reg-snw-6119

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.901	4.92e-08	5.88e-04	1.33e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-6119 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
PSMB1	5689	5	0.688	0.901	28	-	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-
[ RPA3 ]	6119	1	0.475	0.901	72	TF	Yes	-
PSMB3	5691	2	0.668	0.901	19	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	RPA3	6119	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	RPA3	6119	pd	<	reg.ITFP.txt: no annot
RPA3	6119	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB3	5691	RPA3	6119	pd	<	reg.ITFP.txt: no annot

Related GO terms (114)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000082	G1/S transition of mitotic cell cycle	6.53e-09	6.37e-05	5.802	5	24	125
GO:0006521	regulation of cellular amino acid metabolic process	9.28e-09	9.06e-05	7.088	4	16	41
GO:0000502	proteasome complex	1.63e-08	1.59e-04	6.891	4	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.47e-08	2.42e-04	6.746	4	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.67e-08	2.61e-04	6.718	4	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.35e-08	3.27e-04	6.639	4	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.60e-08	3.52e-04	6.613	4	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.45e-08	4.34e-04	6.539	4	17	60
GO:0005654	nucleoplasm	4.57e-08	4.47e-04	3.479	7	55	876
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.76e-08	4.64e-04	6.515	4	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.17e-08	6.02e-04	6.424	4	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	8.34e-08	8.14e-04	6.317	4	16	70
GO:0005839	proteasome core complex	1.26e-07	1.23e-03	8.031	3	9	16
GO:0004298	threonine-type endopeptidase activity	1.53e-07	1.49e-03	7.944	3	9	17
GO:0000209	protein polyubiquitination	2.53e-07	2.47e-03	5.922	4	16	92
GO:0034641	cellular nitrogen compound metabolic process	4.31e-07	4.21e-03	5.732	4	18	105
GO:0042981	regulation of apoptotic process	5.59e-07	5.46e-03	5.639	4	18	112
GO:0000278	mitotic cell cycle	6.63e-07	6.48e-03	4.473	5	35	314
GO:0016071	mRNA metabolic process	2.98e-06	2.91e-02	5.037	4	21	170
GO:0016070	RNA metabolic process	4.45e-06	4.35e-02	4.891	4	21	188
GO:0010467	gene expression	9.28e-06	9.07e-02	3.705	5	31	535
GO:0043066	negative regulation of apoptotic process	3.75e-05	3.67e-01	4.115	4	20	322
GO:0006915	apoptotic process	9.78e-05	9.55e-01	3.763	4	21	411
GO:0016032	viral process	1.15e-04	1.00e+00	3.705	4	32	428
GO:0070062	extracellular vesicular exosome	1.34e-04	1.00e+00	2.351	6	43	1641
GO:0003684	damaged DNA binding	3.56e-04	1.00e+00	6.088	2	9	41
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	5.10e-04	1.00e+00	5.831	2	3	49
GO:0044281	small molecule metabolic process	1.57e-03	1.00e+00	2.725	4	32	844
GO:0071733	transcriptional activation by promoter-enhancer looping	2.15e-03	1.00e+00	8.861	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	2.15e-03	1.00e+00	8.861	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	2.15e-03	1.00e+00	8.861	1	1	3
GO:0005515	protein binding	2.39e-03	1.00e+00	1.244	7	76	4124
GO:0071169	establishment of protein localization to chromatin	2.86e-03	1.00e+00	8.446	1	1	4
GO:0043248	proteasome assembly	2.86e-03	1.00e+00	8.446	1	1	4
GO:0005829	cytosol	3.09e-03	1.00e+00	1.965	5	58	1787
GO:0000730	DNA recombinase assembly	3.58e-03	1.00e+00	8.124	1	3	5
GO:0000812	Swr1 complex	5.01e-03	1.00e+00	7.639	1	2	7
GO:0005662	DNA replication factor A complex	5.72e-03	1.00e+00	7.446	1	3	8
GO:0031011	Ino80 complex	5.72e-03	1.00e+00	7.446	1	2	8
GO:0016020	membrane	5.97e-03	1.00e+00	2.209	4	38	1207
GO:0008266	poly(U) RNA binding	6.44e-03	1.00e+00	7.276	1	1	9
GO:0005634	nucleus	6.74e-03	1.00e+00	1.367	6	67	3246
GO:0043968	histone H2A acetylation	7.15e-03	1.00e+00	7.124	1	2	10
GO:0005838	proteasome regulatory particle	7.15e-03	1.00e+00	7.124	1	4	10
GO:0045120	pronucleus	7.86e-03	1.00e+00	6.987	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	7.86e-03	1.00e+00	6.987	1	2	11
GO:0006281	DNA repair	8.43e-03	1.00e+00	3.781	2	19	203
GO:0035267	NuA4 histone acetyltransferase complex	8.57e-03	1.00e+00	6.861	1	3	12
GO:0048863	stem cell differentiation	8.57e-03	1.00e+00	6.861	1	1	12
GO:0035066	positive regulation of histone acetylation	9.28e-03	1.00e+00	6.746	1	1	13
GO:0071392	cellular response to estradiol stimulus	9.28e-03	1.00e+00	6.746	1	1	13
GO:0010243	response to organonitrogen compound	1.00e-02	1.00e+00	6.639	1	1	14
GO:0022624	proteasome accessory complex	1.00e-02	1.00e+00	6.639	1	7	14
GO:0005719	nuclear euchromatin	1.14e-02	1.00e+00	6.446	1	1	16
GO:0006298	mismatch repair	1.21e-02	1.00e+00	6.359	1	4	17
GO:0000718	nucleotide-excision repair, DNA damage removal	1.21e-02	1.00e+00	6.359	1	5	17
GO:0071339	MLL1 complex	1.28e-02	1.00e+00	6.276	1	2	18
GO:0006297	nucleotide-excision repair, DNA gap filling	1.28e-02	1.00e+00	6.276	1	5	18
GO:0003678	DNA helicase activity	1.28e-02	1.00e+00	6.276	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.43e-02	1.00e+00	6.124	1	2	20
GO:0032201	telomere maintenance via semi-conservative replication	1.43e-02	1.00e+00	6.124	1	7	20
GO:0007346	regulation of mitotic cell cycle	1.50e-02	1.00e+00	6.054	1	2	21
GO:0043967	histone H4 acetylation	1.57e-02	1.00e+00	5.987	1	2	22
GO:0000722	telomere maintenance via recombination	1.57e-02	1.00e+00	5.987	1	7	22
GO:0004003	ATP-dependent DNA helicase activity	1.78e-02	1.00e+00	5.802	1	2	25
GO:0031492	nucleosomal DNA binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0034644	cellular response to UV	1.99e-02	1.00e+00	5.639	1	2	28
GO:0006271	DNA strand elongation involved in DNA replication	2.06e-02	1.00e+00	5.588	1	8	29
GO:0031490	chromatin DNA binding	2.20e-02	1.00e+00	5.492	1	1	31
GO:0006284	base-excision repair	2.27e-02	1.00e+00	5.446	1	8	32
GO:0014070	response to organic cyclic compound	2.41e-02	1.00e+00	5.359	1	1	34
GO:0042802	identical protein binding	2.44e-02	1.00e+00	2.978	2	7	354
GO:0040008	regulation of growth	2.62e-02	1.00e+00	5.237	1	2	37
GO:0032508	DNA duplex unwinding	2.69e-02	1.00e+00	5.198	1	5	38
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2.83e-02	1.00e+00	5.124	1	2	40
GO:0006283	transcription-coupled nucleotide-excision repair	2.83e-02	1.00e+00	5.124	1	6	40
GO:0000724	double-strand break repair via homologous recombination	2.97e-02	1.00e+00	5.054	1	5	42
GO:0000723	telomere maintenance	3.32e-02	1.00e+00	4.891	1	8	47
GO:0006310	DNA recombination	3.53e-02	1.00e+00	4.802	1	6	50
GO:0006302	double-strand break repair	3.67e-02	1.00e+00	4.746	1	8	52
GO:0006289	nucleotide-excision repair	3.74e-02	1.00e+00	4.718	1	9	53
GO:0005681	spliceosomal complex	3.88e-02	1.00e+00	4.665	1	2	55
GO:0006338	chromatin remodeling	3.88e-02	1.00e+00	4.665	1	2	55
GO:0003697	single-stranded DNA binding	4.02e-02	1.00e+00	4.613	1	6	57
GO:0071013	catalytic step 2 spliceosome	4.29e-02	1.00e+00	4.515	1	5	61
GO:0005730	nucleolus	4.59e-02	1.00e+00	1.782	3	41	1217
GO:0006325	chromatin organization	4.91e-02	1.00e+00	4.317	1	3	70
GO:0051082	unfolded protein binding	4.91e-02	1.00e+00	4.317	1	4	70
GO:0016363	nuclear matrix	5.12e-02	1.00e+00	4.256	1	7	73
GO:0001649	osteoblast differentiation	5.19e-02	1.00e+00	4.237	1	2	74
GO:0042127	regulation of cell proliferation	5.60e-02	1.00e+00	4.124	1	3	80
GO:0030529	ribonucleoprotein complex	5.73e-02	1.00e+00	4.088	1	4	82
GO:0006511	ubiquitin-dependent protein catabolic process	6.41e-02	1.00e+00	3.922	1	2	92
GO:0006260	DNA replication	6.55e-02	1.00e+00	3.891	1	11	94
GO:0006457	protein folding	6.75e-02	1.00e+00	3.846	1	4	97
GO:0016887	ATPase activity	6.95e-02	1.00e+00	3.802	1	6	100
GO:0000790	nuclear chromatin	7.56e-02	1.00e+00	3.678	1	3	109
GO:0000398	mRNA splicing, via spliceosome	8.83e-02	1.00e+00	3.446	1	8	128
GO:0015629	actin cytoskeleton	9.35e-02	1.00e+00	3.359	1	2	136
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.75e-02	1.00e+00	3.296	1	2	142
GO:0005622	intracellular	9.95e-02	1.00e+00	3.266	1	1	145
GO:0008380	RNA splicing	1.12e-01	1.00e+00	3.080	1	7	165
GO:0000166	nucleotide binding	1.20e-01	1.00e+00	2.987	1	6	176
GO:0043234	protein complex	1.41e-01	1.00e+00	2.732	1	8	210
GO:0006200	ATP catabolic process	1.47e-01	1.00e+00	2.671	1	8	219
GO:0003723	RNA binding	1.64e-01	1.00e+00	2.498	1	11	247
GO:0005794	Golgi apparatus	2.62e-01	1.00e+00	1.749	1	5	415
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.115	1	8	644
GO:0005739	mitochondrion	3.87e-01	1.00e+00	1.082	1	11	659
GO:0044822	poly(A) RNA binding	4.50e-01	1.00e+00	0.804	1	25	799
GO:0005524	ATP binding	4.89e-01	1.00e+00	0.645	1	23	892
GO:0006351	transcription, DNA-templated	5.58e-01	1.00e+00	0.375	1	9	1076
GO:0005737	cytoplasm	6.03e-01	1.00e+00	0.084	2	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-6119

Statistics

Genes (7)

Interactions (8)

Related GO terms (114)