reg-snw-23481

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.876	1.41e-07	1.05e-03	2.23e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-23481 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
[ PES1 ]	23481	5	0.513	0.876	91	TF	Yes	-
CAD	790	25	0.807	0.973	67	-	-	-
EIF6	3692	3	0.700	0.876	49	-	Yes	-
RAN	5901	8	0.632	0.899	83	-	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	PES1	23481	pd	<>	reg.ITFP.txt: no annot
EIF6	3692	PES1	23481	pd	<	reg.ITFP.txt: no annot
CAD	790	PES1	23481	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
RAN	5901	PES1	23481	pd	<	reg.ITFP.txt: no annot

Related GO terms (153)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0042273	ribosomal large subunit biogenesis	2.42e-05	2.36e-01	7.987	2	3	11
GO:0016020	membrane	4.85e-04	1.00e+00	2.531	5	38	1207
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	5.10e-04	1.00e+00	5.831	2	3	49
GO:0004151	dihydroorotase activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0000054	ribosomal subunit export from nucleus	7.17e-04	1.00e+00	10.446	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0070335	aspartate binding	7.17e-04	1.00e+00	10.446	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	7.17e-04	1.00e+00	10.446	1	1	1
GO:0016363	nuclear matrix	1.13e-03	1.00e+00	5.256	2	7	73
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.43e-03	1.00e+00	9.446	1	1	2
GO:0042802	identical protein binding	1.48e-03	1.00e+00	3.563	3	7	354
GO:0005654	nucleoplasm	1.80e-03	1.00e+00	2.671	4	55	876
GO:0070062	extracellular vesicular exosome	2.07e-03	1.00e+00	2.088	5	43	1641
GO:0071733	transcriptional activation by promoter-enhancer looping	2.15e-03	1.00e+00	8.861	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	2.15e-03	1.00e+00	8.861	1	1	3
GO:0042256	mature ribosome assembly	2.15e-03	1.00e+00	8.861	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	2.15e-03	1.00e+00	8.861	1	1	3
GO:0006543	glutamine catabolic process	2.15e-03	1.00e+00	8.861	1	1	3
GO:0070545	PeBoW complex	2.15e-03	1.00e+00	8.861	1	1	3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.15e-03	1.00e+00	8.861	1	1	3
GO:0005638	lamin filament	2.15e-03	1.00e+00	8.861	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.15e-03	1.00e+00	8.861	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	2.15e-03	1.00e+00	8.861	1	1	3
GO:0030687	preribosome, large subunit precursor	2.15e-03	1.00e+00	8.861	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.15e-03	1.00e+00	8.861	1	1	3
GO:0051414	response to cortisol	2.86e-03	1.00e+00	8.446	1	1	4
GO:0000212	meiotic spindle organization	2.86e-03	1.00e+00	8.446	1	1	4
GO:0071169	establishment of protein localization to chromatin	2.86e-03	1.00e+00	8.446	1	1	4
GO:0006228	UTP biosynthetic process	2.86e-03	1.00e+00	8.446	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	2.86e-03	1.00e+00	8.446	1	1	4
GO:0007000	nucleolus organization	2.86e-03	1.00e+00	8.446	1	1	4
GO:0003924	GTPase activity	2.97e-03	1.00e+00	4.551	2	3	119
GO:0006184	GTP catabolic process	3.54e-03	1.00e+00	4.424	2	3	130
GO:0014075	response to amine	3.58e-03	1.00e+00	8.124	1	1	5
GO:0005827	polar microtubule	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000930	gamma-tubulin complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0043023	ribosomal large subunit binding	3.58e-03	1.00e+00	8.124	1	2	5
GO:0046134	pyrimidine nucleoside biosynthetic process	4.29e-03	1.00e+00	7.861	1	1	6
GO:0031000	response to caffeine	4.29e-03	1.00e+00	7.861	1	1	6
GO:0075733	intracellular transport of virus	5.01e-03	1.00e+00	7.639	1	1	7
GO:0000812	Swr1 complex	5.01e-03	1.00e+00	7.639	1	2	7
GO:0031122	cytoplasmic microtubule organization	5.72e-03	1.00e+00	7.446	1	2	8
GO:0031011	Ino80 complex	5.72e-03	1.00e+00	7.446	1	2	8
GO:0005730	nucleolus	6.15e-03	1.00e+00	2.197	4	41	1217
GO:0008266	poly(U) RNA binding	6.44e-03	1.00e+00	7.276	1	1	9
GO:0006541	glutamine metabolic process	7.15e-03	1.00e+00	7.124	1	1	10
GO:0043968	histone H2A acetylation	7.15e-03	1.00e+00	7.124	1	2	10
GO:0033365	protein localization to organelle	7.86e-03	1.00e+00	6.987	1	1	11
GO:0007020	microtubule nucleation	7.86e-03	1.00e+00	6.987	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	7.86e-03	1.00e+00	6.987	1	2	11
GO:0045120	pronucleus	7.86e-03	1.00e+00	6.987	1	1	11
GO:0005525	GTP binding	7.95e-03	1.00e+00	3.824	2	5	197
GO:0035267	NuA4 histone acetyltransferase complex	8.57e-03	1.00e+00	6.861	1	3	12
GO:0043234	protein complex	9.00e-03	1.00e+00	3.732	2	8	210
GO:0071392	cellular response to estradiol stimulus	9.28e-03	1.00e+00	6.746	1	1	13
GO:0035066	positive regulation of histone acetylation	9.28e-03	1.00e+00	6.746	1	1	13
GO:0006259	DNA metabolic process	1.00e-02	1.00e+00	6.639	1	3	14
GO:0005719	nuclear euchromatin	1.14e-02	1.00e+00	6.446	1	1	16
GO:0000793	condensed chromosome	1.14e-02	1.00e+00	6.446	1	1	16
GO:0006206	pyrimidine nucleobase metabolic process	1.21e-02	1.00e+00	6.359	1	2	17
GO:0043021	ribonucleoprotein complex binding	1.21e-02	1.00e+00	6.359	1	1	17
GO:0043022	ribosome binding	1.21e-02	1.00e+00	6.359	1	1	17
GO:0007052	mitotic spindle organization	1.21e-02	1.00e+00	6.359	1	2	17
GO:0006611	protein export from nucleus	1.28e-02	1.00e+00	6.276	1	2	18
GO:0071364	cellular response to epidermal growth factor stimulus	1.28e-02	1.00e+00	6.276	1	1	18
GO:0003678	DNA helicase activity	1.28e-02	1.00e+00	6.276	1	3	18
GO:0071339	MLL1 complex	1.28e-02	1.00e+00	6.276	1	2	18
GO:0033574	response to testosterone	1.28e-02	1.00e+00	6.276	1	1	18
GO:0000794	condensed nuclear chromosome	1.28e-02	1.00e+00	6.276	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.43e-02	1.00e+00	6.124	1	2	20
GO:0044822	poly(A) RNA binding	1.49e-02	1.00e+00	2.389	3	25	799
GO:0017144	drug metabolic process	1.50e-02	1.00e+00	6.054	1	1	21
GO:0043967	histone H4 acetylation	1.57e-02	1.00e+00	5.987	1	2	22
GO:0007286	spermatid development	1.64e-02	1.00e+00	5.922	1	1	23
GO:0004003	ATP-dependent DNA helicase activity	1.78e-02	1.00e+00	5.802	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0031492	nucleosomal DNA binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0005737	cytoplasm	1.80e-02	1.00e+00	1.405	5	50	2633
GO:0034644	cellular response to UV	1.99e-02	1.00e+00	5.639	1	2	28
GO:0018107	peptidyl-threonine phosphorylation	2.06e-02	1.00e+00	5.588	1	2	29
GO:0050681	androgen receptor binding	2.13e-02	1.00e+00	5.539	1	2	30
GO:0043195	terminal bouton	2.20e-02	1.00e+00	5.492	1	1	31
GO:0031490	chromatin DNA binding	2.20e-02	1.00e+00	5.492	1	1	31
GO:0007595	lactation	2.27e-02	1.00e+00	5.446	1	2	32
GO:0019003	GDP binding	2.41e-02	1.00e+00	5.359	1	1	34
GO:0032092	positive regulation of protein binding	2.41e-02	1.00e+00	5.359	1	1	34
GO:0005829	cytosol	2.45e-02	1.00e+00	1.643	4	58	1787
GO:0030521	androgen receptor signaling pathway	2.48e-02	1.00e+00	5.317	1	2	35
GO:0005515	protein binding	2.53e-02	1.00e+00	1.021	6	76	4124
GO:0000226	microtubule cytoskeleton organization	2.55e-02	1.00e+00	5.276	1	2	36
GO:0003743	translation initiation factor activity	2.62e-02	1.00e+00	5.237	1	2	37
GO:0040008	regulation of growth	2.62e-02	1.00e+00	5.237	1	2	37
GO:0035690	cellular response to drug	2.69e-02	1.00e+00	5.198	1	2	38
GO:0032508	DNA duplex unwinding	2.69e-02	1.00e+00	5.198	1	5	38
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2.83e-02	1.00e+00	5.124	1	2	40
GO:0042995	cell projection	2.90e-02	1.00e+00	5.088	1	2	41
GO:0003684	damaged DNA binding	2.90e-02	1.00e+00	5.088	1	9	41
GO:0031100	organ regeneration	3.11e-02	1.00e+00	4.987	1	2	44
GO:0006310	DNA recombination	3.53e-02	1.00e+00	4.802	1	6	50
GO:0005643	nuclear pore	3.60e-02	1.00e+00	4.774	1	2	51
GO:0055086	nucleobase-containing small molecule metabolic process	3.60e-02	1.00e+00	4.774	1	5	51
GO:0006338	chromatin remodeling	3.88e-02	1.00e+00	4.665	1	2	55
GO:0005681	spliceosomal complex	3.88e-02	1.00e+00	4.665	1	2	55
GO:0000785	chromatin	4.15e-02	1.00e+00	4.563	1	5	59
GO:0071013	catalytic step 2 spliceosome	4.29e-02	1.00e+00	4.515	1	5	61
GO:0005634	nucleus	4.47e-02	1.00e+00	1.104	5	67	3246
GO:0007565	female pregnancy	4.50e-02	1.00e+00	4.446	1	2	64
GO:0042470	melanosome	4.50e-02	1.00e+00	4.446	1	2	64
GO:0006364	rRNA processing	4.71e-02	1.00e+00	4.380	1	4	67
GO:0005200	structural constituent of cytoskeleton	4.78e-02	1.00e+00	4.359	1	2	68
GO:0051082	unfolded protein binding	4.91e-02	1.00e+00	4.317	1	4	70
GO:0006325	chromatin organization	4.91e-02	1.00e+00	4.317	1	3	70
GO:0001889	liver development	4.98e-02	1.00e+00	4.296	1	1	71
GO:0051726	regulation of cell cycle	5.12e-02	1.00e+00	4.256	1	2	73
GO:0001649	osteoblast differentiation	5.19e-02	1.00e+00	4.237	1	2	74
GO:0010467	gene expression	5.24e-02	1.00e+00	2.383	2	31	535
GO:0019058	viral life cycle	5.46e-02	1.00e+00	4.161	1	3	78
GO:0030529	ribonucleoprotein complex	5.73e-02	1.00e+00	4.088	1	4	82
GO:0000086	G2/M transition of mitotic cell cycle	6.75e-02	1.00e+00	3.846	1	5	97
GO:0006457	protein folding	6.75e-02	1.00e+00	3.846	1	4	97
GO:0006413	translational initiation	6.89e-02	1.00e+00	3.817	1	4	99
GO:0016887	ATPase activity	6.95e-02	1.00e+00	3.802	1	6	100
GO:0007507	heart development	7.36e-02	1.00e+00	3.718	1	1	106
GO:0046777	protein autophosphorylation	7.36e-02	1.00e+00	3.718	1	2	106
GO:0000790	nuclear chromatin	7.56e-02	1.00e+00	3.678	1	3	109
GO:0004672	protein kinase activity	8.63e-02	1.00e+00	3.480	1	2	125
GO:0000398	mRNA splicing, via spliceosome	8.83e-02	1.00e+00	3.446	1	8	128
GO:0019904	protein domain specific binding	8.96e-02	1.00e+00	3.424	1	2	130
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.75e-02	1.00e+00	3.296	1	2	142
GO:0005622	intracellular	9.95e-02	1.00e+00	3.266	1	1	145
GO:0008380	RNA splicing	1.12e-01	1.00e+00	3.080	1	7	165
GO:0007067	mitotic nuclear division	1.12e-01	1.00e+00	3.080	1	8	165
GO:0043025	neuronal cell body	1.16e-01	1.00e+00	3.028	1	3	171
GO:0044281	small molecule metabolic process	1.17e-01	1.00e+00	1.725	2	32	844
GO:0007264	small GTPase mediated signal transduction	1.18e-01	1.00e+00	3.003	1	1	174
GO:0000166	nucleotide binding	1.20e-01	1.00e+00	2.987	1	6	176
GO:0003713	transcription coactivator activity	1.25e-01	1.00e+00	2.922	1	5	184
GO:0005524	ATP binding	1.29e-01	1.00e+00	1.645	2	23	892
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	19	203
GO:0019899	enzyme binding	1.41e-01	1.00e+00	2.732	1	4	210
GO:0005813	centrosome	1.46e-01	1.00e+00	2.684	1	8	217
GO:0006200	ATP catabolic process	1.47e-01	1.00e+00	2.671	1	8	219
GO:0008283	cell proliferation	1.59e-01	1.00e+00	2.545	1	6	239
GO:0003723	RNA binding	1.64e-01	1.00e+00	2.498	1	11	247
GO:0003682	chromatin binding	1.67e-01	1.00e+00	2.469	1	6	252
GO:0000278	mitotic cell cycle	2.05e-01	1.00e+00	2.151	1	35	314
GO:0045893	positive regulation of transcription, DNA-templated	2.41e-01	1.00e+00	1.888	1	10	377
GO:0016032	viral process	2.69e-01	1.00e+00	1.705	1	32	428
GO:0007165	signal transduction	3.67e-01	1.00e+00	1.175	1	5	618
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.115	1	8	644
GO:0008270	zinc ion binding	4.18e-01	1.00e+00	0.940	1	7	727
GO:0006351	transcription, DNA-templated	5.58e-01	1.00e+00	0.375	1	9	1076

Wolf-ratios-Mammosphere-Adherent

reg-snw-23481

Statistics

Genes (7)

Interactions (7)

Related GO terms (153)