reg-snw-10856

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.956	4.26e-09	1.49e-04	3.92e-04

wolf-screen-ratio-mammosphere-adherent-reg-snw-10856 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	25	0.807	0.973	67	-	-	-
PHB2	11331	8	0.829	0.956	11	-	Yes	-
POLR2F	5435	14	0.891	0.956	5	-	Yes	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
[ RUVBL2 ]	10856	20	0.693	0.956	187	TF	Yes	-
FBL	2091	9	0.839	0.956	14	-	Yes	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
FBL	2091	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
EFTUD2	9343	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	PHB2	11331	pd	>	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot

Related GO terms (173)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016363	nuclear matrix	3.26e-05	3.18e-01	5.479	3	7	73
GO:0000398	mRNA splicing, via spliceosome	1.74e-04	1.00e+00	4.668	3	8	128
GO:0016020	membrane	2.12e-04	1.00e+00	2.431	6	38	1207
GO:0005730	nucleolus	2.22e-04	1.00e+00	2.419	6	41	1217
GO:0015030	Cajal body	3.69e-04	1.00e+00	6.083	2	2	32
GO:0008380	RNA splicing	3.69e-04	1.00e+00	4.302	3	7	165
GO:0005654	nucleoplasm	5.32e-04	1.00e+00	2.631	5	55	876
GO:0043234	protein complex	7.48e-04	1.00e+00	3.954	3	8	210
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	8.68e-04	1.00e+00	5.469	2	3	49
GO:0010467	gene expression	9.00e-04	1.00e+00	3.020	4	31	535
GO:1990259	histone-glutamine methyltransferase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:1990258	histone glutamine methylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004151	dihydroorotase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070335	aspartate binding	9.22e-04	1.00e+00	10.083	1	1	1
GO:0016074	snoRNA metabolic process	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	9.22e-04	1.00e+00	10.083	1	1	1
GO:0005634	nucleus	9.40e-04	1.00e+00	1.419	8	67	3246
GO:0005681	spliceosomal complex	1.09e-03	1.00e+00	5.302	2	2	55
GO:0070062	extracellular vesicular exosome	1.18e-03	1.00e+00	1.988	6	43	1641
GO:0071013	catalytic step 2 spliceosome	1.34e-03	1.00e+00	5.153	2	5	61
GO:0001649	osteoblast differentiation	1.97e-03	1.00e+00	4.874	2	2	74
GO:0071733	transcriptional activation by promoter-enhancer looping	2.76e-03	1.00e+00	8.499	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006543	glutamine catabolic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0001652	granular component	2.76e-03	1.00e+00	8.499	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0031428	box C/D snoRNP complex	2.76e-03	1.00e+00	8.499	1	1	3
GO:0042802	identical protein binding	3.37e-03	1.00e+00	3.201	3	7	354
GO:0051414	response to cortisol	3.68e-03	1.00e+00	8.083	1	1	4
GO:0000212	meiotic spindle organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0071169	establishment of protein localization to chromatin	3.68e-03	1.00e+00	8.083	1	1	4
GO:0006228	UTP biosynthetic process	3.68e-03	1.00e+00	8.083	1	1	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	3.68e-03	1.00e+00	8.083	1	1	4
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	4.60e-03	1.00e+00	7.762	1	1	5
GO:0014075	response to amine	4.60e-03	1.00e+00	7.762	1	1	5
GO:0060744	mammary gland branching involved in thelarche	4.60e-03	1.00e+00	7.762	1	1	5
GO:0005827	polar microtubule	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0003924	GTPase activity	5.01e-03	1.00e+00	4.189	2	3	119
GO:0001055	RNA polymerase II activity	5.52e-03	1.00e+00	7.499	1	2	6
GO:0046134	pyrimidine nucleoside biosynthetic process	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031000	response to caffeine	5.52e-03	1.00e+00	7.499	1	1	6
GO:0006184	GTP catabolic process	5.96e-03	1.00e+00	4.061	2	3	130
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	6.44e-03	1.00e+00	7.276	1	1	7
GO:0000812	Swr1 complex	6.44e-03	1.00e+00	7.276	1	2	7
GO:0031122	cytoplasmic microtubule organization	7.35e-03	1.00e+00	7.083	1	2	8
GO:0031011	Ino80 complex	7.35e-03	1.00e+00	7.083	1	2	8
GO:0008266	poly(U) RNA binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	9.18e-03	1.00e+00	6.762	1	2	10
GO:0006541	glutamine metabolic process	9.18e-03	1.00e+00	6.762	1	1	10
GO:0043968	histone H2A acetylation	9.18e-03	1.00e+00	6.762	1	2	10
GO:0001054	RNA polymerase I activity	9.18e-03	1.00e+00	6.762	1	2	10
GO:0007020	microtubule nucleation	1.01e-02	1.00e+00	6.624	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	2	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0035267	NuA4 histone acetyltransferase complex	1.10e-02	1.00e+00	6.499	1	3	12
GO:0071392	cellular response to estradiol stimulus	1.19e-02	1.00e+00	6.383	1	1	13
GO:0005666	DNA-directed RNA polymerase III complex	1.19e-02	1.00e+00	6.383	1	2	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.19e-02	1.00e+00	6.383	1	2	13
GO:0001056	RNA polymerase III activity	1.19e-02	1.00e+00	6.383	1	2	13
GO:0035066	positive regulation of histone acetylation	1.19e-02	1.00e+00	6.383	1	1	13
GO:0060749	mammary gland alveolus development	1.19e-02	1.00e+00	6.383	1	1	13
GO:0006386	termination of RNA polymerase III transcription	1.28e-02	1.00e+00	6.276	1	2	14
GO:0010243	response to organonitrogen compound	1.28e-02	1.00e+00	6.276	1	1	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.28e-02	1.00e+00	6.276	1	2	14
GO:0005525	GTP binding	1.33e-02	1.00e+00	3.461	2	5	197
GO:0005829	cytosol	1.34e-02	1.00e+00	1.602	5	58	1787
GO:0006281	DNA repair	1.41e-02	1.00e+00	3.418	2	19	203
GO:0005719	nuclear euchromatin	1.47e-02	1.00e+00	6.083	1	1	16
GO:0005839	proteasome core complex	1.47e-02	1.00e+00	6.083	1	9	16
GO:0006206	pyrimidine nucleobase metabolic process	1.56e-02	1.00e+00	5.996	1	2	17
GO:0004298	threonine-type endopeptidase activity	1.56e-02	1.00e+00	5.996	1	9	17
GO:0071364	cellular response to epidermal growth factor stimulus	1.65e-02	1.00e+00	5.914	1	1	18
GO:0003678	DNA helicase activity	1.65e-02	1.00e+00	5.914	1	3	18
GO:0071339	MLL1 complex	1.65e-02	1.00e+00	5.914	1	2	18
GO:0033574	response to testosterone	1.65e-02	1.00e+00	5.914	1	1	18
GO:0000794	condensed nuclear chromosome	1.65e-02	1.00e+00	5.914	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.83e-02	1.00e+00	5.762	1	2	20
GO:0017144	drug metabolic process	1.92e-02	1.00e+00	5.691	1	1	21
GO:0030331	estrogen receptor binding	2.01e-02	1.00e+00	5.624	1	1	22
GO:0043967	histone H4 acetylation	2.01e-02	1.00e+00	5.624	1	2	22
GO:0003723	RNA binding	2.04e-02	1.00e+00	3.135	2	11	247
GO:0006370	7-methylguanosine mRNA capping	2.19e-02	1.00e+00	5.499	1	2	24
GO:0004003	ATP-dependent DNA helicase activity	2.28e-02	1.00e+00	5.440	1	2	25
GO:0008033	tRNA processing	2.28e-02	1.00e+00	5.440	1	1	25
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0031492	nucleosomal DNA binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0006360	transcription from RNA polymerase I promoter	2.46e-02	1.00e+00	5.329	1	2	27
GO:0034644	cellular response to UV	2.55e-02	1.00e+00	5.276	1	2	28
GO:0018107	peptidyl-threonine phosphorylation	2.64e-02	1.00e+00	5.225	1	2	29
GO:0006383	transcription from RNA polymerase III promoter	2.64e-02	1.00e+00	5.225	1	2	29
GO:0043195	terminal bouton	2.82e-02	1.00e+00	5.129	1	1	31
GO:0031490	chromatin DNA binding	2.82e-02	1.00e+00	5.129	1	1	31
GO:0007595	lactation	2.91e-02	1.00e+00	5.083	1	2	32
GO:0014070	response to organic cyclic compound	3.09e-02	1.00e+00	4.996	1	1	34
GO:0044822	poly(A) RNA binding	3.15e-02	1.00e+00	2.026	3	25	799
GO:0050434	positive regulation of viral transcription	3.18e-02	1.00e+00	4.954	1	2	35
GO:0000278	mitotic cell cycle	3.20e-02	1.00e+00	2.789	2	35	314
GO:0000226	microtubule cytoskeleton organization	3.27e-02	1.00e+00	4.914	1	2	36
GO:0040008	regulation of growth	3.36e-02	1.00e+00	4.874	1	2	37
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	76	4124
GO:0035690	cellular response to drug	3.45e-02	1.00e+00	4.836	1	2	38
GO:0032508	DNA duplex unwinding	3.45e-02	1.00e+00	4.836	1	5	38
GO:0006283	transcription-coupled nucleotide-excision repair	3.63e-02	1.00e+00	4.762	1	6	40
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3.63e-02	1.00e+00	4.762	1	2	40
GO:0042995	cell projection	3.72e-02	1.00e+00	4.726	1	2	41
GO:0006521	regulation of cellular amino acid metabolic process	3.72e-02	1.00e+00	4.726	1	16	41
GO:0003684	damaged DNA binding	3.72e-02	1.00e+00	4.726	1	9	41
GO:0031100	organ regeneration	3.98e-02	1.00e+00	4.624	1	2	44
GO:0000502	proteasome complex	4.25e-02	1.00e+00	4.529	1	17	47
GO:0032481	positive regulation of type I interferon production	4.34e-02	1.00e+00	4.499	1	5	48
GO:0006310	DNA recombination	4.52e-02	1.00e+00	4.440	1	6	50
GO:0055086	nucleobase-containing small molecule metabolic process	4.61e-02	1.00e+00	4.411	1	5	51
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.69e-02	1.00e+00	4.383	1	17	52
GO:0006368	transcription elongation from RNA polymerase II promoter	4.69e-02	1.00e+00	4.383	1	3	52
GO:0006289	nucleotide-excision repair	4.78e-02	1.00e+00	4.356	1	9	53
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.78e-02	1.00e+00	4.356	1	17	53
GO:0006338	chromatin remodeling	4.96e-02	1.00e+00	4.302	1	2	55
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.05e-02	1.00e+00	4.276	1	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	5.13e-02	1.00e+00	4.251	1	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.40e-02	1.00e+00	4.177	1	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.49e-02	1.00e+00	4.153	1	16	61
GO:0016032	viral process	5.63e-02	1.00e+00	2.342	2	32	428
GO:0007565	female pregnancy	5.75e-02	1.00e+00	4.083	1	2	64
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.84e-02	1.00e+00	4.061	1	17	65
GO:0006364	rRNA processing	6.01e-02	1.00e+00	4.017	1	4	67
GO:0005200	structural constituent of cytoskeleton	6.10e-02	1.00e+00	3.996	1	2	68
GO:0006325	chromatin organization	6.27e-02	1.00e+00	3.954	1	3	70
GO:0051082	unfolded protein binding	6.27e-02	1.00e+00	3.954	1	4	70
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.27e-02	1.00e+00	3.954	1	16	70
GO:0001889	liver development	6.36e-02	1.00e+00	3.934	1	1	71
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	4	82
GO:0000209	protein polyubiquitination	8.17e-02	1.00e+00	3.560	1	16	92
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	5	97
GO:0006457	protein folding	8.60e-02	1.00e+00	3.484	1	4	97
GO:0016887	ATPase activity	8.85e-02	1.00e+00	3.440	1	6	100
GO:0034641	cellular nitrogen compound metabolic process	9.28e-02	1.00e+00	3.369	1	18	105
GO:0007507	heart development	9.36e-02	1.00e+00	3.356	1	1	106
GO:0046777	protein autophosphorylation	9.36e-02	1.00e+00	3.356	1	2	106
GO:0000790	nuclear chromatin	9.61e-02	1.00e+00	3.315	1	3	109
GO:0006397	mRNA processing	9.70e-02	1.00e+00	3.302	1	2	110
GO:0042981	regulation of apoptotic process	9.87e-02	1.00e+00	3.276	1	18	112
GO:0016607	nuclear speck	1.07e-01	1.00e+00	3.153	1	3	122
GO:0004672	protein kinase activity	1.10e-01	1.00e+00	3.118	1	2	125
GO:0000082	G1/S transition of mitotic cell cycle	1.10e-01	1.00e+00	3.118	1	24	125
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	2	142
GO:0005622	intracellular	1.26e-01	1.00e+00	2.904	1	1	145
GO:0006367	transcription initiation from RNA polymerase II promoter	1.39e-01	1.00e+00	2.753	1	4	161
GO:0016071	mRNA metabolic process	1.46e-01	1.00e+00	2.674	1	21	170
GO:0043025	neuronal cell body	1.47e-01	1.00e+00	2.666	1	3	171
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	6	176
GO:0016070	RNA metabolic process	1.61e-01	1.00e+00	2.529	1	21	188
GO:0005743	mitochondrial inner membrane	1.68e-01	1.00e+00	2.461	1	3	197
GO:0019899	enzyme binding	1.78e-01	1.00e+00	2.369	1	4	210
GO:0044281	small molecule metabolic process	1.79e-01	1.00e+00	1.362	2	32	844
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	8	217
GO:0006200	ATP catabolic process	1.85e-01	1.00e+00	2.309	1	8	219
GO:0005524	ATP binding	1.96e-01	1.00e+00	1.283	2	23	892
GO:0045892	negative regulation of transcription, DNA-templated	2.57e-01	1.00e+00	1.775	1	7	317
GO:0006351	transcription, DNA-templated	2.61e-01	1.00e+00	1.012	2	9	1076
GO:0043066	negative regulation of apoptotic process	2.61e-01	1.00e+00	1.753	1	20	322
GO:0006366	transcription from RNA polymerase II promoter	2.74e-01	1.00e+00	1.670	1	6	341
GO:0006915	apoptotic process	3.21e-01	1.00e+00	1.400	1	21	411
GO:0045087	innate immune response	3.47e-01	1.00e+00	1.263	1	7	452
GO:0005737	cytoplasm	4.54e-01	1.00e+00	0.306	3	50	2633
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.59e-01	1.00e+00	0.753	1	8	644
GO:0005739	mitochondrion	4.67e-01	1.00e+00	0.719	1	11	659
GO:0008270	zinc ion binding	5.02e-01	1.00e+00	0.578	1	7	727
GO:0003677	DNA binding	6.01e-01	1.00e+00	0.196	1	18	947

Wolf-ratios-Mammosphere-Adherent

reg-snw-10856

Statistics

Genes (9)

Interactions (8)

Related GO terms (173)