reg-snw-3159

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.866	2.12e-07	1.31e-03	2.72e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-3159 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CCNA2	890	10	0.550	0.973	246	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
POLR2F	5435	14	0.891	0.956	5	-	Yes	-
PSMD3	5709	9	0.986	0.938	55	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
VARS	7407	7	0.549	0.938	124	TF	Yes	-
[ HMGA1 ]	3159	1	0.432	0.866	69	TF	Yes	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CCNA2	890	HMGA1	3159	pd	<>	reg.ITFP.txt: no annot
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
POLR2F	5435	VARS	7407	pd	<	reg.ITFP.txt: no annot
CCNA2	890	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
HMGA1	3159	VARS	7407	pd	<>	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot

Related GO terms (159)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.40e-06	1.37e-02	3.116	7	55	876
GO:0010467	gene expression	5.08e-05	4.96e-01	3.342	5	31	535
GO:0000278	mitotic cell cycle	1.16e-04	1.00e+00	3.789	4	35	314
GO:0005829	cytosol	1.73e-04	1.00e+00	2.088	7	58	1787
GO:0016032	viral process	3.85e-04	1.00e+00	3.342	4	32	428
GO:0006521	regulation of cellular amino acid metabolic process	6.08e-04	1.00e+00	5.726	2	16	41
GO:0000502	proteasome complex	7.99e-04	1.00e+00	5.529	2	17	47
GO:0004832	valine-tRNA ligase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006438	valyl-tRNA aminoacylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.78e-04	1.00e+00	5.383	2	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.02e-03	1.00e+00	5.356	2	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.13e-03	1.00e+00	5.276	2	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.17e-03	1.00e+00	5.251	2	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.30e-03	1.00e+00	5.177	2	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.34e-03	1.00e+00	5.153	2	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.52e-03	1.00e+00	5.061	2	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.77e-03	1.00e+00	4.954	2	16	70
GO:0031936	negative regulation of chromatin silencing	1.84e-03	1.00e+00	9.083	1	1	2
GO:0090402	oncogene-induced cell senescence	1.84e-03	1.00e+00	9.083	1	1	2
GO:0005730	nucleolus	2.44e-03	1.00e+00	2.156	5	41	1217
GO:0035985	senescence-associated heterochromatin focus	2.76e-03	1.00e+00	8.499	1	1	3
GO:0035986	senescence-associated heterochromatin focus assembly	2.76e-03	1.00e+00	8.499	1	1	3
GO:0000209	protein polyubiquitination	3.03e-03	1.00e+00	4.560	2	16	92
GO:0000086	G2/M transition of mitotic cell cycle	3.36e-03	1.00e+00	4.484	2	5	97
GO:0000212	meiotic spindle organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:2000774	positive regulation of cellular senescence	3.68e-03	1.00e+00	8.083	1	1	4
GO:0001940	male pronucleus	3.68e-03	1.00e+00	8.083	1	1	4
GO:0051575	5'-deoxyribose-5-phosphate lyase activity	3.68e-03	1.00e+00	8.083	1	2	4
GO:0034641	cellular nitrogen compound metabolic process	3.92e-03	1.00e+00	4.369	2	18	105
GO:0042981	regulation of apoptotic process	4.45e-03	1.00e+00	4.276	2	18	112
GO:0005827	polar microtubule	4.60e-03	1.00e+00	7.762	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0001939	female pronucleus	4.60e-03	1.00e+00	7.762	1	1	5
GO:0001055	RNA polymerase II activity	5.52e-03	1.00e+00	7.499	1	2	6
GO:0003680	AT DNA binding	5.52e-03	1.00e+00	7.499	1	1	6
GO:0000082	G1/S transition of mitotic cell cycle	5.52e-03	1.00e+00	4.118	2	24	125
GO:0000398	mRNA splicing, via spliceosome	5.78e-03	1.00e+00	4.083	2	8	128
GO:0010389	regulation of G2/M transition of mitotic cell cycle	6.44e-03	1.00e+00	7.276	1	1	7
GO:0033762	response to glucagon	6.44e-03	1.00e+00	7.276	1	1	7
GO:0000812	Swr1 complex	6.44e-03	1.00e+00	7.276	1	2	7
GO:0006450	regulation of translational fidelity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0031122	cytoplasmic microtubule organization	7.35e-03	1.00e+00	7.083	1	2	8
GO:0075713	establishment of integrated proviral latency	7.35e-03	1.00e+00	7.083	1	2	8
GO:0031011	Ino80 complex	7.35e-03	1.00e+00	7.083	1	2	8
GO:0005634	nucleus	8.11e-03	1.00e+00	1.226	7	67	3246
GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	8.27e-03	1.00e+00	6.914	1	2	9
GO:0008266	poly(U) RNA binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	9.18e-03	1.00e+00	6.762	1	2	10
GO:0042974	retinoic acid receptor binding	9.18e-03	1.00e+00	6.762	1	1	10
GO:0006268	DNA unwinding involved in DNA replication	9.18e-03	1.00e+00	6.762	1	1	10
GO:0043968	histone H2A acetylation	9.18e-03	1.00e+00	6.762	1	2	10
GO:0005838	proteasome regulatory particle	9.18e-03	1.00e+00	6.762	1	4	10
GO:0001054	RNA polymerase I activity	9.18e-03	1.00e+00	6.762	1	2	10
GO:0008380	RNA splicing	9.45e-03	1.00e+00	3.717	2	7	165
GO:0007067	mitotic nuclear division	9.45e-03	1.00e+00	3.717	2	8	165
GO:0016071	mRNA metabolic process	1.00e-02	1.00e+00	3.674	2	21	170
GO:0007020	microtubule nucleation	1.01e-02	1.00e+00	6.624	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	2	11
GO:0030234	enzyme regulator activity	1.01e-02	1.00e+00	6.624	1	2	11
GO:0042975	peroxisome proliferator activated receptor binding	1.01e-02	1.00e+00	6.624	1	1	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0035267	NuA4 histone acetyltransferase complex	1.10e-02	1.00e+00	6.499	1	3	12
GO:0046965	retinoid X receptor binding	1.10e-02	1.00e+00	6.499	1	1	12
GO:0006337	nucleosome disassembly	1.19e-02	1.00e+00	6.383	1	2	13
GO:0005666	DNA-directed RNA polymerase III complex	1.19e-02	1.00e+00	6.383	1	2	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.19e-02	1.00e+00	6.383	1	2	13
GO:0007095	mitotic G2 DNA damage checkpoint	1.19e-02	1.00e+00	6.383	1	1	13
GO:0001056	RNA polymerase III activity	1.19e-02	1.00e+00	6.383	1	2	13
GO:0016070	RNA metabolic process	1.21e-02	1.00e+00	3.529	2	21	188
GO:0006386	termination of RNA polymerase III transcription	1.28e-02	1.00e+00	6.276	1	2	14
GO:0010243	response to organonitrogen compound	1.28e-02	1.00e+00	6.276	1	1	14
GO:0042176	regulation of protein catabolic process	1.28e-02	1.00e+00	6.276	1	2	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.28e-02	1.00e+00	6.276	1	2	14
GO:0022624	proteasome accessory complex	1.28e-02	1.00e+00	6.276	1	7	14
GO:0006281	DNA repair	1.41e-02	1.00e+00	3.418	2	19	203
GO:0005839	proteasome core complex	1.47e-02	1.00e+00	6.083	1	9	16
GO:0004298	threonine-type endopeptidase activity	1.56e-02	1.00e+00	5.996	1	9	17
GO:0003678	DNA helicase activity	1.65e-02	1.00e+00	5.914	1	3	18
GO:0071339	MLL1 complex	1.65e-02	1.00e+00	5.914	1	2	18
GO:0000794	condensed nuclear chromosome	1.65e-02	1.00e+00	5.914	1	3	18
GO:0016020	membrane	1.75e-02	1.00e+00	1.846	4	38	1207
GO:0043044	ATP-dependent chromatin remodeling	1.83e-02	1.00e+00	5.762	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.83e-02	1.00e+00	5.762	1	2	20
GO:0043967	histone H4 acetylation	2.01e-02	1.00e+00	5.624	1	2	22
GO:0006370	7-methylguanosine mRNA capping	2.19e-02	1.00e+00	5.499	1	2	24
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0031492	nucleosomal DNA binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0006360	transcription from RNA polymerase I promoter	2.46e-02	1.00e+00	5.329	1	2	27
GO:0006418	tRNA aminoacylation for protein translation	2.64e-02	1.00e+00	5.225	1	1	29
GO:0000737	DNA catabolic process, endonucleolytic	2.64e-02	1.00e+00	5.225	1	3	29
GO:0006383	transcription from RNA polymerase III promoter	2.64e-02	1.00e+00	5.225	1	2	29
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	2.73e-02	1.00e+00	5.177	1	2	30
GO:0006284	base-excision repair	2.91e-02	1.00e+00	5.083	1	8	32
GO:0014070	response to organic cyclic compound	3.09e-02	1.00e+00	4.996	1	1	34
GO:0048146	positive regulation of fibroblast proliferation	3.18e-02	1.00e+00	4.954	1	1	35
GO:0050434	positive regulation of viral transcription	3.18e-02	1.00e+00	4.954	1	2	35
GO:0000226	microtubule cytoskeleton organization	3.27e-02	1.00e+00	4.914	1	2	36
GO:0043066	negative regulation of apoptotic process	3.35e-02	1.00e+00	2.753	2	20	322
GO:0040008	regulation of growth	3.36e-02	1.00e+00	4.874	1	2	37
GO:0032508	DNA duplex unwinding	3.45e-02	1.00e+00	4.836	1	5	38
GO:0006283	transcription-coupled nucleotide-excision repair	3.63e-02	1.00e+00	4.762	1	6	40
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	3.72e-02	1.00e+00	4.726	1	2	41
GO:0031100	organ regeneration	3.98e-02	1.00e+00	4.624	1	2	44
GO:0032481	positive regulation of type I interferon production	4.34e-02	1.00e+00	4.499	1	5	48
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	4.43e-02	1.00e+00	4.469	1	3	49
GO:0045893	positive regulation of transcription, DNA-templated	4.47e-02	1.00e+00	2.525	2	10	377
GO:0006310	DNA recombination	4.52e-02	1.00e+00	4.440	1	6	50
GO:0006334	nucleosome assembly	4.61e-02	1.00e+00	4.411	1	4	51
GO:0006368	transcription elongation from RNA polymerase II promoter	4.69e-02	1.00e+00	4.383	1	3	52
GO:0006289	nucleotide-excision repair	4.78e-02	1.00e+00	4.356	1	9	53
GO:0070062	extracellular vesicular exosome	4.92e-02	1.00e+00	1.403	4	43	1641
GO:0005681	spliceosomal complex	4.96e-02	1.00e+00	4.302	1	2	55
GO:0032355	response to estradiol	5.13e-02	1.00e+00	4.251	1	1	57
GO:0006915	apoptotic process	5.23e-02	1.00e+00	2.400	2	21	411
GO:0007265	Ras protein signal transduction	5.31e-02	1.00e+00	4.201	1	3	59
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	5	61
GO:0005200	structural constituent of cytoskeleton	6.10e-02	1.00e+00	3.996	1	2	68
GO:0006325	chromatin organization	6.27e-02	1.00e+00	3.954	1	3	70
GO:0016363	nuclear matrix	6.53e-02	1.00e+00	3.894	1	7	73
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	2	74
GO:0005815	microtubule organizing center	6.88e-02	1.00e+00	3.817	1	1	77
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	4	82
GO:0006461	protein complex assembly	8.08e-02	1.00e+00	3.576	1	3	91
GO:0009615	response to virus	8.60e-02	1.00e+00	3.484	1	3	97
GO:0016887	ATPase activity	8.85e-02	1.00e+00	3.440	1	6	100
GO:0000790	nuclear chromatin	9.61e-02	1.00e+00	3.315	1	3	109
GO:0003924	GTPase activity	1.05e-01	1.00e+00	3.189	1	3	119
GO:0006184	GTP catabolic process	1.14e-01	1.00e+00	3.061	1	3	130
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	2	142
GO:0005515	protein binding	1.26e-01	1.00e+00	0.659	6	76	4124
GO:0005667	transcription factor complex	1.28e-01	1.00e+00	2.884	1	3	147
GO:0006367	transcription initiation from RNA polymerase II promoter	1.39e-01	1.00e+00	2.753	1	4	161
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	6	176
GO:0005525	GTP binding	1.68e-01	1.00e+00	2.461	1	5	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.72e-01	1.00e+00	2.418	1	1	203
GO:0008134	transcription factor binding	1.77e-01	1.00e+00	2.376	1	4	209
GO:0043234	protein complex	1.78e-01	1.00e+00	2.369	1	8	210
GO:0019899	enzyme binding	1.78e-01	1.00e+00	2.369	1	4	210
GO:0044281	small molecule metabolic process	1.79e-01	1.00e+00	1.362	2	32	844
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	8	217
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	7	218
GO:0019901	protein kinase binding	1.95e-01	1.00e+00	2.225	1	11	232
GO:0005524	ATP binding	1.96e-01	1.00e+00	1.283	2	23	892
GO:0005737	cytoplasm	2.04e-01	1.00e+00	0.721	4	50	2633
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	11	247
GO:0003677	DNA binding	2.15e-01	1.00e+00	1.196	2	18	947
GO:0008285	negative regulation of cell proliferation	2.28e-01	1.00e+00	1.970	1	4	277
GO:0005925	focal adhesion	2.32e-01	1.00e+00	1.944	1	4	282
GO:0045892	negative regulation of transcription, DNA-templated	2.57e-01	1.00e+00	1.775	1	7	317
GO:0006351	transcription, DNA-templated	2.61e-01	1.00e+00	1.012	2	9	1076
GO:0006366	transcription from RNA polymerase II promoter	2.74e-01	1.00e+00	1.670	1	6	341
GO:0042802	identical protein binding	2.83e-01	1.00e+00	1.616	1	7	354
GO:0005794	Golgi apparatus	3.24e-01	1.00e+00	1.387	1	5	415
GO:0045087	innate immune response	3.47e-01	1.00e+00	1.263	1	7	452
GO:0005739	mitochondrion	4.67e-01	1.00e+00	0.719	1	11	659
GO:0006355	regulation of transcription, DNA-templated	4.96e-01	1.00e+00	0.602	1	7	715
GO:0044822	poly(A) RNA binding	5.36e-01	1.00e+00	0.441	1	25	799

Wolf-ratios-Mammosphere-Adherent

reg-snw-3159

Statistics

Genes (9)

Interactions (11)

Related GO terms (159)