int-snw-400

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	8.046	6.96e-234	5.12e-13	5.58e-06

tai-screen-luciferase-int-snw-400 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
COPZ1	22818	32	-8.301	9.063	13	Yes	Yes
COPA	1314	32	-9.395	9.063	170	Yes	Yes
RPS26	6231	17	-7.478	8.046	60	Yes	-
ARCN1	372	32	-8.232	9.063	118	Yes	Yes
[ ARL1 ]	400	4	-4.142	8.046	110	-	Yes
COPB2	9276	32	-13.168	9.063	41	Yes	Yes
RPS6	6194	17	-5.603	8.046	208	Yes	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ARL1	400	COPA	1314	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
ARCN1	372	ARL1	400	pp	--	int.I2D: BioGrid_Yeast
ARL1	400	RPS6	6194	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS26	6231	pp	--	int.I2D: YeastLow
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo

Related GO terms (83)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0030126	COPI vesicle coat	9.60e-12	1.38e-07	9.424	4	7	12
GO:0048205	COPI coating of Golgi vesicle	1.39e-11	2.00e-07	9.308	4	8	13
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.45e-10	3.53e-06	8.365	4	8	25
GO:0061024	membrane organization	3.35e-07	4.83e-03	5.829	4	12	145
GO:0006886	intracellular protein transport	6.49e-07	9.37e-03	5.591	4	7	171
GO:0015935	small ribosomal subunit	2.74e-05	3.95e-01	7.921	2	9	17
GO:0006891	intra-Golgi vesicle-mediated transport	2.74e-05	3.95e-01	7.921	2	4	17
GO:0022627	cytosolic small ribosomal subunit	1.48e-04	1.00e+00	6.723	2	20	39
GO:0005829	cytosol	1.59e-04	1.00e+00	2.308	6	61	2496
GO:0021691	cerebellar Purkinje cell layer maturation	4.85e-04	1.00e+00	11.009	1	1	1
GO:0022605	oogenesis stage	4.85e-04	1.00e+00	11.009	1	1	1
GO:0019083	viral transcription	6.42e-04	1.00e+00	5.669	2	20	81
GO:0006415	translational termination	7.41e-04	1.00e+00	5.566	2	20	87
GO:0006414	translational elongation	8.46e-04	1.00e+00	5.470	2	20	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.06e-03	1.00e+00	5.308	2	20	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.27e-03	1.00e+00	5.176	2	20	114
GO:0019058	viral life cycle	1.29e-03	1.00e+00	5.163	2	23	115
GO:0009404	toxin metabolic process	1.46e-03	1.00e+00	9.424	1	1	3
GO:0006413	translational initiation	1.67e-03	1.00e+00	4.975	2	21	131
GO:0003735	structural constituent of ribosome	1.82e-03	1.00e+00	4.911	2	22	137
GO:0005198	structural molecule activity	2.18e-03	1.00e+00	4.780	2	6	150
GO:0031584	activation of phospholipase D activity	2.42e-03	1.00e+00	8.687	1	1	5
GO:0033119	negative regulation of RNA splicing	2.42e-03	1.00e+00	8.687	1	2	5
GO:0006924	activation-induced cell death of T cells	2.91e-03	1.00e+00	8.424	1	1	6
GO:0002309	T cell proliferation involved in immune response	2.91e-03	1.00e+00	8.424	1	1	6
GO:0030157	pancreatic juice secretion	3.39e-03	1.00e+00	8.201	1	1	7
GO:0048193	Golgi vesicle transport	3.39e-03	1.00e+00	8.201	1	1	7
GO:0034067	protein localization to Golgi apparatus	3.39e-03	1.00e+00	8.201	1	1	7
GO:0000028	ribosomal small subunit assembly	3.39e-03	1.00e+00	8.201	1	3	7
GO:0016071	mRNA metabolic process	4.75e-03	1.00e+00	4.208	2	25	223
GO:0016020	membrane	4.81e-03	1.00e+00	2.294	4	41	1681
GO:0006412	translation	5.04e-03	1.00e+00	4.163	2	23	230
GO:0016070	RNA metabolic process	5.80e-03	1.00e+00	4.060	2	25	247
GO:0042274	ribosomal small subunit biogenesis	5.81e-03	1.00e+00	7.424	1	6	12
GO:0031929	TOR signaling	6.29e-03	1.00e+00	7.308	1	1	13
GO:0030131	clathrin adaptor complex	6.78e-03	1.00e+00	7.201	1	2	14
GO:0048821	erythrocyte development	7.26e-03	1.00e+00	7.102	1	1	15
GO:0007369	gastrulation	9.19e-03	1.00e+00	6.761	1	1	19
GO:0043473	pigmentation	9.67e-03	1.00e+00	6.687	1	1	20
GO:0036464	cytoplasmic ribonucleoprotein granule	1.06e-02	1.00e+00	6.549	1	3	22
GO:0044822	poly(A) RNA binding	1.10e-02	1.00e+00	2.549	3	32	1056
GO:0005844	polysome	1.11e-02	1.00e+00	6.485	1	2	23
GO:0001890	placenta development	1.50e-02	1.00e+00	6.055	1	1	31
GO:0007093	mitotic cell cycle checkpoint	1.50e-02	1.00e+00	6.055	1	1	31
GO:0005737	cytoplasm	1.56e-02	1.00e+00	1.451	5	43	3767
GO:0033077	T cell differentiation in thymus	1.59e-02	1.00e+00	5.964	1	1	33
GO:0008047	enzyme activator activity	1.88e-02	1.00e+00	5.723	1	1	39
GO:0042147	retrograde transport, endosome to Golgi	1.97e-02	1.00e+00	5.651	1	1	41
GO:0044267	cellular protein metabolic process	2.03e-02	1.00e+00	3.120	2	23	474
GO:0008344	adult locomotory behavior	2.12e-02	1.00e+00	5.549	1	1	44
GO:0044297	cell body	2.21e-02	1.00e+00	5.485	1	1	46
GO:0007030	Golgi organization	2.35e-02	1.00e+00	5.394	1	2	49
GO:0016032	viral process	2.54e-02	1.00e+00	2.948	2	33	534
GO:0005794	Golgi apparatus	3.26e-02	1.00e+00	2.756	2	9	610
GO:0003729	mRNA binding	3.44e-02	1.00e+00	4.839	1	2	72
GO:0005179	hormone activity	3.77e-02	1.00e+00	4.705	1	1	79
GO:0010467	gene expression	3.86e-02	1.00e+00	2.623	2	29	669
GO:0042593	glucose homeostasis	4.15e-02	1.00e+00	4.566	1	1	87
GO:0006364	rRNA processing	4.47e-02	1.00e+00	4.454	1	7	94
GO:0005802	trans-Golgi network	5.22e-02	1.00e+00	4.227	1	3	110
GO:0030529	ribonucleoprotein complex	5.31e-02	1.00e+00	4.201	1	7	112
GO:0008286	insulin receptor signaling pathway	6.69e-02	1.00e+00	3.859	1	3	142
GO:0000082	G1/S transition of mitotic cell cycle	7.01e-02	1.00e+00	3.790	1	9	149
GO:0019904	protein domain specific binding	8.37e-02	1.00e+00	3.525	1	3	179
GO:0003924	GTPase activity	9.18e-02	1.00e+00	3.387	1	7	197
GO:0070062	extracellular vesicular exosome	9.54e-02	1.00e+00	1.365	3	40	2400
GO:0006184	GTP catabolic process	9.94e-02	1.00e+00	3.267	1	7	214
GO:0007067	mitotic nuclear division	1.05e-01	1.00e+00	3.182	1	5	227
GO:0030425	dendrite	1.06e-01	1.00e+00	3.163	1	2	230
GO:0043065	positive regulation of apoptotic process	1.23e-01	1.00e+00	2.943	1	6	268
GO:0007264	small GTPase mediated signal transduction	1.28e-01	1.00e+00	2.885	1	7	279
GO:0005525	GTP binding	1.41e-01	1.00e+00	2.733	1	7	310
GO:0019901	protein kinase binding	1.44e-01	1.00e+00	2.700	1	6	317
GO:0043231	intracellular membrane-bounded organelle	1.45e-01	1.00e+00	2.696	1	5	318
GO:0000139	Golgi membrane	1.63e-01	1.00e+00	2.513	1	6	361
GO:0005730	nucleolus	1.85e-01	1.00e+00	1.328	2	24	1641
GO:0043066	negative regulation of apoptotic process	1.89e-01	1.00e+00	2.281	1	13	424
GO:0048471	perinuclear region of cytoplasm	2.20e-01	1.00e+00	2.037	1	7	502
GO:0005783	endoplasmic reticulum	2.41e-01	1.00e+00	1.890	1	3	556
GO:0005615	extracellular space	3.82e-01	1.00e+00	1.106	1	2	957
GO:0046872	metal ion binding	4.86e-01	1.00e+00	0.657	1	10	1307
GO:0005515	protein binding	8.63e-01	1.00e+00	-0.548	2	62	6024
GO:0005634	nucleus	9.30e-01	1.00e+00	-1.146	1	43	4559

Tai-Luciferase

int-snw-400

Statistics

Genes (7)

Interactions (9)

Related GO terms (83)