meta-reg-snw-80153

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-1029 chia-screen-data-Fav 2.959 7.22e-17 1.01e-04 1.12e-03 11 10
reg-snw-80153 chia-screen-data-Fav 2.203 2.78e-07 4.60e-02 3.49e-02 32 22
chia-screen-data-Fav-meta-reg-snw-80153 subnetwork

Genes (39)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Chia-Hits Primary Chia-Hits Secondary
CNOT1 23019 7-2.3472.263124Yes-
CHERP 10523 2-1.6322.203210--
RAE1 8480 2-1.5012.342204--
PHB 5245 12-2.7432.689163YesYes
RASSF7 8045 2-1.5182.20349--
VARS 7407 8-2.3662.689204Yes-
POU5F1 5460 12-5.1483.538179YesYes
FBXO22 26263 8-1.7392.459208--
EDC3 80153 2-0.9432.20342--
E4F1 1877 3-2.3702.95927YesYes
RNF40 9810 2-2.0822.49263Yes-
EIF2S2 8894 9-2.9992.459103YesYes
FBXL6 26233 5-2.2532.68922Yes-
SUV39H2 79723 7-2.3072.41021YesYes
BEST1 7439 2-2.2502.28119Yes-
KLC3 147700 2-2.1302.290132Yes-
ETF1 2107 7-2.8292.50377YesYes
CCT7 10574 10-2.3352.459173Yes-
CPSF3 51692 7-2.6862.50331YesYes
HNRNPU 3192 12-2.8692.644172Yes-
DRG2 1819 2-2.5262.49211Yes-
GTF3C2 2976 2-1.2302.225179--
NDUFA4L2 56901 10-2.4772.45921Yes-
NONO 4841 2-1.2322.203223--
TMEM68 137695 2-1.5652.31297--
WDR18 57418 2-1.3212.225213--
YAP1 10413 12-4.2563.53853Yes-
NCBP1 4686 8-2.5102.45984YesYes
SYNCRIP 10492 8-2.4012.503247YesYes
FTSJ1 24140 5-2.4632.689130YesYes
LCE1E 353135 2-2.4282.41431YesYes
GSPT1 2935 7-2.3132.50347YesYes
NFRKB 4798 3-3.1293.10833YesYes
YY1 7528 3-2.5723.120168YesYes
GPS1 2873 10-3.6212.68962YesYes
NOLC1 9221 5-1.9852.503136--
POLH 5429 8-2.5862.45924YesYes
DDIT3 1649 11-2.8253.504343YesYes
CDKN2A 1029 3-1.7742.959126--

Interactions (78)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RAE1 8480 FBXL6 26233 pd > reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
CHERP 10523 KLC3 147700 pd <> reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
RASSF7 8045 EDC3 80153 pd > reg.ITFP.txt: no annot
ETF1 2107 GSPT1 2935 pp -- int.I2D: MINT, BCI, BioGrid, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
CDKN2A 1029 HNRNPU 3192 pp -- int.Intact: MI:0915(physical association)
GTF3C2 2976 EDC3 80153 pd > reg.ITFP.txt: no annot
WDR18 57418 EDC3 80153 pd > reg.ITFP.txt: no annot
VARS 7407 WDR18 57418 pd <> reg.ITFP.txt: no annot
NOLC1 9221 WDR18 57418 pd <> reg.ITFP.txt: no annot
SUV39H2 79723 TMEM68 137695 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
GTF3C2 2976 NOLC1 9221 pd <> reg.ITFP.txt: no annot
RAE1 8480 EDC3 80153 pd > reg.ITFP.txt: no annot
DDIT3 1649 NONO 4841 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
NFRKB 4798 NONO 4841 pd < reg.ITFP.txt: no annot
NFRKB 4798 YY1 7528 pp -- int.I2D: BioGrid
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
CDKN2A 1029 FTSJ1 24140 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
RAE1 8480 NOLC1 9221 pd <> reg.ITFP.txt: no annot
RNF40 9810 EDC3 80153 pd > reg.ITFP.txt: no annot
CDKN2A 1029 GSPT1 2935 pp -- int.I2D: BCI;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
DRG2 1819 GTF3C2 2976 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 WDR18 57418 pd <> reg.ITFP.txt: no annot
FBXO22 26263 WDR18 57418 pd <> reg.ITFP.txt: no annot
FBXO22 26263 EDC3 80153 pd > reg.ITFP.txt: no annot
DDIT3 1649 HNRNPU 3192 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
NONO 4841 FTSJ1 24140 pd > reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
KLC3 147700 LCE1E 353135 pd > reg.ITFP.txt: no annot
DRG2 1819 NONO 4841 pd < reg.ITFP.txt: no annot
CHERP 10523 LCE1E 353135 pd > reg.ITFP.txt: no annot
DDIT3 1649 VARS 7407 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
NONO 4841 EDC3 80153 pd > reg.ITFP.txt: no annot
NFRKB 4798 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
ETF1 2107 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, YeastLow
GTF3C2 2976 WDR18 57418 pd <> reg.ITFP.txt: no annot
GTF3C2 2976 RAE1 8480 pd <> reg.ITFP.txt: no annot
CPSF3 51692 TMEM68 137695 pd < reg.ITFP.txt: no annot
RNF40 9810 KLC3 147700 pd <> reg.ITFP.txt: no annot
EDC3 80153 KLC3 147700 pd < reg.ITFP.txt: no annot
FBXL6 26233 WDR18 57418 pd < reg.ITFP.txt: no annot
BEST1 7439 CHERP 10523 pd < reg.ITFP.txt: no annot
CDKN2A 1029 E4F1 1877 pp -- int.I2D: BioGrid;
int.HPRD: in vivo
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot
CHERP 10523 EDC3 80153 pd > reg.ITFP.txt: no annot
GTF3C2 2976 NONO 4841 pd <> reg.ITFP.txt: no annot
GPS1 2873 WDR18 57418 pd <> reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
RASSF7 8045 CHERP 10523 pd <> reg.ITFP.txt: no annot
HNRNPU 3192 NONO 4841 pd < reg.ITFP.txt: no annot
NONO 4841 RAE1 8480 pd <> reg.ITFP.txt: no annot
NCBP1 4686 RNF40 9810 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, VidalHuman_core;
int.HPRD: yeast 2-hybrid
PHB 5245 WDR18 57418 pd < reg.ITFP.txt: no annot
CDKN2A 1029 YY1 7528 pd < reg.TRANSFAC.txt: no annot
CDKN2A 1029 YY1 7528 pp -- int.I2D: BioGrid, BIND, BCI
RASSF7 8045 KLC3 147700 pd <> reg.ITFP.txt: no annot
GTF3C2 2976 CNOT1 23019 pd > reg.ITFP.txt: no annot
EDC3 80153 TMEM68 137695 pd < reg.ITFP.txt: no annot
RAE1 8480 CPSF3 51692 pd > reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
GSPT1 2935 NOLC1 9221 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 SYNCRIP 10492 pp -- int.Mint: MI:0915(physical association)
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
RAE1 8480 WDR18 57418 pd <> reg.ITFP.txt: no annot
NOLC1 9221 EDC3 80153 pd > reg.ITFP.txt: no annot
NONO 4841 FBXO22 26263 pd <> reg.ITFP.txt: no annot
FTSJ1 24140 WDR18 57418 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
CCT7 10574 WDR18 57418 pd < reg.ITFP.txt: no annot

Related GO terms (369)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0003723RNA binding1.17e-071.92e-033.407915355
GO:0005654nucleoplasm8.17e-071.33e-022.31313311095
GO:0010467gene expression2.71e-064.42e-022.6451027669
GO:0044822poly(A) RNA binding4.78e-067.80e-022.22012271078
GO:0003747translation release factor activity3.33e-055.43e-017.709224
GO:0044212transcription regulatory region DNA binding5.14e-058.39e-013.61355171
GO:0070934CRD-mediated mRNA stabilization5.54e-059.04e-017.387225
GO:0070937CRD-mediated mRNA stability complex8.30e-051.00e+007.124226
GO:0030529ribonucleoprotein complex1.54e-041.00e+003.87646114
GO:0005515protein binding2.11e-041.00e+000.82926776127
GO:0008380RNA splicing2.16e-041.00e+003.173514232
GO:0006379mRNA cleavage2.47e-041.00e+006.3872210
GO:0010225response to UV-C2.47e-041.00e+006.3872210
GO:0006396RNA processing3.93e-041.00e+004.3873460
GO:0042789mRNA transcription from RNA polymerase II promoter4.27e-041.00e+006.0092213
GO:0006406mRNA export from nucleus4.33e-041.00e+004.3403562
GO:0031011Ino80 complex4.97e-041.00e+005.9022214
GO:0006479protein methylation5.73e-041.00e+005.8022215
GO:0000398mRNA splicing, via spliceosome6.29e-041.00e+003.34349165
GO:0003714transcription corepressor activity8.53e-041.00e+003.22545179
GO:0001649osteoblast differentiation1.50e-031.00e+003.7243395
GO:0031047gene silencing by RNA1.74e-031.00e+005.0092226
GO:0051209release of sequestered calcium ion into cytosol1.74e-031.00e+005.0092226
GO:0016071mRNA metabolic process1.92e-031.00e+002.90848223
GO:0002128tRNA nucleoside ribose methylation2.39e-031.00e+008.709111
GO:2000016negative regulation of determination of dorsal identity2.39e-031.00e+008.709111
GO:0090308regulation of methylation-dependent chromatin silencing2.39e-031.00e+008.709111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway2.39e-031.00e+008.709111
GO:0060795cell fate commitment involved in formation of primary germ layer2.39e-031.00e+008.709111
GO:0008079translation termination factor activity2.39e-031.00e+008.709111
GO:0009794regulation of mitotic cell cycle, embryonic2.39e-031.00e+008.709111
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.53e-031.00e+003.46133114
GO:0016070RNA metabolic process2.78e-031.00e+002.76148247
GO:0045892negative regulation of transcription, DNA-templated3.21e-031.00e+002.30357424
GO:0031124mRNA 3'-end processing4.51e-031.00e+004.3172442
GO:0004832valine-tRNA ligase activity4.77e-031.00e+007.709112
GO:0060242contact inhibition4.77e-031.00e+007.709112
GO:0006403RNA localization4.77e-031.00e+007.709112
GO:0008175tRNA methyltransferase activity4.77e-031.00e+007.709112
GO:0005846nuclear cap binding complex4.77e-031.00e+007.709112
GO:0002176male germ cell proliferation4.77e-031.00e+007.709112
GO:0006438valyl-tRNA aminoacylation4.77e-031.00e+007.709112
GO:0009786regulation of asymmetric cell division4.77e-031.00e+007.709112
GO:0055105ubiquitin-protein transferase inhibitor activity4.77e-031.00e+007.709112
GO:0060965negative regulation of gene silencing by miRNA4.77e-031.00e+007.709112
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress4.77e-031.00e+007.709112
GO:0034696response to prostaglandin F4.77e-031.00e+007.709112
GO:0044324regulation of transcription involved in anterior/posterior axis specification4.77e-031.00e+007.709112
GO:0006369termination of RNA polymerase II transcription5.16e-031.00e+004.2172445
GO:0006974cellular response to DNA damage stimulus6.30e-031.00e+002.99034158
GO:0005737cytoplasm6.51e-031.00e+000.83917433976
GO:0016020membrane6.65e-031.00e+001.26110271746
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay7.10e-031.00e+003.9812253
GO:0036123histone H3-K9 dimethylation7.15e-031.00e+007.124113
GO:0035986senescence-associated heterochromatin focus assembly7.15e-031.00e+007.124113
GO:2000111positive regulation of macrophage apoptotic process7.15e-031.00e+007.124113
GO:0005850eukaryotic translation initiation factor 2 complex7.15e-031.00e+007.124123
GO:0016149translation release factor activity, codon specific7.15e-031.00e+007.124113
GO:0035985senescence-associated heterochromatin focus7.15e-031.00e+007.124113
GO:0003130BMP signaling pathway involved in heart induction7.15e-031.00e+007.124113
GO:0000932cytoplasmic mRNA processing body7.90e-031.00e+003.9022256
GO:2000774positive regulation of cellular senescence9.52e-031.00e+006.709114
GO:0097452GAIT complex9.52e-031.00e+006.709124
GO:0051533positive regulation of NFAT protein import into nucleus9.52e-031.00e+006.709114
GO:0060913cardiac cell fate determination9.52e-031.00e+006.709114
GO:0007000nucleolus organization9.52e-031.00e+006.709114
GO:0033503HULC complex9.52e-031.00e+006.709114
GO:1903377negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway9.52e-031.00e+006.709114
GO:0006290pyrimidine dimer repair9.52e-031.00e+006.709114
GO:0033088negative regulation of immature T cell proliferation in thymus9.52e-031.00e+006.709114
GO:0006310DNA recombination1.12e-021.00e+003.6432267
GO:0001714endodermal cell fate specification1.19e-021.00e+006.387115
GO:0043620regulation of DNA-templated transcription in response to stress1.19e-021.00e+006.387115
GO:1902510regulation of apoptotic DNA fragmentation1.19e-021.00e+006.387115
GO:0030321transepithelial chloride transport1.19e-021.00e+006.387115
GO:0034393positive regulation of smooth muscle cell apoptotic process1.19e-021.00e+006.387115
GO:0010606positive regulation of cytoplasmic mRNA processing body assembly1.19e-021.00e+006.387115
GO:0097371MDM2/MDM4 family protein binding1.19e-021.00e+006.387115
GO:0048742regulation of skeletal muscle fiber development1.19e-021.00e+006.387115
GO:0006398histone mRNA 3'-end processing1.19e-021.00e+006.387115
GO:0045292mRNA cis splicing, via spliceosome1.19e-021.00e+006.387115
GO:0031442positive regulation of mRNA 3'-end processing1.19e-021.00e+006.387115
GO:0006449regulation of translational termination1.19e-021.00e+006.387115
GO:0036124histone H3-K9 trimethylation1.19e-021.00e+006.387115
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.26e-021.00e+001.829510589
GO:0003677DNA binding1.31e-021.00e+001.3098161351
GO:0005829cytosol1.36e-021.00e+000.97112382562
GO:0042797tRNA transcription from RNA polymerase III promoter1.43e-021.00e+006.124126
GO:0010564regulation of cell cycle process1.43e-021.00e+006.124116
GO:0050847progesterone receptor signaling pathway1.43e-021.00e+006.124116
GO:0002181cytoplasmic translation1.43e-021.00e+006.124116
GO:0046974histone methyltransferase activity (H3-K9 specific)1.43e-021.00e+006.124116
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.43e-021.00e+006.124116
GO:0000127transcription factor TFIIIC complex1.43e-021.00e+006.124126
GO:00427915S class rRNA transcription from RNA polymerase III type 1 promoter1.43e-021.00e+006.124126
GO:0006333chromatin assembly or disassembly1.43e-021.00e+006.124116
GO:0071204histone pre-mRNA 3'end processing complex1.43e-021.00e+006.124116
GO:0035497cAMP response element binding1.43e-021.00e+006.124116
GO:0042382paraspeckles1.43e-021.00e+006.124126
GO:0071013catalytic step 2 spliceosome1.53e-021.00e+003.4052379
GO:0046825regulation of protein export from nucleus1.66e-021.00e+005.902127
GO:0002161aminoacyl-tRNA editing activity1.66e-021.00e+005.902117
GO:0004521endoribonuclease activity1.66e-021.00e+005.902117
GO:0006301postreplication repair1.66e-021.00e+005.902117
GO:0051444negative regulation of ubiquitin-protein transferase activity1.66e-021.00e+005.902117
GO:0006282regulation of DNA repair1.66e-021.00e+005.902117
GO:0006366transcription from RNA polymerase II promoter1.82e-021.00e+001.978414425
GO:0006415translational termination1.83e-021.00e+003.2662287
GO:0042754negative regulation of circadian rhythm1.90e-021.00e+005.709118
GO:0001955blood vessel maturation1.90e-021.00e+005.709118
GO:0000339RNA cap binding1.90e-021.00e+005.709118
GO:0033523histone H2B ubiquitination1.90e-021.00e+005.709118
GO:0003713transcription coactivator activity1.92e-021.00e+002.39337239
GO:0016363nuclear matrix2.03e-021.00e+003.1852592
GO:0008134transcription factor binding2.07e-021.00e+002.35136246
GO:0071354cellular response to interleukin-62.13e-021.00e+005.539119
GO:00084095'-3' exonuclease activity2.13e-021.00e+005.539119
GO:0048103somatic stem cell division2.13e-021.00e+005.539119
GO:0010388cullin deneddylation2.13e-021.00e+005.539159
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.13e-021.00e+005.539119
GO:0035253ciliary rootlet2.13e-021.00e+005.539119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.13e-021.00e+005.539119
GO:0006983ER overload response2.13e-021.00e+005.539119
GO:0000400four-way junction DNA binding2.13e-021.00e+005.539119
GO:0005832chaperonin-containing T-complex2.13e-021.00e+005.539119
GO:0006364rRNA processing2.20e-021.00e+003.1242296
GO:0004842ubiquitin-protein transferase activity2.30e-021.00e+002.29435256
GO:0002199zona pellucida receptor complex2.36e-021.00e+005.3871110
GO:0006450regulation of translational fidelity2.36e-021.00e+005.3871110
GO:0008088axon cargo transport2.36e-021.00e+005.3871110
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay2.36e-021.00e+005.3871110
GO:0090399replicative senescence2.36e-021.00e+005.3871110
GO:0000731DNA synthesis involved in DNA repair2.36e-021.00e+005.3871110
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway2.36e-021.00e+005.3871210
GO:0010944negative regulation of transcription by competitive promoter binding2.36e-021.00e+005.3871110
GO:0006281DNA repair2.49e-021.00e+002.25034264
GO:0005845mRNA cap binding complex2.60e-021.00e+005.2501111
GO:0048387negative regulation of retinoic acid receptor signaling pathway2.60e-021.00e+005.2501111
GO:0071850mitotic cell cycle arrest2.60e-021.00e+005.2501111
GO:0045662negative regulation of myoblast differentiation2.60e-021.00e+005.2501111
GO:0010390histone monoubiquitination2.60e-021.00e+005.2501111
GO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening2.60e-021.00e+005.2501111
GO:0033235positive regulation of protein sumoylation2.60e-021.00e+005.2501111
GO:0035413positive regulation of catenin import into nucleus2.60e-021.00e+005.2501111
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.60e-021.00e+005.2501111
GO:0004535poly(A)-specific ribonuclease activity2.60e-021.00e+005.2501111
GO:2000036regulation of stem cell maintenance2.60e-021.00e+005.2501111
GO:0060391positive regulation of SMAD protein import into nucleus2.60e-021.00e+005.2501111
GO:0008334histone mRNA metabolic process2.83e-021.00e+005.1241112
GO:0043517positive regulation of DNA damage response, signal transduction by p53 class mediator2.83e-021.00e+005.1241112
GO:0001953negative regulation of cell-matrix adhesion2.83e-021.00e+005.1241112
GO:0008143poly(A) binding2.83e-021.00e+005.1241212
GO:0004861cyclin-dependent protein serine/threonine kinase inhibitor activity2.83e-021.00e+005.1241112
GO:0044267cellular protein metabolic process2.98e-021.00e+001.75847495
GO:0030308negative regulation of cell growth2.98e-021.00e+002.88922113
GO:0007140male meiosis3.06e-021.00e+005.0091113
GO:0042974retinoic acid receptor binding3.06e-021.00e+005.0091113
GO:0060766negative regulation of androgen receptor signaling pathway3.06e-021.00e+005.0091113
GO:0035198miRNA binding3.06e-021.00e+005.0091113
GO:0000209protein polyubiquitination3.13e-021.00e+002.85125116
GO:0071480cellular response to gamma radiation3.30e-021.00e+004.9021114
GO:0005095GTPase inhibitor activity3.30e-021.00e+004.9021114
GO:0030889negative regulation of B cell proliferation3.30e-021.00e+004.9021114
GO:0050908detection of light stimulus involved in visual perception3.53e-021.00e+004.8021115
GO:0001824blastocyst development3.53e-021.00e+004.8021115
GO:0030014CCR4-NOT complex3.53e-021.00e+004.8021115
GO:0006260DNA replication3.59e-021.00e+002.74324125
GO:0005739mitochondrion3.63e-021.00e+001.2636161046
GO:0007050cell cycle arrest3.64e-021.00e+002.73223126
GO:0006511ubiquitin-dependent protein catabolic process3.69e-021.00e+002.72023127
GO:0016746transferase activity, transferring acyl groups3.76e-021.00e+004.7091216
GO:0051276chromosome organization3.76e-021.00e+004.7091216
GO:0016032viral process3.91e-021.00e+001.632416540
GO:0001829trophectodermal cell differentiation3.99e-021.00e+004.6221217
GO:0048593camera-type eye morphogenesis3.99e-021.00e+004.6221117
GO:0005730nucleolus4.27e-021.00e+000.9918281684
GO:0005525GTP binding4.32e-021.00e+001.93635328
GO:0005634nucleus4.40e-021.00e+000.55917554828
GO:0017075syntaxin-1 binding4.45e-021.00e+004.4611119
GO:0071158positive regulation of cell cycle arrest4.45e-021.00e+004.4611119
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity4.45e-021.00e+004.4611219
GO:0090398cellular senescence4.67e-021.00e+004.3871120
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription4.67e-021.00e+004.3871120
GO:0032757positive regulation of interleukin-8 production4.90e-021.00e+004.3171121
GO:0031648protein destabilization4.90e-021.00e+004.3171221
GO:0042326negative regulation of phosphorylation4.90e-021.00e+004.3171121
GO:0016575histone deacetylation4.90e-021.00e+004.3171121
GO:0008637apoptotic mitochondrial changes4.90e-021.00e+004.3171121
GO:0008017microtubule binding4.98e-021.00e+002.48024150
GO:0000082G1/S transition of mitotic cell cycle4.98e-021.00e+002.48024150
GO:0051924regulation of calcium ion transport5.13e-021.00e+004.2501122
GO:0005720nuclear heterochromatin5.13e-021.00e+004.2501122
GO:0006378mRNA polyadenylation5.13e-021.00e+004.2501222
GO:0036464cytoplasmic ribonucleoprotein granule5.13e-021.00e+004.2501122
GO:0071346cellular response to interferon-gamma5.36e-021.00e+004.1851223
GO:0034660ncRNA metabolic process5.36e-021.00e+004.1851123
GO:0005640nuclear outer membrane5.36e-021.00e+004.1851123
GO:0008135translation factor activity, nucleic acid binding5.58e-021.00e+004.1241224
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress5.58e-021.00e+004.1241124
GO:0043005neuron projection5.65e-021.00e+002.37824161
GO:0008285negative regulation of cell proliferation5.68e-021.00e+001.77434367
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening5.81e-021.00e+004.0651125
GO:0031519PcG protein complex5.81e-021.00e+004.0651125
GO:0051059NF-kappaB binding5.81e-021.00e+004.0651225
GO:0035329hippo signaling6.04e-021.00e+004.0091126
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic6.04e-021.00e+004.0091126
GO:0031424keratinization6.26e-021.00e+003.9541127
GO:0006913nucleocytoplasmic transport6.26e-021.00e+003.9541127
GO:0000188inactivation of MAPK activity6.26e-021.00e+003.9541127
GO:0030331estrogen receptor binding6.26e-021.00e+003.9541227
GO:0000387spliceosomal snRNP assembly6.26e-021.00e+003.9541127
GO:0007339binding of sperm to zona pellucida6.26e-021.00e+003.9541127
GO:0000976transcription regulatory region sequence-specific DNA binding6.48e-021.00e+003.9021128
GO:0043022ribosome binding6.48e-021.00e+003.9021228
GO:0033017sarcoplasmic reticulum membrane6.48e-021.00e+003.9021128
GO:0019894kinesin binding6.48e-021.00e+003.9021128
GO:0007049cell cycle6.67e-021.00e+002.24124177
GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay6.71e-021.00e+003.8511129
GO:0003887DNA-directed DNA polymerase activity6.71e-021.00e+003.8511129
GO:0071897DNA biosynthetic process6.71e-021.00e+003.8511129
GO:0005667transcription factor complex6.74e-021.00e+002.23323178
GO:0031625ubiquitin protein ligase binding6.87e-021.00e+002.21722180
GO:00063707-methylguanosine mRNA capping6.93e-021.00e+003.8021230
GO:0031647regulation of protein stability6.93e-021.00e+003.8021230
GO:0010827regulation of glucose transport7.15e-021.00e+003.7551331
GO:0016604nuclear body7.15e-021.00e+003.7551131
GO:0070534protein K63-linked ubiquitination7.15e-021.00e+003.7551131
GO:0042594response to starvation7.38e-021.00e+003.7091332
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic7.38e-021.00e+003.7091132
GO:0034644cellular response to UV7.38e-021.00e+003.7091132
GO:1903507negative regulation of nucleic acid-templated transcription7.38e-021.00e+003.7091132
GO:0008180COP9 signalosome7.82e-021.00e+003.6221634
GO:0006351transcription, DNA-templated7.89e-021.00e+000.8867171585
GO:0009267cellular response to starvation8.26e-021.00e+003.5391136
GO:0006446regulation of translational initiation8.26e-021.00e+003.5391236
GO:0007077mitotic nuclear envelope disassembly8.48e-021.00e+003.5001337
GO:0006821chloride transport8.48e-021.00e+003.5001137
GO:0051084'de novo' posttranslational protein folding8.48e-021.00e+003.5001137
GO:0042752regulation of circadian rhythm8.48e-021.00e+003.5001337
GO:0006383transcription from RNA polymerase III promoter8.92e-021.00e+003.4241339
GO:0071407cellular response to organic cyclic compound8.92e-021.00e+003.4241339
GO:0035019somatic stem cell maintenance9.14e-021.00e+003.3871240
GO:0034707chloride channel complex9.14e-021.00e+003.3871140
GO:0005254chloride channel activity9.35e-021.00e+003.3511141
GO:0017148negative regulation of translation9.35e-021.00e+003.3511341
GO:0006418tRNA aminoacylation for protein translation9.57e-021.00e+003.3171342
GO:0008645hexose transport9.57e-021.00e+003.3171342
GO:0031514motile cilium9.57e-021.00e+003.3171142
GO:0016874ligase activity9.99e-021.00e+001.90224224
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.00e-011.00e+003.2501144
GO:0005871kinesin complex1.00e-011.00e+003.2501144
GO:0050434positive regulation of viral transcription1.00e-011.00e+003.2501244
GO:0015030Cajal body1.02e-011.00e+003.2171145
GO:0003700sequence-specific DNA binding transcription factor activity1.02e-011.00e+001.162410748
GO:0001047core promoter binding1.04e-011.00e+003.1851246
GO:0044297cell body1.04e-011.00e+003.1851146
GO:0043525positive regulation of neuron apoptotic process1.04e-011.00e+003.1851246
GO:0007067mitotic nuclear division1.05e-011.00e+001.85724231
GO:0048511rhythmic process1.06e-011.00e+003.1541247
GO:0006412translation1.08e-011.00e+001.83325235
GO:0045893positive regulation of transcription, DNA-templated1.10e-011.00e+001.36636487
GO:0003743translation initiation factor activity1.11e-011.00e+003.0941549
GO:0042802identical protein binding1.12e-011.00e+001.35436491
GO:0005778peroxisomal membrane1.13e-011.00e+003.0651250
GO:0006986response to unfolded protein1.15e-011.00e+003.0371251
GO:0040008regulation of growth1.15e-011.00e+003.0371151
GO:0007254JNK cascade1.15e-011.00e+003.0371251
GO:0003684damaged DNA binding1.15e-011.00e+003.0371151
GO:0000775chromosome, centromeric region1.17e-011.00e+003.0091352
GO:0034976response to endoplasmic reticulum stress1.17e-011.00e+003.0091152
GO:0045454cell redox homeostasis1.17e-011.00e+003.0091152
GO:0009611response to wounding1.19e-011.00e+002.9811153
GO:0007623circadian rhythm1.21e-011.00e+002.9541254
GO:0006355regulation of transcription, DNA-templated1.21e-011.00e+000.9225131104
GO:0002039p53 binding1.23e-011.00e+002.9281355
GO:0005874microtubule1.26e-011.00e+001.69823258
GO:0000724double-strand break repair via homologous recombination1.28e-011.00e+002.8761157
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.32e-011.00e+002.8261259
GO:0015758glucose transport1.32e-011.00e+002.8261359
GO:0005643nuclear pore1.32e-011.00e+002.8261359
GO:0003777microtubule motor activity1.34e-011.00e+002.8021160
GO:0000166nucleotide binding1.37e-011.00e+001.62226272
GO:0006987activation of signaling protein activity involved in unfolded protein response1.38e-011.00e+002.7551262
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.38e-011.00e+002.7551162
GO:0000151ubiquitin ligase complex1.40e-011.00e+002.7321263
GO:0006417regulation of translation1.40e-011.00e+002.7321163
GO:0032088negative regulation of NF-kappaB transcription factor activity1.42e-011.00e+002.7091264
GO:0006469negative regulation of protein kinase activity1.44e-011.00e+002.6871265
GO:0006368transcription elongation from RNA polymerase II promoter1.48e-011.00e+002.6431367
GO:0006338chromatin remodeling1.50e-011.00e+002.6221168
GO:1902476chloride transmembrane transport1.54e-011.00e+002.5801170
GO:0010468regulation of gene expression1.59e-011.00e+002.5391172
GO:0016567protein ubiquitination1.60e-011.00e+001.48525299
GO:0000785chromatin1.61e-011.00e+002.5191273
GO:0008152metabolic process1.62e-011.00e+001.47122302
GO:0002020protease binding1.63e-011.00e+002.5001174
GO:0042826histone deacetylase binding1.63e-011.00e+002.5001274
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding1.65e-011.00e+002.4801175
GO:0007265Ras protein signal transduction1.65e-011.00e+002.4801275
GO:0006874cellular calcium ion homeostasis1.67e-011.00e+002.4611176
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.67e-011.00e+002.4611276
GO:0044325ion channel binding1.69e-011.00e+002.4421177
GO:0008584male gonad development1.69e-011.00e+002.4421177
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.69e-011.00e+002.4421277
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity1.69e-011.00e+002.4421277
GO:0030968endoplasmic reticulum unfolded protein response1.77e-011.00e+002.3691281
GO:0030154cell differentiation1.82e-011.00e+001.36522325
GO:0009952anterior/posterior pattern specification1.82e-011.00e+002.3171284
GO:0008283cell proliferation1.87e-011.00e+001.33823331
GO:0009653anatomical structure morphogenesis1.88e-011.00e+002.2661187
GO:0090090negative regulation of canonical Wnt signaling pathway1.90e-011.00e+002.2501488
GO:0006464cellular protein modification process1.92e-011.00e+002.2331189
GO:0050821protein stabilization1.96e-011.00e+002.2011391
GO:0005770late endosome2.02e-011.00e+002.1541194
GO:0051082unfolded protein binding2.04e-011.00e+002.1391395
GO:0030018Z disc2.10e-011.00e+002.0941298
GO:0071456cellular response to hypoxia2.10e-011.00e+002.0941298
GO:0043565sequence-specific DNA binding2.17e-011.00e+001.19723365
GO:0005815microtubule organizing center2.32e-011.00e+001.92811110
GO:0005819spindle2.39e-011.00e+001.87612114
GO:0005635nuclear envelope2.43e-011.00e+001.85113116
GO:0000278mitotic cell cycle2.46e-011.00e+001.072212398
GO:0006413translational initiation2.70e-011.00e+001.67614131
GO:0016055Wnt signaling pathway2.87e-011.00e+001.56913141
GO:0006457protein folding3.01e-011.00e+001.49011149
GO:0016323basolateral plasma membrane3.01e-011.00e+001.49011149
GO:0042981regulation of apoptotic process3.04e-011.00e+001.47113151
GO:0045944positive regulation of transcription from RNA polymerase II promoter3.06e-011.00e+000.630313811
GO:0034220ion transmembrane transport3.31e-011.00e+001.32511167
GO:0007601visual perception3.32e-011.00e+001.31711168
GO:0006397mRNA processing3.34e-011.00e+001.30816169
GO:0016607nuclear speck3.44e-011.00e+001.25816175
GO:0055085transmembrane transport3.49e-011.00e+000.70325514
GO:0006367transcription initiation from RNA polymerase II promoter3.58e-011.00e+001.18515184
GO:0032403protein complex binding3.59e-011.00e+001.17812185
GO:0003924GTPase activity3.87e-011.00e+001.04412203
GO:0001701in utero embryonic development3.97e-011.00e+000.99512210
GO:0007165signal transduction3.98e-011.00e+000.40238950
GO:0005524ATP binding4.08e-011.00e+000.3064131354
GO:0006184GTP catabolic process4.11e-011.00e+000.92812220
GO:0005622intracellular4.20e-011.00e+000.88912226
GO:0019221cytokine-mediated signaling pathway4.25e-011.00e+000.86413230
GO:0007399nervous system development4.46e-011.00e+000.77213245
GO:0046872metal ion binding4.69e-011.00e+000.192461465
GO:0008270zinc ion binding4.74e-011.00e+000.2353111067
GO:0005975carbohydrate metabolic process4.84e-011.00e+000.61113274
GO:0006357regulation of transcription from RNA polymerase II promoter4.85e-011.00e+000.60614275
GO:0007283spermatogenesis4.86e-011.00e+000.60111276
GO:0019899enzyme binding5.01e-011.00e+000.53913288
GO:0006954inflammatory response5.02e-011.00e+000.53411289
GO:0005743mitochondrial inner membrane5.15e-011.00e+000.48013300
GO:0043234protein complex5.15e-011.00e+000.48014300
GO:0005856cytoskeleton5.28e-011.00e+000.42812311
GO:0019901protein kinase binding5.38e-011.00e+000.38714320
GO:0003682chromatin binding5.54e-011.00e+000.32517334
GO:0007275multicellular organismal development5.65e-011.00e+000.28311344
GO:0046982protein heterodimerization activity6.20e-011.00e+000.06913399
GO:0006508proteolysis6.30e-011.00e+000.03012410
GO:0009986cell surface6.40e-011.00e+00-0.01214422
GO:0048471perinuclear region of cytoplasm7.20e-011.00e+00-0.32211523
GO:0006915apoptotic process7.51e-011.00e+00-0.44818571
GO:0005783endoplasmic reticulum7.74e-011.00e+00-0.54412610
GO:0042803protein homodimerization activity7.78e-011.00e+00-0.56016617
GO:0005887integral component of plasma membrane9.06e-011.00e+00-1.19911961
GO:0005615extracellular space9.17e-011.00e+00-1.271141010
GO:0044281small molecule metabolic process9.60e-011.00e+00-1.6301121295
GO:0016021integral component of membrane9.87e-011.00e+00-1.569272483
GO:0070062extracellular vesicular exosome9.88e-011.00e+00-1.5882152516
GO:0005886plasma membrane9.95e-011.00e+00-1.7602142834