reg-snw-3978

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.805	2.20e-06	4.59e-03	8.32e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-3978 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ LIG1 ]	3978	1	0.164	0.805	117	TF	-	-
CAD	790	25	0.807	0.973	67	-	-	-
POLR2H	5437	3	0.775	0.862	14	-	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-
MCM5	4174	5	0.578	0.830	152	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	LIG1	3978	pd	<	reg.ITFP.txt: no annot
LIG1	3978	MCM5	4174	pd	<>	reg.ITFP.txt: no annot
CAD	790	LIG1	3978	pd	<	reg.ITFP.txt: no annot
LIG1	3978	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
LIG1	3978	POLR2H	5437	pd	>	reg.ITFP.txt: no annot
CAD	790	MCM5	4174	pd	<	reg.ITFP.txt: no annot

Related GO terms (150)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	3.19e-05	3.12e-01	3.216	5	55	876
GO:0003678	DNA helicase activity	4.79e-05	4.68e-01	7.499	2	3	18
GO:0006271	DNA strand elongation involved in DNA replication	1.27e-04	1.00e+00	6.810	2	8	29
GO:0006281	DNA repair	1.69e-04	1.00e+00	4.588	3	19	203
GO:0032508	DNA duplex unwinding	2.19e-04	1.00e+00	6.421	2	5	38
GO:0006283	transcription-coupled nucleotide-excision repair	2.43e-04	1.00e+00	6.347	2	6	40
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.65e-04	1.00e+00	6.054	2	3	49
GO:0006289	nucleotide-excision repair	4.28e-04	1.00e+00	5.941	2	9	53
GO:0004151	dihydroorotase activity	6.14e-04	1.00e+00	10.668	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	6.14e-04	1.00e+00	10.668	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	6.14e-04	1.00e+00	10.668	1	1	1
GO:0070335	aspartate binding	6.14e-04	1.00e+00	10.668	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	6.14e-04	1.00e+00	10.668	1	1	1
GO:0016363	nuclear matrix	8.11e-04	1.00e+00	5.479	2	7	73
GO:0042802	identical protein binding	8.71e-04	1.00e+00	3.786	3	7	354
GO:0005524	ATP binding	8.93e-04	1.00e+00	2.868	4	23	892
GO:0005634	nucleus	1.34e-03	1.00e+00	1.589	6	67	3246
GO:0003910	DNA ligase (ATP) activity	1.84e-03	1.00e+00	9.083	1	1	3
GO:0003909	DNA ligase activity	1.84e-03	1.00e+00	9.083	1	1	3
GO:0071733	transcriptional activation by promoter-enhancer looping	1.84e-03	1.00e+00	9.083	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	1.84e-03	1.00e+00	9.083	1	1	3
GO:0006543	glutamine catabolic process	1.84e-03	1.00e+00	9.083	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	1.84e-03	1.00e+00	9.083	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	1.84e-03	1.00e+00	9.083	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	1.84e-03	1.00e+00	9.083	1	1	3
GO:0051414	response to cortisol	2.46e-03	1.00e+00	8.668	1	1	4
GO:0071169	establishment of protein localization to chromatin	2.46e-03	1.00e+00	8.668	1	1	4
GO:0006228	UTP biosynthetic process	2.46e-03	1.00e+00	8.668	1	1	4
GO:0006273	lagging strand elongation	2.46e-03	1.00e+00	8.668	1	2	4
GO:0000398	mRNA splicing, via spliceosome	2.47e-03	1.00e+00	4.668	2	8	128
GO:0016020	membrane	2.83e-03	1.00e+00	2.431	4	38	1207
GO:0005730	nucleolus	2.92e-03	1.00e+00	2.419	4	41	1217
GO:0051103	DNA ligation involved in DNA repair	3.07e-03	1.00e+00	8.347	1	1	5
GO:0014075	response to amine	3.07e-03	1.00e+00	8.347	1	1	5
GO:0001055	RNA polymerase II activity	3.68e-03	1.00e+00	8.083	1	2	6
GO:0046134	pyrimidine nucleoside biosynthetic process	3.68e-03	1.00e+00	8.083	1	1	6
GO:0031000	response to caffeine	3.68e-03	1.00e+00	8.083	1	1	6
GO:0042555	MCM complex	3.68e-03	1.00e+00	8.083	1	1	6
GO:0008380	RNA splicing	4.07e-03	1.00e+00	4.302	2	7	165
GO:0000812	Swr1 complex	4.29e-03	1.00e+00	7.861	1	2	7
GO:0033151	V(D)J recombination	4.29e-03	1.00e+00	7.861	1	2	7
GO:0031011	Ino80 complex	4.91e-03	1.00e+00	7.668	1	2	8
GO:0008266	poly(U) RNA binding	5.52e-03	1.00e+00	7.499	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	6.13e-03	1.00e+00	7.347	1	2	10
GO:0006541	glutamine metabolic process	6.13e-03	1.00e+00	7.347	1	1	10
GO:0043968	histone H2A acetylation	6.13e-03	1.00e+00	7.347	1	2	10
GO:0001054	RNA polymerase I activity	6.13e-03	1.00e+00	7.347	1	2	10
GO:0043234	protein complex	6.52e-03	1.00e+00	3.954	2	8	210
GO:0070935	3'-UTR-mediated mRNA stabilization	6.74e-03	1.00e+00	7.209	1	2	11
GO:0045120	pronucleus	6.74e-03	1.00e+00	7.209	1	1	11
GO:0035267	NuA4 histone acetyltransferase complex	7.35e-03	1.00e+00	7.083	1	3	12
GO:0071392	cellular response to estradiol stimulus	7.96e-03	1.00e+00	6.968	1	1	13
GO:0005666	DNA-directed RNA polymerase III complex	7.96e-03	1.00e+00	6.968	1	2	13
GO:0005665	DNA-directed RNA polymerase II, core complex	7.96e-03	1.00e+00	6.968	1	2	13
GO:0001056	RNA polymerase III activity	7.96e-03	1.00e+00	6.968	1	2	13
GO:0035066	positive regulation of histone acetylation	7.96e-03	1.00e+00	6.968	1	1	13
GO:0006386	termination of RNA polymerase III transcription	8.57e-03	1.00e+00	6.861	1	2	14
GO:0006259	DNA metabolic process	8.57e-03	1.00e+00	6.861	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	8.57e-03	1.00e+00	6.861	1	2	14
GO:0005719	nuclear euchromatin	9.79e-03	1.00e+00	6.668	1	1	16
GO:0006206	pyrimidine nucleobase metabolic process	1.04e-02	1.00e+00	6.581	1	2	17
GO:0006270	DNA replication initiation	1.04e-02	1.00e+00	6.581	1	4	17
GO:0071364	cellular response to epidermal growth factor stimulus	1.10e-02	1.00e+00	6.499	1	1	18
GO:0006297	nucleotide-excision repair, DNA gap filling	1.10e-02	1.00e+00	6.499	1	5	18
GO:0071339	MLL1 complex	1.10e-02	1.00e+00	6.499	1	2	18
GO:0033574	response to testosterone	1.10e-02	1.00e+00	6.499	1	1	18
GO:0006303	double-strand break repair via nonhomologous end joining	1.10e-02	1.00e+00	6.499	1	4	18
GO:0043044	ATP-dependent chromatin remodeling	1.22e-02	1.00e+00	6.347	1	2	20
GO:0006362	transcription elongation from RNA polymerase I promoter	1.22e-02	1.00e+00	6.347	1	1	20
GO:0032201	telomere maintenance via semi-conservative replication	1.22e-02	1.00e+00	6.347	1	7	20
GO:0071897	DNA biosynthetic process	1.22e-02	1.00e+00	6.347	1	2	20
GO:0006363	termination of RNA polymerase I transcription	1.28e-02	1.00e+00	6.276	1	1	21
GO:0017144	drug metabolic process	1.28e-02	1.00e+00	6.276	1	1	21
GO:0043967	histone H4 acetylation	1.34e-02	1.00e+00	6.209	1	2	22
GO:0000722	telomere maintenance via recombination	1.34e-02	1.00e+00	6.209	1	7	22
GO:0006361	transcription initiation from RNA polymerase I promoter	1.41e-02	1.00e+00	6.145	1	1	23
GO:0000278	mitotic cell cycle	1.42e-02	1.00e+00	3.374	2	35	314
GO:0003677	DNA binding	1.45e-02	1.00e+00	2.366	3	18	947
GO:0006370	7-methylguanosine mRNA capping	1.47e-02	1.00e+00	6.083	1	2	24
GO:0004003	ATP-dependent DNA helicase activity	1.53e-02	1.00e+00	6.025	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.53e-02	1.00e+00	6.025	1	2	25
GO:0031492	nucleosomal DNA binding	1.53e-02	1.00e+00	6.025	1	2	25
GO:0006360	transcription from RNA polymerase I promoter	1.65e-02	1.00e+00	5.914	1	2	27
GO:0034644	cellular response to UV	1.71e-02	1.00e+00	5.861	1	2	28
GO:0018107	peptidyl-threonine phosphorylation	1.77e-02	1.00e+00	5.810	1	2	29
GO:0006383	transcription from RNA polymerase III promoter	1.77e-02	1.00e+00	5.810	1	2	29
GO:0043195	terminal bouton	1.89e-02	1.00e+00	5.714	1	1	31
GO:0031490	chromatin DNA binding	1.89e-02	1.00e+00	5.714	1	1	31
GO:0007595	lactation	1.95e-02	1.00e+00	5.668	1	2	32
GO:0006284	base-excision repair	1.95e-02	1.00e+00	5.668	1	8	32
GO:0050434	positive regulation of viral transcription	2.13e-02	1.00e+00	5.539	1	2	35
GO:0042542	response to hydrogen peroxide	2.19e-02	1.00e+00	5.499	1	1	36
GO:0040008	regulation of growth	2.25e-02	1.00e+00	5.459	1	2	37
GO:0035690	cellular response to drug	2.31e-02	1.00e+00	5.421	1	2	38
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2.43e-02	1.00e+00	5.347	1	2	40
GO:0042995	cell projection	2.49e-02	1.00e+00	5.311	1	2	41
GO:0003684	damaged DNA binding	2.49e-02	1.00e+00	5.311	1	9	41
GO:0000724	double-strand break repair via homologous recombination	2.55e-02	1.00e+00	5.276	1	5	42
GO:0031100	organ regeneration	2.67e-02	1.00e+00	5.209	1	2	44
GO:0000723	telomere maintenance	2.85e-02	1.00e+00	5.114	1	8	47
GO:0032481	positive regulation of type I interferon production	2.91e-02	1.00e+00	5.083	1	5	48
GO:0051301	cell division	2.97e-02	1.00e+00	5.054	1	3	49
GO:0006310	DNA recombination	3.03e-02	1.00e+00	5.025	1	6	50
GO:0055086	nucleobase-containing small molecule metabolic process	3.09e-02	1.00e+00	4.996	1	5	51
GO:0006368	transcription elongation from RNA polymerase II promoter	3.15e-02	1.00e+00	4.968	1	3	52
GO:0006302	double-strand break repair	3.15e-02	1.00e+00	4.968	1	8	52
GO:0006338	chromatin remodeling	3.33e-02	1.00e+00	4.887	1	2	55
GO:0005681	spliceosomal complex	3.33e-02	1.00e+00	4.887	1	2	55
GO:0005694	chromosome	3.33e-02	1.00e+00	4.887	1	1	55
GO:0071013	catalytic step 2 spliceosome	3.69e-02	1.00e+00	4.738	1	5	61
GO:0007565	female pregnancy	3.87e-02	1.00e+00	4.668	1	2	64
GO:0010467	gene expression	3.88e-02	1.00e+00	2.605	2	31	535
GO:0009653	anatomical structure morphogenesis	3.93e-02	1.00e+00	4.646	1	1	65
GO:0051082	unfolded protein binding	4.23e-02	1.00e+00	4.539	1	4	70
GO:0006325	chromatin organization	4.23e-02	1.00e+00	4.539	1	3	70
GO:0001889	liver development	4.29e-02	1.00e+00	4.519	1	1	71
GO:0001649	osteoblast differentiation	4.46e-02	1.00e+00	4.459	1	2	74
GO:0030529	ribonucleoprotein complex	4.94e-02	1.00e+00	4.311	1	4	82
GO:0006260	DNA replication	5.64e-02	1.00e+00	4.114	1	11	94
GO:0006457	protein folding	5.82e-02	1.00e+00	4.069	1	4	97
GO:0016887	ATPase activity	5.99e-02	1.00e+00	4.025	1	6	100
GO:0007507	heart development	6.34e-02	1.00e+00	3.941	1	1	106
GO:0046777	protein autophosphorylation	6.34e-02	1.00e+00	3.941	1	2	106
GO:0070062	extracellular vesicular exosome	6.36e-02	1.00e+00	1.573	3	43	1641
GO:0000790	nuclear chromatin	6.51e-02	1.00e+00	3.900	1	3	109
GO:0004672	protein kinase activity	7.44e-02	1.00e+00	3.703	1	2	125
GO:0000082	G1/S transition of mitotic cell cycle	7.44e-02	1.00e+00	3.703	1	24	125
GO:0005829	cytosol	7.91e-02	1.00e+00	1.450	3	58	1787
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.42e-02	1.00e+00	3.519	1	2	142
GO:0005622	intracellular	8.59e-02	1.00e+00	3.489	1	1	145
GO:0006367	transcription initiation from RNA polymerase II promoter	9.50e-02	1.00e+00	3.338	1	4	161
GO:0043025	neuronal cell body	1.01e-01	1.00e+00	3.251	1	3	171
GO:0000166	nucleotide binding	1.03e-01	1.00e+00	3.209	1	6	176
GO:0019899	enzyme binding	1.22e-01	1.00e+00	2.954	1	4	210
GO:0043231	intracellular membrane-bounded organelle	1.27e-01	1.00e+00	2.900	1	7	218
GO:0006200	ATP catabolic process	1.27e-01	1.00e+00	2.894	1	8	219
GO:0003723	RNA binding	1.43e-01	1.00e+00	2.720	1	11	247
GO:0006366	transcription from RNA polymerase II promoter	1.92e-01	1.00e+00	2.255	1	6	341
GO:0005794	Golgi apparatus	2.29e-01	1.00e+00	1.971	1	5	415
GO:0016032	viral process	2.36e-01	1.00e+00	1.927	1	32	428
GO:0045087	innate immune response	2.48e-01	1.00e+00	1.848	1	7	452
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.36e-01	1.00e+00	1.338	1	8	644
GO:0005739	mitochondrion	3.43e-01	1.00e+00	1.304	1	11	659
GO:0008270	zinc ion binding	3.71e-01	1.00e+00	1.163	1	7	727
GO:0044822	poly(A) RNA binding	4.01e-01	1.00e+00	1.026	1	25	799
GO:0044281	small molecule metabolic process	4.19e-01	1.00e+00	0.947	1	32	844
GO:0046872	metal ion binding	4.53e-01	1.00e+00	0.801	1	10	934
GO:0005515	protein binding	5.02e-01	1.00e+00	0.244	3	76	4124
GO:0006351	transcription, DNA-templated	5.04e-01	1.00e+00	0.597	1	9	1076
GO:0005737	cytoplasm	8.48e-01	1.00e+00	-0.694	1	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-3978

Statistics

Genes (6)

Interactions (8)

Related GO terms (150)