 | RNA localization | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0008175 | tRNA methyltransferase activity | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0005846 | nuclear cap binding complex | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0002176 | male germ cell proliferation | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0055105 | ubiquitin-protein transferase inhibitor activity | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0060965 | negative regulation of gene silencing by miRNA | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0034696 | response to prostaglandin F | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 2 |
GO:0006369 | termination of RNA polymerase II transcription | 5.16e-03 | 1.00e+00 | 4.217 | 2 | 4 | 45 |
GO:0006974 | cellular response to DNA damage stimulus | 6.30e-03 | 1.00e+00 | 2.990 | 3 | 4 | 158 |
GO:0005737 | cytoplasm | 6.51e-03 | 1.00e+00 | 0.839 | 17 | 43 | 3976 |
GO:0016020 | membrane | 6.65e-03 | 1.00e+00 | 1.261 | 10 | 27 | 1746 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 7.10e-03 | 1.00e+00 | 3.981 | 2 | 2 | 53 |
GO:0036123 | histone H3-K9 dimethylation | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 1 | 3 |
GO:0035986 | senescence-associated heterochromatin focus assembly | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 1 | 3 |
GO:2000111 | positive regulation of macrophage apoptotic process | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 1 | 3 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 2 | 3 |
GO:0016149 | translation release factor activity, codon specific | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 1 | 3 |
GO:0035985 | senescence-associated heterochromatin focus | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 7.15e-03 | 1.00e+00 | 7.124 | 1 | 1 | 3 |
GO:0000932 | cytoplasmic mRNA processing body | 7.90e-03 | 1.00e+00 | 3.902 | 2 | 2 | 56 |
GO:2000774 | positive regulation of cellular senescence | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:0097452 | GAIT complex | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 2 | 4 |
GO:0051533 | positive regulation of NFAT protein import into nucleus | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:0060913 | cardiac cell fate determination | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:0007000 | nucleolus organization | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:0033503 | HULC complex | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:0006290 | pyrimidine dimer repair | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:0033088 | negative regulation of immature T cell proliferation in thymus | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 4 |
GO:0006310 | DNA recombination | 1.12e-02 | 1.00e+00 | 3.643 | 2 | 2 | 67 |
GO:0001714 | endodermal cell fate specification | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:1902510 | regulation of apoptotic DNA fragmentation | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0030321 | transepithelial chloride transport | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0034393 | positive regulation of smooth muscle cell apoptotic process | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0097371 | MDM2/MDM4 family protein binding | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0048742 | regulation of skeletal muscle fiber development | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0006398 | histone mRNA 3'-end processing | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0045292 | mRNA cis splicing, via spliceosome | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0031442 | positive regulation of mRNA 3'-end processing | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0006449 | regulation of translational termination | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0036124 | histone H3-K9 trimethylation | 1.19e-02 | 1.00e+00 | 6.387 | 1 | 1 | 5 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1.26e-02 | 1.00e+00 | 1.829 | 5 | 10 | 589 |
GO:0003677 | DNA binding | 1.31e-02 | 1.00e+00 | 1.309 | 8 | 16 | 1351 |
GO:0005829 | cytosol | 1.36e-02 | 1.00e+00 | 0.971 | 12 | 38 | 2562 |
GO:0042797 | tRNA transcription from RNA polymerase III promoter | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 2 | 6 |
GO:0010564 | regulation of cell cycle process | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:0050847 | progesterone receptor signaling pathway | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:0002181 | cytoplasmic translation | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:0046974 | histone methyltransferase activity (H3-K9 specific) | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:0000127 | transcription factor TFIIIC complex | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 2 | 6 |
GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 2 | 6 |
GO:0006333 | chromatin assembly or disassembly | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:0071204 | histone pre-mRNA 3'end processing complex | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:0035497 | cAMP response element binding | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 1 | 6 |
GO:0042382 | paraspeckles | 1.43e-02 | 1.00e+00 | 6.124 | 1 | 2 | 6 |
GO:0071013 | catalytic step 2 spliceosome | 1.53e-02 | 1.00e+00 | 3.405 | 2 | 3 | 79 |
GO:0046825 | regulation of protein export from nucleus | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 2 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 1 | 7 |
GO:0004521 | endoribonuclease activity | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 1 | 7 |
GO:0006301 | postreplication repair | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 1 | 7 |
GO:0051444 | negative regulation of ubiquitin-protein transferase activity | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 1 | 7 |
GO:0006282 | regulation of DNA repair | 1.66e-02 | 1.00e+00 | 5.902 | 1 | 1 | 7 |
GO:0006366 | transcription from RNA polymerase II promoter | 1.82e-02 | 1.00e+00 | 1.978 | 4 | 14 | 425 |
GO:0006415 | translational termination | 1.83e-02 | 1.00e+00 | 3.266 | 2 | 2 | 87 |
GO:0042754 | negative regulation of circadian rhythm | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 1 | 8 |
GO:0001955 | blood vessel maturation | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 1 | 8 |
GO:0000339 | RNA cap binding | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 1 | 8 |
GO:0033523 | histone H2B ubiquitination | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 1 | 8 |
GO:0003713 | transcription coactivator activity | 1.92e-02 | 1.00e+00 | 2.393 | 3 | 7 | 239 |
GO:0016363 | nuclear matrix | 2.03e-02 | 1.00e+00 | 3.185 | 2 | 5 | 92 |
GO:0008134 | transcription factor binding | 2.07e-02 | 1.00e+00 | 2.351 | 3 | 6 | 246 |
GO:0071354 | cellular response to interleukin-6 | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0008409 | 5'-3' exonuclease activity | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0048103 | somatic stem cell division | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0010388 | cullin deneddylation | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 5 | 9 |
GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0035253 | ciliary rootlet | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0000400 | four-way junction DNA binding | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0005832 | chaperonin-containing T-complex | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 9 |
GO:0006364 | rRNA processing | 2.20e-02 | 1.00e+00 | 3.124 | 2 | 2 | 96 |
GO:0004842 | ubiquitin-protein transferase activity | 2.30e-02 | 1.00e+00 | 2.294 | 3 | 5 | 256 |
GO:0002199 | zona pellucida receptor complex | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 10 |
GO:0006450 | regulation of translational fidelity | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 10 |
GO:0008088 | axon cargo transport | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 10 |
GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 10 |
GO:0090399 | replicative senescence | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 10 |
GO:0000731 | DNA synthesis involved in DNA repair | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 10 |
GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 2 | 10 |
GO:0010944 | negative regulation of transcription by competitive promoter binding | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 10 |
GO:0006281 | DNA repair | 2.49e-02 | 1.00e+00 | 2.250 | 3 | 4 | 264 |
GO:0005845 | mRNA cap binding complex | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0048387 | negative regulation of retinoic acid receptor signaling pathway | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0071850 | mitotic cell cycle arrest | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0045662 | negative regulation of myoblast differentiation | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0010390 | histone monoubiquitination | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0033235 | positive regulation of protein sumoylation | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0035413 | positive regulation of catenin import into nucleus | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0004535 | poly(A)-specific ribonuclease activity | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:2000036 | regulation of stem cell maintenance | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 2.60e-02 | 1.00e+00 | 5.250 | 1 | 1 | 11 |
GO:0008334 | histone mRNA metabolic process | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 12 |
GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 12 |
GO:0001953 | negative regulation of cell-matrix adhesion | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 12 |
GO:0008143 | poly(A) binding | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 2 | 12 |
GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 12 |
GO:0044267 | cellular protein metabolic process | 2.98e-02 | 1.00e+00 | 1.758 | 4 | 7 | 495 |
GO:0030308 | negative regulation of cell growth | 2.98e-02 | 1.00e+00 | 2.889 | 2 | 2 | 113 |
GO:0007140 | male meiosis | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 13 |
GO:0042974 | retinoic acid receptor binding | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 13 |
GO:0060766 | negative regulation of androgen receptor signaling pathway | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 13 |
GO:0035198 | miRNA binding | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 13 |
GO:0000209 | protein polyubiquitination | 3.13e-02 | 1.00e+00 | 2.851 | 2 | 5 | 116 |
GO:0071480 | cellular response to gamma radiation | 3.30e-02 | 1.00e+00 | 4.902 | 1 | 1 | 14 |
GO:0005095 | GTPase inhibitor activity | 3.30e-02 | 1.00e+00 | 4.902 | 1 | 1 | 14 |
GO:0030889 | negative regulation of B cell proliferation | 3.30e-02 | 1.00e+00 | 4.902 | 1 | 1 | 14 |
GO:0050908 | detection of light stimulus involved in visual perception | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 15 |
GO:0001824 | blastocyst development | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 15 |
GO:0030014 | CCR4-NOT complex | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 15 |
GO:0006260 | DNA replication | 3.59e-02 | 1.00e+00 | 2.743 | 2 | 4 | 125 |
GO:0005739 | mitochondrion | 3.63e-02 | 1.00e+00 | 1.263 | 6 | 16 | 1046 |
GO:0007050 | cell cycle arrest | 3.64e-02 | 1.00e+00 | 2.732 | 2 | 3 | 126 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 3.69e-02 | 1.00e+00 | 2.720 | 2 | 3 | 127 |
GO:0016746 | transferase activity, transferring acyl groups | 3.76e-02 | 1.00e+00 | 4.709 | 1 | 2 | 16 |
GO:0051276 | chromosome organization | 3.76e-02 | 1.00e+00 | 4.709 | 1 | 2 | 16 |
GO:0016032 | viral process | 3.91e-02 | 1.00e+00 | 1.632 | 4 | 16 | 540 |
GO:0001829 | trophectodermal cell differentiation | 3.99e-02 | 1.00e+00 | 4.622 | 1 | 2 | 17 |
GO:0048593 | camera-type eye morphogenesis | 3.99e-02 | 1.00e+00 | 4.622 | 1 | 1 | 17 |
GO:0005730 | nucleolus | 4.27e-02 | 1.00e+00 | 0.991 | 8 | 28 | 1684 |
GO:0005525 | GTP binding | 4.32e-02 | 1.00e+00 | 1.936 | 3 | 5 | 328 |
GO:0005634 | nucleus | 4.40e-02 | 1.00e+00 | 0.559 | 17 | 55 | 4828 |
GO:0017075 | syntaxin-1 binding | 4.45e-02 | 1.00e+00 | 4.461 | 1 | 1 | 19 |
GO:0071158 | positive regulation of cell cycle arrest | 4.45e-02 | 1.00e+00 | 4.461 | 1 | 1 | 19 |
GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | 4.45e-02 | 1.00e+00 | 4.461 | 1 | 2 | 19 |
GO:0090398 | cellular senescence | 4.67e-02 | 1.00e+00 | 4.387 | 1 | 1 | 20 |
GO:0001227 | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 4.67e-02 | 1.00e+00 | 4.387 | 1 | 1 | 20 |
GO:0032757 | positive regulation of interleukin-8 production | 4.90e-02 | 1.00e+00 | 4.317 | 1 | 1 | 21 |
GO:0031648 | protein destabilization | 4.90e-02 | 1.00e+00 | 4.317 | 1 | 2 | 21 |
GO:0042326 | negative regulation of phosphorylation | 4.90e-02 | 1.00e+00 | 4.317 | 1 | 1 | 21 |
GO:0016575 | histone deacetylation | 4.90e-02 | 1.00e+00 | 4.317 | 1 | 1 | 21 |
GO:0008637 | apoptotic mitochondrial changes | 4.90e-02 | 1.00e+00 | 4.317 | 1 | 1 | 21 |
GO:0008017 | microtubule binding | 4.98e-02 | 1.00e+00 | 2.480 | 2 | 4 | 150 |
GO:0000082 | G1/S transition of mitotic cell cycle | 4.98e-02 | 1.00e+00 | 2.480 | 2 | 4 | 150 |
GO:0051924 | regulation of calcium ion transport | 5.13e-02 | 1.00e+00 | 4.250 | 1 | 1 | 22 |
GO:0005720 | nuclear heterochromatin | 5.13e-02 | 1.00e+00 | 4.250 | 1 | 1 | 22 |
GO:0006378 | mRNA polyadenylation | 5.13e-02 | 1.00e+00 | 4.250 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 5.13e-02 | 1.00e+00 | 4.250 | 1 | 1 | 22 |
GO:0071346 | cellular response to interferon-gamma | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 2 | 23 |
GO:0034660 | ncRNA metabolic process | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 1 | 23 |
GO:0005640 | nuclear outer membrane | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 1 | 23 |
GO:0008135 | translation factor activity, nucleic acid binding | 5.58e-02 | 1.00e+00 | 4.124 | 1 | 2 | 24 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 5.58e-02 | 1.00e+00 | 4.124 | 1 | 1 | 24 |
GO:0043005 | neuron projection | 5.65e-02 | 1.00e+00 | 2.378 | 2 | 4 | 161 |
GO:0008285 | negative regulation of cell proliferation | 5.68e-02 | 1.00e+00 | 1.774 | 3 | 4 | 367 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 5.81e-02 | 1.00e+00 | 4.065 | 1 | 1 | 25 |
GO:0031519 | PcG protein complex | 5.81e-02 | 1.00e+00 | 4.065 | 1 | 1 | 25 |
GO:0051059 | NF-kappaB binding | 5.81e-02 | 1.00e+00 | 4.065 | 1 | 2 | 25 |
GO:0035329 | hippo signaling | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 1 | 26 |
GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 1 | 26 |
GO:0031424 | keratinization | 6.26e-02 | 1.00e+00 | 3.954 | 1 | 1 | 27 |
GO:0006913 | nucleocytoplasmic transport | 6.26e-02 | 1.00e+00 | 3.954 | 1 | 1 | 27 |
GO:0000188 | inactivation of MAPK activity | 6.26e-02 | 1.00e+00 | 3.954 | 1 | 1 | 27 |
GO:0030331 | estrogen receptor binding | 6.26e-02 | 1.00e+00 | 3.954 | 1 | 2 | 27 |
GO:0000387 | spliceosomal snRNP assembly | 6.26e-02 | 1.00e+00 | 3.954 | 1 | 1 | 27 |
GO:0007339 | binding of sperm to zona pellucida | 6.26e-02 | 1.00e+00 | 3.954 | 1 | 1 | 27 |
GO:0000976 | transcription regulatory region sequence-specific DNA binding | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 1 | 28 |
GO:0043022 | ribosome binding | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 2 | 28 |
GO:0033017 | sarcoplasmic reticulum membrane | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 1 | 28 |
GO:0019894 | kinesin binding | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 1 | 28 |
GO:0007049 | cell cycle | 6.67e-02 | 1.00e+00 | 2.241 | 2 | 4 | 177 |
GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 1 | 29 |
GO:0003887 | DNA-directed DNA polymerase activity | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 1 | 29 |
GO:0071897 | DNA biosynthetic process | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 1 | 29 |
GO:0005667 | transcription factor complex | 6.74e-02 | 1.00e+00 | 2.233 | 2 | 3 | 178 |
GO:0031625 | ubiquitin protein ligase binding | 6.87e-02 | 1.00e+00 | 2.217 | 2 | 2 | 180 |
GO:0006370 | 7-methylguanosine mRNA capping | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 2 | 30 |
GO:0031647 | regulation of protein stability | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 2 | 30 |
GO:0010827 | regulation of glucose transport | 7.15e-02 | 1.00e+00 | 3.755 | 1 | 3 | 31 |
GO:0016604 | nuclear body | 7.15e-02 | 1.00e+00 | 3.755 | 1 | 1 | 31 |
GO:0070534 | protein K63-linked ubiquitination | 7.15e-02 | 1.00e+00 | 3.755 | 1 | 1 | 31 |
GO:0042594 | response to starvation | 7.38e-02 | 1.00e+00 | 3.709 | 1 | 3 | 32 |
GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | 7.38e-02 | 1.00e+00 | 3.709 | 1 | 1 | 32 |
GO:0034644 | cellular response to UV | 7.38e-02 | 1.00e+00 | 3.709 | 1 | 1 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 7.38e-02 | 1.00e+00 | 3.709 | 1 | 1 | 32 |
GO:0008180 | COP9 signalosome | 7.82e-02 | 1.00e+00 | 3.622 | 1 | 6 | 34 |
GO:0006351 | transcription, DNA-templated | 7.89e-02 | 1.00e+00 | 0.886 | 7 | 17 | 1585 |
GO:0009267 | cellular response to starvation | 8.26e-02 | 1.00e+00 | 3.539 | 1 | 1 | 36 |
GO:0006446 | regulation of translational initiation | 8.26e-02 | 1.00e+00 | 3.539 | 1 | 2 | 36 |
GO:0007077 | mitotic nuclear envelope disassembly | 8.48e-02 | 1.00e+00 | 3.500 | 1 | 3 | 37 |
GO:0006821 | chloride transport | 8.48e-02 | 1.00e+00 | 3.500 | 1 | 1 | 37 |
GO:0051084 | 'de novo' posttranslational protein folding | 8.48e-02 | 1.00e+00 | 3.500 | 1 | 1 | 37 |
GO:0042752 | regulation of circadian rhythm | 8.48e-02 | 1.00e+00 | 3.500 | 1 | 3 | 37 |
GO:0006383 | transcription from RNA polymerase III promoter | 8.92e-02 | 1.00e+00 | 3.424 | 1 | 3 | 39 |
GO:0071407 | cellular response to organic cyclic compound | 8.92e-02 | 1.00e+00 | 3.424 | 1 | 3 | 39 |
GO:0035019 | somatic stem cell maintenance | 9.14e-02 | 1.00e+00 | 3.387 | 1 | 2 | 40 |
GO:0034707 | chloride channel complex | 9.14e-02 | 1.00e+00 | 3.387 | 1 | 1 | 40 |
GO:0005254 | chloride channel activity | 9.35e-02 | 1.00e+00 | 3.351 | 1 | 1 | 41 |
GO:0017148 | negative regulation of translation | 9.35e-02 | 1.00e+00 | 3.351 | 1 | 3 | 41 |
GO:0006418 | tRNA aminoacylation for protein translation | 9.57e-02 | 1.00e+00 | 3.317 | 1 | 3 | 42 |
GO:0008645 | hexose transport | 9.57e-02 | 1.00e+00 | 3.317 | 1 | 3 | 42 |
GO:0031514 | motile cilium | 9.57e-02 | 1.00e+00 | 3.317 | 1 | 1 | 42 |
GO:0016874 | ligase activity | 9.99e-02 | 1.00e+00 | 1.902 | 2 | 4 | 224 |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 1.00e-01 | 1.00e+00 | 3.250 | 1 | 1 | 44 |
GO:0005871 | kinesin complex | 1.00e-01 | 1.00e+00 | 3.250 | 1 | 1 | 44 |
GO:0050434 | positive regulation of viral transcription | 1.00e-01 | 1.00e+00 | 3.250 | 1 | 2 | 44 |
GO:0015030 | Cajal body | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 1 | 45 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 1.02e-01 | 1.00e+00 | 1.162 | 4 | 10 | 748 |
GO:0001047 | core promoter binding | 1.04e-01 | 1.00e+00 | 3.185 | 1 | 2 | 46 |
GO:0044297 | cell body | 1.04e-01 | 1.00e+00 | 3.185 | 1 | 1 | 46 |
GO:0043525 | positive regulation of neuron apoptotic process | 1.04e-01 | 1.00e+00 | 3.185 | 1 | 2 | 46 |
GO:0007067 | mitotic nuclear division | 1.05e-01 | 1.00e+00 | 1.857 | 2 | 4 | 231 |
GO:0048511 | rhythmic process | 1.06e-01 | 1.00e+00 | 3.154 | 1 | 2 | 47 |
GO:0006412 | translation | 1.08e-01 | 1.00e+00 | 1.833 | 2 | 5 | 235 |
GO:0045893 | positive regulation of transcription, DNA-templated | 1.10e-01 | 1.00e+00 | 1.366 | 3 | 6 | 487 |
GO:0003743 | translation initiation factor activity | 1.11e-01 | 1.00e+00 | 3.094 | 1 | 5 | 49 |
GO:0042802 | identical protein binding | 1.12e-01 | 1.00e+00 | 1.354 | 3 | 6 | 491 |
GO:0005778 | peroxisomal membrane | 1.13e-01 | 1.00e+00 | 3.065 | 1 | 2 | 50 |
GO:0006986 | response to unfolded protein | 1.15e-01 | 1.00e+00 | 3.037 | 1 | 2 | 51 |
GO:0040008 | regulation of growth | 1.15e-01 | 1.00e+00 | 3.037 | 1 | 1 | 51 |
GO:0007254 | JNK cascade | 1.15e-01 | 1.00e+00 | 3.037 | 1 | 2 | 51 |
GO:0003684 | damaged DNA binding | 1.15e-01 | 1.00e+00 | 3.037 | 1 | 1 | 51 |
GO:0000775 | chromosome, centromeric region | 1.17e-01 | 1.00e+00 | 3.009 | 1 | 3 | 52 |
GO:0034976 | response to endoplasmic reticulum stress | 1.17e-01 | 1.00e+00 | 3.009 | 1 | 1 | 52 |
GO:0045454 | cell redox homeostasis | 1.17e-01 | 1.00e+00 | 3.009 | 1 | 1 | 52 |
GO:0009611 | response to wounding | 1.19e-01 | 1.00e+00 | 2.981 | 1 | 1 | 53 |
GO:0007623 | circadian rhythm | 1.21e-01 | 1.00e+00 | 2.954 | 1 | 2 | 54 |
GO:0006355 | regulation of transcription, DNA-templated | 1.21e-01 | 1.00e+00 | 0.922 | 5 | 13 | 1104 |
GO:0002039 | p53 binding | 1.23e-01 | 1.00e+00 | 2.928 | 1 | 3 | 55 |
GO:0005874 | microtubule | 1.26e-01 | 1.00e+00 | 1.698 | 2 | 3 | 258 |
GO:0000724 | double-strand break repair via homologous recombination | 1.28e-01 | 1.00e+00 | 2.876 | 1 | 1 | 57 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 1.32e-01 | 1.00e+00 | 2.826 | 1 | 2 | 59 |
GO:0015758 | glucose transport | 1.32e-01 | 1.00e+00 | 2.826 | 1 | 3 | 59 |
GO:0005643 | nuclear pore | 1.32e-01 | 1.00e+00 | 2.826 | 1 | 3 | 59 |
GO:0003777 | microtubule motor activity | 1.34e-01 | 1.00e+00 | 2.802 | 1 | 1 | 60 |
GO:0000166 | nucleotide binding | 1.37e-01 | 1.00e+00 | 1.622 | 2 | 6 | 272 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 1.38e-01 | 1.00e+00 | 2.755 | 1 | 2 | 62 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 1.38e-01 | 1.00e+00 | 2.755 | 1 | 1 | 62 |
GO:0000151 | ubiquitin ligase complex | 1.40e-01 | 1.00e+00 | 2.732 | 1 | 2 | 63 |
GO:0006417 | regulation of translation | 1.40e-01 | 1.00e+00 | 2.732 | 1 | 1 | 63 |
GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 1.42e-01 | 1.00e+00 | 2.709 | 1 | 2 | 64 |
GO:0006469 | negative regulation of protein kinase activity | 1.44e-01 | 1.00e+00 | 2.687 | 1 | 2 | 65 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 1.48e-01 | 1.00e+00 | 2.643 | 1 | 3 | 67 |
GO:0006338 | chromatin remodeling | 1.50e-01 | 1.00e+00 | 2.622 | 1 | 1 | 68 |
GO:1902476 | chloride transmembrane transport | 1.54e-01 | 1.00e+00 | 2.580 | 1 | 1 | 70 |
GO:0010468 | regulation of gene expression | 1.59e-01 | 1.00e+00 | 2.539 | 1 | 1 | 72 |
GO:0016567 | protein ubiquitination | 1.60e-01 | 1.00e+00 | 1.485 | 2 | 5 | 299 |
GO:0000785 | chromatin | 1.61e-01 | 1.00e+00 | 2.519 | 1 | 2 | 73 |
GO:0008152 | metabolic process | 1.62e-01 | 1.00e+00 | 1.471 | 2 | 2 | 302 |
GO:0002020 | protease binding | 1.63e-01 | 1.00e+00 | 2.500 | 1 | 1 | 74 |
GO:0042826 | histone deacetylase binding | 1.63e-01 | 1.00e+00 | 2.500 | 1 | 2 | 74 |
GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 1.65e-01 | 1.00e+00 | 2.480 | 1 | 1 | 75 |
GO:0007265 | Ras protein signal transduction | 1.65e-01 | 1.00e+00 | 2.480 | 1 | 2 | 75 |
GO:0006874 | cellular calcium ion homeostasis | 1.67e-01 | 1.00e+00 | 2.461 | 1 | 1 | 76 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 1.67e-01 | 1.00e+00 | 2.461 | 1 | 2 | 76 |
GO:0044325 | ion channel binding | 1.69e-01 | 1.00e+00 | 2.442 | 1 | 1 | 77 |
GO:0008584 | male gonad development | 1.69e-01 | 1.00e+00 | 2.442 | 1 | 1 | 77 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 1.69e-01 | 1.00e+00 | 2.442 | 1 | 2 | 77 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 1.69e-01 | 1.00e+00 | 2.442 | 1 | 2 | 77 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 1.77e-01 | 1.00e+00 | 2.369 | 1 | 2 | 81 |
GO:0030154 | cell differentiation | 1.82e-01 | 1.00e+00 | 1.365 | 2 | 2 | 325 |
GO:0009952 | anterior/posterior pattern specification | 1.82e-01 | 1.00e+00 | 2.317 | 1 | 2 | 84 |
GO:0008283 | cell proliferation | 1.87e-01 | 1.00e+00 | 1.338 | 2 | 3 | 331 |
GO:0009653 | anatomical structure morphogenesis | 1.88e-01 | 1.00e+00 | 2.266 | 1 | 1 | 87 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 1.90e-01 | 1.00e+00 | 2.250 | 1 | 4 | 88 |
GO:0006464 | cellular protein modification process | 1.92e-01 | 1.00e+00 | 2.233 | 1 | 1 | 89 |
GO:0050821 | protein stabilization | 1.96e-01 | 1.00e+00 | 2.201 | 1 | 3 | 91 |
GO:0005770 | late endosome | 2.02e-01 | 1.00e+00 | 2.154 | 1 | 1 | 94 |
GO:0051082 | unfolded protein binding | 2.04e-01 | 1.00e+00 | 2.139 | 1 | 3 | 95 |
GO:0030018 | Z disc | 2.10e-01 | 1.00e+00 | 2.094 | 1 | 2 | 98 |
GO:0071456 | cellular response to hypoxia | 2.10e-01 | 1.00e+00 | 2.094 | 1 | 2 | 98 |
GO:0043565 | sequence-specific DNA binding | 2.17e-01 | 1.00e+00 | 1.197 | 2 | 3 | 365 |
GO:0005815 | microtubule organizing center | 2.32e-01 | 1.00e+00 | 1.928 | 1 | 1 | 110 |
GO:0005819 | spindle | 2.39e-01 | 1.00e+00 | 1.876 | 1 | 2 | 114 |
GO:0005635 | nuclear envelope | 2.43e-01 | 1.00e+00 | 1.851 | 1 | 3 | 116 |
GO:0000278 | mitotic cell cycle | 2.46e-01 | 1.00e+00 | 1.072 | 2 | 12 | 398 |
GO:0006413 | translational initiation | 2.70e-01 | 1.00e+00 | 1.676 | 1 | 4 | 131 |
GO:0016055 | Wnt signaling pathway | 2.87e-01 | 1.00e+00 | 1.569 | 1 | 3 | 141 |
GO:0006457 | protein folding | 3.01e-01 | 1.00e+00 | 1.490 | 1 | 1 | 149 |
GO:0016323 | basolateral plasma membrane | 3.01e-01 | 1.00e+00 | 1.490 | 1 | 1 | 149 |
GO:0042981 | regulation of apoptotic process | 3.04e-01 | 1.00e+00 | 1.471 | 1 | 3 | 151 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 3.06e-01 | 1.00e+00 | 0.630 | 3 | 13 | 811 |
GO:0034220 | ion transmembrane transport | 3.31e-01 | 1.00e+00 | 1.325 | 1 | 1 | 167 |
GO:0007601 | visual perception | 3.32e-01 | 1.00e+00 | 1.317 | 1 | 1 | 168 |
GO:0006397 | mRNA processing | 3.34e-01 | 1.00e+00 | 1.308 | 1 | 6 | 169 |
GO:0016607 | nuclear speck | 3.44e-01 | 1.00e+00 | 1.258 | 1 | 6 | 175 |
GO:0055085 | transmembrane transport | 3.49e-01 | 1.00e+00 | 0.703 | 2 | 5 | 514 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 3.58e-01 | 1.00e+00 | 1.185 | 1 | 5 | 184 |
GO:0032403 | protein complex binding | 3.59e-01 | 1.00e+00 | 1.178 | 1 | 2 | 185 |
GO:0003924 | GTPase activity | 3.87e-01 | 1.00e+00 | 1.044 | 1 | 2 | 203 |
GO:0001701 | in utero embryonic development | 3.97e-01 | 1.00e+00 | 0.995 | 1 | 2 | 210 |
GO:0007165 | signal transduction | 3.98e-01 | 1.00e+00 | 0.402 | 3 | 8 | 950 |
GO:0005524 | ATP binding | 4.08e-01 | 1.00e+00 | 0.306 | 4 | 13 | 1354 |
GO:0006184 | GTP catabolic process | 4.11e-01 | 1.00e+00 | 0.928 | 1 | 2 | 220 |
GO:0005622 | intracellular | 4.20e-01 | 1.00e+00 | 0.889 | 1 | 2 | 226 |
GO:0019221 | cytokine-mediated signaling pathway | 4.25e-01 | 1.00e+00 | 0.864 | 1 | 3 | 230 |
GO:0007399 | nervous system development | 4.46e-01 | 1.00e+00 | 0.772 | 1 | 3 | 245 |
GO:0046872 | metal ion binding | 4.69e-01 | 1.00e+00 | 0.192 | 4 | 6 | 1465 |
GO:0008270 | zinc ion binding | 4.74e-01 | 1.00e+00 | 0.235 | 3 | 11 | 1067 |
GO:0005975 | carbohydrate metabolic process | 4.84e-01 | 1.00e+00 | 0.611 | 1 | 3 | 274 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 4.85e-01 | 1.00e+00 | 0.606 | 1 | 4 | 275 |
GO:0007283 | spermatogenesis | 4.86e-01 | 1.00e+00 | 0.601 | 1 | 1 | 276 |
GO:0019899 | enzyme binding | 5.01e-01 | 1.00e+00 | 0.539 | 1 | 3 | 288 |
GO:0006954 | inflammatory response | 5.02e-01 | 1.00e+00 | 0.534 | 1 | 1 | 289 |
GO:0005743 | mitochondrial inner membrane | 5.15e-01 | 1.00e+00 | 0.480 | 1 | 3 | 300 |
GO:0043234 | protein complex | 5.15e-01 | 1.00e+00 | 0.480 | 1 | 4 | 300 |
GO:0005856 | cytoskeleton | 5.28e-01 | 1.00e+00 | 0.428 | 1 | 2 | 311 |
GO:0019901 | protein kinase binding | 5.38e-01 | 1.00e+00 | 0.387 | 1 | 4 | 320 |
GO:0003682 | chromatin binding | 5.54e-01 | 1.00e+00 | 0.325 | 1 | 7 | 334 |
GO:0007275 | multicellular organismal development | 5.65e-01 | 1.00e+00 | 0.283 | 1 | 1 | 344 |
GO:0046982 | protein heterodimerization activity | 6.20e-01 | 1.00e+00 | 0.069 | 1 | 3 | 399 |
GO:0006508 | proteolysis | 6.30e-01 | 1.00e+00 | 0.030 | 1 | 2 | 410 |
GO:0009986 | cell surface | 6.40e-01 | 1.00e+00 | -0.012 | 1 | 4 | 422 |
GO:0048471 | perinuclear region of cytoplasm | 7.20e-01 | 1.00e+00 | -0.322 | 1 | 1 | 523 |
GO:0006915 | apoptotic process | 7.51e-01 | 1.00e+00 | -0.448 | 1 | 8 | 571 |
GO:0005783 | endoplasmic reticulum | 7.74e-01 | 1.00e+00 | -0.544 | 1 | 2 | 610 |
GO:0042803 | protein homodimerization activity | 7.78e-01 | 1.00e+00 | -0.560 | 1 | 6 | 617 |
GO:0005887 | integral component of plasma membrane | 9.06e-01 | 1.00e+00 | -1.199 | 1 | 1 | 961 |
GO:0005615 | extracellular space | 9.17e-01 | 1.00e+00 | -1.271 | 1 | 4 | 1010 |
GO:0044281 | small molecule metabolic process | 9.60e-01 | 1.00e+00 | -1.630 | 1 | 12 | 1295 |
GO:0016021 | integral component of membrane | 9.87e-01 | 1.00e+00 | -1.569 | 2 | 7 | 2483 |
GO:0070062 | extracellular vesicular exosome | 9.88e-01 | 1.00e+00 | -1.588 | 2 | 15 | 2516 |
GO:0005886 | plasma membrane | 9.95e-01 | 1.00e+00 | -1.760 | 2 | 14 | 2834 |