meta-int-snw-892

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-8562 chia-screen-data-Fav 2.263 1.35e-07 3.15e-02 2.44e-02 32 24
int-snw-892 chia-screen-data-Fav 2.968 5.68e-17 8.94e-05 1.03e-03 17 15
chia-screen-data-Fav-meta-int-snw-892 subnetwork

Genes (45)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Chia-Hits Primary Chia-Hits Secondary
CCNC 892 2-1.7262.968101--
ANAPC5 51433 6-1.2642.263239--
CNOT1 23019 7-2.3472.263124Yes-
PHB 5245 12-2.7432.689163YesYes
MED28 80306 6-2.4042.44586Yes-
TIA1 7072 4-1.2342.26353--
CBLL1 79872 6-1.8972.44538--
MED13L 23389 8-2.5502.30750Yes-
VARS 7407 8-2.3662.689204Yes-
POU5F1 5460 12-5.1483.538179YesYes
FBXO22 26263 8-1.7392.459208--
DENR 8562 4-1.0232.26342--
PSMD2 5708 6-4.1723.157389YesYes
FOXJ3 22887 4-2.4072.36987YesYes
EIF2S2 8894 9-2.9992.459103YesYes
SUV39H2 79723 7-2.3072.41021YesYes
CASP2 835 4-2.0072.44547Yes-
MED12 9968 2-2.4653.20665Yes-
ETF1 2107 7-2.8292.50377YesYes
GTF3C3 9330 4-1.4502.42862--
NAP1L4 4676 2-1.9473.119187--
CCT7 10574 10-2.3352.459173Yes-
CPSF3 51692 7-2.6862.50331YesYes
HNRNPU 3192 12-2.8692.644172Yes-
CLASP1 23332 4-2.3652.45939Yes-
NDUFA4L2 56901 10-2.4772.45921Yes-
HCFC1 3054 2-2.9253.44971YesYes
MED19 219541 4-2.6573.449115Yes-
AGPS 8540 6-2.4242.41027YesYes
SLC7A5P1 81893 4-3.2172.4454Yes-
YAP1 10413 12-4.2563.53853Yes-
NCBP1 4686 8-2.5102.45984YesYes
SYNCRIP 10492 8-2.4012.503247YesYes
LUC7L3 51747 4-3.5233.44918Yes-
ZDHHC20 253832 4-2.6732.32625Yes-
TADA2B 93624 4-3.0613.08219Yes-
FTSJ1 24140 5-2.4632.689130YesYes
EIF2B2 8892 4-2.4622.96895YesYes
GSPT1 2935 7-2.3132.50347YesYes
SRSF3 6428 5-2.9923.53854Yes-
NOLC1 9221 5-1.9852.503136--
POLH 5429 8-2.5862.45924YesYes
BTRC 8945 4-1.1442.26364--
DDIT3 1649 11-2.8253.504343YesYes
FUBP1 8880 6-2.4142.38941YesYes

Interactions (75)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
DENR 8562 CBLL1 79872 pd < reg.ITFP.txt: no annot
BTRC 8945 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
TIA1 7072 CLASP1 23332 pd <> reg.ITFP.txt: no annot
EIF2B2 8892 TADA2B 93624 pp -- int.I2D: BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly, MINT_Fly
ETF1 2107 GSPT1 2935 pp -- int.I2D: MINT, BCI, BioGrid, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
CCNC 892 NAP1L4 4676 pp -- int.I2D: BioGrid_Yeast
HNRNPU 3192 ANAPC5 51433 pd < reg.ITFP.txt: no annot
HCFC1 3054 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
DDIT3 1649 NAP1L4 4676 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
PSMD2 5708 CNOT1 23019 pp -- int.I2D: YeastLow
DENR 8562 FBXO22 26263 pd < reg.ITFP.txt: no annot
CNOT1 23019 ANAPC5 51433 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
NOLC1 9221 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
DENR 8562 ANAPC5 51433 pd < reg.ITFP.txt: no annot
NCBP1 4686 CBLL1 79872 pd < reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
DENR 8562 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
DENR 8562 GTF3C3 9330 pd < reg.ITFP.txt: no annot
CBLL1 79872 MED28 80306 pd > reg.ITFP.txt: no annot
MED12 9968 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
CCNC 892 MED12 9968 pp -- int.I2D: BioGrid
DDIT3 1649 HNRNPU 3192 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
MED12 9968 MED28 80306 pp -- int.I2D: BioGrid
LUC7L3 51747 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
HCFC1 3054 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
CCNC 892 MED13L 23389 pp -- int.I2D: IntAct_Fly, MINT_Fly
HNRNPU 3192 BTRC 8945 pp -- int.I2D: BCI, BioGrid, INNATEDB, HPRD;
int.HPRD: in vivo
PSMD2 5708 VARS 7407 pp -- int.I2D: BioGrid_Yeast
BTRC 8945 ZDHHC20 253832 pd > reg.ITFP.txt: no annot
POU5F1 5460 SRSF3 6428 pp -- int.I2D: BioGrid
NAP1L4 4676 FOXJ3 22887 pd < reg.ITFP.txt: no annot
DDIT3 1649 VARS 7407 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
MED28 80306 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
MED13L 23389 MED28 80306 pp -- int.I2D: BioGrid
CASP2 835 DENR 8562 pd > reg.ITFP.txt: no annot
ETF1 2107 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, YeastLow
YAP1 10413 MED28 80306 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
BTRC 8945 CNOT1 23019 pd > reg.ITFP.txt: no annot
PSMD2 5708 CCT7 10574 pp -- int.I2D: BioGrid_Yeast
CCNC 892 EIF2B2 8892 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
DENR 8562 NOLC1 9221 pd < reg.ITFP.txt: no annot
EIF2B2 8892 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot
SRSF3 6428 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
EIF2S2 8894 GTF3C3 9330 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
MED13L 23389 ANAPC5 51433 pd < reg.ITFP.txt: no annot
CCNC 892 MED28 80306 pp -- int.I2D: BioGrid
PSMD2 5708 EIF2B2 8892 pp -- int.I2D: IntAct_Yeast
TIA1 7072 DENR 8562 pd > reg.ITFP.txt: no annot
CCNC 892 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
CASP2 835 SLC7A5P1 81893 pd > reg.ITFP.txt: no annot
MED13L 23389 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
CASP2 835 CBLL1 79872 pd <> reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
GSPT1 2935 NOLC1 9221 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
CCNC 892 CNOT1 23019 pp -- int.I2D: BioGrid_Yeast
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 SYNCRIP 10492 pp -- int.Mint: MI:0915(physical association)
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
FUBP1 8880 ANAPC5 51433 pd <> reg.ITFP.txt: no annot
ANAPC5 51433 MED19 219541 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
DENR 8562 BTRC 8945 pd < reg.ITFP.txt: no annot
BTRC 8945 YAP1 10413 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)

Related GO terms (426)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0010467gene expression1.70e-092.77e-052.9241427669
GO:0005654nucleoplasm1.53e-082.50e-042.40616311095
GO:0016592mediator complex3.87e-086.31e-045.6955535
GO:0044822poly(A) RNA binding6.66e-071.09e-022.23614271078
GO:0005515protein binding1.12e-061.83e-020.96633776127
GO:0006366transcription from RNA polymerase II promoter1.83e-052.99e-012.771814425
GO:0008380RNA splicing3.96e-056.47e-013.230614232
GO:0003747translation release factor activity4.44e-057.25e-017.503224
GO:0003723RNA binding4.84e-057.89e-012.838715355
GO:0070461SAGA-type complex7.39e-051.00e+007.181225
GO:0070934CRD-mediated mRNA stabilization7.39e-051.00e+007.181225
GO:0000398mRNA splicing, via spliceosome8.76e-051.00e+003.45859165
GO:0001104RNA polymerase II transcription cofactor activity1.01e-041.00e+005.0433333
GO:0070937CRD-mediated mRNA stability complex1.11e-041.00e+006.918226
GO:0031124mRNA 3'-end processing2.09e-041.00e+004.6953442
GO:0006369termination of RNA polymerase II transcription2.56e-041.00e+004.5963445
GO:0030529ribonucleoprotein complex2.70e-041.00e+003.67046114
GO:0006379mRNA cleavage3.30e-041.00e+006.1812210
GO:0003743translation initiation factor activity3.30e-041.00e+004.4733549
GO:0008143poly(A) binding4.82e-041.00e+005.9182212
GO:0042789mRNA transcription from RNA polymerase II promoter5.69e-041.00e+005.8022213
GO:0006406mRNA export from nucleus6.61e-041.00e+004.1333562
GO:0006479protein methylation7.63e-041.00e+005.5962215
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle9.42e-041.00e+003.9583470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.11e-031.00e+003.8783474
GO:0044212transcription regulatory region DNA binding1.24e-031.00e+003.08545171
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.34e-031.00e+003.7843479
GO:0014003oligodendrocyte development1.37e-031.00e+005.1812320
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription1.66e-031.00e+005.0432222
GO:0016020membrane2.15e-031.00e+001.31812271746
GO:0001649osteoblast differentiation2.27e-031.00e+003.5183395
GO:0031047gene silencing by RNA2.32e-031.00e+004.8022226
GO:0005829cytosol2.64e-031.00e+001.08615382562
GO:0002128tRNA nucleoside ribose methylation2.76e-031.00e+008.503111
GO:2000016negative regulation of determination of dorsal identity2.76e-031.00e+008.503111
GO:0008609alkylglycerone-phosphate synthase activity2.76e-031.00e+008.503111
GO:0090308regulation of methylation-dependent chromatin silencing2.76e-031.00e+008.503111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway2.76e-031.00e+008.503111
GO:0060795cell fate commitment involved in formation of primary germ layer2.76e-031.00e+008.503111
GO:0031592centrosomal corona2.76e-031.00e+008.503111
GO:0097165nuclear stress granule2.76e-031.00e+008.503111
GO:0008079translation termination factor activity2.76e-031.00e+008.503111
GO:0016071mRNA metabolic process3.26e-031.00e+002.70248223
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.80e-031.00e+003.25533114
GO:0000209protein polyubiquitination3.99e-031.00e+003.23035116
GO:0006446regulation of translational initiation4.41e-031.00e+004.3332236
GO:0016070RNA metabolic process4.69e-031.00e+002.55448247
GO:0004832valine-tRNA ligase activity5.51e-031.00e+007.503112
GO:0060242contact inhibition5.51e-031.00e+007.503112
GO:0008175tRNA methyltransferase activity5.51e-031.00e+007.503112
GO:0019046release from viral latency5.51e-031.00e+007.503112
GO:0005846nuclear cap binding complex5.51e-031.00e+007.503112
GO:0002176male germ cell proliferation5.51e-031.00e+007.503112
GO:0045309protein phosphorylated amino acid binding5.51e-031.00e+007.503112
GO:0006438valyl-tRNA aminoacylation5.51e-031.00e+007.503112
GO:0009786regulation of asymmetric cell division5.51e-031.00e+007.503112
GO:0001554luteolysis5.51e-031.00e+007.503112
GO:0060965negative regulation of gene silencing by miRNA5.51e-031.00e+007.503112
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress5.51e-031.00e+007.503112
GO:0031111negative regulation of microtubule polymerization or depolymerization5.51e-031.00e+007.503112
GO:0030981cortical microtubule cytoskeleton5.51e-031.00e+007.503112
GO:0051294establishment of spindle orientation5.51e-031.00e+007.503112
GO:0044324regulation of transcription involved in anterior/posterior axis specification5.51e-031.00e+007.503112
GO:0017148negative regulation of translation5.69e-031.00e+004.1452341
GO:0043525positive regulation of neuron apoptotic process7.12e-031.00e+003.9792246
GO:0048511rhythmic process7.43e-031.00e+003.9482247
GO:0019827stem cell maintenance7.74e-031.00e+003.9182248
GO:0036123histone H3-K9 dimethylation8.25e-031.00e+006.918113
GO:0090245axis elongation involved in somitogenesis8.25e-031.00e+006.918113
GO:0005850eukaryotic translation initiation factor 2 complex8.25e-031.00e+006.918123
GO:0016149translation release factor activity, codon specific8.25e-031.00e+006.918113
GO:0003130BMP signaling pathway involved in heart induction8.25e-031.00e+006.918113
GO:0005778peroxisomal membrane8.37e-031.00e+003.8592250
GO:0006355regulation of transcription, DNA-templated9.80e-031.00e+001.3948131104
GO:0014044Schwann cell development1.10e-021.00e+006.503114
GO:0051716cellular response to stimulus1.10e-021.00e+006.503124
GO:0042036negative regulation of cytokine biosynthetic process1.10e-021.00e+006.503114
GO:0097452GAIT complex1.10e-021.00e+006.503124
GO:0060913cardiac cell fate determination1.10e-021.00e+006.503114
GO:0007000nucleolus organization1.10e-021.00e+006.503114
GO:0008611ether lipid biosynthetic process1.10e-021.00e+006.503114
GO:0051151negative regulation of smooth muscle cell differentiation1.10e-021.00e+006.503114
GO:0046523S-methyl-5-thioribose-1-phosphate isomerase activity1.10e-021.00e+006.503114
GO:0006290pyrimidine dimer repair1.10e-021.00e+006.503114
GO:0043515kinetochore binding1.10e-021.00e+006.503114
GO:0002192IRES-dependent translational initiation1.10e-021.00e+006.503114
GO:0044267cellular protein metabolic process1.13e-021.00e+001.87357495
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.15e-021.00e+003.6202259
GO:0006396RNA processing1.19e-021.00e+003.5962460
GO:0008013beta-catenin binding1.19e-021.00e+003.5962460
GO:0003682chromatin binding1.33e-021.00e+002.11947334
GO:0001714endodermal cell fate specification1.37e-021.00e+006.181115
GO:0003407neural retina development1.37e-021.00e+006.181115
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process1.37e-021.00e+006.181115
GO:0005828kinetochore microtubule1.37e-021.00e+006.181115
GO:0043620regulation of DNA-templated transcription in response to stress1.37e-021.00e+006.181115
GO:0010606positive regulation of cytoplasmic mRNA processing body assembly1.37e-021.00e+006.181115
GO:0031023microtubule organizing center organization1.37e-021.00e+006.181115
GO:0048742regulation of skeletal muscle fiber development1.37e-021.00e+006.181115
GO:0006398histone mRNA 3'-end processing1.37e-021.00e+006.181115
GO:0045292mRNA cis splicing, via spliceosome1.37e-021.00e+006.181115
GO:0031442positive regulation of mRNA 3'-end processing1.37e-021.00e+006.181115
GO:0006449regulation of translational termination1.37e-021.00e+006.181115
GO:0036124histone H3-K9 trimethylation1.37e-021.00e+006.181115
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.38e-021.00e+003.4802365
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.38e-021.00e+003.4802365
GO:0006367transcription initiation from RNA polymerase II promoter1.41e-021.00e+002.56435184
GO:0008762UDP-N-acetylmuramate dehydrogenase activity1.64e-021.00e+005.918116
GO:0042797tRNA transcription from RNA polymerase III promoter1.64e-021.00e+005.918126
GO:0050847progesterone receptor signaling pathway1.64e-021.00e+005.918116
GO:0002181cytoplasmic translation1.64e-021.00e+005.918116
GO:0046974histone methyltransferase activity (H3-K9 specific)1.64e-021.00e+005.918116
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.64e-021.00e+005.918116
GO:0048024regulation of mRNA splicing, via spliceosome1.64e-021.00e+005.918116
GO:0005851eukaryotic translation initiation factor 2B complex1.64e-021.00e+005.918136
GO:0000127transcription factor TFIIIC complex1.64e-021.00e+005.918126
GO:00427915S class rRNA transcription from RNA polymerase III type 1 promoter1.64e-021.00e+005.918126
GO:0006333chromatin assembly or disassembly1.64e-021.00e+005.918116
GO:0071204histone pre-mRNA 3'end processing complex1.64e-021.00e+005.918116
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.86e-021.00e+003.2552276
GO:0032790ribosome disassembly1.91e-021.00e+005.695117
GO:0002161aminoacyl-tRNA editing activity1.91e-021.00e+005.695117
GO:0042753positive regulation of circadian rhythm1.91e-021.00e+005.695117
GO:0004521endoribonuclease activity1.91e-021.00e+005.695117
GO:0010458exit from mitosis1.91e-021.00e+005.695117
GO:0006301postreplication repair1.91e-021.00e+005.695117
GO:0006282regulation of DNA repair1.91e-021.00e+005.695117
GO:0035234ectopic germ cell programmed cell death1.91e-021.00e+005.695117
GO:0071013catalytic step 2 spliceosome2.00e-021.00e+003.1992379
GO:0042754negative regulation of circadian rhythm2.19e-021.00e+005.503118
GO:0001955blood vessel maturation2.19e-021.00e+005.503118
GO:0000339RNA cap binding2.19e-021.00e+005.503118
GO:0070688MLL5-L complex2.19e-021.00e+005.503118
GO:0043254regulation of protein complex assembly2.19e-021.00e+005.503118
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.31e-021.00e+001.424613811
GO:0005739mitochondrion2.33e-021.00e+001.2797161046
GO:0000278mitotic cell cycle2.36e-021.00e+001.866412398
GO:0006415translational termination2.40e-021.00e+003.0602287
GO:0071354cellular response to interleukin-62.45e-021.00e+005.333119
GO:00084095'-3' exonuclease activity2.45e-021.00e+005.333119
GO:0016591DNA-directed RNA polymerase II, holoenzyme2.45e-021.00e+005.333119
GO:0043996histone acetyltransferase activity (H4-K8 specific)2.45e-021.00e+005.333119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.45e-021.00e+005.333119
GO:0043995histone acetyltransferase activity (H4-K5 specific)2.45e-021.00e+005.333119
GO:0033598mammary gland epithelial cell proliferation2.45e-021.00e+005.333119
GO:0046972histone acetyltransferase activity (H4-K16 specific)2.45e-021.00e+005.333119
GO:0019509L-methionine biosynthetic process from methylthioadenosine2.45e-021.00e+005.333119
GO:0048188Set1C/COMPASS complex2.45e-021.00e+005.333119
GO:0006983ER overload response2.45e-021.00e+005.333119
GO:0005832chaperonin-containing T-complex2.45e-021.00e+005.333119
GO:0006412translation2.68e-021.00e+002.21135235
GO:0008610lipid biosynthetic process2.72e-021.00e+005.1811110
GO:0002199zona pellucida receptor complex2.72e-021.00e+005.1811110
GO:0006450regulation of translational fidelity2.72e-021.00e+005.1811110
GO:0071949FAD binding2.72e-021.00e+005.1811110
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay2.72e-021.00e+005.1811110
GO:0010225response to UV-C2.72e-021.00e+005.1811210
GO:0000731DNA synthesis involved in DNA repair2.72e-021.00e+005.1811110
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway2.72e-021.00e+005.1811210
GO:0010944negative regulation of transcription by competitive promoter binding2.72e-021.00e+005.1811110
GO:0003713transcription coactivator activity2.80e-021.00e+002.18737239
GO:0051082unfolded protein binding2.82e-021.00e+002.9332395
GO:0045892negative regulation of transcription, DNA-templated2.90e-021.00e+001.77547424
GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling2.99e-021.00e+005.0431111
GO:0005845mRNA cap binding complex2.99e-021.00e+005.0431111
GO:0051010microtubule plus-end binding2.99e-021.00e+005.0431211
GO:0060071Wnt signaling pathway, planar cell polarity pathway2.99e-021.00e+005.0431111
GO:0048387negative regulation of retinoic acid receptor signaling pathway2.99e-021.00e+005.0431111
GO:0045662negative regulation of myoblast differentiation2.99e-021.00e+005.0431111
GO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening2.99e-021.00e+005.0431111
GO:0035413positive regulation of catenin import into nucleus2.99e-021.00e+005.0431111
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.99e-021.00e+005.0431111
GO:0004535poly(A)-specific ribonuclease activity2.99e-021.00e+005.0431111
GO:2000036regulation of stem cell maintenance2.99e-021.00e+005.0431111
GO:0060391positive regulation of SMAD protein import into nucleus2.99e-021.00e+005.0431111
GO:0034453microtubule anchoring3.26e-021.00e+004.9181112
GO:0061136regulation of proteasomal protein catabolic process3.26e-021.00e+004.9181112
GO:0008334histone mRNA metabolic process3.26e-021.00e+004.9181112
GO:0005838proteasome regulatory particle3.26e-021.00e+004.9181112
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process3.26e-021.00e+004.9181112
GO:0004842ubiquitin-protein transferase activity3.34e-021.00e+002.08835256
GO:0007140male meiosis3.53e-021.00e+004.8021113
GO:0042974retinoic acid receptor binding3.53e-021.00e+004.8021113
GO:0060766negative regulation of androgen receptor signaling pathway3.53e-021.00e+004.8021113
GO:0030914STAGA complex3.53e-021.00e+004.8021113
GO:0030234enzyme regulator activity3.53e-021.00e+004.8021113
GO:0060444branching involved in mammary gland duct morphogenesis3.53e-021.00e+004.8021113
GO:0035198miRNA binding3.53e-021.00e+004.8021113
GO:0030518intracellular steroid hormone receptor signaling pathway3.79e-021.00e+004.6951114
GO:0071480cellular response to gamma radiation3.79e-021.00e+004.6951114
GO:0005685U1 snRNP3.79e-021.00e+004.6951114
GO:0007020microtubule nucleation3.79e-021.00e+004.6951114
GO:0045807positive regulation of endocytosis3.79e-021.00e+004.6951114
GO:0000166nucleotide binding3.89e-021.00e+002.00036272
GO:0042809vitamin D receptor binding4.06e-021.00e+004.5961115
GO:0043981histone H4-K5 acetylation4.06e-021.00e+004.5961115
GO:0017091AU-rich element binding4.06e-021.00e+004.5961215
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex4.06e-021.00e+004.5961115
GO:0001824blastocyst development4.06e-021.00e+004.5961115
GO:0043982histone H4-K8 acetylation4.06e-021.00e+004.5961115
GO:0030014CCR4-NOT complex4.06e-021.00e+004.5961115
GO:0006376mRNA splice site selection4.06e-021.00e+004.5961115
GO:0007026negative regulation of microtubule depolymerization4.32e-021.00e+004.5031216
GO:0042176regulation of protein catabolic process4.32e-021.00e+004.5031116
GO:0001190RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription4.32e-021.00e+004.5031116
GO:0045893positive regulation of transcription, DNA-templated4.46e-021.00e+001.57546487
GO:0006325chromatin organization4.52e-021.00e+002.56023123
GO:0001829trophectodermal cell differentiation4.59e-021.00e+004.4151217
GO:0043274phospholipase binding4.59e-021.00e+004.4151117
GO:0001731formation of translation preinitiation complex4.59e-021.00e+004.4151117
GO:0016409palmitoyltransferase activity4.59e-021.00e+004.4151117
GO:0022624proteasome accessory complex4.59e-021.00e+004.4151117
GO:0006511ubiquitin-dependent protein catabolic process4.79e-021.00e+002.51423127
GO:0005634nucleus4.80e-021.00e+000.51319554828
GO:0006413translational initiation5.06e-021.00e+002.46924131
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process5.11e-021.00e+004.2551119
GO:0043984histone H4-K16 acetylation5.11e-021.00e+004.2551119
GO:0001578microtubule bundle formation5.38e-021.00e+004.1811120
GO:0003700sequence-specific DNA binding transcription factor activity5.38e-021.00e+001.278510748
GO:0097194execution phase of apoptosis5.38e-021.00e+004.1811120
GO:0005680anaphase-promoting complex5.38e-021.00e+004.1811120
GO:0018345protein palmitoylation5.38e-021.00e+004.1811120
GO:0000086G2/M transition of mitotic cell cycle5.48e-021.00e+002.40523137
GO:0045862positive regulation of proteolysis5.64e-021.00e+004.1101221
GO:0032757positive regulation of interleukin-8 production5.64e-021.00e+004.1101121
GO:0031648protein destabilization5.64e-021.00e+004.1101221
GO:0000123histone acetyltransferase complex5.64e-021.00e+004.1101221
GO:0016575histone deacetylation5.64e-021.00e+004.1101121
GO:0016055Wnt signaling pathway5.76e-021.00e+002.36323141
GO:0005720nuclear heterochromatin5.90e-021.00e+004.0431122
GO:0006378mRNA polyadenylation5.90e-021.00e+004.0431222
GO:0036464cytoplasmic ribonucleoprotein granule5.90e-021.00e+004.0431122
GO:0016032viral process6.08e-021.00e+001.426416540
GO:0005525GTP binding6.15e-021.00e+001.73035328
GO:0071346cellular response to interferon-gamma6.16e-021.00e+003.9791223
GO:0034660ncRNA metabolic process6.16e-021.00e+003.9791123
GO:0019706protein-cysteine S-palmitoyltransferase activity6.16e-021.00e+003.9791123
GO:0045787positive regulation of cell cycle6.16e-021.00e+003.9791123
GO:0045879negative regulation of smoothened signaling pathway6.16e-021.00e+003.9791123
GO:0010628positive regulation of gene expression6.35e-021.00e+002.28322149
GO:0008135translation factor activity, nucleic acid binding6.42e-021.00e+003.9181224
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress6.42e-021.00e+003.9181124
GO:0007163establishment or maintenance of cell polarity6.42e-021.00e+003.9181124
GO:0000082G1/S transition of mitotic cell cycle6.43e-021.00e+002.27424150
GO:0042981regulation of apoptotic process6.50e-021.00e+002.26423151
GO:0030864cortical actin cytoskeleton6.67e-021.00e+003.8591125
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening6.67e-021.00e+003.8591125
GO:0035329hippo signaling6.93e-021.00e+003.8021126
GO:0070979protein K11-linked ubiquitination6.93e-021.00e+003.8021126
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic6.93e-021.00e+003.8021126
GO:0051209release of sequestered calcium ion into cytosol6.93e-021.00e+003.8021226
GO:0046966thyroid hormone receptor binding6.93e-021.00e+003.8021126
GO:0006974cellular response to DNA damage stimulus7.04e-021.00e+002.19924158
GO:0006913nucleocytoplasmic transport7.19e-021.00e+003.7481127
GO:0030331estrogen receptor binding7.19e-021.00e+003.7481227
GO:0000387spliceosomal snRNP assembly7.19e-021.00e+003.7481127
GO:0071339MLL1 complex7.19e-021.00e+003.7481127
GO:0007339binding of sperm to zona pellucida7.19e-021.00e+003.7481127
GO:2001235positive regulation of apoptotic signaling pathway7.45e-021.00e+003.6951128
GO:0000976transcription regulatory region sequence-specific DNA binding7.45e-021.00e+003.6951128
GO:0043022ribosome binding7.45e-021.00e+003.6951228
GO:0019005SCF ubiquitin ligase complex7.70e-021.00e+003.6451129
GO:0016485protein processing7.70e-021.00e+003.6451129
GO:0003887DNA-directed DNA polymerase activity7.70e-021.00e+003.6451129
GO:0071897DNA biosynthetic process7.70e-021.00e+003.6451129
GO:0000122negative regulation of transcription from RNA polymerase II promoter7.83e-021.00e+001.300410589
GO:0043565sequence-specific DNA binding7.91e-021.00e+001.57633365
GO:00063707-methylguanosine mRNA capping7.96e-021.00e+003.5961230
GO:0010494cytoplasmic stress granule7.96e-021.00e+003.5961230
GO:0007094mitotic spindle assembly checkpoint8.21e-021.00e+003.5481331
GO:0005782peroxisomal matrix8.21e-021.00e+003.5481131
GO:0016607nuclear speck8.39e-021.00e+002.05126175
GO:0042594response to starvation8.46e-021.00e+003.5031332
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic8.46e-021.00e+003.5031132
GO:1903507negative regulation of nucleic acid-templated transcription8.46e-021.00e+003.5031132
GO:0007049cell cycle8.55e-021.00e+002.03524177
GO:0007162negative regulation of cell adhesion8.72e-021.00e+003.4581133
GO:0003714transcription corepressor activity8.72e-021.00e+002.01925179
GO:0019904protein domain specific binding8.88e-021.00e+002.00322181
GO:0005876spindle microtubule8.97e-021.00e+003.4151134
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand9.22e-021.00e+003.3731135
GO:0009267cellular response to starvation9.47e-021.00e+003.3331136
GO:0042552myelination9.47e-021.00e+003.3331236
GO:0030178negative regulation of Wnt signaling pathway9.47e-021.00e+003.3331136
GO:0051084'de novo' posttranslational protein folding9.72e-021.00e+003.2931137
GO:0001541ovarian follicle development9.72e-021.00e+003.2931137
GO:0042752regulation of circadian rhythm9.72e-021.00e+003.2931337
GO:0006383transcription from RNA polymerase III promoter1.02e-011.00e+003.2171339
GO:0071407cellular response to organic cyclic compound1.02e-011.00e+003.2171339
GO:0009408response to heat1.05e-011.00e+003.1811240
GO:0035019somatic stem cell maintenance1.05e-011.00e+003.1811240
GO:0005881cytoplasmic microtubule1.07e-011.00e+003.1451241
GO:0030521androgen receptor signaling pathway1.07e-011.00e+003.1451141
GO:0006418tRNA aminoacylation for protein translation1.10e-011.00e+003.1101342
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity1.12e-011.00e+003.0761143
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.15e-011.00e+003.0431144
GO:0003712transcription cofactor activity1.15e-011.00e+003.0431144
GO:0050434positive regulation of viral transcription1.15e-011.00e+003.0431244
GO:0015030Cajal body1.17e-011.00e+003.0111145
GO:0044297cell body1.19e-011.00e+002.9791146
GO:0043434response to peptide hormone1.19e-011.00e+002.9791246
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.22e-011.00e+002.9481147
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage1.27e-011.00e+002.8881149
GO:0016874ligase activity1.27e-011.00e+001.69524224
GO:0006521regulation of cellular amino acid metabolic process1.29e-011.00e+002.8591250
GO:0006986response to unfolded protein1.32e-011.00e+002.8301251
GO:0003684damaged DNA binding1.32e-011.00e+002.8301151
GO:0007067mitotic nuclear division1.33e-011.00e+001.65124231
GO:0000775chromosome, centromeric region1.34e-011.00e+002.8021352
GO:0004197cysteine-type endopeptidase activity1.34e-011.00e+002.8021152
GO:0034976response to endoplasmic reticulum stress1.34e-011.00e+002.8021152
GO:0045454cell redox homeostasis1.34e-011.00e+002.8021152
GO:0009611response to wounding1.36e-011.00e+002.7751153
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1.36e-011.00e+002.7751253
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.39e-011.00e+002.7481154
GO:0000226microtubule cytoskeleton organization1.41e-011.00e+002.7211255
GO:0006351transcription, DNA-templated1.42e-011.00e+000.6807171585
GO:0000932cytoplasmic mRNA processing body1.43e-011.00e+002.6951256
GO:0008134transcription factor binding1.47e-011.00e+001.56026246
GO:0000502proteasome complex1.48e-011.00e+002.6451258
GO:0042802identical protein binding1.53e-011.00e+001.14836491
GO:0006987activation of signaling protein activity involved in unfolded protein response1.58e-011.00e+002.5481262
GO:0000151ubiquitin ligase complex1.60e-011.00e+002.5251263
GO:0019903protein phosphatase binding1.60e-011.00e+002.5251163
GO:0000776kinetochore1.60e-011.00e+002.5251463
GO:0006417regulation of translation1.60e-011.00e+002.5251163
GO:0009749response to glucose1.62e-011.00e+002.5031264
GO:0003677DNA binding1.65e-011.00e+000.6886161351
GO:0071260cellular response to mechanical stimulus1.67e-011.00e+002.4581166
GO:0006368transcription elongation from RNA polymerase II promoter1.69e-011.00e+002.4361367
GO:0006338chromatin remodeling1.71e-011.00e+002.4151168
GO:0000777condensed chromosome kinetochore1.71e-011.00e+002.4151168
GO:0003697single-stranded DNA binding1.74e-011.00e+002.3941269
GO:0006357regulation of transcription from RNA polymerase II promoter1.75e-011.00e+001.39924275
GO:0005730nucleolus1.77e-011.00e+000.5927281684
GO:0010468regulation of gene expression1.81e-011.00e+002.3331172
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.83e-011.00e+002.3131273
GO:0003729mRNA binding1.83e-011.00e+002.3131373
GO:0000785chromatin1.83e-011.00e+002.3131273
GO:0005085guanyl-nucleotide exchange factor activity1.85e-011.00e+002.2931274
GO:0042826histone deacetylase binding1.85e-011.00e+002.2931274
GO:0060070canonical Wnt signaling pathway1.87e-011.00e+002.2741275
GO:0001843neural tube closure1.87e-011.00e+002.2741175
GO:0019899enzyme binding1.88e-011.00e+001.33323288
GO:0008584male gonad development1.92e-011.00e+002.2361177
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.92e-011.00e+002.2361277
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity1.92e-011.00e+002.2361277
GO:0006334nucleosome assembly1.96e-011.00e+002.1991379
GO:0016567protein ubiquitination1.99e-011.00e+001.27925299
GO:0030968endoplasmic reticulum unfolded protein response2.01e-011.00e+002.1631281
GO:0051301cell division2.01e-011.00e+002.1631281
GO:0006915apoptotic process2.08e-011.00e+000.93038571
GO:0009653anatomical structure morphogenesis2.14e-011.00e+002.0601187
GO:0090090negative regulation of canonical Wnt signaling pathway2.16e-011.00e+002.0431488
GO:0006464cellular protein modification process2.18e-011.00e+002.0271189
GO:0005777peroxisome2.21e-011.00e+002.0111190
GO:0050821protein stabilization2.23e-011.00e+001.9951391
GO:0016337single organismal cell-cell adhesion2.25e-011.00e+001.9791192
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.29e-011.00e+001.9481294
GO:0005770late endosome2.29e-011.00e+001.9481194
GO:0006364rRNA processing2.33e-011.00e+001.9181296
GO:0030018Z disc2.38e-011.00e+001.8881298
GO:0071456cellular response to hypoxia2.38e-011.00e+001.8881298
GO:0006470protein dephosphorylation2.40e-011.00e+001.8731199
GO:0007417central nervous system development2.44e-011.00e+001.84412101
GO:0051726regulation of cell cycle2.46e-011.00e+001.83014102
GO:0005938cell cortex2.61e-011.00e+001.73411109
GO:0030308negative regulation of cell growth2.69e-011.00e+001.68212113
GO:0097190apoptotic signaling pathway2.75e-011.00e+001.64511116
GO:0005737cytoplasm2.89e-011.00e+000.24613433976
GO:0007568aging2.89e-011.00e+001.56012123
GO:0007219Notch signaling pathway2.93e-011.00e+001.53712125
GO:0006260DNA replication2.93e-011.00e+001.53714125
GO:0007050cell cycle arrest2.95e-011.00e+001.52513126
GO:0007179transforming growth factor beta receptor signaling pathway3.03e-011.00e+001.48011130
GO:0030335positive regulation of cell migration3.03e-011.00e+001.48012130
GO:0046983protein dimerization activity3.05e-011.00e+001.46911131
GO:0005524ATP binding3.17e-011.00e+000.4225131354
GO:0044255cellular lipid metabolic process3.22e-011.00e+001.37311140
GO:0007507heart development3.24e-011.00e+001.36312141
GO:0008270zinc ion binding3.39e-011.00e+000.4434111067
GO:0006457protein folding3.39e-011.00e+001.28311149
GO:0008017microtubule binding3.40e-011.00e+001.27414150
GO:0008022protein C-terminus binding3.60e-011.00e+001.17211161
GO:0007420brain development3.80e-011.00e+001.07611172
GO:0034641cellular nitrogen compound metabolic process3.88e-011.00e+001.03513177
GO:0005667transcription factor complex3.90e-011.00e+001.02713178
GO:0031625ubiquitin protein ligase binding3.93e-011.00e+001.01112180
GO:0043547positive regulation of GTPase activity4.10e-011.00e+000.93312190
GO:0004872receptor activity4.25e-011.00e+000.86611199
GO:0003924GTPase activity4.31e-011.00e+000.83712203
GO:0001701in utero embryonic development4.42e-011.00e+000.78812210
GO:0006184GTP catabolic process4.57e-011.00e+000.72112220
GO:0005622intracellular4.67e-011.00e+000.68212226
GO:0043025neuronal cell body5.07e-011.00e+000.51413254
GO:0005874microtubule5.12e-011.00e+000.49113258
GO:0006281DNA repair5.20e-011.00e+000.45814264
GO:0048011neurotrophin TRK receptor signaling pathway5.32e-011.00e+000.41012273
GO:0043065positive regulation of apoptotic process5.34e-011.00e+000.40513274
GO:0003779actin binding5.35e-011.00e+000.39911275
GO:0005743mitochondrial inner membrane5.67e-011.00e+000.27413300
GO:0019901protein kinase binding5.90e-011.00e+000.18114320
GO:0005575cellular_component5.93e-011.00e+000.17211322
GO:0030154cell differentiation5.96e-011.00e+000.15812325
GO:0007411axon guidance5.98e-011.00e+000.14912327
GO:0008283cell proliferation6.03e-011.00e+000.13213331
GO:0043231intracellular membrane-bounded organelle6.04e-011.00e+000.12811332
GO:0005813centrosome6.12e-011.00e+000.09714339
GO:0008285negative regulation of cell proliferation6.41e-011.00e+00-0.01714367
GO:0005925focal adhesion6.44e-011.00e+00-0.02912370
GO:0046982protein heterodimerization activity6.72e-011.00e+00-0.13813399
GO:0006508proteolysis6.82e-011.00e+00-0.17712410
GO:0009986cell surface6.93e-011.00e+00-0.21914422
GO:0043066negative regulation of apoptotic process7.02e-011.00e+00-0.25615433
GO:0055114oxidation-reduction process7.40e-011.00e+00-0.40712481
GO:0007165signal transduction7.46e-011.00e+00-0.38928950
GO:0003674molecular_function7.70e-011.00e+00-0.53111524
GO:0046872metal ion binding7.82e-011.00e+00-0.429361465
GO:0005783endoplasmic reticulum8.20e-011.00e+00-0.75012610
GO:0005794Golgi apparatus8.40e-011.00e+00-0.84211650
GO:0044281small molecule metabolic process8.82e-011.00e+00-0.8362121295
GO:0070062extracellular vesicular exosome9.32e-011.00e+00-0.7944152516
GO:0005887integral component of plasma membrane9.35e-011.00e+00-1.40611961
GO:0005615extracellular space9.44e-011.00e+00-1.478141010
GO:0005886plasma membrane9.90e-011.00e+00-1.3813142834
GO:0016021integral component of membrane9.99e-011.00e+00-2.775172483