reg-snw-9401

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.823	1.14e-06	3.24e-03	6.09e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-9401 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	25	0.807	0.973	67	-	-	-
POLR2H	5437	3	0.775	0.862	14	-	Yes	-
ANP32B	10541	2	0.709	0.823	21	-	Yes	-
[ RECQL4 ]	9401	1	-0.010	0.823	115	TF	-	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPC	3183	RECQL4	9401	pd	<	reg.ITFP.txt: no annot
RECQL4	9401	ANP32B	10541	pd	>	reg.ITFP.txt: no annot
CAD	790	RECQL4	9401	pd	<	reg.ITFP.txt: no annot
POLR2H	5437	RECQL4	9401	pd	<	reg.ITFP.txt: no annot

Related GO terms (108)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004151	dihydroorotase activity	5.12e-04	1.00e+00	10.931	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	5.12e-04	1.00e+00	10.931	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	5.12e-04	1.00e+00	10.931	1	1	1
GO:0070335	aspartate binding	5.12e-04	1.00e+00	10.931	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	5.12e-04	1.00e+00	10.931	1	1	1
GO:0044205	'de novo' UMP biosynthetic process	1.54e-03	1.00e+00	9.347	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	1.54e-03	1.00e+00	9.347	1	1	3
GO:0006543	glutamine catabolic process	1.54e-03	1.00e+00	9.347	1	1	3
GO:0000398	mRNA splicing, via spliceosome	1.66e-03	1.00e+00	4.931	2	8	128
GO:0000405	bubble DNA binding	2.05e-03	1.00e+00	8.931	1	1	4
GO:0051414	response to cortisol	2.05e-03	1.00e+00	8.931	1	1	4
GO:0006228	UTP biosynthetic process	2.05e-03	1.00e+00	8.931	1	1	4
GO:0014075	response to amine	2.56e-03	1.00e+00	8.610	1	1	5
GO:0043140	ATP-dependent 3'-5' DNA helicase activity	2.56e-03	1.00e+00	8.610	1	1	5
GO:0008380	RNA splicing	2.74e-03	1.00e+00	4.565	2	7	165
GO:0046134	pyrimidine nucleoside biosynthetic process	3.07e-03	1.00e+00	8.347	1	1	6
GO:0001055	RNA polymerase II activity	3.07e-03	1.00e+00	8.347	1	2	6
GO:0031000	response to caffeine	3.07e-03	1.00e+00	8.347	1	1	6
GO:0036310	annealing helicase activity	3.58e-03	1.00e+00	8.124	1	1	7
GO:0070063	RNA polymerase binding	3.58e-03	1.00e+00	8.124	1	1	7
GO:0005634	nucleus	4.05e-03	1.00e+00	1.589	5	67	3246
GO:0000733	DNA strand renaturation	4.09e-03	1.00e+00	7.931	1	2	8
GO:0006281	DNA repair	4.13e-03	1.00e+00	4.266	2	19	203
GO:0043234	protein complex	4.41e-03	1.00e+00	4.217	2	8	210
GO:0021591	ventricular system development	4.60e-03	1.00e+00	7.762	1	1	9
GO:0008266	poly(U) RNA binding	4.60e-03	1.00e+00	7.762	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	5.11e-03	1.00e+00	7.610	1	2	10
GO:0001054	RNA polymerase I activity	5.11e-03	1.00e+00	7.610	1	2	10
GO:0006541	glutamine metabolic process	5.11e-03	1.00e+00	7.610	1	1	10
GO:0045120	pronucleus	5.62e-03	1.00e+00	7.472	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	5.62e-03	1.00e+00	7.472	1	2	11
GO:0046827	positive regulation of protein export from nucleus	5.62e-03	1.00e+00	7.472	1	1	11
GO:0005665	DNA-directed RNA polymerase II, core complex	6.64e-03	1.00e+00	7.231	1	2	13
GO:0001056	RNA polymerase III activity	6.64e-03	1.00e+00	7.231	1	2	13
GO:0005666	DNA-directed RNA polymerase III complex	6.64e-03	1.00e+00	7.231	1	2	13
GO:0006385	transcription elongation from RNA polymerase III promoter	7.15e-03	1.00e+00	7.124	1	2	14
GO:0006386	termination of RNA polymerase III transcription	7.15e-03	1.00e+00	7.124	1	2	14
GO:0001944	vasculature development	8.68e-03	1.00e+00	6.844	1	1	17
GO:0006206	pyrimidine nucleobase metabolic process	8.68e-03	1.00e+00	6.844	1	2	17
GO:0033574	response to testosterone	9.18e-03	1.00e+00	6.762	1	1	18
GO:0071364	cellular response to epidermal growth factor stimulus	9.18e-03	1.00e+00	6.762	1	1	18
GO:0045596	negative regulation of cell differentiation	1.02e-02	1.00e+00	6.610	1	1	20
GO:0043044	ATP-dependent chromatin remodeling	1.02e-02	1.00e+00	6.610	1	2	20
GO:0006362	transcription elongation from RNA polymerase I promoter	1.02e-02	1.00e+00	6.610	1	1	20
GO:0006363	termination of RNA polymerase I transcription	1.07e-02	1.00e+00	6.539	1	1	21
GO:0017144	drug metabolic process	1.07e-02	1.00e+00	6.539	1	1	21
GO:0006361	transcription initiation from RNA polymerase I promoter	1.17e-02	1.00e+00	6.408	1	1	23
GO:0042802	identical protein binding	1.22e-02	1.00e+00	3.464	2	7	354
GO:0006370	7-methylguanosine mRNA capping	1.22e-02	1.00e+00	6.347	1	2	24
GO:0048839	inner ear development	1.22e-02	1.00e+00	6.347	1	2	24
GO:0031492	nucleosomal DNA binding	1.27e-02	1.00e+00	6.288	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.27e-02	1.00e+00	6.288	1	2	25
GO:0006360	transcription from RNA polymerase I promoter	1.38e-02	1.00e+00	6.177	1	2	27
GO:0018107	peptidyl-threonine phosphorylation	1.48e-02	1.00e+00	6.073	1	2	29
GO:0006383	transcription from RNA polymerase III promoter	1.48e-02	1.00e+00	6.073	1	2	29
GO:0016020	membrane	1.55e-02	1.00e+00	2.279	3	38	1207
GO:0043195	terminal bouton	1.58e-02	1.00e+00	5.977	1	1	31
GO:0007595	lactation	1.63e-02	1.00e+00	5.931	1	2	32
GO:0050434	positive regulation of viral transcription	1.78e-02	1.00e+00	5.802	1	2	35
GO:0035690	cellular response to drug	1.93e-02	1.00e+00	5.684	1	2	38
GO:0032508	DNA duplex unwinding	1.93e-02	1.00e+00	5.684	1	5	38
GO:0006283	transcription-coupled nucleotide-excision repair	2.03e-02	1.00e+00	5.610	1	6	40
GO:0042995	cell projection	2.08e-02	1.00e+00	5.574	1	2	41
GO:0031100	organ regeneration	2.23e-02	1.00e+00	5.472	1	2	44
GO:0060021	palate development	2.38e-02	1.00e+00	5.377	1	1	47
GO:0032481	positive regulation of type I interferon production	2.43e-02	1.00e+00	5.347	1	5	48
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.48e-02	1.00e+00	5.317	1	3	49
GO:0006310	DNA recombination	2.53e-02	1.00e+00	5.288	1	6	50
GO:0006334	nucleosome assembly	2.58e-02	1.00e+00	5.259	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	2.58e-02	1.00e+00	5.259	1	5	51
GO:0006368	transcription elongation from RNA polymerase II promoter	2.63e-02	1.00e+00	5.231	1	3	52
GO:0010467	gene expression	2.68e-02	1.00e+00	2.868	2	31	535
GO:0006289	nucleotide-excision repair	2.69e-02	1.00e+00	5.204	1	9	53
GO:0042393	histone binding	2.74e-02	1.00e+00	5.177	1	3	54
GO:0005681	spliceosomal complex	2.79e-02	1.00e+00	5.150	1	2	55
GO:0071013	catalytic step 2 spliceosome	3.09e-02	1.00e+00	5.001	1	5	61
GO:0007565	female pregnancy	3.23e-02	1.00e+00	4.931	1	2	64
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	3.38e-02	1.00e+00	4.865	1	2	67
GO:0001889	liver development	3.58e-02	1.00e+00	4.782	1	1	71
GO:0070062	extracellular vesicular exosome	3.63e-02	1.00e+00	1.836	3	43	1641
GO:0016363	nuclear matrix	3.68e-02	1.00e+00	4.742	1	7	73
GO:0001649	osteoblast differentiation	3.73e-02	1.00e+00	4.722	1	2	74
GO:0005829	cytosol	4.57e-02	1.00e+00	1.713	3	58	1787
GO:0006260	DNA replication	4.72e-02	1.00e+00	4.377	1	11	94
GO:0008270	zinc ion binding	4.76e-02	1.00e+00	2.426	2	7	727
GO:0007507	heart development	5.31e-02	1.00e+00	4.204	1	1	106
GO:0046777	protein autophosphorylation	5.31e-02	1.00e+00	4.204	1	2	106
GO:0000790	nuclear chromatin	5.46e-02	1.00e+00	4.163	1	3	109
GO:0004672	protein kinase activity	6.24e-02	1.00e+00	3.966	1	2	125
GO:0005654	nucleoplasm	6.69e-02	1.00e+00	2.157	2	55	876
GO:0005524	ATP binding	6.92e-02	1.00e+00	2.131	2	23	892
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	7.06e-02	1.00e+00	3.782	1	2	142
GO:0006367	transcription initiation from RNA polymerase II promoter	7.98e-02	1.00e+00	3.601	1	4	161
GO:0043025	neuronal cell body	8.46e-02	1.00e+00	3.514	1	3	171
GO:0000166	nucleotide binding	8.69e-02	1.00e+00	3.472	1	6	176
GO:0019899	enzyme binding	1.03e-01	1.00e+00	3.217	1	4	210
GO:0007275	multicellular organismal development	1.05e-01	1.00e+00	3.190	1	4	214
GO:0006200	ATP catabolic process	1.07e-01	1.00e+00	3.157	1	8	219
GO:0005730	nucleolus	1.20e-01	1.00e+00	1.682	2	41	1217
GO:0003723	RNA binding	1.20e-01	1.00e+00	2.983	1	11	247
GO:0006366	transcription from RNA polymerase II promoter	1.63e-01	1.00e+00	2.518	1	6	341
GO:0016032	viral process	2.01e-01	1.00e+00	2.190	1	32	428
GO:0045087	innate immune response	2.11e-01	1.00e+00	2.111	1	7	452
GO:0044822	poly(A) RNA binding	3.47e-01	1.00e+00	1.289	1	25	799
GO:0044281	small molecule metabolic process	3.64e-01	1.00e+00	1.210	1	32	844
GO:0003677	DNA binding	4.00e-01	1.00e+00	1.044	1	18	947
GO:0005737	cytoplasm	4.09e-01	1.00e+00	0.569	2	50	2633
GO:0005515	protein binding	9.36e-01	1.00e+00	-1.078	1	76	4124

Wolf-ratios-Mammosphere-Adherent

reg-snw-9401

Statistics

Genes (5)

Interactions (4)

Related GO terms (108)