reg-snw-5693

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.801	2.58e-06	4.98e-03	8.96e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-5693 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ PSMB5 ]	5693	1	0.103	0.801	18	-	-	-
PFDN2	5202	2	0.837	0.854	34	TF	Yes	-
PSMD6	9861	2	0.848	0.878	12	TF	Yes	-
PSMD13	5719	1	0.848	0.801	10	TF	Yes	-
RBX1	9978	8	1.185	0.934	9	TF	Yes	-
PSMB7	5695	10	0.982	0.934	33	-	Yes	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	PSMD13	5719	pd	<	reg.ITFP.txt: no annot
PFDN2	5202	PSMB7	5695	pd	>	reg.ITFP.txt: no annot
PSMB7	5695	PSMD6	9861	pd	<	reg.ITFP.txt: no annot
PFDN2	5202	PSMB5	5693	pd	>	reg.ITFP.txt: no annot

Related GO terms (70)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	3.99e-09	3.89e-05	7.311	4	16	41
GO:0000502	proteasome complex	7.02e-09	6.85e-05	7.114	4	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.06e-08	1.04e-04	6.968	4	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.15e-08	1.12e-04	6.941	4	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.44e-08	1.41e-04	6.861	4	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.55e-08	1.51e-04	6.836	4	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.91e-08	1.87e-04	6.762	4	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.05e-08	2.00e-04	6.738	4	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.66e-08	2.59e-04	6.646	4	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.59e-08	3.51e-04	6.539	4	16	70
GO:0000209	protein polyubiquitination	1.09e-07	1.07e-03	6.145	4	16	92
GO:0034641	cellular nitrogen compound metabolic process	1.86e-07	1.82e-03	5.954	4	18	105
GO:0042981	regulation of apoptotic process	2.42e-07	2.36e-03	5.861	4	18	112
GO:0000082	G1/S transition of mitotic cell cycle	3.76e-07	3.68e-03	5.703	4	24	125
GO:0016032	viral process	9.15e-07	8.93e-03	4.249	5	32	428
GO:0016071	mRNA metabolic process	1.29e-06	1.26e-02	5.259	4	21	170
GO:0016070	RNA metabolic process	1.94e-06	1.89e-02	5.114	4	21	188
GO:0000278	mitotic cell cycle	1.50e-05	1.46e-01	4.374	4	35	314
GO:0043066	negative regulation of apoptotic process	1.65e-05	1.61e-01	4.338	4	20	322
GO:0022624	proteasome accessory complex	2.85e-05	2.79e-01	7.861	2	7	14
GO:0005654	nucleoplasm	3.19e-05	3.12e-01	3.216	5	55	876
GO:0005839	proteasome core complex	3.76e-05	3.67e-01	7.668	2	9	16
GO:0004298	threonine-type endopeptidase activity	4.26e-05	4.16e-01	7.581	2	9	17
GO:0006915	apoptotic process	4.34e-05	4.24e-01	3.985	4	21	411
GO:0010467	gene expression	1.22e-04	1.00e+00	3.605	4	31	535
GO:0070062	extracellular vesicular exosome	6.88e-04	1.00e+00	2.310	5	43	1641
GO:0044281	small molecule metabolic process	7.21e-04	1.00e+00	2.947	4	32	844
GO:0005829	cytosol	1.04e-03	1.00e+00	2.187	5	58	1787
GO:0007127	meiosis I	1.23e-03	1.00e+00	9.668	1	1	2
GO:0030891	VCB complex	1.23e-03	1.00e+00	9.668	1	1	2
GO:0031467	Cul7-RING ubiquitin ligase complex	1.23e-03	1.00e+00	9.668	1	1	2
GO:0019788	NEDD8 ligase activity	2.46e-03	1.00e+00	8.668	1	1	4
GO:0031461	cullin-RING ubiquitin ligase complex	2.46e-03	1.00e+00	8.668	1	2	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	3.07e-03	1.00e+00	8.347	1	2	5
GO:0016272	prefoldin complex	3.68e-03	1.00e+00	8.083	1	1	6
GO:0031462	Cul2-RING ubiquitin ligase complex	3.68e-03	1.00e+00	8.083	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	3.68e-03	1.00e+00	8.083	1	1	6
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	4.29e-03	1.00e+00	7.861	1	2	7
GO:0045116	protein neddylation	4.29e-03	1.00e+00	7.861	1	1	7
GO:0005838	proteasome regulatory particle	6.13e-03	1.00e+00	7.347	1	4	10
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	9.79e-03	1.00e+00	6.668	1	1	16
GO:0031463	Cul3-RING ubiquitin ligase complex	9.79e-03	1.00e+00	6.668	1	1	16
GO:0006513	protein monoubiquitination	1.04e-02	1.00e+00	6.581	1	1	17
GO:0019005	SCF ubiquitin ligase complex	1.22e-02	1.00e+00	6.347	1	1	20
GO:0051084	'de novo' posttranslational protein folding	1.34e-02	1.00e+00	6.209	1	2	22
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.34e-02	1.00e+00	6.209	1	1	22
GO:0005730	nucleolus	2.89e-02	1.00e+00	2.004	3	41	1217
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	3.39e-02	1.00e+00	4.861	1	3	56
GO:0006979	response to oxidative stress	3.87e-02	1.00e+00	4.668	1	1	64
GO:0051082	unfolded protein binding	4.23e-02	1.00e+00	4.539	1	4	70
GO:0015630	microtubule cytoskeleton	4.52e-02	1.00e+00	4.440	1	2	75
GO:0071456	cellular response to hypoxia	4.58e-02	1.00e+00	4.421	1	2	76
GO:0007219	Notch signaling pathway	5.70e-02	1.00e+00	4.099	1	4	95
GO:0006457	protein folding	5.82e-02	1.00e+00	4.069	1	4	97
GO:0016887	ATPase activity	5.99e-02	1.00e+00	4.025	1	6	100
GO:0032403	protein complex binding	7.73e-02	1.00e+00	3.646	1	2	130
GO:0031625	ubiquitin protein ligase binding	8.19e-02	1.00e+00	3.560	1	5	138
GO:0005634	nucleus	9.92e-02	1.00e+00	1.004	4	67	3246
GO:0004842	ubiquitin-protein transferase activity	1.05e-01	1.00e+00	3.185	1	2	179
GO:0016567	protein ubiquitination	1.10e-01	1.00e+00	3.114	1	3	188
GO:0006281	DNA repair	1.18e-01	1.00e+00	3.003	1	19	203
GO:0006200	ATP catabolic process	1.27e-01	1.00e+00	2.894	1	8	219
GO:0006508	proteolysis	1.52e-01	1.00e+00	2.624	1	3	264
GO:0044267	cellular protein metabolic process	1.98e-01	1.00e+00	2.209	1	5	352
GO:0005515	protein binding	2.11e-01	1.00e+00	0.659	4	76	4124
GO:0005794	Golgi apparatus	2.29e-01	1.00e+00	1.971	1	5	415
GO:0005739	mitochondrion	3.43e-01	1.00e+00	1.304	1	11	659
GO:0008270	zinc ion binding	3.71e-01	1.00e+00	1.163	1	7	727
GO:0016020	membrane	5.47e-01	1.00e+00	0.431	1	38	1207
GO:0005737	cytoplasm	8.48e-01	1.00e+00	-0.694	1	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-5693

Statistics

Genes (6)

Interactions (5)

Related GO terms (70)