reg-snw-8394

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 4.751 5.99e-25 4.27e-04 7.04e-04
tai-screen-luciferase-reg-snw-8394 subnetwork

Genes (5)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree Transcription factor List-Gonzales GI Tai-Hits
ZMAT1 84460 1-3.1824.75136TF--
MRPS12 6183 13-5.4215.516307TFYes-
[ PIP5K1A ] 8394 1-1.8204.75130---
COPA 1314 25-9.3955.672170TFYesYes
PSMD3 5709 3-3.9354.90355TF-Yes

Interactions (4)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
COPA 1314 PIP5K1A 8394 pd > reg.ITFP.txt: no annot
PSMD3 5709 PIP5K1A 8394 pd > reg.ITFP.txt: no annot
PSMD3 5709 MRPS12 6183 pd <> reg.ITFP.txt: no annot
PIP5K1A 8394 ZMAT1 84460 pd < reg.ITFP.txt: no annot

Related GO terms (75)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006650glycerophospholipid metabolic process5.12e-041.00e+0010.931111
GO:0030157pancreatic juice secretion2.05e-031.00e+008.931114
GO:00163081-phosphatidylinositol-4-phosphate 5-kinase activity2.05e-031.00e+008.931114
GO:0097178ruffle assembly2.56e-031.00e+008.610115
GO:0030126COPI vesicle coat3.58e-031.00e+008.124117
GO:0010761fibroblast migration4.09e-031.00e+007.931118
GO:0032863activation of Rac GTPase activity4.09e-031.00e+007.931118
GO:0005847mRNA cleavage and polyadenylation specificity factor complex4.60e-031.00e+007.762119
GO:0008654phospholipid biosynthetic process5.11e-031.00e+007.6101110
GO:0072661protein targeting to plasma membrane5.11e-031.00e+007.6101110
GO:0005838proteasome regulatory particle5.11e-031.00e+007.6101210
GO:0030234enzyme regulator activity5.62e-031.00e+007.4721111
GO:0015935small ribosomal subunit6.13e-031.00e+007.3471412
GO:0048205COPI coating of Golgi vesicle6.13e-031.00e+007.3471112
GO:0022624proteasome accessory complex7.15e-031.00e+007.1241214
GO:0042176regulation of protein catabolic process7.15e-031.00e+007.1241314
GO:0046854phosphatidylinositol phosphorylation7.66e-031.00e+007.0251115
GO:0006890retrograde vesicle-mediated transport, Golgi to ER8.68e-031.00e+006.8441117
GO:0048041focal adhesion assembly9.69e-031.00e+006.6841119
GO:0005761mitochondrial ribosome1.02e-021.00e+006.6101120
GO:0006909phagocytosis1.12e-021.00e+006.4721122
GO:0031532actin cytoskeleton reorganization1.58e-021.00e+005.9771231
GO:0060326cell chemotaxis1.58e-021.00e+005.9771131
GO:0019900kinase binding1.63e-021.00e+005.9311232
GO:0006661phosphatidylinositol biosynthetic process1.78e-021.00e+005.8021135
GO:0030216keratinocyte differentiation1.93e-021.00e+005.6841138
GO:0006521regulation of cellular amino acid metabolic process2.08e-021.00e+005.5741341
GO:0000502proteasome complex2.38e-021.00e+005.3771247
GO:0032587ruffle membrane2.53e-021.00e+005.2881150
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.63e-021.00e+005.2311352
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.69e-021.00e+005.2041353
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.84e-021.00e+005.1241356
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.89e-021.00e+005.0991357
GO:0005179hormone activity3.04e-021.00e+005.0251160
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.04e-021.00e+005.0251360
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.09e-021.00e+005.0011361
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.28e-021.00e+004.9091365
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.53e-021.00e+004.8021470
GO:0030027lamellipodium4.43e-021.00e+004.4721388
GO:0006886intracellular protein transport4.48e-021.00e+004.4561189
GO:0061024membrane organization4.48e-021.00e+004.4561389
GO:0006644phospholipid metabolic process4.48e-021.00e+004.4561189
GO:0005829cytosol4.57e-021.00e+001.7133331787
GO:0000209protein polyubiquitination4.62e-021.00e+004.4081392
GO:0016477cell migration4.82e-021.00e+004.3471196
GO:0005198structural molecule activity5.07e-021.00e+004.27311101
GO:0034641cellular nitrogen compound metabolic process5.26e-021.00e+004.21713105
GO:0003735structural constituent of ribosome5.46e-021.00e+004.16318109
GO:0042981regulation of apoptotic process5.61e-021.00e+004.12414112
GO:0016607nuclear speck6.09e-021.00e+004.00112122
GO:0000082G1/S transition of mitotic cell cycle6.24e-021.00e+003.96616125
GO:0044281small molecule metabolic process6.26e-021.00e+002.21028844
GO:0016071mRNA metabolic process8.41e-021.00e+003.522111170
GO:0006412translation8.79e-021.00e+003.456113178
GO:0016070RNA metabolic process9.26e-021.00e+003.377111188
GO:0016020membrane1.18e-011.00e+001.6942251207
GO:0005730nucleolus1.20e-011.00e+001.6822211217
GO:0005737cytoplasm1.25e-011.00e+001.1543392633
GO:0005925focal adhesion1.36e-011.00e+002.792112282
GO:0000278mitotic cell cycle1.51e-011.00e+002.63719314
GO:0043066negative regulation of apoptotic process1.54e-011.00e+002.60116322
GO:0006915apoptotic process1.93e-011.00e+002.24814411
GO:0070062extracellular vesicular exosome1.99e-011.00e+001.2512281641
GO:0016032viral process2.01e-011.00e+002.190113428
GO:0005634nucleus2.08e-011.00e+000.8523403246
GO:0010467gene expression2.46e-011.00e+001.868117535
GO:0007165signal transduction2.79e-011.00e+001.66015618
GO:0005615extracellular space2.92e-011.00e+001.58512651
GO:0008270zinc ion binding3.21e-011.00e+001.42615727
GO:0044822poly(A) RNA binding3.47e-011.00e+001.289125799
GO:0005654nucleoplasm3.75e-011.00e+001.157116876
GO:0005524ATP binding3.81e-011.00e+001.131110892
GO:0003677DNA binding4.00e-011.00e+001.044112947
GO:0005886plasma membrane6.35e-011.00e+000.1311131784
GO:0005515protein binding7.01e-011.00e+00-0.0782504124