meta-int-snw-1029

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-80153 chia-screen-data-Fav 2.203 2.78e-07 4.60e-02 3.49e-02 32 22
int-snw-1029 chia-screen-data-Fav 2.959 7.22e-17 1.01e-04 1.12e-03 11 10
reg-snw-8562 chia-screen-data-Fav 2.263 1.35e-07 3.15e-02 2.44e-02 32 24
chia-screen-data-Fav-meta-int-snw-1029 subnetwork

Genes (54)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
ANAPC5 51433 6-1.2642.263239TF--
CNOT1 23019 7-2.3472.263124-Yes-
CHERP 10523 2-1.6322.203210TF--
RAE1 8480 2-1.5012.342204TF--
PHB 5245 12-2.7432.689163-YesYes
RASSF7 8045 2-1.5182.20349TF--
MED28 80306 6-2.4042.44586-Yes-
TIA1 7072 4-1.2342.26353TF--
CBLL1 79872 6-1.8972.44538TF--
MED13L 23389 8-2.5502.30750-Yes-
VARS 7407 8-2.3662.689204TFYes-
POU5F1 5460 12-5.1483.538179-YesYes
FBXO22 26263 8-1.7392.459208TF--
EDC3 80153 2-0.9432.20342---
E4F1 1877 3-2.3702.95927-YesYes
DENR 8562 4-1.0232.26342---
RNF40 9810 2-2.0822.49263TFYes-
FOXJ3 22887 4-2.4072.36987TFYesYes
EIF2S2 8894 9-2.9992.459103-YesYes
FBXL6 26233 5-2.2532.68922-Yes-
SUV39H2 79723 7-2.3072.41021-YesYes
BEST1 7439 2-2.2502.28119-Yes-
KLC3 147700 2-2.1302.290132TFYes-
CASP2 835 4-2.0072.44547TFYes-
ETF1 2107 7-2.8292.50377-YesYes
GTF3C3 9330 4-1.4502.42862TF--
CCT7 10574 10-2.3352.459173-Yes-
CPSF3 51692 7-2.6862.50331-YesYes
HNRNPU 3192 12-2.8692.644172-Yes-
DRG2 1819 2-2.5262.49211-Yes-
CLASP1 23332 4-2.3652.45939TFYes-
NDUFA4L2 56901 10-2.4772.45921-Yes-
GTF3C2 2976 2-1.2302.225179TF--
NONO 4841 2-1.2322.203223TF--
TMEM68 137695 2-1.5652.31297TF--
AGPS 8540 6-2.4242.41027-YesYes
SLC7A5P1 81893 4-3.2172.4454-Yes-
WDR18 57418 2-1.3212.225213TF--
YAP1 10413 12-4.2563.53853-Yes-
NCBP1 4686 8-2.5102.45984-YesYes
SYNCRIP 10492 8-2.4012.503247TFYesYes
ZDHHC20 253832 4-2.6732.32625-Yes-
FTSJ1 24140 5-2.4632.689130-YesYes
LCE1E 353135 2-2.4282.41431-YesYes
GSPT1 2935 7-2.3132.50347-YesYes
NFRKB 4798 3-3.1293.10833-YesYes
YY1 7528 3-2.5723.120168TFYesYes
GPS1 2873 10-3.6212.68962TFYesYes
NOLC1 9221 5-1.9852.503136TF--
POLH 5429 8-2.5862.45924-YesYes
BTRC 8945 4-1.1442.26364TF--
DDIT3 1649 11-2.8253.504343-YesYes
CDKN2A 1029 3-1.7742.959126---
FUBP1 8880 6-2.4142.38941TFYesYes

Interactions (108)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
DENR 8562 CBLL1 79872 pd < reg.ITFP.txt: no annot
BTRC 8945 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
RAE1 8480 FBXL6 26233 pd > reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
TIA1 7072 CLASP1 23332 pd <> reg.ITFP.txt: no annot
CHERP 10523 KLC3 147700 pd <> reg.ITFP.txt: no annot
GTF3C2 2976 GTF3C3 9330 pp -- int.I2D: BioGrid
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
RASSF7 8045 EDC3 80153 pd > reg.ITFP.txt: no annot
ETF1 2107 GSPT1 2935 pp -- int.I2D: MINT, BCI, BioGrid, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
CDKN2A 1029 HNRNPU 3192 pp -- int.Intact: MI:0915(physical association)
GTF3C2 2976 EDC3 80153 pd > reg.ITFP.txt: no annot
NONO 4841 ANAPC5 51433 pd <> reg.ITFP.txt: no annot
HNRNPU 3192 ANAPC5 51433 pd < reg.ITFP.txt: no annot
WDR18 57418 EDC3 80153 pd > reg.ITFP.txt: no annot
VARS 7407 WDR18 57418 pd <> reg.ITFP.txt: no annot
DENR 8562 FBXO22 26263 pd < reg.ITFP.txt: no annot
CNOT1 23019 ANAPC5 51433 pd < reg.ITFP.txt: no annot
NOLC1 9221 WDR18 57418 pd <> reg.ITFP.txt: no annot
SUV39H2 79723 TMEM68 137695 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
GTF3C2 2976 NOLC1 9221 pd <> reg.ITFP.txt: no annot
RAE1 8480 EDC3 80153 pd > reg.ITFP.txt: no annot
DDIT3 1649 NONO 4841 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
NFRKB 4798 NONO 4841 pd < reg.ITFP.txt: no annot
NFRKB 4798 YY1 7528 pp -- int.I2D: BioGrid
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
CDKN2A 1029 FTSJ1 24140 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
DENR 8562 ANAPC5 51433 pd < reg.ITFP.txt: no annot
NCBP1 4686 CBLL1 79872 pd < reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
DENR 8562 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
DENR 8562 GTF3C3 9330 pd < reg.ITFP.txt: no annot
RAE1 8480 NOLC1 9221 pd <> reg.ITFP.txt: no annot
RNF40 9810 EDC3 80153 pd > reg.ITFP.txt: no annot
CBLL1 79872 MED28 80306 pd > reg.ITFP.txt: no annot
CDKN2A 1029 GSPT1 2935 pp -- int.I2D: BCI;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
DRG2 1819 GTF3C2 2976 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 WDR18 57418 pd <> reg.ITFP.txt: no annot
FBXO22 26263 WDR18 57418 pd <> reg.ITFP.txt: no annot
FBXO22 26263 EDC3 80153 pd > reg.ITFP.txt: no annot
DDIT3 1649 HNRNPU 3192 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU 3192 BTRC 8945 pp -- int.I2D: BCI, BioGrid, INNATEDB, HPRD;
int.HPRD: in vivo
BTRC 8945 ZDHHC20 253832 pd > reg.ITFP.txt: no annot
NONO 4841 FTSJ1 24140 pd > reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
KLC3 147700 LCE1E 353135 pd > reg.ITFP.txt: no annot
DRG2 1819 NONO 4841 pd < reg.ITFP.txt: no annot
CHERP 10523 LCE1E 353135 pd > reg.ITFP.txt: no annot
DDIT3 1649 VARS 7407 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
MED13L 23389 MED28 80306 pp -- int.I2D: BioGrid
NONO 4841 EDC3 80153 pd > reg.ITFP.txt: no annot
CASP2 835 DENR 8562 pd > reg.ITFP.txt: no annot
NFRKB 4798 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
ETF1 2107 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast, YeastLow
GTF3C2 2976 WDR18 57418 pd <> reg.ITFP.txt: no annot
YAP1 10413 MED28 80306 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
GTF3C2 2976 RAE1 8480 pd <> reg.ITFP.txt: no annot
BTRC 8945 CNOT1 23019 pd > reg.ITFP.txt: no annot
CPSF3 51692 TMEM68 137695 pd < reg.ITFP.txt: no annot
RNF40 9810 KLC3 147700 pd <> reg.ITFP.txt: no annot
EDC3 80153 KLC3 147700 pd < reg.ITFP.txt: no annot
FBXL6 26233 WDR18 57418 pd < reg.ITFP.txt: no annot
DENR 8562 NOLC1 9221 pd < reg.ITFP.txt: no annot
BEST1 7439 CHERP 10523 pd < reg.ITFP.txt: no annot
CDKN2A 1029 E4F1 1877 pp -- int.I2D: BioGrid;
int.HPRD: in vivo
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot
CHERP 10523 EDC3 80153 pd > reg.ITFP.txt: no annot
GTF3C2 2976 NONO 4841 pd <> reg.ITFP.txt: no annot
GPS1 2873 WDR18 57418 pd <> reg.ITFP.txt: no annot
EIF2S2 8894 GTF3C3 9330 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
RASSF7 8045 CHERP 10523 pd <> reg.ITFP.txt: no annot
HNRNPU 3192 NONO 4841 pd < reg.ITFP.txt: no annot
MED13L 23389 ANAPC5 51433 pd < reg.ITFP.txt: no annot
NONO 4841 RAE1 8480 pd <> reg.ITFP.txt: no annot
NCBP1 4686 RNF40 9810 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, VidalHuman_core;
int.HPRD: yeast 2-hybrid
TIA1 7072 DENR 8562 pd > reg.ITFP.txt: no annot
PHB 5245 WDR18 57418 pd < reg.ITFP.txt: no annot
CDKN2A 1029 YY1 7528 pd < reg.TRANSFAC.txt: no annot
CDKN2A 1029 YY1 7528 pp -- int.I2D: BioGrid, BIND, BCI
CASP2 835 SLC7A5P1 81893 pd > reg.ITFP.txt: no annot
RASSF7 8045 KLC3 147700 pd <> reg.ITFP.txt: no annot
CASP2 835 CBLL1 79872 pd <> reg.ITFP.txt: no annot
GTF3C2 2976 CNOT1 23019 pd > reg.ITFP.txt: no annot
EDC3 80153 TMEM68 137695 pd < reg.ITFP.txt: no annot
RAE1 8480 GTF3C3 9330 pd <> reg.ITFP.txt: no annot
RAE1 8480 CPSF3 51692 pd > reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
GSPT1 2935 NOLC1 9221 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 SYNCRIP 10492 pp -- int.Mint: MI:0915(physical association)
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
RAE1 8480 WDR18 57418 pd <> reg.ITFP.txt: no annot
NOLC1 9221 EDC3 80153 pd > reg.ITFP.txt: no annot
FUBP1 8880 ANAPC5 51433 pd <> reg.ITFP.txt: no annot
NONO 4841 FBXO22 26263 pd <> reg.ITFP.txt: no annot
FTSJ1 24140 WDR18 57418 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
CCT7 10574 WDR18 57418 pd < reg.ITFP.txt: no annot
DENR 8562 BTRC 8945 pd < reg.ITFP.txt: no annot
BTRC 8945 YAP1 10413 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)

Related GO terms (471)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005654nucleoplasm1.65e-062.69e-022.05015311095
GO:0003723RNA binding2.21e-063.61e-022.938915355
GO:0044822poly(A) RNA binding7.40e-061.21e-011.97314271078
GO:0010467gene expression9.68e-061.58e-012.3131127669
GO:0005515protein binding4.31e-057.04e-010.78835776127
GO:0003747translation release factor activity6.42e-051.00e+007.240224
GO:0070934CRD-mediated mRNA stabilization1.07e-041.00e+006.918225
GO:0042797tRNA transcription from RNA polymerase III promoter1.60e-041.00e+006.655226
GO:0070937CRD-mediated mRNA stability complex1.60e-041.00e+006.655226
GO:0000127transcription factor TFIIIC complex1.60e-041.00e+006.655226
GO:00427915S class rRNA transcription from RNA polymerase III type 1 promoter1.60e-041.00e+006.655226
GO:0044212transcription regulatory region DNA binding2.49e-041.00e+003.14455171
GO:0016020membrane3.92e-041.00e+001.37715271746
GO:0006379mRNA cleavage4.75e-041.00e+005.9182210
GO:0010225response to UV-C4.75e-041.00e+005.9182210
GO:0030529ribonucleoprotein complex5.46e-041.00e+003.40746114
GO:0008143poly(A) binding6.94e-041.00e+005.6552212
GO:0042789mRNA transcription from RNA polymerase II promoter8.19e-041.00e+005.5392213
GO:0031011Ino80 complex9.53e-041.00e+005.4322214
GO:0008380RNA splicing9.97e-041.00e+002.704514232
GO:0006396RNA processing1.03e-031.00e+003.9183460
GO:0006479protein methylation1.10e-031.00e+005.3332215
GO:0006406mRNA export from nucleus1.13e-031.00e+003.8703562
GO:0004842ubiquitin-protein transferase activity1.54e-031.00e+002.56155256
GO:0000398mRNA splicing, via spliceosome2.15e-031.00e+002.87349165
GO:0031648protein destabilization2.17e-031.00e+004.8472221
GO:0045892negative regulation of transcription, DNA-templated2.67e-031.00e+002.09767424
GO:0006366transcription from RNA polymerase II promoter2.70e-031.00e+002.093614425
GO:0003714transcription corepressor activity2.89e-031.00e+002.75645179
GO:0002128tRNA nucleoside ribose methylation3.31e-031.00e+008.240111
GO:2000016negative regulation of determination of dorsal identity3.31e-031.00e+008.240111
GO:0008609alkylglycerone-phosphate synthase activity3.31e-031.00e+008.240111
GO:0090308regulation of methylation-dependent chromatin silencing3.31e-031.00e+008.240111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway3.31e-031.00e+008.240111
GO:0060795cell fate commitment involved in formation of primary germ layer3.31e-031.00e+008.240111
GO:0031592centrosomal corona3.31e-031.00e+008.240111
GO:0097165nuclear stress granule3.31e-031.00e+008.240111
GO:0008079translation termination factor activity3.31e-031.00e+008.240111
GO:0009794regulation of mitotic cell cycle, embryonic3.31e-031.00e+008.240111
GO:0031047gene silencing by RNA3.32e-031.00e+004.5392226
GO:0051209release of sequestered calcium ion into cytosol3.32e-031.00e+004.5392226
GO:0001649osteoblast differentiation3.82e-031.00e+003.2553395
GO:0016592mediator complex5.96e-031.00e+004.1102535
GO:0016071mRNA metabolic process6.29e-031.00e+002.43948223
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay6.36e-031.00e+002.99233114
GO:0016874ligase activity6.39e-031.00e+002.43244224
GO:0004832valine-tRNA ligase activity6.61e-031.00e+007.240112
GO:0060242contact inhibition6.61e-031.00e+007.240112
GO:0006403RNA localization6.61e-031.00e+007.240112
GO:0008175tRNA methyltransferase activity6.61e-031.00e+007.240112
GO:0005846nuclear cap binding complex6.61e-031.00e+007.240112
GO:0002176male germ cell proliferation6.61e-031.00e+007.240112
GO:0045309protein phosphorylated amino acid binding6.61e-031.00e+007.240112
GO:0006438valyl-tRNA aminoacylation6.61e-031.00e+007.240112
GO:0009786regulation of asymmetric cell division6.61e-031.00e+007.240112
GO:0001554luteolysis6.61e-031.00e+007.240112
GO:0055105ubiquitin-protein transferase inhibitor activity6.61e-031.00e+007.240112
GO:0060965negative regulation of gene silencing by miRNA6.61e-031.00e+007.240112
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress6.61e-031.00e+007.240112
GO:0031111negative regulation of microtubule polymerization or depolymerization6.61e-031.00e+007.240112
GO:0034696response to prostaglandin F6.61e-031.00e+007.240112
GO:0030981cortical microtubule cytoskeleton6.61e-031.00e+007.240112
GO:0051294establishment of spindle orientation6.61e-031.00e+007.240112
GO:0044324regulation of transcription involved in anterior/posterior axis specification6.61e-031.00e+007.240112
GO:0042752regulation of circadian rhythm6.64e-031.00e+004.0302337
GO:0000209protein polyubiquitination6.67e-031.00e+002.96735116
GO:0005829cytosol7.14e-031.00e+000.91616382562
GO:0006383transcription from RNA polymerase III promoter7.36e-031.00e+003.9542339
GO:0071407cellular response to organic cyclic compound7.36e-031.00e+003.9542339
GO:0017148negative regulation of translation8.11e-031.00e+003.8822341
GO:0031124mRNA 3'-end processing8.50e-031.00e+003.8472442
GO:0006511ubiquitin-dependent protein catabolic process8.55e-031.00e+002.83633127
GO:0016070RNA metabolic process8.96e-031.00e+002.29148247
GO:0006369termination of RNA polymerase II transcription9.71e-031.00e+003.7482445
GO:0036123histone H3-K9 dimethylation9.89e-031.00e+006.655113
GO:0035986senescence-associated heterochromatin focus assembly9.89e-031.00e+006.655113
GO:2000111positive regulation of macrophage apoptotic process9.89e-031.00e+006.655113
GO:0005850eukaryotic translation initiation factor 2 complex9.89e-031.00e+006.655123
GO:0016149translation release factor activity, codon specific9.89e-031.00e+006.655113
GO:0035985senescence-associated heterochromatin focus9.89e-031.00e+006.655113
GO:0003130BMP signaling pathway involved in heart induction9.89e-031.00e+006.655113
GO:0000278mitotic cell cycle9.99e-031.00e+001.925512398
GO:0043525positive regulation of neuron apoptotic process1.01e-021.00e+003.7162246
GO:0048511rhythmic process1.06e-021.00e+003.6852247
GO:0003743translation initiation factor activity1.14e-021.00e+003.6252549
GO:0005778peroxisomal membrane1.19e-021.00e+003.5962250
GO:2000774positive regulation of cellular senescence1.32e-021.00e+006.240114
GO:0042036negative regulation of cytokine biosynthetic process1.32e-021.00e+006.240114
GO:0097452GAIT complex1.32e-021.00e+006.240124
GO:0051533positive regulation of NFAT protein import into nucleus1.32e-021.00e+006.240114
GO:0060913cardiac cell fate determination1.32e-021.00e+006.240114
GO:0007000nucleolus organization1.32e-021.00e+006.240114
GO:0033503HULC complex1.32e-021.00e+006.240114
GO:0008611ether lipid biosynthetic process1.32e-021.00e+006.240114
GO:0051151negative regulation of smooth muscle cell differentiation1.32e-021.00e+006.240114
GO:1903377negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway1.32e-021.00e+006.240114
GO:0006290pyrimidine dimer repair1.32e-021.00e+006.240114
GO:0033088negative regulation of immature T cell proliferation in thymus1.32e-021.00e+006.240114
GO:0043515kinetochore binding1.32e-021.00e+006.240114
GO:0002192IRES-dependent translational initiation1.32e-021.00e+006.240114
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1.33e-021.00e+003.5122253
GO:0008017microtubule binding1.34e-021.00e+002.59634150
GO:0000932cytoplasmic mRNA processing body1.48e-021.00e+003.4322256
GO:0006974cellular response to DNA damage stimulus1.54e-021.00e+002.52134158
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.63e-021.00e+003.3572259
GO:0001714endodermal cell fate specification1.64e-021.00e+005.918115
GO:0003407neural retina development1.64e-021.00e+005.918115
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process1.64e-021.00e+005.918115
GO:0005828kinetochore microtubule1.64e-021.00e+005.918115
GO:0043620regulation of DNA-templated transcription in response to stress1.64e-021.00e+005.918115
GO:1902510regulation of apoptotic DNA fragmentation1.64e-021.00e+005.918115
GO:0030321transepithelial chloride transport1.64e-021.00e+005.918115
GO:0034393positive regulation of smooth muscle cell apoptotic process1.64e-021.00e+005.918115
GO:0010606positive regulation of cytoplasmic mRNA processing body assembly1.64e-021.00e+005.918115
GO:0031023microtubule organizing center organization1.64e-021.00e+005.918115
GO:0097371MDM2/MDM4 family protein binding1.64e-021.00e+005.918115
GO:0048742regulation of skeletal muscle fiber development1.64e-021.00e+005.918115
GO:0006398histone mRNA 3'-end processing1.64e-021.00e+005.918115
GO:0045292mRNA cis splicing, via spliceosome1.64e-021.00e+005.918115
GO:0031442positive regulation of mRNA 3'-end processing1.64e-021.00e+005.918115
GO:0006449regulation of translational termination1.64e-021.00e+005.918115
GO:0036124histone H3-K9 trimethylation1.64e-021.00e+005.918115
GO:0016567protein ubiquitination1.70e-021.00e+002.01645299
GO:0000151ubiquitin ligase complex1.84e-021.00e+003.2622263
GO:0008762UDP-N-acetylmuramate dehydrogenase activity1.97e-021.00e+005.655116
GO:0010564regulation of cell cycle process1.97e-021.00e+005.655116
GO:0050847progesterone receptor signaling pathway1.97e-021.00e+005.655116
GO:0002181cytoplasmic translation1.97e-021.00e+005.655116
GO:0046974histone methyltransferase activity (H3-K9 specific)1.97e-021.00e+005.655116
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.97e-021.00e+005.655116
GO:0048024regulation of mRNA splicing, via spliceosome1.97e-021.00e+005.655116
GO:0006333chromatin assembly or disassembly1.97e-021.00e+005.655116
GO:0071204histone pre-mRNA 3'end processing complex1.97e-021.00e+005.655116
GO:0035497cAMP response element binding1.97e-021.00e+005.655116
GO:0042382paraspeckles1.97e-021.00e+005.655126
GO:0006310DNA recombination2.07e-021.00e+003.1732267
GO:0005739mitochondrion2.09e-021.00e+001.2098161046
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.25e-021.00e+003.1102470
GO:0046825regulation of protein export from nucleus2.29e-021.00e+005.432127
GO:0032790ribosome disassembly2.29e-021.00e+005.432117
GO:0002161aminoacyl-tRNA editing activity2.29e-021.00e+005.432117
GO:0042753positive regulation of circadian rhythm2.29e-021.00e+005.432117
GO:0004521endoribonuclease activity2.29e-021.00e+005.432117
GO:0010458exit from mitosis2.29e-021.00e+005.432117
GO:0006301postreplication repair2.29e-021.00e+005.432117
GO:0051444negative regulation of ubiquitin-protein transferase activity2.29e-021.00e+005.432117
GO:0006282regulation of DNA repair2.29e-021.00e+005.432117
GO:0035234ectopic germ cell programmed cell death2.29e-021.00e+005.432117
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.49e-021.00e+003.0302474
GO:0042754negative regulation of circadian rhythm2.62e-021.00e+005.240118
GO:0001955blood vessel maturation2.62e-021.00e+005.240118
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process2.62e-021.00e+002.9922276
GO:0000339RNA cap binding2.62e-021.00e+005.240118
GO:0033523histone H2B ubiquitination2.62e-021.00e+005.240118
GO:0071013catalytic step 2 spliceosome2.81e-021.00e+002.9362379
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.81e-021.00e+002.9362479
GO:0071354cellular response to interleukin-62.94e-021.00e+005.070119
GO:00084095'-3' exonuclease activity2.94e-021.00e+005.070119
GO:0048103somatic stem cell division2.94e-021.00e+005.070119
GO:0010388cullin deneddylation2.94e-021.00e+005.070159
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.94e-021.00e+005.070119
GO:0035253ciliary rootlet2.94e-021.00e+005.070119
GO:0033598mammary gland epithelial cell proliferation2.94e-021.00e+005.070119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.94e-021.00e+005.070119
GO:0006983ER overload response2.94e-021.00e+005.070119
GO:0000400four-way junction DNA binding2.94e-021.00e+005.070119
GO:0005832chaperonin-containing T-complex2.94e-021.00e+005.070119
GO:0003677DNA binding3.19e-021.00e+001.0109161351
GO:0008610lipid biosynthetic process3.26e-021.00e+004.9181110
GO:0002199zona pellucida receptor complex3.26e-021.00e+004.9181110
GO:0006450regulation of translational fidelity3.26e-021.00e+004.9181110
GO:0071949FAD binding3.26e-021.00e+004.9181110
GO:0008088axon cargo transport3.26e-021.00e+004.9181110
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay3.26e-021.00e+004.9181110
GO:0090399replicative senescence3.26e-021.00e+004.9181110
GO:0016032viral process3.26e-021.00e+001.485516540
GO:0000731DNA synthesis involved in DNA repair3.26e-021.00e+004.9181110
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway3.26e-021.00e+004.9181210
GO:0010944negative regulation of transcription by competitive promoter binding3.26e-021.00e+004.9181110
GO:0006351transcription, DNA-templated3.32e-021.00e+000.93110171585
GO:0006415translational termination3.36e-021.00e+002.7972287
GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling3.58e-021.00e+004.7801111
GO:0005845mRNA cap binding complex3.58e-021.00e+004.7801111
GO:0051010microtubule plus-end binding3.58e-021.00e+004.7801211
GO:0048387negative regulation of retinoic acid receptor signaling pathway3.58e-021.00e+004.7801111
GO:0071850mitotic cell cycle arrest3.58e-021.00e+004.7801111
GO:0045662negative regulation of myoblast differentiation3.58e-021.00e+004.7801111
GO:0010390histone monoubiquitination3.58e-021.00e+004.7801111
GO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening3.58e-021.00e+004.7801111
GO:0033235positive regulation of protein sumoylation3.58e-021.00e+004.7801111
GO:0035413positive regulation of catenin import into nucleus3.58e-021.00e+004.7801111
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process3.58e-021.00e+004.7801111
GO:0004535poly(A)-specific ribonuclease activity3.58e-021.00e+004.7801111
GO:2000036regulation of stem cell maintenance3.58e-021.00e+004.7801111
GO:0060391positive regulation of SMAD protein import into nucleus3.58e-021.00e+004.7801111
GO:0003700sequence-specific DNA binding transcription factor activity3.63e-021.00e+001.278610748
GO:0016363nuclear matrix3.72e-021.00e+002.7162592
GO:0034453microtubule anchoring3.90e-021.00e+004.6551112
GO:0061136regulation of proteasomal protein catabolic process3.90e-021.00e+004.6551112
GO:0008334histone mRNA metabolic process3.90e-021.00e+004.6551112
GO:0043517positive regulation of DNA damage response, signal transduction by p53 class mediator3.90e-021.00e+004.6551112
GO:0001953negative regulation of cell-matrix adhesion3.90e-021.00e+004.6551112
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process3.90e-021.00e+004.6551112
GO:0004861cyclin-dependent protein serine/threonine kinase inhibitor activity3.90e-021.00e+004.6551112
GO:0006364rRNA processing4.02e-021.00e+002.6552296
GO:0007067mitotic nuclear division4.09e-021.00e+001.97334231
GO:0007140male meiosis4.22e-021.00e+004.5391113
GO:0042974retinoic acid receptor binding4.22e-021.00e+004.5391113
GO:0060766negative regulation of androgen receptor signaling pathway4.22e-021.00e+004.5391113
GO:0060444branching involved in mammary gland duct morphogenesis4.22e-021.00e+004.5391113
GO:0035198miRNA binding4.22e-021.00e+004.5391113
GO:0003713transcription coactivator activity4.46e-021.00e+001.92437239
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.46e-021.00e+001.359510589
GO:0071480cellular response to gamma radiation4.54e-021.00e+004.4321114
GO:0007020microtubule nucleation4.54e-021.00e+004.4321114
GO:0005095GTPase inhibitor activity4.54e-021.00e+004.4321114
GO:0030889negative regulation of B cell proliferation4.54e-021.00e+004.4321114
GO:0045807positive regulation of endocytosis4.54e-021.00e+004.4321114
GO:0005730nucleolus4.74e-021.00e+000.84410281684
GO:0008134transcription factor binding4.78e-021.00e+001.88236246
GO:0050908detection of light stimulus involved in visual perception4.85e-021.00e+004.3331115
GO:0017091AU-rich element binding4.85e-021.00e+004.3331215
GO:0001824blastocyst development4.85e-021.00e+004.3331115
GO:0030014CCR4-NOT complex4.85e-021.00e+004.3331115
GO:0007026negative regulation of microtubule depolymerization5.17e-021.00e+004.2401216
GO:0016746transferase activity, transferring acyl groups5.17e-021.00e+004.2401216
GO:0051276chromosome organization5.17e-021.00e+004.2401216
GO:0005634nucleus5.23e-021.00e+000.46222554828
GO:0030308negative regulation of cell growth5.39e-021.00e+002.41922113
GO:0001829trophectodermal cell differentiation5.48e-021.00e+004.1521217
GO:0001731formation of translation preinitiation complex5.48e-021.00e+004.1521117
GO:0016409palmitoyltransferase activity5.48e-021.00e+004.1521117
GO:0048593camera-type eye morphogenesis5.48e-021.00e+004.1521117
GO:0006281DNA repair5.68e-021.00e+001.78034264
GO:0000166nucleotide binding6.10e-021.00e+001.73736272
GO:0017075syntaxin-1 binding6.11e-021.00e+003.9921119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process6.11e-021.00e+003.9921119
GO:0071158positive regulation of cell cycle arrest6.11e-021.00e+003.9921119
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity6.11e-021.00e+003.9921219
GO:0001578microtubule bundle formation6.42e-021.00e+003.9181120
GO:0090398cellular senescence6.42e-021.00e+003.9181120
GO:0097194execution phase of apoptosis6.42e-021.00e+003.9181120
GO:0005680anaphase-promoting complex6.42e-021.00e+003.9181120
GO:0018345protein palmitoylation6.42e-021.00e+003.9181120
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription6.42e-021.00e+003.9181120
GO:0006260DNA replication6.43e-021.00e+002.27424125
GO:0007050cell cycle arrest6.52e-021.00e+002.26223126
GO:0045862positive regulation of proteolysis6.73e-021.00e+003.8471221
GO:0032757positive regulation of interleukin-8 production6.73e-021.00e+003.8471121
GO:0042326negative regulation of phosphorylation6.73e-021.00e+003.8471121
GO:0016575histone deacetylation6.73e-021.00e+003.8471121
GO:0008637apoptotic mitochondrial changes6.73e-021.00e+003.8471121
GO:0006355regulation of transcription, DNA-templated7.03e-021.00e+000.9387131104
GO:0051924regulation of calcium ion transport7.04e-021.00e+003.7801122
GO:0005720nuclear heterochromatin7.04e-021.00e+003.7801122
GO:0006378mRNA polyadenylation7.04e-021.00e+003.7801222
GO:0036464cytoplasmic ribonucleoprotein granule7.04e-021.00e+003.7801122
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription7.04e-021.00e+003.7801222
GO:0071346cellular response to interferon-gamma7.34e-021.00e+003.7161223
GO:0034660ncRNA metabolic process7.34e-021.00e+003.7161123
GO:0005640nuclear outer membrane7.34e-021.00e+003.7161123
GO:0019706protein-cysteine S-palmitoyltransferase activity7.34e-021.00e+003.7161123
GO:0045879negative regulation of smoothened signaling pathway7.34e-021.00e+003.7161123
GO:0000086G2/M transition of mitotic cell cycle7.54e-021.00e+002.14223137
GO:0008135translation factor activity, nucleic acid binding7.65e-021.00e+003.6551224
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress7.65e-021.00e+003.6551124
GO:0007163establishment or maintenance of cell polarity7.65e-021.00e+003.6551124
GO:0045893positive regulation of transcription, DNA-templated7.71e-021.00e+001.31246487
GO:0042802identical protein binding7.89e-021.00e+001.30046491
GO:0016055Wnt signaling pathway7.93e-021.00e+002.10023141
GO:0030864cortical actin cytoskeleton7.96e-021.00e+003.5961125
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening7.96e-021.00e+003.5961125
GO:0031519PcG protein complex7.96e-021.00e+003.5961125
GO:0051059NF-kappaB binding7.96e-021.00e+003.5961225
GO:0044267cellular protein metabolic process8.08e-021.00e+001.28847495
GO:0035329hippo signaling8.26e-021.00e+003.5391126
GO:0070979protein K11-linked ubiquitination8.26e-021.00e+003.5391126
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolytic8.26e-021.00e+003.5391126
GO:0031424keratinization8.57e-021.00e+003.4851127
GO:0006913nucleocytoplasmic transport8.57e-021.00e+003.4851127
GO:0000188inactivation of MAPK activity8.57e-021.00e+003.4851127
GO:0030331estrogen receptor binding8.57e-021.00e+003.4851227
GO:0000387spliceosomal snRNP assembly8.57e-021.00e+003.4851127
GO:0007339binding of sperm to zona pellucida8.57e-021.00e+003.4851127
GO:0005737cytoplasm8.69e-021.00e+000.45218433976
GO:0000082G1/S transition of mitotic cell cycle8.81e-021.00e+002.01124150
GO:2001235positive regulation of apoptotic signaling pathway8.87e-021.00e+003.4321128
GO:0000976transcription regulatory region sequence-specific DNA binding8.87e-021.00e+003.4321128
GO:0043022ribosome binding8.87e-021.00e+003.4321228
GO:0033017sarcoplasmic reticulum membrane8.87e-021.00e+003.4321128
GO:0019894kinesin binding8.87e-021.00e+003.4321128
GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay9.17e-021.00e+003.3821129
GO:0019005SCF ubiquitin ligase complex9.17e-021.00e+003.3821129
GO:0016485protein processing9.17e-021.00e+003.3821129
GO:0003887DNA-directed DNA polymerase activity9.17e-021.00e+003.3821129
GO:0071897DNA biosynthetic process9.17e-021.00e+003.3821129
GO:0005525GTP binding9.45e-021.00e+001.46735328
GO:00063707-methylguanosine mRNA capping9.47e-021.00e+003.3331230
GO:0031647regulation of protein stability9.47e-021.00e+003.3331230
GO:0010494cytoplasmic stress granule9.47e-021.00e+003.3331230
GO:0010827regulation of glucose transport9.77e-021.00e+003.2851331
GO:0016604nuclear body9.77e-021.00e+003.2851131
GO:0007094mitotic spindle assembly checkpoint9.77e-021.00e+003.2851331
GO:0070534protein K63-linked ubiquitination9.77e-021.00e+003.2851131
GO:0005782peroxisomal matrix9.77e-021.00e+003.2851131
GO:0043005neuron projection9.93e-021.00e+001.90924161
GO:0042594response to starvation1.01e-011.00e+003.2401332
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic1.01e-011.00e+003.2401132
GO:0034644cellular response to UV1.01e-011.00e+003.2401132
GO:1903507negative regulation of nucleic acid-templated transcription1.01e-011.00e+003.2401132
GO:0007162negative regulation of cell adhesion1.04e-011.00e+003.1951133
GO:0001104RNA polymerase II transcription cofactor activity1.04e-011.00e+003.1951333
GO:0008180COP9 signalosome1.07e-011.00e+003.1521634
GO:0005876spindle microtubule1.07e-011.00e+003.1521134
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand1.10e-011.00e+003.1101135
GO:0009267cellular response to starvation1.13e-011.00e+003.0701136
GO:0006446regulation of translational initiation1.13e-011.00e+003.0701236
GO:0007077mitotic nuclear envelope disassembly1.16e-011.00e+003.0301337
GO:0006821chloride transport1.16e-011.00e+003.0301137
GO:0051084'de novo' posttranslational protein folding1.16e-011.00e+003.0301137
GO:0007049cell cycle1.16e-011.00e+001.77224177
GO:0005667transcription factor complex1.17e-011.00e+001.76423178
GO:0031625ubiquitin protein ligase binding1.19e-011.00e+001.74822180
GO:0043565sequence-specific DNA binding1.20e-011.00e+001.31333365
GO:0008285negative regulation of cell proliferation1.21e-011.00e+001.30534367
GO:0035019somatic stem cell maintenance1.24e-011.00e+002.9181240
GO:0034707chloride channel complex1.24e-011.00e+002.9181140
GO:0005881cytoplasmic microtubule1.27e-011.00e+002.8821241
GO:0005254chloride channel activity1.27e-011.00e+002.8821141
GO:0006418tRNA aminoacylation for protein translation1.30e-011.00e+002.8471342
GO:0008645hexose transport1.30e-011.00e+002.8471342
GO:0031514motile cilium1.30e-011.00e+002.8471142
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.36e-011.00e+002.7801144
GO:0005871kinesin complex1.36e-011.00e+002.7801144
GO:0050434positive regulation of viral transcription1.36e-011.00e+002.7801244
GO:0015030Cajal body1.39e-011.00e+002.7481145
GO:0001047core promoter binding1.42e-011.00e+002.7161246
GO:0044297cell body1.42e-011.00e+002.7161146
GO:0019827stem cell maintenance1.47e-011.00e+002.6551248
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage1.50e-011.00e+002.6251149
GO:0006986response to unfolded protein1.56e-011.00e+002.5671251
GO:0040008regulation of growth1.56e-011.00e+002.5671151
GO:0007254JNK cascade1.56e-011.00e+002.5671251
GO:0003684damaged DNA binding1.56e-011.00e+002.5671151
GO:0000775chromosome, centromeric region1.59e-011.00e+002.5391352
GO:0004197cysteine-type endopeptidase activity1.59e-011.00e+002.5391152
GO:0034976response to endoplasmic reticulum stress1.59e-011.00e+002.5391152
GO:0045454cell redox homeostasis1.59e-011.00e+002.5391152
GO:0009611response to wounding1.61e-011.00e+002.5121153
GO:0007623circadian rhythm1.64e-011.00e+002.4851254
GO:0000226microtubule cytoskeleton organization1.67e-011.00e+002.4581255
GO:0002039p53 binding1.67e-011.00e+002.4581355
GO:0000724double-strand break repair via homologous recombination1.72e-011.00e+002.4071157
GO:0015758glucose transport1.78e-011.00e+002.3571359
GO:0005643nuclear pore1.78e-011.00e+002.3571359
GO:0008013beta-catenin binding1.81e-011.00e+002.3331460
GO:0003777microtubule motor activity1.81e-011.00e+002.3331160
GO:0006412translation1.82e-011.00e+001.36325235
GO:0006987activation of signaling protein activity involved in unfolded protein response1.86e-011.00e+002.2851262
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.86e-011.00e+002.2851162
GO:0019903protein phosphatase binding1.89e-011.00e+002.2621163
GO:0000776kinetochore1.89e-011.00e+002.2621463
GO:0006417regulation of translation1.89e-011.00e+002.2621163
GO:0032088negative regulation of NF-kappaB transcription factor activity1.91e-011.00e+002.2401264
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.94e-011.00e+002.2171365
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.94e-011.00e+002.2171365
GO:0006469negative regulation of protein kinase activity1.94e-011.00e+002.2171265
GO:0071260cellular response to mechanical stimulus1.97e-011.00e+002.1951166
GO:0006368transcription elongation from RNA polymerase II promoter1.99e-011.00e+002.1731367
GO:0006338chromatin remodeling2.02e-011.00e+002.1521168
GO:0000777condensed chromosome kinetochore2.02e-011.00e+002.1521168
GO:0003697single-stranded DNA binding2.05e-011.00e+002.1311269
GO:1902476chloride transmembrane transport2.07e-011.00e+002.1101170
GO:0005874microtubule2.10e-011.00e+001.22823258
GO:0010468regulation of gene expression2.13e-011.00e+002.0701172
GO:0000785chromatin2.15e-011.00e+002.0501273
GO:0002020protease binding2.18e-011.00e+002.0301174
GO:0042826histone deacetylase binding2.18e-011.00e+002.0301274
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding2.21e-011.00e+002.0111175
GO:0007265Ras protein signal transduction2.21e-011.00e+002.0111275
GO:0006874cellular calcium ion homeostasis2.23e-011.00e+001.9921176
GO:0044325ion channel binding2.26e-011.00e+001.9731177
GO:0008584male gonad development2.26e-011.00e+001.9731177
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process2.26e-011.00e+001.9731277
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity2.26e-011.00e+001.9731277
GO:0006357regulation of transcription from RNA polymerase II promoter2.31e-011.00e+001.13624275
GO:0030968endoplasmic reticulum unfolded protein response2.36e-011.00e+001.9001281
GO:0051301cell division2.36e-011.00e+001.9001281
GO:0009952anterior/posterior pattern specification2.44e-011.00e+001.8471284
GO:0019899enzyme binding2.47e-011.00e+001.07023288
GO:0009653anatomical structure morphogenesis2.51e-011.00e+001.7971187
GO:0090090negative regulation of canonical Wnt signaling pathway2.54e-011.00e+001.7801488
GO:0006464cellular protein modification process2.56e-011.00e+001.7641189
GO:0005777peroxisome2.59e-011.00e+001.7481190
GO:0050821protein stabilization2.61e-011.00e+001.7321391
GO:0016337single organismal cell-cell adhesion2.63e-011.00e+001.7161192
GO:0008152metabolic process2.64e-011.00e+001.00122302
GO:0005770late endosome2.68e-011.00e+001.6851194
GO:0051082unfolded protein binding2.71e-011.00e+001.6701395
GO:0008270zinc ion binding2.77e-011.00e+000.5025111067
GO:0030018Z disc2.78e-011.00e+001.6251298
GO:0071456cellular response to hypoxia2.78e-011.00e+001.6251298
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.80e-011.00e+000.576413811
GO:0006470protein dephosphorylation2.80e-011.00e+001.6101199
GO:0051726regulation of cell cycle2.88e-011.00e+001.56714102
GO:0030154cell differentiation2.92e-011.00e+000.89522325
GO:0006915apoptotic process2.93e-011.00e+000.66738571
GO:0008283cell proliferation3.00e-011.00e+000.86923331
GO:0005938cell cortex3.04e-011.00e+001.47111109
GO:0005815microtubule organizing center3.06e-011.00e+001.45811110
GO:0005819spindle3.16e-011.00e+001.40712114
GO:0097190apoptotic signaling pathway3.20e-011.00e+001.38211116
GO:0005635nuclear envelope3.20e-011.00e+001.38213116
GO:0007568aging3.36e-011.00e+001.29712123
GO:0030335positive regulation of cell migration3.51e-011.00e+001.21712130
GO:0046983protein dimerization activity3.53e-011.00e+001.20611131
GO:0006413translational initiation3.53e-011.00e+001.20614131
GO:0044255cellular lipid metabolic process3.72e-011.00e+001.11011140
GO:0007165signal transduction3.86e-011.00e+000.34848950
GO:0010628positive regulation of gene expression3.91e-011.00e+001.02012149
GO:0006457protein folding3.91e-011.00e+001.02011149
GO:0016323basolateral plasma membrane3.91e-011.00e+001.02011149
GO:0042981regulation of apoptotic process3.95e-011.00e+001.00113151
GO:0006508proteolysis3.95e-011.00e+000.56022410
GO:0034220ion transmembrane transport4.27e-011.00e+000.85611167
GO:0007601visual perception4.29e-011.00e+000.84711168
GO:0006397mRNA processing4.30e-011.00e+000.83916169
GO:0007420brain development4.36e-011.00e+000.81311172
GO:0016607nuclear speck4.42e-011.00e+000.78816175
GO:0019904protein domain specific binding4.53e-011.00e+000.74012181
GO:0006367transcription initiation from RNA polymerase II promoter4.58e-011.00e+000.71615184
GO:0032403protein complex binding4.60e-011.00e+000.70812185
GO:0003924GTPase activity4.92e-011.00e+000.57412203
GO:0001701in utero embryonic development5.04e-011.00e+000.52512210
GO:0055085transmembrane transport5.11e-011.00e+000.23425514
GO:0006184GTP catabolic process5.20e-011.00e+000.45812220
GO:0005622intracellular5.30e-011.00e+000.41912226
GO:0019221cytokine-mediated signaling pathway5.36e-011.00e+000.39413230
GO:0007399nervous system development5.59e-011.00e+000.30313245
GO:0048011neurotrophin TRK receptor signaling pathway5.98e-011.00e+000.14712273
GO:0005975carbohydrate metabolic process6.00e-011.00e+000.14213274
GO:0043065positive regulation of apoptotic process6.00e-011.00e+000.14213274
GO:0003779actin binding6.01e-011.00e+000.13611275
GO:0007283spermatogenesis6.02e-011.00e+000.13111276
GO:0006954inflammatory response6.20e-011.00e+000.06511289
GO:0005743mitochondrial inner membrane6.33e-011.00e+000.01113300
GO:0043234protein complex6.33e-011.00e+000.01114300
GO:0005856cytoskeleton6.47e-011.00e+00-0.04112311
GO:0019901protein kinase binding6.57e-011.00e+00-0.08214320
GO:0005575cellular_component6.60e-011.00e+00-0.09111322
GO:0007411axon guidance6.65e-011.00e+00-0.11412327
GO:0005524ATP binding6.66e-011.00e+00-0.1634131354
GO:0043231intracellular membrane-bounded organelle6.71e-011.00e+00-0.13511332
GO:0003682chromatin binding6.73e-011.00e+00-0.14417334
GO:0005813centrosome6.79e-011.00e+00-0.16614339
GO:0007275multicellular organismal development6.84e-011.00e+00-0.18711344
GO:0046872metal ion binding7.26e-011.00e+00-0.277461465
GO:0046982protein heterodimerization activity7.38e-011.00e+00-0.40113399
GO:0009986cell surface7.58e-011.00e+00-0.48214422
GO:0055114oxidation-reduction process8.02e-011.00e+00-0.67012481
GO:0048471perinuclear region of cytoplasm8.28e-011.00e+00-0.79111523
GO:0003674molecular_function8.29e-011.00e+00-0.79411524
GO:0005783endoplasmic reticulum8.73e-011.00e+00-1.01312610
GO:0042803protein homodimerization activity8.76e-011.00e+00-1.03016617
GO:0005794Golgi apparatus8.89e-011.00e+00-1.10511650
GO:0044281small molecule metabolic process9.35e-011.00e+00-1.0992121295
GO:0005887integral component of plasma membrane9.62e-011.00e+00-1.66911961
GO:0005615extracellular space9.68e-011.00e+00-1.741141010
GO:0016021integral component of membrane9.92e-011.00e+00-1.453372483
GO:0070062extracellular vesicular exosome9.93e-011.00e+00-1.4723152516
GO:0005886plasma membrane9.97e-011.00e+00-1.6443142834