int-snw-2800

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 6.833 2.39e-160 1.44e-08 6.25e-04
tai-screen-luciferase-int-snw-2800 subnetwork

Genes (14)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS4X 6191 18-6.7477.555263Yes-
COPZ1 22818 32-8.3019.06313YesYes
ATP6V1D 51382 8-4.1317.286149--
COPA 1314 32-9.3959.063170YesYes
ARL1 400 4-4.1428.046110-Yes
RPS11 6205 17-6.5887.555175Yes-
RPS6 6194 17-5.6038.046208Yes-
RPS24 6229 21-7.0348.389217Yes-
RPS26 6231 17-7.4788.04660Yes-
ARCN1 372 32-8.2329.063118YesYes
[ GOLGA1 ] 2800 12.0296.8335--
COPB1 1315 22-6.2219.063118YesYes
COPB2 9276 32-13.1689.06341YesYes
RPS13 6207 17-6.5897.555174Yes-

Interactions (29)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ARL1 400 COPA 1314 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
RPS11 6205 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
COPA 1314 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
ARCN1 372 ARL1 400 pp -- int.I2D: BioGrid_Yeast
ARL1 400 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ARL1 400 GOLGA1 2800 pp -- int.I2D: BCI, BioGrid, HPRD;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ARL1 400 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)

Related GO terms (112)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0030126COPI vesicle coat3.04e-134.38e-098.7465712
GO:0048205COPI coating of Golgi vesicle4.94e-137.12e-098.6305813
GO:0022627cytosolic small ribosomal subunit7.72e-131.11e-087.30862039
GO:0006890retrograde vesicle-mediated transport, Golgi to ER2.03e-112.92e-077.6875825
GO:0019083viral transcription7.53e-111.09e-066.25462081
GO:0006415translational termination1.17e-101.68e-066.15162087
GO:0006414translational elongation1.76e-102.54e-066.05562093
GO:0006614SRP-dependent cotranslational protein targeting to membrane3.48e-105.02e-065.893620104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay6.09e-108.78e-065.761620114
GO:0019058viral life cycle6.42e-109.26e-065.748623115
GO:0015935small ribosomal subunit1.31e-091.89e-057.9214917
GO:0006413translational initiation1.42e-092.04e-055.560621131
GO:0003735structural constituent of ribosome1.86e-092.68e-055.496622137
GO:0016071mRNA metabolic process3.46e-084.99e-044.793625223
GO:0006412translation4.16e-086.00e-044.748623230
GO:0005829cytosol4.54e-086.55e-042.30812612496
GO:0016070RNA metabolic process6.36e-089.17e-044.645625247
GO:0061024membrane organization1.78e-072.57e-035.151512145
GO:0016032viral process2.51e-073.62e-033.755733534
GO:0016020membrane2.90e-074.18e-032.61610411681
GO:0006886intracellular protein transport4.06e-075.85e-034.91357171
GO:0006891intra-Golgi vesicle-mediated transport4.91e-077.08e-037.5063417
GO:0044267cellular protein metabolic process2.93e-064.22e-023.705623474
GO:0033119negative regulation of RNA splicing8.74e-061.26e-018.687225
GO:0010467gene expression2.12e-053.06e-013.208629669
GO:0005840ribosome2.18e-053.14e-015.7363858
GO:0044822poly(A) RNA binding2.40e-053.46e-012.7727321056
GO:0042274ribosomal small subunit biogenesis5.74e-058.28e-017.4242612
GO:0036464cytoplasmic ribonucleoprotein granule2.00e-041.00e+006.5492322
GO:0005844polysome2.19e-041.00e+006.4852223
GO:0019843rRNA binding3.03e-041.00e+006.2542427
GO:0005198structural molecule activity3.69e-041.00e+004.36536150
GO:0033176proton-transporting V-type ATPase complex9.71e-041.00e+0010.009111
GO:0021691cerebellar Purkinje cell layer maturation9.71e-041.00e+0010.009111
GO:0022605oogenesis stage9.71e-041.00e+0010.009111
GO:0003729mRNA binding2.15e-031.00e+004.8392272
GO:0005794Golgi apparatus2.26e-031.00e+002.75649610
GO:0009404toxin metabolic process2.91e-031.00e+008.424113
GO:0043231intracellular membrane-bounded organelle3.23e-031.00e+003.28135318
GO:0006364rRNA processing3.63e-031.00e+004.4542794
GO:0070062extracellular vesicular exosome4.05e-031.00e+001.5877402400
GO:0005925focal adhesion4.79e-031.00e+003.078319366
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.84e-031.00e+007.687135
GO:0031584activation of phospholipase D activity4.84e-031.00e+007.687115
GO:0005802trans-Golgi network4.94e-031.00e+004.22723110
GO:0030529ribonucleoprotein complex5.12e-031.00e+004.20127112
GO:0061512protein localization to cilium5.81e-031.00e+007.424116
GO:0006924activation-induced cell death of T cells5.81e-031.00e+007.424116
GO:0002309T cell proliferation involved in immune response5.81e-031.00e+007.424116
GO:0034101erythrocyte homeostasis6.78e-031.00e+007.201117
GO:0030157pancreatic juice secretion6.78e-031.00e+007.201117
GO:0048193Golgi vesicle transport6.78e-031.00e+007.201117
GO:0034067protein localization to Golgi apparatus6.78e-031.00e+007.201117
GO:0000028ribosomal small subunit assembly6.78e-031.00e+007.201137
GO:0008286insulin receptor signaling pathway8.11e-031.00e+003.85923142
GO:0005798Golgi-associated vesicle9.67e-031.00e+006.6871110
GO:0000042protein targeting to Golgi1.06e-021.00e+006.5491111
GO:0031929TOR signaling1.26e-021.00e+006.3081113
GO:0030131clathrin adaptor complex1.35e-021.00e+006.2011214
GO:0031369translation initiation factor binding1.45e-021.00e+006.1021115
GO:0048821erythrocyte development1.45e-021.00e+006.1021115
GO:0007369gastrulation1.83e-021.00e+005.7611119
GO:0043473pigmentation1.92e-021.00e+005.6871120
GO:0042626ATPase activity, coupled to transmembrane movement of substances2.50e-021.00e+005.3081126
GO:0015992proton transport2.78e-021.00e+005.1511129
GO:0033572transferrin transport2.87e-021.00e+005.1021130
GO:0001890placenta development2.97e-021.00e+005.0551131
GO:0007093mitotic cell cycle checkpoint2.97e-021.00e+005.0551131
GO:0051701interaction with host3.06e-021.00e+005.0091132
GO:0033077T cell differentiation in thymus3.16e-021.00e+004.9641133
GO:0090382phagosome maturation3.44e-021.00e+004.8391136
GO:0008047enzyme activator activity3.72e-021.00e+004.7231139
GO:0042147retrograde transport, endosome to Golgi3.91e-021.00e+004.6511141
GO:0045727positive regulation of translation4.19e-021.00e+004.5491144
GO:0008344adult locomotory behavior4.19e-021.00e+004.5491144
GO:0032580Golgi cisterna membrane4.28e-021.00e+004.5171145
GO:0044297cell body4.38e-021.00e+004.4851146
GO:0007030Golgi organization4.65e-021.00e+004.3941249
GO:0000139Golgi membrane4.66e-021.00e+002.51326361
GO:0005737cytoplasm4.77e-021.00e+000.9377433767
GO:0006879cellular iron ion homeostasis4.84e-021.00e+004.3361151
GO:0005793endoplasmic reticulum-Golgi intermediate compartment5.30e-021.00e+004.2011156
GO:0005730nucleolus6.58e-021.00e+001.3284241641
GO:0005929cilium7.22e-021.00e+003.7421177
GO:0005179hormone activity7.40e-021.00e+003.7051179
GO:0042384cilium assembly8.04e-021.00e+003.5821186
GO:0042593glucose homeostasis8.13e-021.00e+003.5661187
GO:0048471perinuclear region of cytoplasm8.35e-021.00e+002.03727502
GO:0001649osteoblast differentiation8.57e-021.00e+003.4851392
GO:0000082G1/S transition of mitotic cell cycle1.35e-011.00e+002.79019149
GO:0019904protein domain specific binding1.60e-011.00e+002.52513179
GO:0003924GTPase activity1.75e-011.00e+002.38717197
GO:0005765lysosomal membrane1.80e-011.00e+002.34312203
GO:0006184GTP catabolic process1.89e-011.00e+002.26717214
GO:0007067mitotic nuclear division1.99e-011.00e+002.18215227
GO:0030425dendrite2.02e-011.00e+002.16312230
GO:0000166nucleotide binding2.24e-011.00e+001.99212259
GO:0043065positive regulation of apoptotic process2.31e-011.00e+001.94316268
GO:0007264small GTPase mediated signal transduction2.39e-011.00e+001.88517279
GO:0005525GTP binding2.62e-011.00e+001.73317310
GO:0019901protein kinase binding2.67e-011.00e+001.70016317
GO:0007275multicellular organismal development2.67e-011.00e+001.70511316
GO:0005813centrosome2.74e-011.00e+001.66015326
GO:0008284positive regulation of cell proliferation3.13e-011.00e+001.43117382
GO:0043066negative regulation of apoptotic process3.42e-011.00e+001.281113424
GO:0055085transmembrane transport3.49e-011.00e+001.24413435
GO:0005783endoplasmic reticulum4.23e-011.00e+000.89013556
GO:0005515protein binding5.68e-011.00e+000.0376626024
GO:0005615extracellular space6.18e-011.00e+000.10612957
GO:0046872metal ion binding7.36e-011.00e+00-0.3431101307
GO:0005634nucleus8.68e-011.00e+00-0.5613434559
GO:0005886plasma membrane9.37e-011.00e+00-1.3261202582