reg-snw-7019

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.848	4.36e-07	1.94e-03	3.85e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-7019 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
[ TFAM ]	7019	1	0.169	0.848	154	TF	-	-
RAN	5901	8	0.632	0.899	83	-	Yes	-
HSPD1	3329	4	0.913	0.875	39	-	Yes	-
RRM1	6240	3	0.587	0.872	78	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPC	3183	TFAM	7019	pd	<	reg.ITFP.txt: no annot
RAN	5901	TFAM	7019	pd	<	reg.ITFP.txt: no annot
HSPD1	3329	TFAM	7019	pd	<	reg.ITFP.txt: no annot
RRM1	6240	TFAM	7019	pd	<	reg.ITFP.txt: no annot
TFAM	7019	TUBG1	7283	pd	>	reg.ITFP.txt: no annot

Related GO terms (136)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0044822	poly(A) RNA binding	5.84e-04	1.00e+00	3.026	4	25	799
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	6.14e-04	1.00e+00	10.668	1	1	1
GO:0048291	isotype switching to IgG isotypes	6.14e-04	1.00e+00	10.668	1	1	1
GO:0033108	mitochondrial respiratory chain complex assembly	6.14e-04	1.00e+00	10.668	1	1	1
GO:0002368	B cell cytokine production	6.14e-04	1.00e+00	10.668	1	1	1
GO:0005829	cytosol	1.04e-03	1.00e+00	2.187	5	58	1787
GO:0009263	deoxyribonucleotide biosynthetic process	1.23e-03	1.00e+00	9.668	1	1	2
GO:0006458	'de novo' protein folding	1.23e-03	1.00e+00	9.668	1	1	2
GO:0070363	mitochondrial light strand promoter sense binding	1.23e-03	1.00e+00	9.668	1	1	2
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	1.23e-03	1.00e+00	9.668	1	1	2
GO:0006391	transcription initiation from mitochondrial promoter	1.84e-03	1.00e+00	9.083	1	1	3
GO:0003688	DNA replication origin binding	1.84e-03	1.00e+00	9.083	1	1	3
GO:0046696	lipopolysaccharide receptor complex	1.84e-03	1.00e+00	9.083	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	1.84e-03	1.00e+00	9.083	1	1	3
GO:0030135	coated vesicle	1.84e-03	1.00e+00	9.083	1	1	3
GO:0003924	GTPase activity	2.14e-03	1.00e+00	4.774	2	3	119
GO:0000212	meiotic spindle organization	2.46e-03	1.00e+00	8.668	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	2.46e-03	1.00e+00	8.668	1	1	4
GO:0006184	GTP catabolic process	2.55e-03	1.00e+00	4.646	2	3	130
GO:0010467	gene expression	2.89e-03	1.00e+00	3.190	3	31	535
GO:0005759	mitochondrial matrix	2.91e-03	1.00e+00	4.550	2	5	139
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0005827	polar microtubule	3.07e-03	1.00e+00	8.347	1	1	5
GO:0006356	regulation of transcription from RNA polymerase I promoter	3.07e-03	1.00e+00	8.347	1	1	5
GO:0000930	gamma-tubulin complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0006390	transcription from mitochondrial promoter	3.68e-03	1.00e+00	8.083	1	1	6
GO:0043032	positive regulation of macrophage activation	3.68e-03	1.00e+00	8.083	1	1	6
GO:0075733	intracellular transport of virus	4.29e-03	1.00e+00	7.861	1	1	7
GO:0031122	cytoplasmic microtubule organization	4.91e-03	1.00e+00	7.668	1	2	8
GO:0032727	positive regulation of interferon-alpha production	4.91e-03	1.00e+00	7.668	1	1	8
GO:0051290	protein heterotetramerization	4.91e-03	1.00e+00	7.668	1	1	8
GO:0051604	protein maturation	4.91e-03	1.00e+00	7.668	1	1	8
GO:0021846	cell proliferation in forebrain	5.52e-03	1.00e+00	7.499	1	1	9
GO:0001530	lipopolysaccharide binding	5.52e-03	1.00e+00	7.499	1	1	9
GO:0008266	poly(U) RNA binding	5.52e-03	1.00e+00	7.499	1	1	9
GO:0005515	protein binding	5.66e-03	1.00e+00	1.244	6	76	4124
GO:0005525	GTP binding	5.76e-03	1.00e+00	4.046	2	5	197
GO:0006261	DNA-dependent DNA replication	6.13e-03	1.00e+00	7.347	1	2	10
GO:0042026	protein refolding	6.13e-03	1.00e+00	7.347	1	1	10
GO:0051131	chaperone-mediated protein complex assembly	6.13e-03	1.00e+00	7.347	1	1	10
GO:0043234	protein complex	6.52e-03	1.00e+00	3.954	2	8	210
GO:0007020	microtubule nucleation	6.74e-03	1.00e+00	7.209	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	6.74e-03	1.00e+00	7.209	1	2	11
GO:0045120	pronucleus	6.74e-03	1.00e+00	7.209	1	1	11
GO:0015949	nucleobase-containing small molecule interconversion	7.35e-03	1.00e+00	7.083	1	2	12
GO:0032733	positive regulation of interleukin-10 production	7.96e-03	1.00e+00	6.968	1	1	13
GO:0006259	DNA metabolic process	8.57e-03	1.00e+00	6.861	1	3	14
GO:0050870	positive regulation of T cell activation	8.57e-03	1.00e+00	6.861	1	1	14
GO:0070062	extracellular vesicular exosome	8.95e-03	1.00e+00	1.988	4	43	1641
GO:0008301	DNA binding, bending	9.18e-03	1.00e+00	6.762	1	1	15
GO:0003682	chromatin binding	9.29e-03	1.00e+00	3.691	2	6	252
GO:0042113	B cell activation	9.79e-03	1.00e+00	6.668	1	1	16
GO:0006206	pyrimidine nucleobase metabolic process	1.04e-02	1.00e+00	6.581	1	2	17
GO:0042100	B cell proliferation	1.04e-02	1.00e+00	6.581	1	1	17
GO:0007052	mitotic spindle organization	1.04e-02	1.00e+00	6.581	1	2	17
GO:0006611	protein export from nucleus	1.10e-02	1.00e+00	6.499	1	2	18
GO:0000794	condensed nuclear chromosome	1.10e-02	1.00e+00	6.499	1	3	18
GO:0005654	nucleoplasm	1.17e-02	1.00e+00	2.479	3	55	876
GO:0043044	ATP-dependent chromatin remodeling	1.22e-02	1.00e+00	6.347	1	2	20
GO:0032735	positive regulation of interleukin-12 production	1.22e-02	1.00e+00	6.347	1	1	20
GO:0007286	spermatid development	1.41e-02	1.00e+00	6.145	1	1	23
GO:0000278	mitotic cell cycle	1.42e-02	1.00e+00	3.374	2	35	314
GO:0003730	mRNA 3'-UTR binding	1.53e-02	1.00e+00	6.025	1	2	25
GO:0031492	nucleosomal DNA binding	1.53e-02	1.00e+00	6.025	1	2	25
GO:0032755	positive regulation of interleukin-6 production	1.65e-02	1.00e+00	5.914	1	1	27
GO:0032729	positive regulation of interferon-gamma production	1.71e-02	1.00e+00	5.861	1	1	28
GO:0031072	heat shock protein binding	1.71e-02	1.00e+00	5.861	1	2	28
GO:0050681	androgen receptor binding	1.83e-02	1.00e+00	5.762	1	2	30
GO:0010212	response to ionizing radiation	1.83e-02	1.00e+00	5.762	1	1	30
GO:0042645	mitochondrial nucleoid	1.89e-02	1.00e+00	5.714	1	1	31
GO:0042110	T cell activation	2.01e-02	1.00e+00	5.624	1	1	33
GO:0045893	positive regulation of transcription, DNA-templated	2.01e-02	1.00e+00	3.110	2	10	377
GO:0019003	GDP binding	2.07e-02	1.00e+00	5.581	1	1	34
GO:0032092	positive regulation of protein binding	2.07e-02	1.00e+00	5.581	1	1	34
GO:0060041	retina development in camera-type eye	2.07e-02	1.00e+00	5.581	1	2	34
GO:0006986	response to unfolded protein	2.13e-02	1.00e+00	5.539	1	1	35
GO:0030521	androgen receptor signaling pathway	2.13e-02	1.00e+00	5.539	1	2	35
GO:0000226	microtubule cytoskeleton organization	2.19e-02	1.00e+00	5.499	1	2	36
GO:0005905	coated pit	2.25e-02	1.00e+00	5.459	1	2	37
GO:0042995	cell projection	2.49e-02	1.00e+00	5.311	1	2	41
GO:0016032	viral process	2.56e-02	1.00e+00	2.927	2	32	428
GO:0030141	secretory granule	2.67e-02	1.00e+00	5.209	1	1	44
GO:0051087	chaperone binding	2.73e-02	1.00e+00	5.177	1	3	45
GO:0003725	double-stranded RNA binding	2.73e-02	1.00e+00	5.177	1	3	45
GO:0002039	p53 binding	2.73e-02	1.00e+00	5.177	1	2	45
GO:0016020	membrane	2.82e-02	1.00e+00	2.016	3	38	1207
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.97e-02	1.00e+00	5.054	1	3	49
GO:0005643	nuclear pore	3.09e-02	1.00e+00	4.996	1	2	51
GO:0055086	nucleobase-containing small molecule metabolic process	3.09e-02	1.00e+00	4.996	1	5	51
GO:0005681	spliceosomal complex	3.33e-02	1.00e+00	4.887	1	2	55
GO:0008584	male gonad development	3.45e-02	1.00e+00	4.836	1	2	57
GO:0003697	single-stranded DNA binding	3.45e-02	1.00e+00	4.836	1	6	57
GO:0000785	chromatin	3.57e-02	1.00e+00	4.786	1	5	59
GO:0071013	catalytic step 2 spliceosome	3.69e-02	1.00e+00	4.738	1	5	61
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3.69e-02	1.00e+00	4.738	1	1	61
GO:0042470	melanosome	3.87e-02	1.00e+00	4.668	1	2	64
GO:0050821	protein stabilization	3.87e-02	1.00e+00	4.668	1	1	64
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	4.05e-02	1.00e+00	4.602	1	2	67
GO:0005200	structural constituent of cytoskeleton	4.11e-02	1.00e+00	4.581	1	2	68
GO:0051082	unfolded protein binding	4.23e-02	1.00e+00	4.539	1	4	70
GO:0001649	osteoblast differentiation	4.46e-02	1.00e+00	4.459	1	2	74
GO:0019058	viral life cycle	4.70e-02	1.00e+00	4.383	1	3	78
GO:0005737	cytoplasm	4.89e-02	1.00e+00	1.306	4	50	2633
GO:0005635	nuclear envelope	4.99e-02	1.00e+00	4.293	1	4	83
GO:0006260	DNA replication	5.64e-02	1.00e+00	4.114	1	11	94
GO:0005739	mitochondrion	5.69e-02	1.00e+00	2.304	2	11	659
GO:0000086	G2/M transition of mitotic cell cycle	5.82e-02	1.00e+00	4.069	1	5	97
GO:0016887	ATPase activity	5.99e-02	1.00e+00	4.025	1	6	100
GO:0005769	early endosome	6.51e-02	1.00e+00	3.900	1	1	109
GO:0000790	nuclear chromatin	6.51e-02	1.00e+00	3.900	1	3	109
GO:0000398	mRNA splicing, via spliceosome	7.61e-02	1.00e+00	3.668	1	8	128
GO:0019904	protein domain specific binding	7.73e-02	1.00e+00	3.646	1	2	130
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.42e-02	1.00e+00	3.519	1	2	142
GO:0044281	small molecule metabolic process	8.86e-02	1.00e+00	1.947	2	32	844
GO:0008380	RNA splicing	9.72e-02	1.00e+00	3.302	1	7	165
GO:0007067	mitotic nuclear division	9.72e-02	1.00e+00	3.302	1	8	165
GO:0005524	ATP binding	9.76e-02	1.00e+00	1.868	2	23	892
GO:0043025	neuronal cell body	1.01e-01	1.00e+00	3.251	1	3	171
GO:0007264	small GTPase mediated signal transduction	1.02e-01	1.00e+00	3.225	1	1	174
GO:0000166	nucleotide binding	1.03e-01	1.00e+00	3.209	1	6	176
GO:0003713	transcription coactivator activity	1.08e-01	1.00e+00	3.145	1	5	184
GO:0005743	mitochondrial inner membrane	1.15e-01	1.00e+00	3.046	1	3	197
GO:0043065	positive regulation of apoptotic process	1.18e-01	1.00e+00	3.010	1	3	202
GO:0005813	centrosome	1.26e-01	1.00e+00	2.907	1	8	217
GO:0006200	ATP catabolic process	1.27e-01	1.00e+00	2.894	1	8	219
GO:0003723	RNA binding	1.43e-01	1.00e+00	2.720	1	11	247
GO:0009986	cell surface	1.66e-01	1.00e+00	2.484	1	2	291
GO:0055114	oxidation-reduction process	1.75e-01	1.00e+00	2.402	1	3	308
GO:0043066	negative regulation of apoptotic process	1.82e-01	1.00e+00	2.338	1	20	322
GO:0042802	identical protein binding	1.99e-01	1.00e+00	2.201	1	7	354
GO:0003700	sequence-specific DNA binding transcription factor activity	3.08e-01	1.00e+00	1.484	1	6	582
GO:0005634	nucleus	3.18e-01	1.00e+00	0.589	3	67	3246
GO:0007165	signal transduction	3.25e-01	1.00e+00	1.397	1	5	618
GO:0005615	extracellular space	3.39e-01	1.00e+00	1.322	1	8	651
GO:0005730	nucleolus	5.50e-01	1.00e+00	0.419	1	41	1217
GO:0005886	plasma membrane	7.02e-01	1.00e+00	-0.132	1	11	1784

Wolf-ratios-Mammosphere-Adherent

reg-snw-7019

Statistics

Genes (6)

Interactions (5)

Related GO terms (136)