reg-snw-2023

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.836	6.94e-07	2.49e-03	4.81e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-2023 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
CAD	790	25	0.807	0.973	67	-	-	-
DDX41	51428	3	0.623	0.836	19	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
[ ENO1 ]	2023	1	-0.078	0.836	59	TF	-	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CAD	790	DDX41	51428	pd	<	reg.ITFP.txt: no annot
ENO1	2023	DDX41	51428	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot

Related GO terms (129)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016020	membrane	1.54e-04	1.00e+00	2.753	5	38	1207
GO:0071013	catalytic step 2 spliceosome	5.67e-04	1.00e+00	5.738	2	5	61
GO:0004151	dihydroorotase activity	6.14e-04	1.00e+00	10.668	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	6.14e-04	1.00e+00	10.668	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	6.14e-04	1.00e+00	10.668	1	1	1
GO:0070335	aspartate binding	6.14e-04	1.00e+00	10.668	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	6.14e-04	1.00e+00	10.668	1	1	1
GO:0016363	nuclear matrix	8.11e-04	1.00e+00	5.479	2	7	73
GO:0005829	cytosol	1.04e-03	1.00e+00	2.187	5	58	1787
GO:0006543	glutamine catabolic process	1.84e-03	1.00e+00	9.083	1	1	3
GO:0000015	phosphopyruvate hydratase complex	1.84e-03	1.00e+00	9.083	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	1.84e-03	1.00e+00	9.083	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	1.84e-03	1.00e+00	9.083	1	1	3
GO:0004634	phosphopyruvate hydratase activity	1.84e-03	1.00e+00	9.083	1	1	3
GO:0051414	response to cortisol	2.46e-03	1.00e+00	8.668	1	1	4
GO:0000212	meiotic spindle organization	2.46e-03	1.00e+00	8.668	1	1	4
GO:0006228	UTP biosynthetic process	2.46e-03	1.00e+00	8.668	1	1	4
GO:0000398	mRNA splicing, via spliceosome	2.47e-03	1.00e+00	4.668	2	8	128
GO:0014075	response to amine	3.07e-03	1.00e+00	8.347	1	1	5
GO:0005827	polar microtubule	3.07e-03	1.00e+00	8.347	1	1	5
GO:0000930	gamma-tubulin complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0046134	pyrimidine nucleoside biosynthetic process	3.68e-03	1.00e+00	8.083	1	1	6
GO:0031000	response to caffeine	3.68e-03	1.00e+00	8.083	1	1	6
GO:0000812	Swr1 complex	4.29e-03	1.00e+00	7.861	1	2	7
GO:0031122	cytoplasmic microtubule organization	4.91e-03	1.00e+00	7.668	1	2	8
GO:0031011	Ino80 complex	4.91e-03	1.00e+00	7.668	1	2	8
GO:0032479	regulation of type I interferon production	5.52e-03	1.00e+00	7.499	1	2	9
GO:0008266	poly(U) RNA binding	5.52e-03	1.00e+00	7.499	1	1	9
GO:0006541	glutamine metabolic process	6.13e-03	1.00e+00	7.347	1	1	10
GO:0035458	cellular response to interferon-beta	6.13e-03	1.00e+00	7.347	1	2	10
GO:0043968	histone H2A acetylation	6.13e-03	1.00e+00	7.347	1	2	10
GO:0043234	protein complex	6.52e-03	1.00e+00	3.954	2	8	210
GO:0007020	microtubule nucleation	6.74e-03	1.00e+00	7.209	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	6.74e-03	1.00e+00	7.209	1	2	11
GO:0045120	pronucleus	6.74e-03	1.00e+00	7.209	1	1	11
GO:0035267	NuA4 histone acetyltransferase complex	7.35e-03	1.00e+00	7.083	1	3	12
GO:0031430	M band	8.57e-03	1.00e+00	6.861	1	1	14
GO:0070062	extracellular vesicular exosome	8.95e-03	1.00e+00	1.988	4	43	1641
GO:0044822	poly(A) RNA binding	9.04e-03	1.00e+00	2.611	3	25	799
GO:0006206	pyrimidine nucleobase metabolic process	1.04e-02	1.00e+00	6.581	1	2	17
GO:0071364	cellular response to epidermal growth factor stimulus	1.10e-02	1.00e+00	6.499	1	1	18
GO:0003678	DNA helicase activity	1.10e-02	1.00e+00	6.499	1	3	18
GO:0071339	MLL1 complex	1.10e-02	1.00e+00	6.499	1	2	18
GO:0033574	response to testosterone	1.10e-02	1.00e+00	6.499	1	1	18
GO:0000794	condensed nuclear chromosome	1.10e-02	1.00e+00	6.499	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.22e-02	1.00e+00	6.347	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.22e-02	1.00e+00	6.347	1	2	20
GO:0005524	ATP binding	1.23e-02	1.00e+00	2.453	3	23	892
GO:0017144	drug metabolic process	1.28e-02	1.00e+00	6.276	1	1	21
GO:0043967	histone H4 acetylation	1.34e-02	1.00e+00	6.209	1	2	22
GO:0006096	glycolytic process	1.53e-02	1.00e+00	6.025	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.53e-02	1.00e+00	6.025	1	2	25
GO:0031492	nucleosomal DNA binding	1.53e-02	1.00e+00	6.025	1	2	25
GO:0018107	peptidyl-threonine phosphorylation	1.77e-02	1.00e+00	5.810	1	2	29
GO:0042802	identical protein binding	1.78e-02	1.00e+00	3.201	2	7	354
GO:0006094	gluconeogenesis	1.89e-02	1.00e+00	5.714	1	1	31
GO:0043195	terminal bouton	1.89e-02	1.00e+00	5.714	1	1	31
GO:0007595	lactation	1.95e-02	1.00e+00	5.668	1	2	32
GO:0000226	microtubule cytoskeleton organization	2.19e-02	1.00e+00	5.499	1	2	36
GO:0040008	regulation of growth	2.25e-02	1.00e+00	5.459	1	2	37
GO:0035690	cellular response to drug	2.31e-02	1.00e+00	5.421	1	2	38
GO:0032508	DNA duplex unwinding	2.31e-02	1.00e+00	5.421	1	5	38
GO:0006396	RNA processing	2.43e-02	1.00e+00	5.347	1	1	40
GO:0042995	cell projection	2.49e-02	1.00e+00	5.311	1	2	41
GO:0004386	helicase activity	2.55e-02	1.00e+00	5.276	1	2	42
GO:0031100	organ regeneration	2.67e-02	1.00e+00	5.209	1	2	44
GO:0032481	positive regulation of type I interferon production	2.91e-02	1.00e+00	5.083	1	5	48
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.97e-02	1.00e+00	5.054	1	3	49
GO:0006310	DNA recombination	3.03e-02	1.00e+00	5.025	1	6	50
GO:0006334	nucleosome assembly	3.09e-02	1.00e+00	4.996	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	3.09e-02	1.00e+00	4.996	1	5	51
GO:0005681	spliceosomal complex	3.33e-02	1.00e+00	4.887	1	2	55
GO:0007565	female pregnancy	3.87e-02	1.00e+00	4.668	1	2	64
GO:0005200	structural constituent of cytoskeleton	4.11e-02	1.00e+00	4.581	1	2	68
GO:0030308	negative regulation of cell growth	4.23e-02	1.00e+00	4.539	1	2	70
GO:0006325	chromatin organization	4.23e-02	1.00e+00	4.539	1	3	70
GO:0001889	liver development	4.29e-02	1.00e+00	4.519	1	1	71
GO:0001649	osteoblast differentiation	4.46e-02	1.00e+00	4.459	1	2	74
GO:0005815	microtubule organizing center	4.64e-02	1.00e+00	4.402	1	1	77
GO:0006006	glucose metabolic process	4.82e-02	1.00e+00	4.347	1	1	80
GO:0030529	ribonucleoprotein complex	4.94e-02	1.00e+00	4.311	1	4	82
GO:0005515	protein binding	5.22e-02	1.00e+00	0.981	5	76	4124
GO:0051607	defense response to virus	5.52e-02	1.00e+00	4.145	1	1	92
GO:0000086	G2/M transition of mitotic cell cycle	5.82e-02	1.00e+00	4.069	1	5	97
GO:0009615	response to virus	5.82e-02	1.00e+00	4.069	1	3	97
GO:0016887	ATPase activity	5.99e-02	1.00e+00	4.025	1	6	100
GO:0007507	heart development	6.34e-02	1.00e+00	3.941	1	1	106
GO:0046777	protein autophosphorylation	6.34e-02	1.00e+00	3.941	1	2	106
GO:0000790	nuclear chromatin	6.51e-02	1.00e+00	3.900	1	3	109
GO:0008270	zinc ion binding	6.79e-02	1.00e+00	2.163	2	7	727
GO:0000287	magnesium ion binding	6.86e-02	1.00e+00	3.823	1	2	115
GO:0003924	GTPase activity	7.09e-02	1.00e+00	3.774	1	3	119
GO:0004672	protein kinase activity	7.44e-02	1.00e+00	3.703	1	2	125
GO:0006184	GTP catabolic process	7.73e-02	1.00e+00	3.646	1	3	130
GO:0003714	transcription corepressor activity	8.13e-02	1.00e+00	3.570	1	2	137
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.42e-02	1.00e+00	3.519	1	2	142
GO:0044281	small molecule metabolic process	8.86e-02	1.00e+00	1.947	2	32	844
GO:0005654	nucleoplasm	9.46e-02	1.00e+00	1.894	2	55	876
GO:0008380	RNA splicing	9.72e-02	1.00e+00	3.302	1	7	165
GO:0007067	mitotic nuclear division	9.72e-02	1.00e+00	3.302	1	8	165
GO:0007283	spermatogenesis	9.89e-02	1.00e+00	3.276	1	2	168
GO:0005634	nucleus	9.92e-02	1.00e+00	1.004	4	67	3246
GO:0043025	neuronal cell body	1.01e-01	1.00e+00	3.251	1	3	171
GO:0000166	nucleotide binding	1.03e-01	1.00e+00	3.209	1	6	176
GO:0003677	DNA binding	1.08e-01	1.00e+00	1.781	2	18	947
GO:0005975	carbohydrate metabolic process	1.09e-01	1.00e+00	3.129	1	2	186
GO:0005525	GTP binding	1.15e-01	1.00e+00	3.046	1	5	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.18e-01	1.00e+00	3.003	1	1	203
GO:0006281	DNA repair	1.18e-01	1.00e+00	3.003	1	19	203
GO:0019899	enzyme binding	1.22e-01	1.00e+00	2.954	1	4	210
GO:0007275	multicellular organismal development	1.25e-01	1.00e+00	2.927	1	4	214
GO:0005813	centrosome	1.26e-01	1.00e+00	2.907	1	8	217
GO:0043231	intracellular membrane-bounded organelle	1.27e-01	1.00e+00	2.900	1	7	218
GO:0006351	transcription, DNA-templated	1.35e-01	1.00e+00	1.597	2	9	1076
GO:0003723	RNA binding	1.43e-01	1.00e+00	2.720	1	11	247
GO:0005730	nucleolus	1.66e-01	1.00e+00	1.419	2	41	1217
GO:0000278	mitotic cell cycle	1.78e-01	1.00e+00	2.374	1	35	314
GO:0045892	negative regulation of transcription, DNA-templated	1.80e-01	1.00e+00	2.360	1	7	317
GO:0005737	cytoplasm	2.02e-01	1.00e+00	0.891	3	50	2633
GO:0005783	endoplasmic reticulum	2.12e-01	1.00e+00	2.095	1	3	381
GO:0006915	apoptotic process	2.27e-01	1.00e+00	1.985	1	21	411
GO:0005794	Golgi apparatus	2.29e-01	1.00e+00	1.971	1	5	415
GO:0045087	innate immune response	2.48e-01	1.00e+00	1.848	1	7	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.49e-01	1.00e+00	1.836	1	4	456
GO:0010467	gene expression	2.87e-01	1.00e+00	1.605	1	31	535
GO:0003700	sequence-specific DNA binding transcription factor activity	3.08e-01	1.00e+00	1.484	1	6	582
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.36e-01	1.00e+00	1.338	1	8	644
GO:0005615	extracellular space	3.39e-01	1.00e+00	1.322	1	8	651
GO:0005886	plasma membrane	7.02e-01	1.00e+00	-0.132	1	11	1784

Wolf-ratios-Mammosphere-Adherent

reg-snw-2023

Statistics

Genes (6)

Interactions (5)

Related GO terms (129)