int-snw-7133

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 6.428 5.80e-139 2.51e-07 2.21e-03
tai-screen-luciferase-int-snw-7133 subnetwork

Genes (25)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS8 6202 10-5.5457.555234--
CHMP2A 27243 10-9.0377.55541YesYes
RPS15 6209 7-5.0407.011116Yes-
COPA 1314 32-9.3959.063170YesYes
RPS24 6229 21-7.0348.389217Yes-
VIM 7431 2-3.7606.428246--
RPS9 6203 18-7.1277.555140Yes-
COPB2 9276 32-13.1689.06341YesYes
[ TNFRSF1B ] 7133 1-3.3196.428109--
RPS4X 6191 18-6.7477.555263Yes-
COPZ1 22818 32-8.3019.06313YesYes
RPS16 6217 5-5.4447.011202--
RPS15A 6210 8-5.4137.555177Yes-
CDC42 998 11-6.9608.389265YesYes
RPS27A 6233 15-5.6318.389342Yes-
RPS14 6208 4-4.8037.011191Yes-
RPS11 6205 17-6.5887.555175Yes-
RPS6 6194 17-5.6038.046208Yes-
RPS18 6222 1-3.7096.428169Yes-
UBB 7314 3-4.2896.428147--
RPS26 6231 17-7.4788.04660Yes-
ARCN1 372 32-8.2329.063118YesYes
COPG1 22820 9-5.2797.13837YesYes
COPB1 1315 22-6.2219.063118YesYes
RPS13 6207 17-6.5897.555174Yes-

Interactions (89)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RPS8 6202 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS18 6222 TNFRSF1B 7133 pp -- int.Intact: MI:0915(physical association);
int.I2D: MINT, IntAct;
int.Mint: MI:0915(physical association)
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS16 6217 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS27A 6233 UBB 7314 pp -- int.I2D: BIND
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
ARCN1 372 COPG1 22820 pp -- int.I2D: HPRD;
int.HPRD: in vivo
RPS4X 6191 RPS18 6222 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS18 6222 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
TNFRSF1B 7133 UBB 7314 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS15 6209 RPS15A 6210 pp -- int.I2D: YeastMedium, INTEROLOG
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
RPS18 6222 RPS27A 6233 pp -- int.I2D: YeastLow
RPS13 6207 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS18 6222 pp -- int.I2D: YeastMedium, BioGrid_Yeast
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS11 6205 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS6 6194 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 TNFRSF1B 7133 pp -- int.Intact: MI:0915(physical association);
int.I2D: MINT, IntAct;
int.Mint: MI:0915(physical association)
RPS15A 6210 RPS18 6222 pp -- int.I2D: YeastLow
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS14 6208 RPS18 6222 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
CDC42 998 UBB 7314 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
COPB1 1315 COPG1 22820 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
RPS14 6208 TNFRSF1B 7133 pp -- int.Intact: MI:0915(physical association);
int.I2D: MINT, IntAct;
int.Mint: MI:0915(physical association)
RPS6 6194 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
COPB1 1315 TNFRSF1B 7133 pp -- int.Intact: MI:0915(physical association);
int.I2D: MINT, IntAct;
int.Mint: MI:0915(physical association)
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
COPB2 9276 COPG1 22820 pp -- int.I2D: BioGrid
RPS15 6209 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
TNFRSF1B 7133 VIM 7431 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
COPZ1 22818 COPG1 22820 pp -- int.I2D: BioGrid, HPRD, BIND;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RPS8 6202 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS18 6222 pp -- int.I2D: INTEROLOG, YeastMedium, Yu_GoldStd
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS18 6222 pp -- int.I2D: IntAct
RPS14 6208 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
RPS6 6194 RPS18 6222 pp -- int.I2D: YeastLow
RPS4X 6191 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS18 6222 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)

Related GO terms (292)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit3.44e-314.96e-277.694142039
GO:0019058viral life cycle1.74e-282.51e-246.3271623115
GO:0019083viral transcription4.03e-265.82e-226.640142081
GO:0006415translational termination1.19e-251.72e-216.537142087
GO:0006414translational elongation3.25e-254.69e-216.440142093
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.73e-242.49e-206.2791420104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay6.75e-249.74e-206.1471420114
GO:0006413translational initiation5.22e-237.53e-195.9461421131
GO:0003735structural constituent of ribosome1.01e-221.45e-185.8821422137
GO:0016071mRNA metabolic process1.22e-211.77e-175.2781525223
GO:0016032viral process4.88e-217.04e-174.2811833534
GO:0016070RNA metabolic process5.86e-218.45e-175.1311525247
GO:0006412translation1.76e-192.54e-155.1341423230
GO:0005829cytosol9.92e-181.43e-132.47224612496
GO:0015935small ribosomal subunit3.59e-165.18e-127.8927917
GO:0044267cellular protein metabolic process4.54e-156.55e-114.0911423474
GO:0030126COPI vesicle coat1.30e-141.88e-108.1726712
GO:0010467gene expression1.80e-142.60e-103.6931529669
GO:0048205COPI coating of Golgi vesicle2.41e-143.48e-108.0576813
GO:0016020membrane1.48e-132.14e-092.70519411681
GO:0061024membrane organization1.46e-122.10e-085.162912145
GO:0006890retrograde vesicle-mediated transport, Golgi to ER2.46e-123.54e-087.1136825
GO:0005925focal adhesion7.85e-121.13e-074.1161119366
GO:0044822poly(A) RNA binding1.38e-111.99e-073.03515321056
GO:0042274ribosomal small subunit biogenesis3.44e-094.96e-057.5874612
GO:0005840ribosome4.41e-086.35e-045.6365858
GO:0019843rRNA binding1.20e-071.73e-036.4174427
GO:0070062extracellular vesicular exosome1.48e-072.14e-031.94316402400
GO:0006886intracellular protein transport3.74e-075.39e-034.33967171
GO:0006891intra-Golgi vesicle-mediated transport3.08e-064.44e-026.6703417
GO:0036464cytoplasmic ribonucleoprotein granule6.93e-061.00e-016.2983322
GO:0051683establishment of Golgi localization8.64e-061.25e-018.587223
GO:0072384organelle transport along microtubule1.73e-052.49e-018.172224
GO:0006364rRNA processing1.93e-052.78e-014.6184794
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.88e-054.15e-017.850235
GO:0033119negative regulation of RNA splicing2.88e-054.15e-017.850225
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway3.16e-054.56e-015.5873336
GO:0030529ribonucleoprotein complex3.84e-055.54e-014.36547112
GO:0045182translation regulator activity4.31e-056.21e-017.587226
GO:0000028ribosomal small subunit assembly6.03e-058.69e-017.365237
GO:0005198structural molecule activity1.20e-041.00e+003.94346150
GO:0016197endosomal transport1.27e-041.00e+004.9243357
GO:0019082viral protein processing1.88e-041.00e+006.5872212
GO:0032479regulation of type I interferon production2.22e-041.00e+006.4722213
GO:0075733intracellular transport of virus3.86e-041.00e+006.0852317
GO:0019068virion assembly3.86e-041.00e+006.0852217
GO:0007220Notch receptor processing6.52e-041.00e+005.7132222
GO:0005844polysome7.14e-041.00e+005.6492223
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway8.44e-041.00e+005.5282225
GO:0005978glycogen biosynthetic process9.14e-041.00e+005.4722226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia9.14e-041.00e+005.4722226
GO:0032480negative regulation of type I interferon production1.39e-031.00e+005.1722232
GO:0022605oogenesis stage1.73e-031.00e+009.172111
GO:0021691cerebellar Purkinje cell layer maturation1.73e-031.00e+009.172111
GO:0000082G1/S transition of mitotic cell cycle2.10e-031.00e+003.53839149
GO:0007249I-kappaB kinase/NF-kappaB signaling2.27e-031.00e+004.8152341
GO:0043005neuron projection2.44e-031.00e+003.46336157
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway2.49e-031.00e+004.7462243
GO:0007254JNK cascade3.23e-031.00e+004.5582349
GO:0071338positive regulation of hair follicle cell proliferation3.46e-031.00e+008.172112
GO:0060661submandibular salivary gland formation3.46e-031.00e+008.172112
GO:1902255positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator3.46e-031.00e+008.172112
GO:0090135actin filament branching3.46e-031.00e+008.172112
GO:0030666endocytic vesicle membrane3.77e-031.00e+004.4442253
GO:0051403stress-activated MAPK cascade3.91e-031.00e+004.4172354
GO:0007173epidermal growth factor receptor signaling pathway4.12e-031.00e+003.19534189
GO:0032481positive regulation of type I interferon production4.96e-031.00e+004.2412361
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway4.96e-031.00e+004.2412261
GO:0006417regulation of translation5.12e-031.00e+004.2182262
GO:0034191apolipoprotein A-I receptor binding5.19e-031.00e+007.587113
GO:0003161cardiac conduction system development5.19e-031.00e+007.587113
GO:0050779RNA destabilization5.19e-031.00e+007.587113
GO:0000056ribosomal small subunit export from nucleus5.19e-031.00e+007.587123
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest5.44e-031.00e+004.1722664
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.61e-031.00e+004.1502665
GO:0034166toll-like receptor 10 signaling pathway5.61e-031.00e+004.1502465
GO:0034146toll-like receptor 5 signaling pathway5.61e-031.00e+004.1502465
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.48e-031.00e+004.0432870
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway6.66e-031.00e+004.0222471
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway6.66e-031.00e+004.0222471
GO:0034162toll-like receptor 9 signaling pathway6.85e-031.00e+004.0022472
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent6.85e-031.00e+004.0022672
GO:0003729mRNA binding6.85e-031.00e+004.0022272
GO:0030490maturation of SSU-rRNA6.92e-031.00e+007.172124
GO:0048664neuron fate determination6.92e-031.00e+007.172114
GO:0060020Bergmann glial cell differentiation6.92e-031.00e+007.172114
GO:0060684epithelial-mesenchymal cell signaling6.92e-031.00e+007.172114
GO:0051835positive regulation of synapse structural plasticity6.92e-031.00e+007.172114
GO:0034134toll-like receptor 2 signaling pathway7.03e-031.00e+003.9822473
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.22e-031.00e+003.9632874
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I7.41e-031.00e+003.9432675
GO:0035666TRIF-dependent toll-like receptor signaling pathway7.60e-031.00e+003.9242476
GO:0002756MyD88-independent toll-like receptor signaling pathway7.99e-031.00e+003.8872478
GO:0034138toll-like receptor 3 signaling pathway8.19e-031.00e+003.8682479
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process8.19e-031.00e+003.8682879
GO:0002755MyD88-dependent toll-like receptor signaling pathway8.39e-031.00e+003.8502480
GO:0043025neuronal cell body8.45e-031.00e+002.82134245
GO:0036336dendritic cell migration8.64e-031.00e+006.850115
GO:0035088establishment or maintenance of apical/basal cell polarity8.64e-031.00e+006.850115
GO:1902188positive regulation of viral release from host cell8.64e-031.00e+006.850115
GO:0031256leading edge membrane8.64e-031.00e+006.850115
GO:0050852T cell receptor signaling pathway9.43e-031.00e+003.7632285
GO:0007097nuclear migration1.04e-021.00e+006.587116
GO:0003334keratinocyte development1.04e-021.00e+006.587116
GO:0002309T cell proliferation involved in immune response1.04e-021.00e+006.587116
GO:0060789hair follicle placode formation1.04e-021.00e+006.587116
GO:0043196varicosity1.04e-021.00e+006.587116
GO:0048554positive regulation of metalloenzyme activity1.04e-021.00e+006.587116
GO:0006924activation-induced cell death of T cells1.04e-021.00e+006.587116
GO:0043497regulation of protein heterodimerization activity1.04e-021.00e+006.587116
GO:0050792regulation of viral process1.04e-021.00e+006.587116
GO:0000187activation of MAPK activity1.05e-021.00e+003.6802290
GO:0043065positive regulation of apoptotic process1.08e-021.00e+002.69136268
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.10e-021.00e+003.6492692
GO:0001649osteoblast differentiation1.10e-021.00e+003.6492392
GO:0071456cellular response to hypoxia1.10e-021.00e+003.6492392
GO:0034142toll-like receptor 4 signaling pathway1.19e-021.00e+003.5872496
GO:0048027mRNA 5'-UTR binding1.21e-021.00e+006.365117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.21e-021.00e+006.365117
GO:0034101erythrocyte homeostasis1.21e-021.00e+006.365117
GO:0051489regulation of filopodium assembly1.21e-021.00e+006.365117
GO:0030157pancreatic juice secretion1.21e-021.00e+006.365117
GO:0039702viral budding via host ESCRT complex1.38e-021.00e+006.172118
GO:0002224toll-like receptor signaling pathway1.52e-021.00e+003.40424109
GO:0090136epithelial cell-cell adhesion1.55e-021.00e+006.002119
GO:0047497mitochondrion transport along microtubule1.55e-021.00e+006.002119
GO:0005031tumor necrosis factor-activated receptor activity1.55e-021.00e+006.002119
GO:0097190apoptotic signaling pathway1.62e-021.00e+003.35223113
GO:0000209protein polyubiquitination1.71e-021.00e+003.31427116
GO:0031274positive regulation of pseudopodium assembly1.72e-021.00e+005.8501210
GO:0070307lens fiber cell development1.72e-021.00e+005.8501110
GO:0005798Golgi-associated vesicle1.72e-021.00e+005.8501110
GO:0060047heart contraction1.72e-021.00e+005.8501110
GO:0006006glucose metabolic process1.76e-021.00e+003.29023118
GO:0007219Notch signaling pathway1.82e-021.00e+003.26523120
GO:0045109intermediate filament organization1.89e-021.00e+005.7131111
GO:0014002astrocyte development1.89e-021.00e+005.7131211
GO:0051092positive regulation of NF-kappaB transcription factor activity1.93e-021.00e+003.21823124
GO:0007179transforming growth factor beta receptor signaling pathway2.05e-021.00e+003.17223128
GO:0061136regulation of proteasomal protein catabolic process2.06e-021.00e+005.5871112
GO:1903543positive regulation of exosomal secretion2.06e-021.00e+005.5871112
GO:1901214regulation of neuron death2.06e-021.00e+005.5871112
GO:0003723RNA binding2.07e-021.00e+002.33938342
GO:0031929TOR signaling2.23e-021.00e+005.4721113
GO:0000086G2/M transition of mitotic cell cycle2.30e-021.00e+003.08525136
GO:0000139Golgi membrane2.38e-021.00e+002.26136361
GO:0031333negative regulation of protein complex assembly2.40e-021.00e+005.3651114
GO:0031996thioesterase binding2.40e-021.00e+005.3651114
GO:0030131clathrin adaptor complex2.40e-021.00e+005.3651214
GO:0051044positive regulation of membrane protein ectodomain proteolysis2.40e-021.00e+005.3651114
GO:0048821erythrocyte development2.57e-021.00e+005.2651115
GO:0030225macrophage differentiation2.57e-021.00e+005.2651115
GO:0031369translation initiation factor binding2.57e-021.00e+005.2651115
GO:0051233spindle midzone2.57e-021.00e+005.2651215
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling2.59e-021.00e+002.99223145
GO:0010628positive regulation of gene expression2.62e-021.00e+002.98224146
GO:0034220ion transmembrane transport2.72e-021.00e+002.95322149
GO:0042176regulation of protein catabolic process2.74e-021.00e+005.1721316
GO:0005212structural constituent of eye lens2.74e-021.00e+005.1721116
GO:0008284positive regulation of cell proliferation2.75e-021.00e+002.18037382
GO:0042981regulation of apoptotic process2.76e-021.00e+002.94327150
GO:0010008endosome membrane2.79e-021.00e+002.93425151
GO:0030742GTP-dependent protein binding2.91e-021.00e+005.0851117
GO:0090316positive regulation of intracellular protein transport2.91e-021.00e+005.0851117
GO:0008543fibroblast growth factor receptor signaling pathway2.96e-021.00e+002.88723156
GO:0007088regulation of mitosis3.08e-021.00e+005.0021118
GO:0046847filopodium assembly3.24e-021.00e+004.9241119
GO:0007369gastrulation3.24e-021.00e+004.9241119
GO:0038095Fc-epsilon receptor signaling pathway3.40e-021.00e+002.78023168
GO:0051881regulation of mitochondrial membrane potential3.41e-021.00e+004.8501120
GO:0043473pigmentation3.41e-021.00e+004.8501120
GO:0031435mitogen-activated protein kinase kinase kinase binding3.58e-021.00e+004.7801121
GO:0043066negative regulation of apoptotic process3.59e-021.00e+002.029313424
GO:0031424keratinization3.75e-021.00e+004.7131122
GO:0045787positive regulation of cell cycle3.75e-021.00e+004.7131222
GO:1900026positive regulation of substrate adhesion-dependent cell spreading3.91e-021.00e+004.6491123
GO:0002040sprouting angiogenesis3.91e-021.00e+004.6491123
GO:0051017actin filament bundle assembly3.91e-021.00e+004.6491123
GO:0005737cytoplasm4.00e-021.00e+000.75211433767
GO:0006367transcription initiation from RNA polymerase II promoter4.01e-021.00e+002.64923184
GO:0007163establishment or maintenance of cell polarity4.08e-021.00e+004.5871124
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity4.41e-021.00e+004.4721226
GO:0045859regulation of protein kinase activity4.41e-021.00e+004.4721126
GO:0051149positive regulation of muscle cell differentiation4.58e-021.00e+004.4171127
GO:0032467positive regulation of cytokinesis4.58e-021.00e+004.4171127
GO:0045184establishment of protein localization4.58e-021.00e+004.4171227
GO:0031069hair follicle morphogenesis4.58e-021.00e+004.4171127
GO:0031252cell leading edge4.75e-021.00e+004.3651128
GO:0033209tumor necrosis factor-mediated signaling pathway4.75e-021.00e+004.3651128
GO:0010977negative regulation of neuron projection development4.75e-021.00e+004.3651128
GO:0072686mitotic spindle4.91e-021.00e+004.3141129
GO:0005515protein binding5.07e-021.00e+000.52315626024
GO:0031647regulation of protein stability5.08e-021.00e+004.2651130
GO:0042254ribosome biogenesis5.08e-021.00e+004.2651130
GO:0048812neuron projection morphogenesis5.24e-021.00e+004.2181231
GO:0001890placenta development5.24e-021.00e+004.2181131
GO:0007093mitotic cell cycle checkpoint5.24e-021.00e+004.2181131
GO:0033077T cell differentiation in thymus5.57e-021.00e+004.1281133
GO:0019221cytokine-mediated signaling pathway5.57e-021.00e+002.38422221
GO:0005730nucleolus5.71e-021.00e+001.0776241641
GO:0097110scaffold protein binding5.73e-021.00e+004.0851134
GO:0042692muscle cell differentiation5.73e-021.00e+004.0851134
GO:0034332adherens junction organization6.06e-021.00e+004.0021236
GO:0045740positive regulation of DNA replication6.06e-021.00e+004.0021136
GO:0030218erythrocyte differentiation6.22e-021.00e+003.9631237
GO:0030049muscle filament sliding6.39e-021.00e+003.9241238
GO:0097191extrinsic apoptotic signaling pathway6.39e-021.00e+003.9241238
GO:0006915apoptotic process6.96e-021.00e+001.64139555
GO:0071363cellular response to growth factor stimulus7.04e-021.00e+003.7801142
GO:0005975carbohydrate metabolic process7.06e-021.00e+002.18923253
GO:0021762substantia nigra development7.36e-021.00e+003.7131144
GO:0034613cellular protein localization7.36e-021.00e+003.7131244
GO:0045727positive regulation of translation7.36e-021.00e+003.7131144
GO:0008344adult locomotory behavior7.36e-021.00e+003.7131144
GO:0000122negative regulation of transcription from RNA polymerase II promoter7.42e-021.00e+001.60237570
GO:0006281DNA repair7.45e-021.00e+002.14424261
GO:0044297cell body7.68e-021.00e+003.6491146
GO:0043525positive regulation of neuron apoptotic process7.68e-021.00e+003.6491246
GO:0045111intermediate filament cytoskeleton7.84e-021.00e+003.6181147
GO:0006921cellular component disassembly involved in execution phase of apoptosis7.84e-021.00e+003.6181147
GO:0048011neurotrophin TRK receptor signaling pathway7.85e-021.00e+002.10124269
GO:0007030Golgi organization8.16e-021.00e+003.5581249
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage8.16e-021.00e+003.5581149
GO:0045087innate immune response8.24e-021.00e+001.53838596
GO:0001948glycoprotein binding8.32e-021.00e+003.5281150
GO:0030175filopodium8.32e-021.00e+003.5281250
GO:0003725double-stranded RNA binding8.64e-021.00e+003.4721152
GO:0046330positive regulation of JNK cascade9.12e-021.00e+003.3911155
GO:0050728negative regulation of inflammatory response9.28e-021.00e+003.3651156
GO:0005793endoplasmic reticulum-Golgi intermediate compartment9.28e-021.00e+003.3651156
GO:0033138positive regulation of peptidyl-serine phosphorylation9.75e-021.00e+003.2901159
GO:0005882intermediate filament1.01e-011.00e+003.2411261
GO:0030141secretory granule1.02e-011.00e+003.2181162
GO:0019901protein kinase binding1.04e-011.00e+001.86426317
GO:0043231intracellular membrane-bounded organelle1.04e-011.00e+001.85925318
GO:0031295T cell costimulation1.07e-011.00e+003.1501365
GO:0035264multicellular organism growth1.10e-011.00e+003.1061167
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.21e-011.00e+002.9631274
GO:0060070canonical Wnt signaling pathway1.22e-011.00e+002.9431175
GO:0010629negative regulation of gene expression1.25e-011.00e+002.9051277
GO:0031902late endosome membrane1.25e-011.00e+002.9051277
GO:0005179hormone activity1.28e-011.00e+002.8681179
GO:0045177apical part of cell1.31e-011.00e+002.8321181
GO:0071222cellular response to lipopolysaccharide1.31e-011.00e+002.8321381
GO:0005777peroxisome1.36e-011.00e+002.7801184
GO:0042593glucose homeostasis1.40e-011.00e+002.7291187
GO:0000278mitotic cell cycle1.46e-011.00e+001.561211391
GO:0006928cellular component movement1.46e-011.00e+002.6641191
GO:0005200structural constituent of cytoskeleton1.46e-011.00e+002.6641391
GO:0030496midbody1.71e-011.00e+002.41712108
GO:0055085transmembrane transport1.73e-011.00e+001.40723435
GO:0005815microtubule organizing center1.73e-011.00e+002.40413109
GO:0051056regulation of small GTPase mediated signal transduction1.82e-011.00e+002.32714115
GO:0007568aging1.84e-011.00e+002.30211117
GO:0030036actin cytoskeleton organization1.93e-011.00e+002.23012123
GO:0009615response to virus1.97e-011.00e+002.19512126
GO:0042802identical protein binding2.04e-011.00e+001.25323484
GO:0005911cell-cell junction2.11e-011.00e+002.08512136
GO:0048471perinuclear region of cytoplasm2.16e-011.00e+001.20127502
GO:0008286insulin receptor signaling pathway2.19e-011.00e+002.02213142
GO:0045121membrane raft2.38e-011.00e+001.88713156
GO:0008022protein C-terminus binding2.45e-011.00e+001.84113161
GO:0031625ubiquitin protein ligase binding2.67e-011.00e+001.69612178
GO:0019904protein domain specific binding2.68e-011.00e+001.68813179
GO:0005886plasma membrane2.83e-011.00e+000.4236202582
GO:0005794Golgi apparatus2.86e-011.00e+000.92029610
GO:0005654nucleoplasm2.88e-011.00e+000.6783151082
GO:0003924GTPase activity2.91e-011.00e+001.55017197
GO:0006184GTP catabolic process3.12e-011.00e+001.43117214
GO:0007067mitotic nuclear division3.28e-011.00e+001.34615227
GO:0030425dendrite3.31e-011.00e+001.32712230
GO:0000166nucleotide binding3.65e-011.00e+001.15512259
GO:0006954inflammatory response3.84e-011.00e+001.05811277
GO:0007264small GTPase mediated signal transduction3.87e-011.00e+001.04817279
GO:0006955immune response3.96e-011.00e+001.00212288
GO:0005856cytoskeleton3.99e-011.00e+000.98714291
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.01e-011.00e+000.54826789
GO:0005525GTP binding4.19e-011.00e+000.89617310
GO:0007275multicellular organismal development4.26e-011.00e+000.86811316
GO:0007411axon guidance4.29e-011.00e+000.85513319
GO:0015031protein transport4.50e-011.00e+000.75918341
GO:0005739mitochondrion5.24e-011.00e+000.20928998
GO:0007596blood coagulation5.52e-011.00e+000.34313455
GO:0005634nucleus5.58e-011.00e+000.0188434559
GO:0005783endoplasmic reticulum6.26e-011.00e+000.05313556
GO:0044281small molecule metabolic process6.33e-011.00e+00-0.0702151211
GO:0006351transcription, DNA-templated7.30e-011.00e+00-0.326261446
GO:0005576extracellular region8.15e-011.00e+00-0.70713942
GO:0005615extracellular space8.21e-011.00e+00-0.73012957
GO:0003677DNA binding8.90e-011.00e+00-1.078131218
GO:0046872metal ion binding9.07e-011.00e+00-1.1801101307
GO:0016021integral component of membrane9.75e-011.00e+00-1.781151982