reg-snw-4751

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.799	2.70e-06	5.11e-03	9.15e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-4751 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
CAD	790	25	0.807	0.973	67	-	-	-
CCNA2	890	10	0.550	0.973	246	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
CAND1	55832	1	0.566	0.799	30	TF	-	-
[ NEK2 ]	4751	1	0.165	0.799	42	-	-	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CCNA2	890	NEK2	4751	pd	>	reg.ITFP.txt: no annot
NEK2	4751	CAND1	55832	pd	<	reg.ITFP.txt: no annot
CCNA2	890	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot

Related GO terms (142)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000086	G2/M transition of mitotic cell cycle	3.23e-05	3.16e-01	5.431	3	5	97
GO:0000794	condensed nuclear chromosome	6.70e-05	6.55e-01	7.276	2	3	18
GO:0007067	mitotic nuclear division	1.58e-04	1.00e+00	4.665	3	8	165
GO:0043234	protein complex	3.22e-04	1.00e+00	4.317	3	8	210
GO:0031100	organ regeneration	4.11e-04	1.00e+00	5.987	2	2	44
GO:0004151	dihydroorotase activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:1903126	negative regulation of centriole-centriole cohesion	7.17e-04	1.00e+00	10.446	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0010265	SCF complex assembly	7.17e-04	1.00e+00	10.446	1	1	1
GO:0070335	aspartate binding	7.17e-04	1.00e+00	10.446	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	7.17e-04	1.00e+00	10.446	1	1	1
GO:0000278	mitotic cell cycle	1.05e-03	1.00e+00	3.736	3	35	314
GO:0016363	nuclear matrix	1.13e-03	1.00e+00	5.256	2	7	73
GO:0051299	centrosome separation	1.43e-03	1.00e+00	9.446	1	1	2
GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.43e-03	1.00e+00	9.446	1	1	2
GO:0046602	regulation of mitotic centrosome separation	1.43e-03	1.00e+00	9.446	1	2	2
GO:0006543	glutamine catabolic process	2.15e-03	1.00e+00	8.861	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.15e-03	1.00e+00	8.861	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.15e-03	1.00e+00	8.861	1	1	3
GO:0046777	protein autophosphorylation	2.37e-03	1.00e+00	4.718	2	2	106
GO:0051414	response to cortisol	2.86e-03	1.00e+00	8.446	1	1	4
GO:0031461	cullin-RING ubiquitin ligase complex	2.86e-03	1.00e+00	8.446	1	2	4
GO:0000212	meiotic spindle organization	2.86e-03	1.00e+00	8.446	1	1	4
GO:0006228	UTP biosynthetic process	2.86e-03	1.00e+00	8.446	1	1	4
GO:0001940	male pronucleus	2.86e-03	1.00e+00	8.446	1	1	4
GO:0004672	protein kinase activity	3.27e-03	1.00e+00	4.480	2	2	125
GO:0014075	response to amine	3.58e-03	1.00e+00	8.124	1	1	5
GO:0005827	polar microtubule	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000930	gamma-tubulin complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0001939	female pronucleus	3.58e-03	1.00e+00	8.124	1	1	5
GO:0046134	pyrimidine nucleoside biosynthetic process	4.29e-03	1.00e+00	7.861	1	1	6
GO:0031000	response to caffeine	4.29e-03	1.00e+00	7.861	1	1	6
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	5.01e-03	1.00e+00	7.639	1	2	7
GO:0010389	regulation of G2/M transition of mitotic cell cycle	5.01e-03	1.00e+00	7.639	1	1	7
GO:0033762	response to glucagon	5.01e-03	1.00e+00	7.639	1	1	7
GO:0000812	Swr1 complex	5.01e-03	1.00e+00	7.639	1	2	7
GO:0090307	spindle assembly involved in mitosis	5.72e-03	1.00e+00	7.446	1	2	8
GO:0031122	cytoplasmic microtubule organization	5.72e-03	1.00e+00	7.446	1	2	8
GO:0031011	Ino80 complex	5.72e-03	1.00e+00	7.446	1	2	8
GO:0016020	membrane	5.97e-03	1.00e+00	2.209	4	38	1207
GO:0005730	nucleolus	6.15e-03	1.00e+00	2.197	4	41	1217
GO:0008266	poly(U) RNA binding	6.44e-03	1.00e+00	7.276	1	1	9
GO:0005634	nucleus	6.74e-03	1.00e+00	1.367	6	67	3246
GO:0006541	glutamine metabolic process	7.15e-03	1.00e+00	7.124	1	1	10
GO:0043968	histone H2A acetylation	7.15e-03	1.00e+00	7.124	1	2	10
GO:0007020	microtubule nucleation	7.86e-03	1.00e+00	6.987	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	7.86e-03	1.00e+00	6.987	1	2	11
GO:0045120	pronucleus	7.86e-03	1.00e+00	6.987	1	1	11
GO:0035267	NuA4 histone acetyltransferase complex	8.57e-03	1.00e+00	6.861	1	3	12
GO:0007088	regulation of mitosis	8.57e-03	1.00e+00	6.861	1	1	12
GO:0017025	TBP-class protein binding	8.57e-03	1.00e+00	6.861	1	1	12
GO:0001824	blastocyst development	8.57e-03	1.00e+00	6.861	1	1	12
GO:0007095	mitotic G2 DNA damage checkpoint	9.28e-03	1.00e+00	6.746	1	1	13
GO:0005813	centrosome	9.59e-03	1.00e+00	3.684	2	8	217
GO:0043231	intracellular membrane-bounded organelle	9.68e-03	1.00e+00	3.678	2	7	218
GO:0051225	spindle assembly	1.14e-02	1.00e+00	6.446	1	1	16
GO:0006206	pyrimidine nucleobase metabolic process	1.21e-02	1.00e+00	6.359	1	2	17
GO:0000070	mitotic sister chromatid segregation	1.21e-02	1.00e+00	6.359	1	1	17
GO:0071364	cellular response to epidermal growth factor stimulus	1.28e-02	1.00e+00	6.276	1	1	18
GO:0003678	DNA helicase activity	1.28e-02	1.00e+00	6.276	1	3	18
GO:0071339	MLL1 complex	1.28e-02	1.00e+00	6.276	1	2	18
GO:0033574	response to testosterone	1.28e-02	1.00e+00	6.276	1	1	18
GO:0043044	ATP-dependent chromatin remodeling	1.43e-02	1.00e+00	6.124	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.43e-02	1.00e+00	6.124	1	2	20
GO:0051321	meiotic cell cycle	1.43e-02	1.00e+00	6.124	1	1	20
GO:0017144	drug metabolic process	1.50e-02	1.00e+00	6.054	1	1	21
GO:0043967	histone H4 acetylation	1.57e-02	1.00e+00	5.987	1	2	22
GO:0043392	negative regulation of DNA binding	1.64e-02	1.00e+00	5.922	1	1	23
GO:0045171	intercellular bridge	1.64e-02	1.00e+00	5.922	1	1	23
GO:0003730	mRNA 3'-UTR binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0031492	nucleosomal DNA binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0005737	cytoplasm	1.80e-02	1.00e+00	1.405	5	50	2633
GO:0070062	extracellular vesicular exosome	1.81e-02	1.00e+00	1.766	4	43	1641
GO:0005654	nucleoplasm	1.91e-02	1.00e+00	2.256	3	55	876
GO:0005524	ATP binding	2.01e-02	1.00e+00	2.230	3	23	892
GO:0018107	peptidyl-threonine phosphorylation	2.06e-02	1.00e+00	5.588	1	2	29
GO:0043195	terminal bouton	2.20e-02	1.00e+00	5.492	1	1	31
GO:0007595	lactation	2.27e-02	1.00e+00	5.446	1	2	32
GO:0042802	identical protein binding	2.44e-02	1.00e+00	2.978	2	7	354
GO:0005829	cytosol	2.45e-02	1.00e+00	1.643	4	58	1787
GO:0048146	positive regulation of fibroblast proliferation	2.48e-02	1.00e+00	5.317	1	1	35
GO:0005515	protein binding	2.53e-02	1.00e+00	1.021	6	76	4124
GO:0000226	microtubule cytoskeleton organization	2.55e-02	1.00e+00	5.276	1	2	36
GO:0040008	regulation of growth	2.62e-02	1.00e+00	5.237	1	2	37
GO:0035690	cellular response to drug	2.69e-02	1.00e+00	5.198	1	2	38
GO:0032508	DNA duplex unwinding	2.69e-02	1.00e+00	5.198	1	5	38
GO:0042995	cell projection	2.90e-02	1.00e+00	5.088	1	2	41
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	2.90e-02	1.00e+00	5.088	1	2	41
GO:0043086	negative regulation of catalytic activity	3.18e-02	1.00e+00	4.954	1	2	45
GO:0019903	protein phosphatase binding	3.32e-02	1.00e+00	4.891	1	3	47
GO:0000151	ubiquitin ligase complex	3.39e-02	1.00e+00	4.861	1	1	48
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.46e-02	1.00e+00	4.831	1	3	49
GO:0007059	chromosome segregation	3.53e-02	1.00e+00	4.802	1	2	50
GO:0006310	DNA recombination	3.53e-02	1.00e+00	4.802	1	6	50
GO:0006334	nucleosome assembly	3.60e-02	1.00e+00	4.774	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	3.60e-02	1.00e+00	4.774	1	5	51
GO:0000776	kinetochore	3.88e-02	1.00e+00	4.665	1	4	55
GO:0005681	spliceosomal complex	3.88e-02	1.00e+00	4.665	1	2	55
GO:0032355	response to estradiol	4.02e-02	1.00e+00	4.613	1	1	57
GO:0000777	condensed chromosome kinetochore	4.02e-02	1.00e+00	4.613	1	2	57
GO:0007265	Ras protein signal transduction	4.15e-02	1.00e+00	4.563	1	3	59
GO:0071013	catalytic step 2 spliceosome	4.29e-02	1.00e+00	4.515	1	5	61
GO:0007565	female pregnancy	4.50e-02	1.00e+00	4.446	1	2	64
GO:0000922	spindle pole	4.78e-02	1.00e+00	4.359	1	4	68
GO:0005200	structural constituent of cytoskeleton	4.78e-02	1.00e+00	4.359	1	2	68
GO:0006325	chromatin organization	4.91e-02	1.00e+00	4.317	1	3	70
GO:0001889	liver development	4.98e-02	1.00e+00	4.296	1	1	71
GO:0030496	midbody	5.12e-02	1.00e+00	4.256	1	1	73
GO:0001649	osteoblast differentiation	5.19e-02	1.00e+00	4.237	1	2	74
GO:0005815	microtubule organizing center	5.39e-02	1.00e+00	4.179	1	1	77
GO:0030529	ribonucleoprotein complex	5.73e-02	1.00e+00	4.088	1	4	82
GO:0016887	ATPase activity	6.95e-02	1.00e+00	3.802	1	6	100
GO:0007507	heart development	7.36e-02	1.00e+00	3.718	1	1	106
GO:0000790	nuclear chromatin	7.56e-02	1.00e+00	3.678	1	3	109
GO:0003924	GTPase activity	8.23e-02	1.00e+00	3.551	1	3	119
GO:0000398	mRNA splicing, via spliceosome	8.83e-02	1.00e+00	3.446	1	8	128
GO:0006184	GTP catabolic process	8.96e-02	1.00e+00	3.424	1	3	130
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.75e-02	1.00e+00	3.296	1	2	142
GO:0005874	microtubule	1.11e-01	1.00e+00	3.097	1	2	163
GO:0008380	RNA splicing	1.12e-01	1.00e+00	3.080	1	7	165
GO:0007283	spermatogenesis	1.14e-01	1.00e+00	3.054	1	2	168
GO:0043025	neuronal cell body	1.16e-01	1.00e+00	3.028	1	3	171
GO:0000166	nucleotide binding	1.20e-01	1.00e+00	2.987	1	6	176
GO:0016567	protein ubiquitination	1.27e-01	1.00e+00	2.891	1	3	188
GO:0004674	protein serine/threonine kinase activity	1.33e-01	1.00e+00	2.824	1	2	197
GO:0005525	GTP binding	1.33e-01	1.00e+00	2.824	1	5	197
GO:0030154	cell differentiation	1.37e-01	1.00e+00	2.774	1	3	204
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.37e-01	1.00e+00	2.781	1	1	203
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	19	203
GO:0019899	enzyme binding	1.41e-01	1.00e+00	2.732	1	4	210
GO:0019901	protein kinase binding	1.55e-01	1.00e+00	2.588	1	11	232
GO:0003723	RNA binding	1.64e-01	1.00e+00	2.498	1	11	247
GO:0006468	protein phosphorylation	1.97e-01	1.00e+00	2.212	1	1	301
GO:0045893	positive regulation of transcription, DNA-templated	2.41e-01	1.00e+00	1.888	1	10	377
GO:0005794	Golgi apparatus	2.62e-01	1.00e+00	1.749	1	5	415
GO:0010467	gene expression	3.26e-01	1.00e+00	1.383	1	31	535
GO:0008270	zinc ion binding	4.18e-01	1.00e+00	0.940	1	7	727
GO:0044822	poly(A) RNA binding	4.50e-01	1.00e+00	0.804	1	25	799
GO:0044281	small molecule metabolic process	4.69e-01	1.00e+00	0.725	1	32	844
GO:0046872	metal ion binding	5.05e-01	1.00e+00	0.579	1	10	934
GO:0006351	transcription, DNA-templated	5.58e-01	1.00e+00	0.375	1	9	1076

Wolf-ratios-Mammosphere-Adherent

reg-snw-4751

Statistics

Genes (7)

Interactions (6)

Related GO terms (142)