reg-snw-22929

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.803 2.32e-06 4.72e-03 8.53e-03
wolf-screen-ratio-mammosphere-adherent-reg-snw-22929 subnetwork

Genes (14)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree Transcription factor wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
CAD 790 250.8070.97367---
PSMB1 5689 50.6880.90128-Yes-
RUVBL1 8607 240.7200.973126TFYes-
POLR2F 5435 140.8910.9565-Yes-
PHB2 11331 80.8290.95611-Yes-
EFTUD2 9343 170.8830.95630-Yes-
RBM8A 9939 20.4500.89947TFYes-
HNRNPC 3183 401.8120.97362-Yes-
PSMB2 5690 230.8770.95652-Yes-
TUBG1 7283 390.9740.97336-Yes-
RUVBL2 10856 200.6930.956187TFYes-
RAN 5901 80.6320.89983-Yes-
FBL 2091 90.8390.95614-Yes-
[ SEPHS1 ] 22929 10.1520.80313---

Interactions (17)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
RAN 5901 RBM8A 9939 pd < reg.ITFP.txt: no annot
RUVBL2 10856 SEPHS1 22929 pd > reg.ITFP.txt: no annot
FBL 2091 RUVBL2 10856 pd < reg.ITFP.txt: no annot
RUVBL2 10856 PHB2 11331 pd > reg.ITFP.txt: no annot
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
RBM8A 9939 SEPHS1 22929 pd > reg.ITFP.txt: no annot

Related GO terms (217)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005654nucleoplasm4.79e-074.67e-032.841955876
GO:0016363nuclear matrix2.72e-062.66e-025.2564773
GO:0010467gene expression3.49e-063.41e-023.190731535
GO:0000398mRNA splicing, via spliceosome2.55e-052.49e-014.44648128
GO:0000812Swr1 complex3.99e-053.90e-017.639227
GO:0031011Ino80 complex5.32e-055.19e-017.446228
GO:0008380RNA splicing6.89e-056.73e-014.08047165
GO:0005634nucleus7.88e-057.69e-011.36712673246
GO:0016020membrane8.03e-057.84e-012.2098381207
GO:0071013catalytic step 2 spliceosome8.04e-057.85e-015.1003561
GO:0005730nucleolus8.53e-058.33e-012.1978411217
GO:0043968histone H2A acetylation8.53e-058.33e-017.1242210
GO:0070062extracellular vesicular exosome9.32e-059.10e-011.9369431641
GO:0035267NuA4 histone acetyltransferase complex1.25e-041.00e+006.8612312
GO:0005525GTP binding1.37e-041.00e+003.82445197
GO:0005839proteasome core complex2.26e-041.00e+006.4462916
GO:0004298threonine-type endopeptidase activity2.56e-041.00e+006.3592917
GO:0003678DNA helicase activity2.88e-041.00e+006.2762318
GO:0071339MLL1 complex2.88e-041.00e+006.2762218
GO:0043967histone H4 acetylation4.34e-041.00e+005.9872222
GO:0003924GTPase activity5.82e-041.00e+004.13633119
GO:0006184GTP catabolic process7.54e-041.00e+004.00933130
GO:0015030Cajal body9.24e-041.00e+005.4462232
GO:0005515protein binding1.09e-031.00e+001.02112764124
GO:0040008regulation of growth1.24e-031.00e+005.2372237
GO:0005829cytosol1.30e-031.00e+001.6438581787
GO:0032508DNA duplex unwinding1.30e-031.00e+005.1982538
GO:1990259histone-glutamine methyltransferase activity1.43e-031.00e+009.446111
GO:1990258histone glutamine methylation1.43e-031.00e+009.446111
GO:0004756selenide, water dikinase activity1.43e-031.00e+009.446111
GO:0004151dihydroorotase activity1.43e-031.00e+009.446111
GO:0004070aspartate carbamoyltransferase activity1.43e-031.00e+009.446111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity1.43e-031.00e+009.446111
GO:0070335aspartate binding1.43e-031.00e+009.446111
GO:0016074snoRNA metabolic process1.43e-031.00e+009.446111
GO:0070409carbamoyl phosphate biosynthetic process1.43e-031.00e+009.446111
GO:0006521regulation of cellular amino acid metabolic process1.52e-031.00e+005.08821641
GO:0016071mRNA metabolic process1.64e-031.00e+003.622321170
GO:0000502proteasome complex1.99e-031.00e+004.89121747
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding2.16e-031.00e+004.8312349
GO:0016070RNA metabolic process2.19e-031.00e+003.476321188
GO:0006310DNA recombination2.25e-031.00e+004.8022650
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.43e-031.00e+004.74621752
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.52e-031.00e+004.71821753
GO:0016032viral process2.57e-031.00e+002.705432428
GO:0005681spliceosomal complex2.71e-031.00e+004.6652255
GO:0006281DNA repair2.72e-031.00e+003.366319203
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.81e-031.00e+004.63921756
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.91e-031.00e+004.61321657
GO:0043234protein complex3.00e-031.00e+003.31738210
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.22e-031.00e+004.53921760
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.33e-031.00e+004.51521661
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.77e-031.00e+004.42421765
GO:0044822poly(A) RNA binding3.88e-031.00e+002.126525799
GO:0071733transcriptional activation by promoter-enhancer looping4.30e-031.00e+007.861113
GO:0043141ATP-dependent 5'-3' DNA helicase activity4.30e-031.00e+007.861113
GO:0000056ribosomal small subunit export from nucleus4.30e-031.00e+007.861113
GO:0006543glutamine catabolic process4.30e-031.00e+007.861113
GO:0001652granular component4.30e-031.00e+007.861113
GO:0044205'de novo' UMP biosynthetic process4.30e-031.00e+007.861113
GO:0071899negative regulation of estrogen receptor binding4.30e-031.00e+007.861113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process4.30e-031.00e+007.861113
GO:0031428box C/D snoRNP complex4.30e-031.00e+007.861113
GO:0006325chromatin organization4.36e-031.00e+004.3172370
GO:0002474antigen processing and presentation of peptide antigen via MHC class I4.36e-031.00e+004.31721670
GO:0003723RNA binding4.73e-031.00e+003.083311247
GO:0001649osteoblast differentiation4.86e-031.00e+004.2372274
GO:0051414response to cortisol5.72e-031.00e+007.446114
GO:0000212meiotic spindle organization5.72e-031.00e+007.446114
GO:0071169establishment of protein localization to chromatin5.72e-031.00e+007.446114
GO:0006228UTP biosynthetic process5.72e-031.00e+007.446114
GO:0000055ribosomal large subunit export from nucleus5.72e-031.00e+007.446114
GO:0060762regulation of branching involved in mammary gland duct morphogenesis5.72e-031.00e+007.446114
GO:0030529ribonucleoprotein complex5.94e-031.00e+004.0882482
GO:0033600negative regulation of mammary gland epithelial cell proliferation7.15e-031.00e+007.124115
GO:0014075response to amine7.15e-031.00e+007.124115
GO:0060744mammary gland branching involved in thelarche7.15e-031.00e+007.124115
GO:0005827polar microtubule7.15e-031.00e+007.124115
GO:0000930gamma-tubulin complex7.15e-031.00e+007.124115
GO:0000209protein polyubiquitination7.42e-031.00e+003.92221692
GO:0001055RNA polymerase II activity8.57e-031.00e+006.861126
GO:0046134pyrimidine nucleoside biosynthetic process8.57e-031.00e+006.861116
GO:0031000response to caffeine8.57e-031.00e+006.861116
GO:0016887ATPase activity8.72e-031.00e+003.80226100
GO:0000278mitotic cell cycle9.21e-031.00e+002.736335314
GO:0034641cellular nitrogen compound metabolic process9.58e-031.00e+003.732218105
GO:0075733intracellular transport of virus1.00e-021.00e+006.639117
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway1.00e-021.00e+006.639117
GO:0042981regulation of apoptotic process1.08e-021.00e+003.639218112
GO:0031122cytoplasmic microtubule organization1.14e-021.00e+006.446128
GO:0042802identical protein binding1.28e-021.00e+002.56337354
GO:0016607nuclear speck1.28e-021.00e+003.51523122
GO:0008266poly(U) RNA binding1.28e-021.00e+006.276119
GO:0000082G1/S transition of mitotic cell cycle1.34e-021.00e+003.480224125
GO:0005736DNA-directed RNA polymerase I complex1.43e-021.00e+006.1241210
GO:0006541glutamine metabolic process1.43e-021.00e+006.1241110
GO:0001054RNA polymerase I activity1.43e-021.00e+006.1241210
GO:0007020microtubule nucleation1.57e-021.00e+005.9871111
GO:00709353'-UTR-mediated mRNA stabilization1.57e-021.00e+005.9871211
GO:0045120pronucleus1.57e-021.00e+005.9871111
GO:0071392cellular response to estradiol stimulus1.85e-021.00e+005.7461113
GO:0005666DNA-directed RNA polymerase III complex1.85e-021.00e+005.7461213
GO:0005665DNA-directed RNA polymerase II, core complex1.85e-021.00e+005.7461213
GO:0001056RNA polymerase III activity1.85e-021.00e+005.7461213
GO:0035066positive regulation of histone acetylation1.85e-021.00e+005.7461113
GO:0060749mammary gland alveolus development1.85e-021.00e+005.7461113
GO:0006386termination of RNA polymerase III transcription1.99e-021.00e+005.6391214
GO:0010243response to organonitrogen compound1.99e-021.00e+005.6391114
GO:0006259DNA metabolic process1.99e-021.00e+005.6391314
GO:0006385transcription elongation from RNA polymerase III promoter1.99e-021.00e+005.6391214
GO:0035145exon-exon junction complex2.13e-021.00e+005.5391115
GO:0007067mitotic nuclear division2.26e-021.00e+003.08028165
GO:0005719nuclear euchromatin2.27e-021.00e+005.4461116
GO:0006206pyrimidine nucleobase metabolic process2.41e-021.00e+005.3591217
GO:0007052mitotic spindle organization2.41e-021.00e+005.3591217
GO:0006611protein export from nucleus2.55e-021.00e+005.2761218
GO:0071364cellular response to epidermal growth factor stimulus2.55e-021.00e+005.2761118
GO:0033574response to testosterone2.55e-021.00e+005.2761118
GO:0000166nucleotide binding2.55e-021.00e+002.98726176
GO:0000794condensed nuclear chromosome2.55e-021.00e+005.2761318
GO:0044281small molecule metabolic process2.75e-021.00e+001.725432844
GO:0043044ATP-dependent chromatin remodeling2.83e-021.00e+005.1241220
GO:0034080CENP-A containing nucleosome assembly2.83e-021.00e+005.1241220
GO:0000381regulation of alternative mRNA splicing, via spliceosome2.97e-021.00e+005.0541121
GO:0017144drug metabolic process2.97e-021.00e+005.0541121
GO:0030331estrogen receptor binding3.11e-021.00e+004.9871122
GO:0007286spermatid development3.25e-021.00e+004.9221123
GO:0005524ATP binding3.29e-021.00e+001.645423892
GO:00063707-methylguanosine mRNA capping3.39e-021.00e+004.8611224
GO:0004003ATP-dependent DNA helicase activity3.53e-021.00e+004.8021225
GO:0008033tRNA processing3.53e-021.00e+004.8021125
GO:0003730mRNA 3'-UTR binding3.53e-021.00e+004.8021225
GO:0031492nucleosomal DNA binding3.53e-021.00e+004.8021225
GO:0006360transcription from RNA polymerase I promoter3.80e-021.00e+004.6911227
GO:0034644cellular response to UV3.94e-021.00e+004.6391228
GO:0018107peptidyl-threonine phosphorylation4.08e-021.00e+004.5881229
GO:0006383transcription from RNA polymerase III promoter4.08e-021.00e+004.5881229
GO:0050681androgen receptor binding4.22e-021.00e+004.5391230
GO:0043195terminal bouton4.36e-021.00e+004.4921131
GO:0031490chromatin DNA binding4.36e-021.00e+004.4921131
GO:0007595lactation4.49e-021.00e+004.4461232
GO:0019003GDP binding4.77e-021.00e+004.3591134
GO:0014070response to organic cyclic compound4.77e-021.00e+004.3591134
GO:0032092positive regulation of protein binding4.77e-021.00e+004.3591134
GO:0050434positive regulation of viral transcription4.91e-021.00e+004.3171235
GO:0030521androgen receptor signaling pathway4.91e-021.00e+004.3171235
GO:0031124mRNA 3'-end processing4.91e-021.00e+004.3171235
GO:0000226microtubule cytoskeleton organization5.04e-021.00e+004.2761236
GO:0035690cellular response to drug5.32e-021.00e+004.1981238
GO:0006369termination of RNA polymerase II transcription5.32e-021.00e+004.1981238
GO:0006417regulation of translation5.45e-021.00e+004.1611139
GO:0005737cytoplasm5.58e-021.00e+000.8917502633
GO:0006283transcription-coupled nucleotide-excision repair5.59e-021.00e+004.1241640
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding5.59e-021.00e+004.1241240
GO:0042995cell projection5.72e-021.00e+004.0881241
GO:0003684damaged DNA binding5.72e-021.00e+004.0881941
GO:0031100organ regeneration6.13e-021.00e+003.9871244
GO:0006406mRNA export from nucleus6.13e-021.00e+003.9871144
GO:0032481positive regulation of type I interferon production6.67e-021.00e+003.8611548
GO:0006334nucleosome assembly7.07e-021.00e+003.7741451
GO:0005643nuclear pore7.07e-021.00e+003.7741251
GO:0055086nucleobase-containing small molecule metabolic process7.07e-021.00e+003.7741551
GO:0006368transcription elongation from RNA polymerase II promoter7.21e-021.00e+003.7461352
GO:0006289nucleotide-excision repair7.34e-021.00e+003.7181953
GO:0043066negative regulation of apoptotic process7.60e-021.00e+002.115220322
GO:0006338chromatin remodeling7.61e-021.00e+003.6651255
GO:0003729mRNA binding7.87e-021.00e+003.6131257
GO:0000785chromatin8.14e-021.00e+003.5631559
GO:0016310phosphorylation8.27e-021.00e+003.5391160
GO:0006366transcription from RNA polymerase II promoter8.39e-021.00e+002.03226341
GO:0006464cellular protein modification process8.40e-021.00e+003.5151161
GO:0007565female pregnancy8.80e-021.00e+003.4461264
GO:0042470melanosome8.80e-021.00e+003.4461264
GO:0006364rRNA processing9.19e-021.00e+003.3801467
GO:0005200structural constituent of cytoskeleton9.33e-021.00e+003.3591268
GO:0051082unfolded protein binding9.59e-021.00e+003.3171470
GO:0001889liver development9.72e-021.00e+003.2961171
GO:0005815microtubule organizing center1.05e-011.00e+003.1791177
GO:0019058viral life cycle1.06e-011.00e+003.1611378
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.14e-011.00e+003.0541384
GO:0006915apoptotic process1.15e-011.00e+001.763221411
GO:0000086G2/M transition of mitotic cell cycle1.31e-011.00e+002.8461597
GO:0006457protein folding1.31e-011.00e+002.8461497
GO:0007507heart development1.42e-011.00e+002.71811106
GO:0046777protein autophosphorylation1.42e-011.00e+002.71812106
GO:0000790nuclear chromatin1.46e-011.00e+002.67813109
GO:0006397mRNA processing1.47e-011.00e+002.66512110
GO:0004672protein kinase activity1.65e-011.00e+002.48012125
GO:0031965nuclear membrane1.71e-011.00e+002.42413130
GO:0019904protein domain specific binding1.71e-011.00e+002.42412130
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.86e-011.00e+002.29612142
GO:0005622intracellular1.89e-011.00e+002.26611145
GO:0006351transcription, DNA-templated1.94e-011.00e+000.960391076
GO:0006367transcription initiation from RNA polymerase II promoter2.08e-011.00e+002.11514161
GO:0007283spermatogenesis2.16e-011.00e+002.05412168
GO:0043025neuronal cell body2.19e-011.00e+002.02813171
GO:0007264small GTPase mediated signal transduction2.23e-011.00e+002.00311174
GO:0003713transcription coactivator activity2.34e-011.00e+001.92215184
GO:0005743mitochondrial inner membrane2.48e-011.00e+001.82413197
GO:0006357regulation of transcription from RNA polymerase II promoter2.55e-011.00e+001.78111203
GO:0019899enzyme binding2.63e-011.00e+001.73214210
GO:0005813centrosome2.70e-011.00e+001.68418217
GO:0043231intracellular membrane-bounded organelle2.71e-011.00e+001.67817218
GO:0006200ATP catabolic process2.72e-011.00e+001.67118219
GO:0003682chromatin binding3.07e-011.00e+001.46916252
GO:0046982protein heterodimerization activity3.20e-011.00e+001.39615265
GO:0045892negative regulation of transcription, DNA-templated3.70e-011.00e+001.13817317
GO:0045893positive regulation of transcription, DNA-templated4.24e-011.00e+000.888110377
GO:0005794Golgi apparatus4.56e-011.00e+000.74915415
GO:0042803protein homodimerization activity4.66e-011.00e+000.70515428
GO:0045087innate immune response4.85e-011.00e+000.62617452
GO:0007165signal transduction6.00e-011.00e+000.17515618
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.15e-011.00e+000.11518644
GO:0005739mitochondrion6.24e-011.00e+000.082111659
GO:0008270zinc ion binding6.62e-011.00e+00-0.06017727
GO:0003677DNA binding7.60e-011.00e+00-0.441118947
GO:0005886plasma membrane9.41e-011.00e+00-1.3551111784