int-snw-80895

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	6.968	7.69e-168	5.21e-09	3.96e-04

tai-screen-luciferase-int-snw-80895 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
COPZ1	22818	32	-8.301	9.063	13	Yes	Yes
COPA	1314	32	-9.395	9.063	170	Yes	Yes
ILK	3611	2	2.764	6.968	91	-	-
ARCN1	372	32	-8.232	9.063	118	Yes	Yes
[ ILKAP ]	80895	1	2.382	6.968	8	-	-
COPB2	9276	32	-13.168	9.063	41	Yes	Yes
COPB1	1315	22	-6.221	9.063	118	Yes	Yes
COPG1	22820	9	-5.279	7.138	37	Yes	Yes

Interactions (16)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
ILK	3611	ILKAP	80895	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, HPRD; int.HPRD: in vivo, yeast 2-hybrid
ARCN1	372	COPB1	1315	pp	--	int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
ILK	3611	COPB2	9276	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid
COPB1	1315	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association)
COPA	1314	COPB1	1315	pp	--	int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
ARCN1	372	COPG1	22820	pp	--	int.I2D: HPRD; int.HPRD: in vivo
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
ILK	3611	COPG1	22820	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
COPB1	1315	COPG1	22820	pp	--	int.I2D: BioGrid, HPRD; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
COPB2	9276	COPG1	22820	pp	--	int.I2D: BioGrid
COPZ1	22818	COPG1	22820	pp	--	int.I2D: BioGrid, HPRD, BIND; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
COPB1	1315	COPB2	9276	pp	--	int.I2D: BioGrid

Related GO terms (93)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0030126	COPI vesicle coat	2.07e-18	2.99e-14	9.816	6	7	12
GO:0048205	COPI coating of Golgi vesicle	3.84e-18	5.54e-14	9.701	6	8	13
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.96e-16	5.71e-12	8.757	6	8	25
GO:0061024	membrane organization	2.56e-11	3.70e-07	6.221	6	12	145
GO:0006886	intracellular protein transport	6.99e-11	1.01e-06	5.983	6	7	171
GO:0006891	intra-Golgi vesicle-mediated transport	7.59e-08	1.09e-03	8.314	3	4	17
GO:0005198	structural molecule activity	7.62e-07	1.10e-02	5.587	4	6	150
GO:0005829	cytosol	3.14e-05	4.52e-01	2.338	7	61	2496
GO:0021691	cerebellar Purkinje cell layer maturation	5.55e-04	1.00e+00	10.816	1	1	1
GO:0051683	establishment of Golgi localization	1.66e-03	1.00e+00	9.231	1	2	3
GO:0033262	regulation of nuclear cell cycle DNA replication	1.66e-03	1.00e+00	9.231	1	1	3
GO:0072384	organelle transport along microtubule	2.22e-03	1.00e+00	8.816	1	2	4
GO:0032288	myelin assembly	3.32e-03	1.00e+00	8.231	1	1	6
GO:0010761	fibroblast migration	3.88e-03	1.00e+00	8.009	1	1	7
GO:0030157	pancreatic juice secretion	3.88e-03	1.00e+00	8.009	1	1	7
GO:2000178	negative regulation of neural precursor cell proliferation	4.43e-03	1.00e+00	7.816	1	1	8
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	4.43e-03	1.00e+00	7.816	1	1	8
GO:0043206	extracellular fibril organization	4.98e-03	1.00e+00	7.646	1	1	9
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	5.53e-03	1.00e+00	7.494	1	1	10
GO:0005798	Golgi-associated vesicle	5.53e-03	1.00e+00	7.494	1	1	10
GO:0045663	positive regulation of myoblast differentiation	6.09e-03	1.00e+00	7.357	1	1	11
GO:0014912	negative regulation of smooth muscle cell migration	6.09e-03	1.00e+00	7.357	1	1	11
GO:0021675	nerve development	6.64e-03	1.00e+00	7.231	1	1	12
GO:0022011	myelination in peripheral nervous system	6.64e-03	1.00e+00	7.231	1	1	12
GO:0030131	clathrin adaptor complex	7.74e-03	1.00e+00	7.009	1	2	14
GO:0050775	positive regulation of dendrite morphogenesis	8.29e-03	1.00e+00	6.909	1	1	15
GO:0016020	membrane	8.74e-03	1.00e+00	2.101	4	41	1681
GO:0045773	positive regulation of axon extension	9.94e-03	1.00e+00	6.646	1	1	18
GO:0043034	costamere	1.10e-02	1.00e+00	6.494	1	2	20
GO:0043473	pigmentation	1.10e-02	1.00e+00	6.494	1	1	20
GO:0001954	positive regulation of cell-matrix adhesion	1.16e-02	1.00e+00	6.424	1	1	21
GO:0043231	intracellular membrane-bounded organelle	1.24e-02	1.00e+00	3.503	2	5	318
GO:0042327	positive regulation of phosphorylation	1.38e-02	1.00e+00	6.172	1	1	25
GO:0007569	cell aging	1.38e-02	1.00e+00	6.172	1	1	25
GO:0030513	positive regulation of BMP signaling pathway	1.43e-02	1.00e+00	6.116	1	1	26
GO:0048662	negative regulation of smooth muscle cell proliferation	1.54e-02	1.00e+00	6.009	1	1	28
GO:0000139	Golgi membrane	1.58e-02	1.00e+00	3.320	2	6	361
GO:0043198	dendritic shaft	1.60e-02	1.00e+00	5.958	1	1	29
GO:0032956	regulation of actin cytoskeleton organization	1.65e-02	1.00e+00	5.909	1	2	30
GO:0048812	neuron projection morphogenesis	1.71e-02	1.00e+00	5.862	1	2	31
GO:0043491	protein kinase B signaling	1.76e-02	1.00e+00	5.816	1	1	32
GO:0030017	sarcomere	1.87e-02	1.00e+00	5.729	1	2	34
GO:0034446	substrate adhesion-dependent cell spreading	1.98e-02	1.00e+00	5.646	1	1	36
GO:0070527	platelet aggregation	2.09e-02	1.00e+00	5.568	1	1	38
GO:0043195	terminal bouton	2.25e-02	1.00e+00	5.459	1	1	41
GO:0004722	protein serine/threonine phosphatase activity	2.31e-02	1.00e+00	5.424	1	1	42
GO:0001658	branching involved in ureteric bud morphogenesis	2.36e-02	1.00e+00	5.390	1	1	43
GO:0008344	adult locomotory behavior	2.42e-02	1.00e+00	5.357	1	1	44
GO:0043406	positive regulation of MAP kinase activity	2.52e-02	1.00e+00	5.293	1	2	46
GO:0090263	positive regulation of canonical Wnt signaling pathway	2.63e-02	1.00e+00	5.231	1	2	48
GO:0045669	positive regulation of osteoblast differentiation	3.01e-02	1.00e+00	5.035	1	1	55
GO:0001725	stress fiber	3.01e-02	1.00e+00	5.035	1	1	55
GO:0051291	protein heterooligomerization	3.06e-02	1.00e+00	5.009	1	1	56
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	3.06e-02	1.00e+00	5.009	1	1	56
GO:0005737	cytoplasm	3.28e-02	1.00e+00	1.259	5	43	3767
GO:0006469	negative regulation of protein kinase activity	3.55e-02	1.00e+00	4.794	1	1	65
GO:0034329	cell junction assembly	3.71e-02	1.00e+00	4.729	1	1	68
GO:0018105	peptidyl-serine phosphorylation	3.76e-02	1.00e+00	4.708	1	4	69
GO:0051897	positive regulation of protein kinase B signaling	3.82e-02	1.00e+00	4.687	1	2	70
GO:0005794	Golgi apparatus	4.22e-02	1.00e+00	2.563	2	9	610
GO:0007229	integrin-mediated signaling pathway	4.25e-02	1.00e+00	4.531	1	3	78
GO:0005179	hormone activity	4.30e-02	1.00e+00	4.512	1	1	79
GO:0007160	cell-matrix adhesion	4.46e-02	1.00e+00	4.459	1	1	82
GO:0005178	integrin binding	5.20e-02	1.00e+00	4.231	1	2	96
GO:0006470	protein dephosphorylation	5.31e-02	1.00e+00	4.201	1	1	98
GO:0017124	SH3 domain binding	6.10e-02	1.00e+00	3.996	1	1	113
GO:0043524	negative regulation of neuron apoptotic process	6.31e-02	1.00e+00	3.946	1	2	117
GO:0007050	cell cycle arrest	6.68e-02	1.00e+00	3.862	1	1	124
GO:0030027	lamellipodium	6.73e-02	1.00e+00	3.850	1	2	125
GO:0030335	positive regulation of cell migration	6.83e-02	1.00e+00	3.827	1	2	127
GO:0005911	cell-cell junction	7.30e-02	1.00e+00	3.729	1	2	136
GO:0004871	signal transducer activity	1.10e-01	1.00e+00	3.116	1	2	208
GO:0043025	neuronal cell body	1.28e-01	1.00e+00	2.879	1	4	245
GO:0043234	protein complex	1.52e-01	1.00e+00	2.612	1	6	295
GO:0004674	protein serine/threonine kinase activity	1.59e-01	1.00e+00	2.549	1	5	308
GO:0019901	protein kinase binding	1.63e-01	1.00e+00	2.508	1	6	317
GO:0008283	cell proliferation	1.68e-01	1.00e+00	2.459	1	4	328
GO:0030054	cell junction	1.72e-01	1.00e+00	2.424	1	4	336
GO:0005925	focal adhesion	1.86e-01	1.00e+00	2.300	1	19	366
GO:0008284	positive regulation of cell proliferation	1.93e-01	1.00e+00	2.239	1	7	382
GO:0006468	protein phosphorylation	2.28e-01	1.00e+00	1.971	1	6	460
GO:0045893	positive regulation of transcription, DNA-templated	2.36e-01	1.00e+00	1.915	1	5	478
GO:0016032	viral process	2.61e-01	1.00e+00	1.755	1	33	534
GO:0005783	endoplasmic reticulum	2.70e-01	1.00e+00	1.697	1	3	556
GO:0005615	extracellular space	4.23e-01	1.00e+00	0.914	1	2	957
GO:0005886	plasma membrane	4.34e-01	1.00e+00	0.482	2	20	2582
GO:0005515	protein binding	4.47e-01	1.00e+00	0.260	4	62	6024
GO:0044822	poly(A) RNA binding	4.56e-01	1.00e+00	0.772	1	32	1056
GO:0005524	ATP binding	5.30e-01	1.00e+00	0.474	1	15	1298
GO:0046872	metal ion binding	5.32e-01	1.00e+00	0.464	1	10	1307
GO:0005730	nucleolus	6.20e-01	1.00e+00	0.136	1	24	1641
GO:0070062	extracellular vesicular exosome	7.67e-01	1.00e+00	-0.413	1	40	2400
GO:0005634	nucleus	9.52e-01	1.00e+00	-1.338	1	43	4559

Tai-Luciferase

int-snw-80895

Statistics

Genes (8)

Interactions (16)

Related GO terms (93)