reg-snw-9618

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.828	9.19e-07	2.89e-03	5.50e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-9618 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	25	0.807	0.973	67	-	-	-
DDX41	51428	3	0.623	0.836	19	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
POLR2F	5435	14	0.891	0.956	5	-	Yes	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-
[ TRAF4 ]	9618	1	0.051	0.828	51	TF	Yes	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
EFTUD2	9343	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CAD	790	DDX41	51428	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CAD	790	TRAF4	9618	pd	<	reg.ITFP.txt: no annot

Related GO terms (170)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000398	mRNA splicing, via spliceosome	3.37e-06	3.29e-02	5.083	4	8	128
GO:0000812	Swr1 complex	1.58e-05	1.54e-01	8.276	2	2	7
GO:0071013	catalytic step 2 spliceosome	1.90e-05	1.85e-01	5.738	3	5	61
GO:0031011	Ino80 complex	2.11e-05	2.06e-01	8.083	2	2	8
GO:0016363	nuclear matrix	3.26e-05	3.18e-01	5.479	3	7	73
GO:0043968	histone H2A acetylation	3.39e-05	3.31e-01	7.762	2	2	10
GO:0035267	NuA4 histone acetyltransferase complex	4.96e-05	4.84e-01	7.499	2	3	12
GO:0003678	DNA helicase activity	1.15e-04	1.00e+00	6.914	2	3	18
GO:0071339	MLL1 complex	1.15e-04	1.00e+00	6.914	2	2	18
GO:0043967	histone H4 acetylation	1.73e-04	1.00e+00	6.624	2	2	22
GO:0016020	membrane	2.12e-04	1.00e+00	2.431	6	38	1207
GO:0008380	RNA splicing	3.69e-04	1.00e+00	4.302	3	7	165
GO:0040008	regulation of growth	4.95e-04	1.00e+00	5.874	2	2	37
GO:0032508	DNA duplex unwinding	5.22e-04	1.00e+00	5.836	2	5	38
GO:0005654	nucleoplasm	5.32e-04	1.00e+00	2.631	5	55	876
GO:0006281	DNA repair	6.78e-04	1.00e+00	4.003	3	19	203
GO:0032481	positive regulation of type I interferon production	8.33e-04	1.00e+00	5.499	2	5	48
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	8.68e-04	1.00e+00	5.469	2	3	49
GO:0006310	DNA recombination	9.04e-04	1.00e+00	5.440	2	6	50
GO:0004151	dihydroorotase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070335	aspartate binding	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	9.22e-04	1.00e+00	10.083	1	1	1
GO:0005681	spliceosomal complex	1.09e-03	1.00e+00	5.302	2	2	55
GO:0006325	chromatin organization	1.77e-03	1.00e+00	4.954	2	3	70
GO:0030323	respiratory tube development	1.84e-03	1.00e+00	9.083	1	1	2
GO:0030529	ribonucleoprotein complex	2.41e-03	1.00e+00	4.726	2	4	82
GO:0005730	nucleolus	2.44e-03	1.00e+00	2.156	5	41	1217
GO:0071733	transcriptional activation by promoter-enhancer looping	2.76e-03	1.00e+00	8.499	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006543	glutamine catabolic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0042802	identical protein binding	3.37e-03	1.00e+00	3.201	3	7	354
GO:0016887	ATPase activity	3.57e-03	1.00e+00	4.440	2	6	100
GO:0051414	response to cortisol	3.68e-03	1.00e+00	8.083	1	1	4
GO:0000212	meiotic spindle organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0071169	establishment of protein localization to chromatin	3.68e-03	1.00e+00	8.083	1	1	4
GO:0006228	UTP biosynthetic process	3.68e-03	1.00e+00	8.083	1	1	4
GO:0014075	response to amine	4.60e-03	1.00e+00	7.762	1	1	5
GO:0005827	polar microtubule	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0003924	GTPase activity	5.01e-03	1.00e+00	4.189	2	3	119
GO:0001055	RNA polymerase II activity	5.52e-03	1.00e+00	7.499	1	2	6
GO:0046134	pyrimidine nucleoside biosynthetic process	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031000	response to caffeine	5.52e-03	1.00e+00	7.499	1	1	6
GO:0006184	GTP catabolic process	5.96e-03	1.00e+00	4.061	2	3	130
GO:0005524	ATP binding	5.99e-03	1.00e+00	2.283	4	23	892
GO:0090073	positive regulation of protein homodimerization activity	6.44e-03	1.00e+00	7.276	1	1	7
GO:0031122	cytoplasmic microtubule organization	7.35e-03	1.00e+00	7.083	1	2	8
GO:0005634	nucleus	8.11e-03	1.00e+00	1.226	7	67	3246
GO:0031996	thioesterase binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0032479	regulation of type I interferon production	8.27e-03	1.00e+00	6.914	1	2	9
GO:0008266	poly(U) RNA binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	9.18e-03	1.00e+00	6.762	1	2	10
GO:0006541	glutamine metabolic process	9.18e-03	1.00e+00	6.762	1	1	10
GO:0035458	cellular response to interferon-beta	9.18e-03	1.00e+00	6.762	1	2	10
GO:0001054	RNA polymerase I activity	9.18e-03	1.00e+00	6.762	1	2	10
GO:0007020	microtubule nucleation	1.01e-02	1.00e+00	6.624	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	2	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0010467	gene expression	1.07e-02	1.00e+00	2.605	3	31	535
GO:0071392	cellular response to estradiol stimulus	1.19e-02	1.00e+00	6.383	1	1	13
GO:0005666	DNA-directed RNA polymerase III complex	1.19e-02	1.00e+00	6.383	1	2	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.19e-02	1.00e+00	6.383	1	2	13
GO:0001056	RNA polymerase III activity	1.19e-02	1.00e+00	6.383	1	2	13
GO:0035066	positive regulation of histone acetylation	1.19e-02	1.00e+00	6.383	1	1	13
GO:0006386	termination of RNA polymerase III transcription	1.28e-02	1.00e+00	6.276	1	2	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.28e-02	1.00e+00	6.276	1	2	14
GO:0050699	WW domain binding	1.28e-02	1.00e+00	6.276	1	1	14
GO:0005525	GTP binding	1.33e-02	1.00e+00	3.461	2	5	197
GO:0005829	cytosol	1.34e-02	1.00e+00	1.602	5	58	1787
GO:0007250	activation of NF-kappaB-inducing kinase activity	1.47e-02	1.00e+00	6.083	1	1	16
GO:0005719	nuclear euchromatin	1.47e-02	1.00e+00	6.083	1	1	16
GO:0043234	protein complex	1.50e-02	1.00e+00	3.369	2	8	210
GO:0006206	pyrimidine nucleobase metabolic process	1.56e-02	1.00e+00	5.996	1	2	17
GO:0071364	cellular response to epidermal growth factor stimulus	1.65e-02	1.00e+00	5.914	1	1	18
GO:0033574	response to testosterone	1.65e-02	1.00e+00	5.914	1	1	18
GO:0000794	condensed nuclear chromosome	1.65e-02	1.00e+00	5.914	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.83e-02	1.00e+00	5.762	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.83e-02	1.00e+00	5.762	1	2	20
GO:0017144	drug metabolic process	1.92e-02	1.00e+00	5.691	1	1	21
GO:0006370	7-methylguanosine mRNA capping	2.19e-02	1.00e+00	5.499	1	2	24
GO:0005164	tumor necrosis factor receptor binding	2.19e-02	1.00e+00	5.499	1	1	24
GO:0004003	ATP-dependent DNA helicase activity	2.28e-02	1.00e+00	5.440	1	2	25
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0031492	nucleosomal DNA binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0007585	respiratory gaseous exchange	2.28e-02	1.00e+00	5.440	1	1	25
GO:0006360	transcription from RNA polymerase I promoter	2.46e-02	1.00e+00	5.329	1	2	27
GO:0008270	zinc ion binding	2.46e-02	1.00e+00	2.163	3	7	727
GO:0034644	cellular response to UV	2.55e-02	1.00e+00	5.276	1	2	28
GO:0018107	peptidyl-threonine phosphorylation	2.64e-02	1.00e+00	5.225	1	2	29
GO:0006383	transcription from RNA polymerase III promoter	2.64e-02	1.00e+00	5.225	1	2	29
GO:0043195	terminal bouton	2.82e-02	1.00e+00	5.129	1	1	31
GO:0031490	chromatin DNA binding	2.82e-02	1.00e+00	5.129	1	1	31
GO:0015030	Cajal body	2.91e-02	1.00e+00	5.083	1	2	32
GO:0007595	lactation	2.91e-02	1.00e+00	5.083	1	2	32
GO:0046330	positive regulation of JNK cascade	3.09e-02	1.00e+00	4.996	1	1	34
GO:0044822	poly(A) RNA binding	3.15e-02	1.00e+00	2.026	3	25	799
GO:0050434	positive regulation of viral transcription	3.18e-02	1.00e+00	4.954	1	2	35
GO:0000226	microtubule cytoskeleton organization	3.27e-02	1.00e+00	4.914	1	2	36
GO:0045860	positive regulation of protein kinase activity	3.36e-02	1.00e+00	4.874	1	1	37
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	76	4124
GO:0035690	cellular response to drug	3.45e-02	1.00e+00	4.836	1	2	38
GO:0006396	RNA processing	3.63e-02	1.00e+00	4.762	1	1	40
GO:0006283	transcription-coupled nucleotide-excision repair	3.63e-02	1.00e+00	4.762	1	6	40
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3.63e-02	1.00e+00	4.762	1	2	40
GO:0042995	cell projection	3.72e-02	1.00e+00	4.726	1	2	41
GO:0003684	damaged DNA binding	3.72e-02	1.00e+00	4.726	1	9	41
GO:0004386	helicase activity	3.81e-02	1.00e+00	4.691	1	2	42
GO:0031100	organ regeneration	3.98e-02	1.00e+00	4.624	1	2	44
GO:0006334	nucleosome assembly	4.61e-02	1.00e+00	4.411	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	4.61e-02	1.00e+00	4.411	1	5	51
GO:0006368	transcription elongation from RNA polymerase II promoter	4.69e-02	1.00e+00	4.383	1	3	52
GO:0006289	nucleotide-excision repair	4.78e-02	1.00e+00	4.356	1	9	53
GO:0003677	DNA binding	4.89e-02	1.00e+00	1.781	3	18	947
GO:0070062	extracellular vesicular exosome	4.92e-02	1.00e+00	1.403	4	43	1641
GO:0006338	chromatin remodeling	4.96e-02	1.00e+00	4.302	1	2	55
GO:0006915	apoptotic process	5.23e-02	1.00e+00	2.400	2	21	411
GO:0007565	female pregnancy	5.75e-02	1.00e+00	4.083	1	2	64
GO:0005923	tight junction	5.75e-02	1.00e+00	4.083	1	2	64
GO:0005200	structural constituent of cytoskeleton	6.10e-02	1.00e+00	3.996	1	2	68
GO:0045087	innate immune response	6.20e-02	1.00e+00	2.263	2	7	452
GO:0051082	unfolded protein binding	6.27e-02	1.00e+00	3.954	1	4	70
GO:0001889	liver development	6.36e-02	1.00e+00	3.934	1	1	71
GO:0005737	cytoplasm	6.58e-02	1.00e+00	1.043	5	50	2633
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	2	74
GO:0005815	microtubule organizing center	6.88e-02	1.00e+00	3.817	1	1	77
GO:0051607	defense response to virus	8.17e-02	1.00e+00	3.560	1	1	92
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	5	97
GO:0006457	protein folding	8.60e-02	1.00e+00	3.484	1	4	97
GO:0007507	heart development	9.36e-02	1.00e+00	3.356	1	1	106
GO:0046777	protein autophosphorylation	9.36e-02	1.00e+00	3.356	1	2	106
GO:0000790	nuclear chromatin	9.61e-02	1.00e+00	3.315	1	3	109
GO:0006397	mRNA processing	9.70e-02	1.00e+00	3.302	1	2	110
GO:0042981	regulation of apoptotic process	9.87e-02	1.00e+00	3.276	1	18	112
GO:0016607	nuclear speck	1.07e-01	1.00e+00	3.153	1	3	122
GO:0004672	protein kinase activity	1.10e-01	1.00e+00	3.118	1	2	125
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.15e-01	1.00e+00	1.753	2	8	644
GO:0031625	ubiquitin protein ligase binding	1.20e-01	1.00e+00	2.975	1	5	138
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	2	142
GO:0005622	intracellular	1.26e-01	1.00e+00	2.904	1	1	145
GO:0006367	transcription initiation from RNA polymerase II promoter	1.39e-01	1.00e+00	2.753	1	4	161
GO:0007067	mitotic nuclear division	1.42e-01	1.00e+00	2.717	1	8	165
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0043025	neuronal cell body	1.47e-01	1.00e+00	2.666	1	3	171
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	6	176
GO:0004842	ubiquitin-protein transferase activity	1.53e-01	1.00e+00	2.600	1	2	179
GO:0016567	protein ubiquitination	1.61e-01	1.00e+00	2.529	1	3	188
GO:0005856	cytoskeleton	1.62e-01	1.00e+00	2.514	1	2	190
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.72e-01	1.00e+00	2.418	1	1	203
GO:0019899	enzyme binding	1.78e-01	1.00e+00	2.369	1	4	210
GO:0007275	multicellular organismal development	1.81e-01	1.00e+00	2.342	1	4	214
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	8	217
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	7	218
GO:0006200	ATP catabolic process	1.85e-01	1.00e+00	2.309	1	8	219
GO:0019901	protein kinase binding	1.95e-01	1.00e+00	2.225	1	11	232
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	11	247
GO:0000278	mitotic cell cycle	2.55e-01	1.00e+00	1.789	1	35	314
GO:0006351	transcription, DNA-templated	2.61e-01	1.00e+00	1.012	2	9	1076
GO:0006366	transcription from RNA polymerase II promoter	2.74e-01	1.00e+00	1.670	1	6	341
GO:0048471	perinuclear region of cytoplasm	2.76e-01	1.00e+00	1.657	1	5	344
GO:0005783	endoplasmic reticulum	3.01e-01	1.00e+00	1.510	1	3	381
GO:0005794	Golgi apparatus	3.24e-01	1.00e+00	1.387	1	5	415
GO:0016032	viral process	3.32e-01	1.00e+00	1.342	1	32	428
GO:0007165	signal transduction	4.45e-01	1.00e+00	0.812	1	5	618
GO:0044281	small molecule metabolic process	5.57e-01	1.00e+00	0.362	1	32	844
GO:0005886	plasma membrane	8.37e-01	1.00e+00	-0.717	1	11	1784

Wolf-ratios-Mammosphere-Adherent

reg-snw-9618

Statistics

Genes (9)

Interactions (11)

Related GO terms (170)