Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-8562 | chia-screen-data-Fav | 2.263 | 1.35e-07 | 3.15e-02 | 2.44e-02 | 32 | 24 |
int-snw-892 | chia-screen-data-Fav | 2.968 | 5.68e-17 | 8.94e-05 | 1.03e-03 | 17 | 15 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
CCNC | 892 | 2 | -1.726 | 2.968 | 101 | - | - |
ANAPC5 | 51433 | 6 | -1.264 | 2.263 | 239 | - | - |
CNOT1 | 23019 | 7 | -2.347 | 2.263 | 124 | Yes | - |
PHB | 5245 | 12 | -2.743 | 2.689 | 163 | Yes | Yes |
MED28 | 80306 | 6 | -2.404 | 2.445 | 86 | Yes | - |
TIA1 | 7072 | 4 | -1.234 | 2.263 | 53 | - | - |
CBLL1 | 79872 | 6 | -1.897 | 2.445 | 38 | - | - |
MED13L | 23389 | 8 | -2.550 | 2.307 | 50 | Yes | - |
VARS | 7407 | 8 | -2.366 | 2.689 | 204 | Yes | - |
POU5F1 | 5460 | 12 | -5.148 | 3.538 | 179 | Yes | Yes |
FBXO22 | 26263 | 8 | -1.739 | 2.459 | 208 | - | - |
DENR | 8562 | 4 | -1.023 | 2.263 | 42 | - | - |
PSMD2 | 5708 | 6 | -4.172 | 3.157 | 389 | Yes | Yes |
FOXJ3 | 22887 | 4 | -2.407 | 2.369 | 87 | Yes | Yes |
EIF2S2 | 8894 | 9 | -2.999 | 2.459 | 103 | Yes | Yes |
SUV39H2 | 79723 | 7 | -2.307 | 2.410 | 21 | Yes | Yes |
CASP2 | 835 | 4 | -2.007 | 2.445 | 47 | Yes | - |
MED12 | 9968 | 2 | -2.465 | 3.206 | 65 | Yes | - |
ETF1 | 2107 | 7 | -2.829 | 2.503 | 77 | Yes | Yes |
GTF3C3 | 9330 | 4 | -1.450 | 2.428 | 62 | - | - |
NAP1L4 | 4676 | 2 | -1.947 | 3.119 | 187 | - | - |
CCT7 | 10574 | 10 | -2.335 | 2.459 | 173 | Yes | - |
CPSF3 | 51692 | 7 | -2.686 | 2.503 | 31 | Yes | Yes |
HNRNPU | 3192 | 12 | -2.869 | 2.644 | 172 | Yes | - |
CLASP1 | 23332 | 4 | -2.365 | 2.459 | 39 | Yes | - |
NDUFA4L2 | 56901 | 10 | -2.477 | 2.459 | 21 | Yes | - |
HCFC1 | 3054 | 2 | -2.925 | 3.449 | 71 | Yes | Yes |
MED19 | 219541 | 4 | -2.657 | 3.449 | 115 | Yes | - |
AGPS | 8540 | 6 | -2.424 | 2.410 | 27 | Yes | Yes |
SLC7A5P1 | 81893 | 4 | -3.217 | 2.445 | 4 | Yes | - |
YAP1 | 10413 | 12 | -4.256 | 3.538 | 53 | Yes | - |
NCBP1 | 4686 | 8 | -2.510 | 2.459 | 84 | Yes | Yes |
SYNCRIP | 10492 | 8 | -2.401 | 2.503 | 247 | Yes | Yes |
LUC7L3 | 51747 | 4 | -3.523 | 3.449 | 18 | Yes | - |
ZDHHC20 | 253832 | 4 | -2.673 | 2.326 | 25 | Yes | - |
TADA2B | 93624 | 4 | -3.061 | 3.082 | 19 | Yes | - |
FTSJ1 | 24140 | 5 | -2.463 | 2.689 | 130 | Yes | Yes |
EIF2B2 | 8892 | 4 | -2.462 | 2.968 | 95 | Yes | Yes |
GSPT1 | 2935 | 7 | -2.313 | 2.503 | 47 | Yes | Yes |
SRSF3 | 6428 | 5 | -2.992 | 3.538 | 54 | Yes | - |
NOLC1 | 9221 | 5 | -1.985 | 2.503 | 136 | - | - |
POLH | 5429 | 8 | -2.586 | 2.459 | 24 | Yes | Yes |
BTRC | 8945 | 4 | -1.144 | 2.263 | 64 | - | - |
DDIT3 | 1649 | 11 | -2.825 | 3.504 | 343 | Yes | Yes |
FUBP1 | 8880 | 6 | -2.414 | 2.389 | 41 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
DENR | 8562 | CBLL1 | 79872 | pd | < | reg.ITFP.txt: no annot |
BTRC | 8945 | FOXJ3 | 22887 | pd | <> | reg.ITFP.txt: no annot |
ETF1 | 2107 | SYNCRIP | 10492 | pd | < | reg.ITFP.txt: no annot |
NCBP1 | 4686 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
PHB | 5245 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
TIA1 | 7072 | CLASP1 | 23332 | pd | <> | reg.ITFP.txt: no annot |
EIF2B2 | 8892 | TADA2B | 93624 | pp | -- | int.I2D: BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly, MINT_Fly |
ETF1 | 2107 | GSPT1 | 2935 | pp | -- | int.I2D: MINT, BCI, BioGrid, HPRD; int.Mint: MI:0915(physical association); int.HPRD: in vivo, yeast 2-hybrid |
CCNC | 892 | NAP1L4 | 4676 | pp | -- | int.I2D: BioGrid_Yeast |
HNRNPU | 3192 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
HCFC1 | 3054 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
DDIT3 | 1649 | NAP1L4 | 4676 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
PSMD2 | 5708 | CNOT1 | 23019 | pp | -- | int.I2D: YeastLow |
DENR | 8562 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
CNOT1 | 23019 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
POLH | 5429 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
NOLC1 | 9221 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
GSPT1 | 2935 | SYNCRIP | 10492 | pd | < | reg.ITFP.txt: no annot |
DENR | 8562 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
NCBP1 | 4686 | CBLL1 | 79872 | pd | < | reg.ITFP.txt: no annot |
CCT7 | 10574 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
DENR | 8562 | SYNCRIP | 10492 | pd | < | reg.ITFP.txt: no annot |
DENR | 8562 | GTF3C3 | 9330 | pd | < | reg.ITFP.txt: no annot |
CBLL1 | 79872 | MED28 | 80306 | pd | > | reg.ITFP.txt: no annot |
MED12 | 9968 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
VARS | 7407 | FTSJ1 | 24140 | pd | > | reg.ITFP.txt: no annot |
CCNC | 892 | MED12 | 9968 | pp | -- | int.I2D: BioGrid |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
MED12 | 9968 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
LUC7L3 | 51747 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
HCFC1 | 3054 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
CCNC | 892 | MED13L | 23389 | pp | -- | int.I2D: IntAct_Fly, MINT_Fly |
HNRNPU | 3192 | BTRC | 8945 | pp | -- | int.I2D: BCI, BioGrid, INNATEDB, HPRD; int.HPRD: in vivo |
PSMD2 | 5708 | VARS | 7407 | pp | -- | int.I2D: BioGrid_Yeast |
BTRC | 8945 | ZDHHC20 | 253832 | pd | > | reg.ITFP.txt: no annot |
POU5F1 | 5460 | SRSF3 | 6428 | pp | -- | int.I2D: BioGrid |
NAP1L4 | 4676 | FOXJ3 | 22887 | pd | < | reg.ITFP.txt: no annot |
DDIT3 | 1649 | VARS | 7407 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
MED28 | 80306 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
AGPS | 8540 | SYNCRIP | 10492 | pd | < | reg.ITFP.txt: no annot |
MED13L | 23389 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
CASP2 | 835 | DENR | 8562 | pd | > | reg.ITFP.txt: no annot |
ETF1 | 2107 | EIF2S2 | 8894 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
YAP1 | 10413 | MED28 | 80306 | pp | -- | int.I2D: MINT; int.Mint: MI:0915(physical association) |
BTRC | 8945 | CNOT1 | 23019 | pd | > | reg.ITFP.txt: no annot |
PSMD2 | 5708 | CCT7 | 10574 | pp | -- | int.I2D: BioGrid_Yeast |
CCNC | 892 | EIF2B2 | 8892 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
DENR | 8562 | NOLC1 | 9221 | pd | < | reg.ITFP.txt: no annot |
EIF2B2 | 8892 | EIF2S2 | 8894 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh |
SYNCRIP | 10492 | CPSF3 | 51692 | pd | > | reg.ITFP.txt: no annot |
SRSF3 | 6428 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
EIF2S2 | 8894 | GTF3C3 | 9330 | pd | < | reg.ITFP.txt: no annot |
SYNCRIP | 10492 | SUV39H2 | 79723 | pd | > | reg.ITFP.txt: no annot |
MED13L | 23389 | ANAPC5 | 51433 | pd | < | reg.ITFP.txt: no annot |
CCNC | 892 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
PSMD2 | 5708 | EIF2B2 | 8892 | pp | -- | int.I2D: IntAct_Yeast |
TIA1 | 7072 | DENR | 8562 | pd | > | reg.ITFP.txt: no annot |
CCNC | 892 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
CASP2 | 835 | SLC7A5P1 | 81893 | pd | > | reg.ITFP.txt: no annot |
MED13L | 23389 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
CASP2 | 835 | CBLL1 | 79872 | pd | <> | reg.ITFP.txt: no annot |
NOLC1 | 9221 | FTSJ1 | 24140 | pd | > | reg.ITFP.txt: no annot |
GSPT1 | 2935 | NOLC1 | 9221 | pd | < | reg.ITFP.txt: no annot |
VARS | 7407 | FBXO22 | 26263 | pd | <> | reg.ITFP.txt: no annot |
CCNC | 892 | CNOT1 | 23019 | pp | -- | int.I2D: BioGrid_Yeast |
PHB | 5245 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
HNRNPU | 3192 | SYNCRIP | 10492 | pp | -- | int.Mint: MI:0915(physical association) |
FBXO22 | 26263 | NDUFA4L2 | 56901 | pd | > | reg.ITFP.txt: no annot |
FUBP1 | 8880 | ANAPC5 | 51433 | pd | <> | reg.ITFP.txt: no annot |
ANAPC5 | 51433 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
EIF2S2 | 8894 | FBXO22 | 26263 | pd | < | reg.ITFP.txt: no annot |
DENR | 8562 | BTRC | 8945 | pd | < | reg.ITFP.txt: no annot |
BTRC | 8945 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid, MINT; int.Mint: MI:0915(physical association) |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0010467 | gene expression | 1.70e-09 | 2.77e-05 | 2.924 | 14 | 27 | 669 |
GO:0005654 | nucleoplasm | 1.53e-08 | 2.50e-04 | 2.406 | 16 | 31 | 1095 |
GO:0016592 | mediator complex | 3.87e-08 | 6.31e-04 | 5.695 | 5 | 5 | 35 |
GO:0044822 | poly(A) RNA binding | 6.66e-07 | 1.09e-02 | 2.236 | 14 | 27 | 1078 |
GO:0005515 | protein binding | 1.12e-06 | 1.83e-02 | 0.966 | 33 | 77 | 6127 |
GO:0006366 | transcription from RNA polymerase II promoter | 1.83e-05 | 2.99e-01 | 2.771 | 8 | 14 | 425 |
GO:0008380 | RNA splicing | 3.96e-05 | 6.47e-01 | 3.230 | 6 | 14 | 232 |
GO:0003747 | translation release factor activity | 4.44e-05 | 7.25e-01 | 7.503 | 2 | 2 | 4 |
GO:0003723 | RNA binding | 4.84e-05 | 7.89e-01 | 2.838 | 7 | 15 | 355 |
GO:0070461 | SAGA-type complex | 7.39e-05 | 1.00e+00 | 7.181 | 2 | 2 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 7.39e-05 | 1.00e+00 | 7.181 | 2 | 2 | 5 |
GO:0000398 | mRNA splicing, via spliceosome | 8.76e-05 | 1.00e+00 | 3.458 | 5 | 9 | 165 |
GO:0001104 | RNA polymerase II transcription cofactor activity | 1.01e-04 | 1.00e+00 | 5.043 | 3 | 3 | 33 |
GO:0070937 | CRD-mediated mRNA stability complex | 1.11e-04 | 1.00e+00 | 6.918 | 2 | 2 | 6 |
GO:0031124 | mRNA 3'-end processing | 2.09e-04 | 1.00e+00 | 4.695 | 3 | 4 | 42 |
GO:0006369 | termination of RNA polymerase II transcription | 2.56e-04 | 1.00e+00 | 4.596 | 3 | 4 | 45 |
GO:0030529 | ribonucleoprotein complex | 2.70e-04 | 1.00e+00 | 3.670 | 4 | 6 | 114 |
GO:0006379 | mRNA cleavage | 3.30e-04 | 1.00e+00 | 6.181 | 2 | 2 | 10 |
GO:0003743 | translation initiation factor activity | 3.30e-04 | 1.00e+00 | 4.473 | 3 | 5 | 49 |
GO:0008143 | poly(A) binding | 4.82e-04 | 1.00e+00 | 5.918 | 2 | 2 | 12 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 5.69e-04 | 1.00e+00 | 5.802 | 2 | 2 | 13 |
GO:0006406 | mRNA export from nucleus | 6.61e-04 | 1.00e+00 | 4.133 | 3 | 5 | 62 |
GO:0006479 | protein methylation | 7.63e-04 | 1.00e+00 | 5.596 | 2 | 2 | 15 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 9.42e-04 | 1.00e+00 | 3.958 | 3 | 4 | 70 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.11e-03 | 1.00e+00 | 3.878 | 3 | 4 | 74 |
GO:0044212 | transcription regulatory region DNA binding | 1.24e-03 | 1.00e+00 | 3.085 | 4 | 5 | 171 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.34e-03 | 1.00e+00 | 3.784 | 3 | 4 | 79 |
GO:0014003 | oligodendrocyte development | 1.37e-03 | 1.00e+00 | 5.181 | 2 | 3 | 20 |
GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 1.66e-03 | 1.00e+00 | 5.043 | 2 | 2 | 22 |
GO:0016020 | membrane | 2.15e-03 | 1.00e+00 | 1.318 | 12 | 27 | 1746 |
GO:0001649 | osteoblast differentiation | 2.27e-03 | 1.00e+00 | 3.518 | 3 | 3 | 95 |
GO:0031047 | gene silencing by RNA | 2.32e-03 | 1.00e+00 | 4.802 | 2 | 2 | 26 |
GO:0005829 | cytosol | 2.64e-03 | 1.00e+00 | 1.086 | 15 | 38 | 2562 |
GO:0002128 | tRNA nucleoside ribose methylation | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0008609 | alkylglycerone-phosphate synthase activity | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0031592 | centrosomal corona | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0097165 | nuclear stress granule | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0008079 | translation termination factor activity | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
GO:0016071 | mRNA metabolic process | 3.26e-03 | 1.00e+00 | 2.702 | 4 | 8 | 223 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 3.80e-03 | 1.00e+00 | 3.255 | 3 | 3 | 114 |
GO:0000209 | protein polyubiquitination | 3.99e-03 | 1.00e+00 | 3.230 | 3 | 5 | 116 |
GO:0006446 | regulation of translational initiation | 4.41e-03 | 1.00e+00 | 4.333 | 2 | 2 | 36 |
GO:0016070 | RNA metabolic process | 4.69e-03 | 1.00e+00 | 2.554 | 4 | 8 | 247 |
GO:0004832 | valine-tRNA ligase activity | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0008175 | tRNA methyltransferase activity | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0019046 | release from viral latency | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0005846 | nuclear cap binding complex | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0002176 | male germ cell proliferation | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0045309 | protein phosphorylated amino acid binding | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0001554 | luteolysis | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0060965 | negative regulation of gene silencing by miRNA | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0031111 | negative regulation of microtubule polymerization or depolymerization | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0030981 | cortical microtubule cytoskeleton | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0051294 | establishment of spindle orientation | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
GO:0017148 | negative regulation of translation | 5.69e-03 | 1.00e+00 | 4.145 | 2 | 3 | 41 |
GO:0043525 | positive regulation of neuron apoptotic process | 7.12e-03 | 1.00e+00 | 3.979 | 2 | 2 | 46 |
GO:0048511 | rhythmic process | 7.43e-03 | 1.00e+00 | 3.948 | 2 | 2 | 47 |
GO:0019827 | stem cell maintenance | 7.74e-03 | 1.00e+00 | 3.918 | 2 | 2 | 48 |
GO:0036123 | histone H3-K9 dimethylation | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
GO:0090245 | axis elongation involved in somitogenesis | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 2 | 3 |
GO:0016149 | translation release factor activity, codon specific | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
GO:0005778 | peroxisomal membrane | 8.37e-03 | 1.00e+00 | 3.859 | 2 | 2 | 50 |
GO:0006355 | regulation of transcription, DNA-templated | 9.80e-03 | 1.00e+00 | 1.394 | 8 | 13 | 1104 |
GO:0014044 | Schwann cell development | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0051716 | cellular response to stimulus | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 2 | 4 |
GO:0042036 | negative regulation of cytokine biosynthetic process | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0097452 | GAIT complex | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 2 | 4 |
GO:0060913 | cardiac cell fate determination | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0007000 | nucleolus organization | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0008611 | ether lipid biosynthetic process | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0051151 | negative regulation of smooth muscle cell differentiation | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0046523 | S-methyl-5-thioribose-1-phosphate isomerase activity | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0006290 | pyrimidine dimer repair | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0043515 | kinetochore binding | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0002192 | IRES-dependent translational initiation | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
GO:0044267 | cellular protein metabolic process | 1.13e-02 | 1.00e+00 | 1.873 | 5 | 7 | 495 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 1.15e-02 | 1.00e+00 | 3.620 | 2 | 2 | 59 |
GO:0006396 | RNA processing | 1.19e-02 | 1.00e+00 | 3.596 | 2 | 4 | 60 |
GO:0008013 | beta-catenin binding | 1.19e-02 | 1.00e+00 | 3.596 | 2 | 4 | 60 |
GO:0003682 | chromatin binding | 1.33e-02 | 1.00e+00 | 2.119 | 4 | 7 | 334 |
GO:0001714 | endodermal cell fate specification | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0003407 | neural retina development | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0005828 | kinetochore microtubule | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0031023 | microtubule organizing center organization | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0048742 | regulation of skeletal muscle fiber development | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0006398 | histone mRNA 3'-end processing | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0045292 | mRNA cis splicing, via spliceosome | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0031442 | positive regulation of mRNA 3'-end processing | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0006449 | regulation of translational termination | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0036124 | histone H3-K9 trimethylation | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.38e-02 | 1.00e+00 | 3.480 | 2 | 3 | 65 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.38e-02 | 1.00e+00 | 3.480 | 2 | 3 | 65 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.41e-02 | 1.00e+00 | 2.564 | 3 | 5 | 184 |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:0042797 | tRNA transcription from RNA polymerase III promoter | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 2 | 6 |
GO:0050847 | progesterone receptor signaling pathway | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:0002181 | cytoplasmic translation | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:0046974 | histone methyltransferase activity (H3-K9 specific) | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:0048024 | regulation of mRNA splicing, via spliceosome | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:0005851 | eukaryotic translation initiation factor 2B complex | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 3 | 6 |
GO:0000127 | transcription factor TFIIIC complex | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 2 | 6 |
GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 2 | 6 |
GO:0006333 | chromatin assembly or disassembly | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:0071204 | histone pre-mRNA 3'end processing complex | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 1.86e-02 | 1.00e+00 | 3.255 | 2 | 2 | 76 |
GO:0032790 | ribosome disassembly | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0042753 | positive regulation of circadian rhythm | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0004521 | endoribonuclease activity | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0010458 | exit from mitosis | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0006301 | postreplication repair | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0006282 | regulation of DNA repair | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0035234 | ectopic germ cell programmed cell death | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
GO:0071013 | catalytic step 2 spliceosome | 2.00e-02 | 1.00e+00 | 3.199 | 2 | 3 | 79 |
GO:0042754 | negative regulation of circadian rhythm | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 1 | 8 |
GO:0001955 | blood vessel maturation | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 1 | 8 |
GO:0000339 | RNA cap binding | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 1 | 8 |
GO:0043254 | regulation of protein complex assembly | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 1 | 8 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 2.31e-02 | 1.00e+00 | 1.424 | 6 | 13 | 811 |
GO:0005739 | mitochondrion | 2.33e-02 | 1.00e+00 | 1.279 | 7 | 16 | 1046 |
GO:0000278 | mitotic cell cycle | 2.36e-02 | 1.00e+00 | 1.866 | 4 | 12 | 398 |
GO:0006415 | translational termination | 2.40e-02 | 1.00e+00 | 3.060 | 2 | 2 | 87 |
GO:0071354 | cellular response to interleukin-6 | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0008409 | 5'-3' exonuclease activity | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0016591 | DNA-directed RNA polymerase II, holoenzyme | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0043996 | histone acetyltransferase activity (H4-K8 specific) | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0043995 | histone acetyltransferase activity (H4-K5 specific) | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0033598 | mammary gland epithelial cell proliferation | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0046972 | histone acetyltransferase activity (H4-K16 specific) | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0019509 | L-methionine biosynthetic process from methylthioadenosine | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0048188 | Set1C/COMPASS complex | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0005832 | chaperonin-containing T-complex | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
GO:0006412 | translation | 2.68e-02 | 1.00e+00 | 2.211 | 3 | 5 | 235 |
GO:0008610 | lipid biosynthetic process | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
GO:0002199 | zona pellucida receptor complex | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
GO:0006450 | regulation of translational fidelity | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
GO:0071949 | FAD binding | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
GO:0010225 | response to UV-C | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 2 | 10 |
GO:0000731 | DNA synthesis involved in DNA repair | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 2 | 10 |
GO:0010944 | negative regulation of transcription by competitive promoter binding | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
GO:0003713 | transcription coactivator activity | 2.80e-02 | 1.00e+00 | 2.187 | 3 | 7 | 239 |
GO:0051082 | unfolded protein binding | 2.82e-02 | 1.00e+00 | 2.933 | 2 | 3 | 95 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.90e-02 | 1.00e+00 | 1.775 | 4 | 7 | 424 |
GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0005845 | mRNA cap binding complex | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0051010 | microtubule plus-end binding | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 2 | 11 |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0048387 | negative regulation of retinoic acid receptor signaling pathway | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0045662 | negative regulation of myoblast differentiation | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0035413 | positive regulation of catenin import into nucleus | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0004535 | poly(A)-specific ribonuclease activity | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:2000036 | regulation of stem cell maintenance | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
GO:0034453 | microtubule anchoring | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
GO:0061136 | regulation of proteasomal protein catabolic process | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
GO:0008334 | histone mRNA metabolic process | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
GO:0005838 | proteasome regulatory particle | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
GO:0004842 | ubiquitin-protein transferase activity | 3.34e-02 | 1.00e+00 | 2.088 | 3 | 5 | 256 |
GO:0007140 | male meiosis | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
GO:0042974 | retinoic acid receptor binding | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
GO:0060766 | negative regulation of androgen receptor signaling pathway | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
GO:0030914 | STAGA complex | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
GO:0060444 | branching involved in mammary gland duct morphogenesis | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
GO:0035198 | miRNA binding | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
GO:0030518 | intracellular steroid hormone receptor signaling pathway | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
GO:0071480 | cellular response to gamma radiation | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
GO:0005685 | U1 snRNP | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
GO:0007020 | microtubule nucleation | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
GO:0045807 | positive regulation of endocytosis | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
GO:0000166 | nucleotide binding | 3.89e-02 | 1.00e+00 | 2.000 | 3 | 6 | 272 |
GO:0042809 | vitamin D receptor binding | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
GO:0043981 | histone H4-K5 acetylation | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
GO:0017091 | AU-rich element binding | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 2 | 15 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
GO:0001824 | blastocyst development | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
GO:0043982 | histone H4-K8 acetylation | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
GO:0030014 | CCR4-NOT complex | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
GO:0006376 | mRNA splice site selection | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
GO:0007026 | negative regulation of microtubule depolymerization | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 2 | 16 |
GO:0042176 | regulation of protein catabolic process | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 1 | 16 |
GO:0001190 | RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 1 | 16 |
GO:0045893 | positive regulation of transcription, DNA-templated | 4.46e-02 | 1.00e+00 | 1.575 | 4 | 6 | 487 |
GO:0006325 | chromatin organization | 4.52e-02 | 1.00e+00 | 2.560 | 2 | 3 | 123 |
GO:0001829 | trophectodermal cell differentiation | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 2 | 17 |
GO:0043274 | phospholipase binding | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
GO:0001731 | formation of translation preinitiation complex | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
GO:0016409 | palmitoyltransferase activity | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
GO:0022624 | proteasome accessory complex | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 4.79e-02 | 1.00e+00 | 2.514 | 2 | 3 | 127 |
GO:0005634 | nucleus | 4.80e-02 | 1.00e+00 | 0.513 | 19 | 55 | 4828 |
GO:0006413 | translational initiation | 5.06e-02 | 1.00e+00 | 2.469 | 2 | 4 | 131 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 1 | 19 |
GO:0043984 | histone H4-K16 acetylation | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 1 | 19 |
GO:0001578 | microtubule bundle formation | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 20 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 5.38e-02 | 1.00e+00 | 1.278 | 5 | 10 | 748 |
GO:0097194 | execution phase of apoptosis | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 20 |
GO:0005680 | anaphase-promoting complex | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 20 |
GO:0018345 | protein palmitoylation | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 20 |
GO:0000086 | G2/M transition of mitotic cell cycle | 5.48e-02 | 1.00e+00 | 2.405 | 2 | 3 | 137 |
GO:0045862 | positive regulation of proteolysis | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 2 | 21 |
GO:0032757 | positive regulation of interleukin-8 production | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 1 | 21 |
GO:0031648 | protein destabilization | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 2 | 21 |
GO:0000123 | histone acetyltransferase complex | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 2 | 21 |
GO:0016575 | histone deacetylation | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 1 | 21 |
GO:0016055 | Wnt signaling pathway | 5.76e-02 | 1.00e+00 | 2.363 | 2 | 3 | 141 |
GO:0005720 | nuclear heterochromatin | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 1 | 22 |
GO:0006378 | mRNA polyadenylation | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 1 | 22 |
GO:0016032 | viral process | 6.08e-02 | 1.00e+00 | 1.426 | 4 | 16 | 540 |
GO:0005525 | GTP binding | 6.15e-02 | 1.00e+00 | 1.730 | 3 | 5 | 328 |
GO:0071346 | cellular response to interferon-gamma | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 2 | 23 |
GO:0034660 | ncRNA metabolic process | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 1 | 23 |
GO:0019706 | protein-cysteine S-palmitoyltransferase activity | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 1 | 23 |
GO:0045787 | positive regulation of cell cycle | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 1 | 23 |
GO:0045879 | negative regulation of smoothened signaling pathway | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 1 | 23 |
GO:0010628 | positive regulation of gene expression | 6.35e-02 | 1.00e+00 | 2.283 | 2 | 2 | 149 |
GO:0008135 | translation factor activity, nucleic acid binding | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 2 | 24 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 1 | 24 |
GO:0007163 | establishment or maintenance of cell polarity | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 1 | 24 |
GO:0000082 | G1/S transition of mitotic cell cycle | 6.43e-02 | 1.00e+00 | 2.274 | 2 | 4 | 150 |
GO:0042981 | regulation of apoptotic process | 6.50e-02 | 1.00e+00 | 2.264 | 2 | 3 | 151 |
GO:0030864 | cortical actin cytoskeleton | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 1 | 25 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 1 | 25 |
GO:0035329 | hippo signaling | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 1 | 26 |
GO:0070979 | protein K11-linked ubiquitination | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 1 | 26 |
GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 1 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 2 | 26 |
GO:0046966 | thyroid hormone receptor binding | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 1 | 26 |
GO:0006974 | cellular response to DNA damage stimulus | 7.04e-02 | 1.00e+00 | 2.199 | 2 | 4 | 158 |
GO:0006913 | nucleocytoplasmic transport | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 1 | 27 |
GO:0030331 | estrogen receptor binding | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 2 | 27 |
GO:0000387 | spliceosomal snRNP assembly | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 1 | 27 |
GO:0071339 | MLL1 complex | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 1 | 27 |
GO:0007339 | binding of sperm to zona pellucida | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 1 | 27 |
GO:2001235 | positive regulation of apoptotic signaling pathway | 7.45e-02 | 1.00e+00 | 3.695 | 1 | 1 | 28 |
GO:0000976 | transcription regulatory region sequence-specific DNA binding | 7.45e-02 | 1.00e+00 | 3.695 | 1 | 1 | 28 |
GO:0043022 | ribosome binding | 7.45e-02 | 1.00e+00 | 3.695 | 1 | 2 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 1 | 29 |
GO:0016485 | protein processing | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 1 | 29 |
GO:0003887 | DNA-directed DNA polymerase activity | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 1 | 29 |
GO:0071897 | DNA biosynthetic process | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 1 | 29 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 7.83e-02 | 1.00e+00 | 1.300 | 4 | 10 | 589 |
GO:0043565 | sequence-specific DNA binding | 7.91e-02 | 1.00e+00 | 1.576 | 3 | 3 | 365 |
GO:0006370 | 7-methylguanosine mRNA capping | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 2 | 30 |
GO:0010494 | cytoplasmic stress granule | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 2 | 30 |
GO:0007094 | mitotic spindle assembly checkpoint | 8.21e-02 | 1.00e+00 | 3.548 | 1 | 3 | 31 |
GO:0005782 | peroxisomal matrix | 8.21e-02 | 1.00e+00 | 3.548 | 1 | 1 | 31 |
GO:0016607 | nuclear speck | 8.39e-02 | 1.00e+00 | 2.051 | 2 | 6 | 175 |
GO:0042594 | response to starvation | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 3 | 32 |
GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 1 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 1 | 32 |
GO:0007049 | cell cycle | 8.55e-02 | 1.00e+00 | 2.035 | 2 | 4 | 177 |
GO:0007162 | negative regulation of cell adhesion | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 1 | 33 |
GO:0003714 | transcription corepressor activity | 8.72e-02 | 1.00e+00 | 2.019 | 2 | 5 | 179 |
GO:0019904 | protein domain specific binding | 8.88e-02 | 1.00e+00 | 2.003 | 2 | 2 | 181 |
GO:0005876 | spindle microtubule | 8.97e-02 | 1.00e+00 | 3.415 | 1 | 1 | 34 |
GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 9.22e-02 | 1.00e+00 | 3.373 | 1 | 1 | 35 |
GO:0009267 | cellular response to starvation | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 1 | 36 |
GO:0042552 | myelination | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 2 | 36 |
GO:0030178 | negative regulation of Wnt signaling pathway | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 9.72e-02 | 1.00e+00 | 3.293 | 1 | 1 | 37 |
GO:0001541 | ovarian follicle development | 9.72e-02 | 1.00e+00 | 3.293 | 1 | 1 | 37 |
GO:0042752 | regulation of circadian rhythm | 9.72e-02 | 1.00e+00 | 3.293 | 1 | 3 | 37 |
GO:0006383 | transcription from RNA polymerase III promoter | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 3 | 39 |
GO:0071407 | cellular response to organic cyclic compound | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 3 | 39 |
GO:0009408 | response to heat | 1.05e-01 | 1.00e+00 | 3.181 | 1 | 2 | 40 |
GO:0035019 | somatic stem cell maintenance | 1.05e-01 | 1.00e+00 | 3.181 | 1 | 2 | 40 |
GO:0005881 | cytoplasmic microtubule | 1.07e-01 | 1.00e+00 | 3.145 | 1 | 2 | 41 |
GO:0030521 | androgen receptor signaling pathway | 1.07e-01 | 1.00e+00 | 3.145 | 1 | 1 | 41 |
GO:0006418 | tRNA aminoacylation for protein translation | 1.10e-01 | 1.00e+00 | 3.110 | 1 | 3 | 42 |
GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity | 1.12e-01 | 1.00e+00 | 3.076 | 1 | 1 | 43 |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 1.15e-01 | 1.00e+00 | 3.043 | 1 | 1 | 44 |
GO:0003712 | transcription cofactor activity | 1.15e-01 | 1.00e+00 | 3.043 | 1 | 1 | 44 |
GO:0050434 | positive regulation of viral transcription | 1.15e-01 | 1.00e+00 | 3.043 | 1 | 2 | 44 |
GO:0015030 | Cajal body | 1.17e-01 | 1.00e+00 | 3.011 | 1 | 1 | 45 |
GO:0044297 | cell body | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 1 | 46 |
GO:0043434 | response to peptide hormone | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 2 | 46 |
GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 1.22e-01 | 1.00e+00 | 2.948 | 1 | 1 | 47 |
GO:0008630 | intrinsic apoptotic signaling pathway in response to DNA damage | 1.27e-01 | 1.00e+00 | 2.888 | 1 | 1 | 49 |
GO:0016874 | ligase activity | 1.27e-01 | 1.00e+00 | 1.695 | 2 | 4 | 224 |
GO:0006521 | regulation of cellular amino acid metabolic process | 1.29e-01 | 1.00e+00 | 2.859 | 1 | 2 | 50 |
GO:0006986 | response to unfolded protein | 1.32e-01 | 1.00e+00 | 2.830 | 1 | 2 | 51 |
GO:0003684 | damaged DNA binding | 1.32e-01 | 1.00e+00 | 2.830 | 1 | 1 | 51 |
GO:0007067 | mitotic nuclear division | 1.33e-01 | 1.00e+00 | 1.651 | 2 | 4 | 231 |
GO:0000775 | chromosome, centromeric region | 1.34e-01 | 1.00e+00 | 2.802 | 1 | 3 | 52 |
GO:0004197 | cysteine-type endopeptidase activity | 1.34e-01 | 1.00e+00 | 2.802 | 1 | 1 | 52 |
GO:0034976 | response to endoplasmic reticulum stress | 1.34e-01 | 1.00e+00 | 2.802 | 1 | 1 | 52 |
GO:0045454 | cell redox homeostasis | 1.34e-01 | 1.00e+00 | 2.802 | 1 | 1 | 52 |
GO:0009611 | response to wounding | 1.36e-01 | 1.00e+00 | 2.775 | 1 | 1 | 53 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 1.36e-01 | 1.00e+00 | 2.775 | 1 | 2 | 53 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1.39e-01 | 1.00e+00 | 2.748 | 1 | 1 | 54 |
GO:0000226 | microtubule cytoskeleton organization | 1.41e-01 | 1.00e+00 | 2.721 | 1 | 2 | 55 |
GO:0006351 | transcription, DNA-templated | 1.42e-01 | 1.00e+00 | 0.680 | 7 | 17 | 1585 |
GO:0000932 | cytoplasmic mRNA processing body | 1.43e-01 | 1.00e+00 | 2.695 | 1 | 2 | 56 |
GO:0008134 | transcription factor binding | 1.47e-01 | 1.00e+00 | 1.560 | 2 | 6 | 246 |
GO:0000502 | proteasome complex | 1.48e-01 | 1.00e+00 | 2.645 | 1 | 2 | 58 |
GO:0042802 | identical protein binding | 1.53e-01 | 1.00e+00 | 1.148 | 3 | 6 | 491 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 1.58e-01 | 1.00e+00 | 2.548 | 1 | 2 | 62 |
GO:0000151 | ubiquitin ligase complex | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 2 | 63 |
GO:0019903 | protein phosphatase binding | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 1 | 63 |
GO:0000776 | kinetochore | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 4 | 63 |
GO:0006417 | regulation of translation | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 1 | 63 |
GO:0009749 | response to glucose | 1.62e-01 | 1.00e+00 | 2.503 | 1 | 2 | 64 |
GO:0003677 | DNA binding | 1.65e-01 | 1.00e+00 | 0.688 | 6 | 16 | 1351 |
GO:0071260 | cellular response to mechanical stimulus | 1.67e-01 | 1.00e+00 | 2.458 | 1 | 1 | 66 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 1.69e-01 | 1.00e+00 | 2.436 | 1 | 3 | 67 |
GO:0006338 | chromatin remodeling | 1.71e-01 | 1.00e+00 | 2.415 | 1 | 1 | 68 |
GO:0000777 | condensed chromosome kinetochore | 1.71e-01 | 1.00e+00 | 2.415 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 1.74e-01 | 1.00e+00 | 2.394 | 1 | 2 | 69 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 1.75e-01 | 1.00e+00 | 1.399 | 2 | 4 | 275 |
GO:0005730 | nucleolus | 1.77e-01 | 1.00e+00 | 0.592 | 7 | 28 | 1684 |
GO:0010468 | regulation of gene expression | 1.81e-01 | 1.00e+00 | 2.333 | 1 | 1 | 72 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.83e-01 | 1.00e+00 | 2.313 | 1 | 2 | 73 |
GO:0003729 | mRNA binding | 1.83e-01 | 1.00e+00 | 2.313 | 1 | 3 | 73 |
GO:0000785 | chromatin | 1.83e-01 | 1.00e+00 | 2.313 | 1 | 2 | 73 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 1.85e-01 | 1.00e+00 | 2.293 | 1 | 2 | 74 |
GO:0042826 | histone deacetylase binding | 1.85e-01 | 1.00e+00 | 2.293 | 1 | 2 | 74 |
GO:0060070 | canonical Wnt signaling pathway | 1.87e-01 | 1.00e+00 | 2.274 | 1 | 2 | 75 |
GO:0001843 | neural tube closure | 1.87e-01 | 1.00e+00 | 2.274 | 1 | 1 | 75 |
GO:0019899 | enzyme binding | 1.88e-01 | 1.00e+00 | 1.333 | 2 | 3 | 288 |
GO:0008584 | male gonad development | 1.92e-01 | 1.00e+00 | 2.236 | 1 | 1 | 77 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.92e-01 | 1.00e+00 | 2.236 | 1 | 2 | 77 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 1.92e-01 | 1.00e+00 | 2.236 | 1 | 2 | 77 |
GO:0006334 | nucleosome assembly | 1.96e-01 | 1.00e+00 | 2.199 | 1 | 3 | 79 |
GO:0016567 | protein ubiquitination | 1.99e-01 | 1.00e+00 | 1.279 | 2 | 5 | 299 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 2.01e-01 | 1.00e+00 | 2.163 | 1 | 2 | 81 |
GO:0051301 | cell division | 2.01e-01 | 1.00e+00 | 2.163 | 1 | 2 | 81 |
GO:0006915 | apoptotic process | 2.08e-01 | 1.00e+00 | 0.930 | 3 | 8 | 571 |
GO:0009653 | anatomical structure morphogenesis | 2.14e-01 | 1.00e+00 | 2.060 | 1 | 1 | 87 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 2.16e-01 | 1.00e+00 | 2.043 | 1 | 4 | 88 |
GO:0006464 | cellular protein modification process | 2.18e-01 | 1.00e+00 | 2.027 | 1 | 1 | 89 |
GO:0005777 | peroxisome | 2.21e-01 | 1.00e+00 | 2.011 | 1 | 1 | 90 |
GO:0050821 | protein stabilization | 2.23e-01 | 1.00e+00 | 1.995 | 1 | 3 | 91 |
GO:0016337 | single organismal cell-cell adhesion | 2.25e-01 | 1.00e+00 | 1.979 | 1 | 1 | 92 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 2.29e-01 | 1.00e+00 | 1.948 | 1 | 2 | 94 |
GO:0005770 | late endosome | 2.29e-01 | 1.00e+00 | 1.948 | 1 | 1 | 94 |
GO:0006364 | rRNA processing | 2.33e-01 | 1.00e+00 | 1.918 | 1 | 2 | 96 |
GO:0030018 | Z disc | 2.38e-01 | 1.00e+00 | 1.888 | 1 | 2 | 98 |
GO:0071456 | cellular response to hypoxia | 2.38e-01 | 1.00e+00 | 1.888 | 1 | 2 | 98 |
GO:0006470 | protein dephosphorylation | 2.40e-01 | 1.00e+00 | 1.873 | 1 | 1 | 99 |
GO:0007417 | central nervous system development | 2.44e-01 | 1.00e+00 | 1.844 | 1 | 2 | 101 |
GO:0051726 | regulation of cell cycle | 2.46e-01 | 1.00e+00 | 1.830 | 1 | 4 | 102 |
GO:0005938 | cell cortex | 2.61e-01 | 1.00e+00 | 1.734 | 1 | 1 | 109 |
GO:0030308 | negative regulation of cell growth | 2.69e-01 | 1.00e+00 | 1.682 | 1 | 2 | 113 |
GO:0097190 | apoptotic signaling pathway | 2.75e-01 | 1.00e+00 | 1.645 | 1 | 1 | 116 |
GO:0005737 | cytoplasm | 2.89e-01 | 1.00e+00 | 0.246 | 13 | 43 | 3976 |
GO:0007568 | aging | 2.89e-01 | 1.00e+00 | 1.560 | 1 | 2 | 123 |
GO:0007219 | Notch signaling pathway | 2.93e-01 | 1.00e+00 | 1.537 | 1 | 2 | 125 |
GO:0006260 | DNA replication | 2.93e-01 | 1.00e+00 | 1.537 | 1 | 4 | 125 |
GO:0007050 | cell cycle arrest | 2.95e-01 | 1.00e+00 | 1.525 | 1 | 3 | 126 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 3.03e-01 | 1.00e+00 | 1.480 | 1 | 1 | 130 |
GO:0030335 | positive regulation of cell migration | 3.03e-01 | 1.00e+00 | 1.480 | 1 | 2 | 130 |
GO:0046983 | protein dimerization activity | 3.05e-01 | 1.00e+00 | 1.469 | 1 | 1 | 131 |
GO:0005524 | ATP binding | 3.17e-01 | 1.00e+00 | 0.422 | 5 | 13 | 1354 |
GO:0044255 | cellular lipid metabolic process | 3.22e-01 | 1.00e+00 | 1.373 | 1 | 1 | 140 |
GO:0007507 | heart development | 3.24e-01 | 1.00e+00 | 1.363 | 1 | 2 | 141 |
GO:0008270 | zinc ion binding | 3.39e-01 | 1.00e+00 | 0.443 | 4 | 11 | 1067 |
GO:0006457 | protein folding | 3.39e-01 | 1.00e+00 | 1.283 | 1 | 1 | 149 |
GO:0008017 | microtubule binding | 3.40e-01 | 1.00e+00 | 1.274 | 1 | 4 | 150 |
GO:0008022 | protein C-terminus binding | 3.60e-01 | 1.00e+00 | 1.172 | 1 | 1 | 161 |
GO:0007420 | brain development | 3.80e-01 | 1.00e+00 | 1.076 | 1 | 1 | 172 |
GO:0034641 | cellular nitrogen compound metabolic process | 3.88e-01 | 1.00e+00 | 1.035 | 1 | 3 | 177 |
GO:0005667 | transcription factor complex | 3.90e-01 | 1.00e+00 | 1.027 | 1 | 3 | 178 |
GO:0031625 | ubiquitin protein ligase binding | 3.93e-01 | 1.00e+00 | 1.011 | 1 | 2 | 180 |
GO:0043547 | positive regulation of GTPase activity | 4.10e-01 | 1.00e+00 | 0.933 | 1 | 2 | 190 |
GO:0004872 | receptor activity | 4.25e-01 | 1.00e+00 | 0.866 | 1 | 1 | 199 |
GO:0003924 | GTPase activity | 4.31e-01 | 1.00e+00 | 0.837 | 1 | 2 | 203 |
GO:0001701 | in utero embryonic development | 4.42e-01 | 1.00e+00 | 0.788 | 1 | 2 | 210 |
GO:0006184 | GTP catabolic process | 4.57e-01 | 1.00e+00 | 0.721 | 1 | 2 | 220 |
GO:0005622 | intracellular | 4.67e-01 | 1.00e+00 | 0.682 | 1 | 2 | 226 |
GO:0043025 | neuronal cell body | 5.07e-01 | 1.00e+00 | 0.514 | 1 | 3 | 254 |
GO:0005874 | microtubule | 5.12e-01 | 1.00e+00 | 0.491 | 1 | 3 | 258 |
GO:0006281 | DNA repair | 5.20e-01 | 1.00e+00 | 0.458 | 1 | 4 | 264 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 5.32e-01 | 1.00e+00 | 0.410 | 1 | 2 | 273 |
GO:0043065 | positive regulation of apoptotic process | 5.34e-01 | 1.00e+00 | 0.405 | 1 | 3 | 274 |
GO:0003779 | actin binding | 5.35e-01 | 1.00e+00 | 0.399 | 1 | 1 | 275 |
GO:0005743 | mitochondrial inner membrane | 5.67e-01 | 1.00e+00 | 0.274 | 1 | 3 | 300 |
GO:0019901 | protein kinase binding | 5.90e-01 | 1.00e+00 | 0.181 | 1 | 4 | 320 |
GO:0005575 | cellular_component | 5.93e-01 | 1.00e+00 | 0.172 | 1 | 1 | 322 |
GO:0030154 | cell differentiation | 5.96e-01 | 1.00e+00 | 0.158 | 1 | 2 | 325 |
GO:0007411 | axon guidance | 5.98e-01 | 1.00e+00 | 0.149 | 1 | 2 | 327 |
GO:0008283 | cell proliferation | 6.03e-01 | 1.00e+00 | 0.132 | 1 | 3 | 331 |
GO:0043231 | intracellular membrane-bounded organelle | 6.04e-01 | 1.00e+00 | 0.128 | 1 | 1 | 332 |
GO:0005813 | centrosome | 6.12e-01 | 1.00e+00 | 0.097 | 1 | 4 | 339 |
GO:0008285 | negative regulation of cell proliferation | 6.41e-01 | 1.00e+00 | -0.017 | 1 | 4 | 367 |
GO:0005925 | focal adhesion | 6.44e-01 | 1.00e+00 | -0.029 | 1 | 2 | 370 |
GO:0046982 | protein heterodimerization activity | 6.72e-01 | 1.00e+00 | -0.138 | 1 | 3 | 399 |
GO:0006508 | proteolysis | 6.82e-01 | 1.00e+00 | -0.177 | 1 | 2 | 410 |
GO:0009986 | cell surface | 6.93e-01 | 1.00e+00 | -0.219 | 1 | 4 | 422 |
GO:0043066 | negative regulation of apoptotic process | 7.02e-01 | 1.00e+00 | -0.256 | 1 | 5 | 433 |
GO:0055114 | oxidation-reduction process | 7.40e-01 | 1.00e+00 | -0.407 | 1 | 2 | 481 |
GO:0007165 | signal transduction | 7.46e-01 | 1.00e+00 | -0.389 | 2 | 8 | 950 |
GO:0003674 | molecular_function | 7.70e-01 | 1.00e+00 | -0.531 | 1 | 1 | 524 |
GO:0046872 | metal ion binding | 7.82e-01 | 1.00e+00 | -0.429 | 3 | 6 | 1465 |
GO:0005783 | endoplasmic reticulum | 8.20e-01 | 1.00e+00 | -0.750 | 1 | 2 | 610 |
GO:0005794 | Golgi apparatus | 8.40e-01 | 1.00e+00 | -0.842 | 1 | 1 | 650 |
GO:0044281 | small molecule metabolic process | 8.82e-01 | 1.00e+00 | -0.836 | 2 | 12 | 1295 |
GO:0070062 | extracellular vesicular exosome | 9.32e-01 | 1.00e+00 | -0.794 | 4 | 15 | 2516 |
GO:0005887 | integral component of plasma membrane | 9.35e-01 | 1.00e+00 | -1.406 | 1 | 1 | 961 |
GO:0005615 | extracellular space | 9.44e-01 | 1.00e+00 | -1.478 | 1 | 4 | 1010 |
GO:0005886 | plasma membrane | 9.90e-01 | 1.00e+00 | -1.381 | 3 | 14 | 2834 |
GO:0016021 | integral component of membrane | 9.99e-01 | 1.00e+00 | -2.775 | 1 | 7 | 2483 |