int-snw-1315
Statistics
| Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
|---|---|---|---|---|
| tai-screen-luciferase | 9.063 | 1.00e-306 | 1.35e-17 | 3.55e-08 |
Genes (5)
| Gene Symbol | Entrez Gene ID | Frequency | tai-screen-luciferase gene score | Best subnetwork score | Degree | List-Gonzales GI | Tai-Hits |
|---|---|---|---|---|---|---|---|
| COPZ1 | 22818 | 32 | -8.301 | 9.063 | 13 | Yes | Yes |
| COPA | 1314 | 32 | -9.395 | 9.063 | 170 | Yes | Yes |
| ARCN1 | 372 | 32 | -8.232 | 9.063 | 118 | Yes | Yes |
| COPB2 | 9276 | 32 | -13.168 | 9.063 | 41 | Yes | Yes |
| [ COPB1 ] | 1315 | 22 | -6.221 | 9.063 | 118 | Yes | Yes |
Interactions (9)
| Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
|---|---|---|---|---|---|---|
| COPA | 1314 | COPB1 | 1315 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh |
| ARCN1 | 372 | COPB1 | 1315 | pp | -- | int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo |
| ARCN1 | 372 | COPA | 1314 | pp | -- | int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo |
| ARCN1 | 372 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG |
| COPA | 1314 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo |
| ARCN1 | 372 | COPB2 | 9276 | pp | -- | int.I2D: HPRD, BCI; int.HPRD: in vivo |
| COPA | 1314 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium |
| COPB1 | 1315 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid |
| COPB1 | 1315 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association) |
Related GO terms (28)
| Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
|---|---|---|---|---|---|---|---|
| GO:0030126 | COPI vesicle coat | 1.52e-16 | 2.20e-12 | 10.231 | 5 | 7 | 12 |
| GO:0048205 | COPI coating of Golgi vesicle | 2.48e-16 | 3.57e-12 | 10.116 | 5 | 8 | 13 |
| GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | 1.02e-14 | 1.47e-10 | 9.172 | 5 | 8 | 25 |
| GO:0061024 | membrane organization | 9.59e-11 | 1.38e-06 | 6.636 | 5 | 12 | 145 |
| GO:0006886 | intracellular protein transport | 2.21e-10 | 3.19e-06 | 6.398 | 5 | 7 | 171 |
| GO:0006891 | intra-Golgi vesicle-mediated transport | 1.36e-08 | 1.96e-04 | 8.992 | 3 | 4 | 17 |
| GO:0005198 | structural molecule activity | 1.09e-05 | 1.57e-01 | 5.850 | 3 | 6 | 150 |
| GO:0005829 | cytosol | 1.55e-04 | 1.00e+00 | 2.531 | 5 | 61 | 2496 |
| GO:0021691 | cerebellar Purkinje cell layer maturation | 3.47e-04 | 1.00e+00 | 11.494 | 1 | 1 | 1 |
| GO:0030157 | pancreatic juice secretion | 2.42e-03 | 1.00e+00 | 8.687 | 1 | 1 | 7 |
| GO:0005798 | Golgi-associated vesicle | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 1 | 10 |
| GO:0043231 | intracellular membrane-bounded organelle | 4.64e-03 | 1.00e+00 | 4.181 | 2 | 5 | 318 |
| GO:0030131 | clathrin adaptor complex | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 2 | 14 |
| GO:0043473 | pigmentation | 6.92e-03 | 1.00e+00 | 7.172 | 1 | 1 | 20 |
| GO:0016020 | membrane | 1.32e-02 | 1.00e+00 | 2.364 | 3 | 41 | 1681 |
| GO:0008344 | adult locomotory behavior | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 1 | 44 |
| GO:0005794 | Golgi apparatus | 1.64e-02 | 1.00e+00 | 3.241 | 2 | 9 | 610 |
| GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment | 1.93e-02 | 1.00e+00 | 5.687 | 1 | 1 | 56 |
| GO:0005179 | hormone activity | 2.71e-02 | 1.00e+00 | 5.190 | 1 | 1 | 79 |
| GO:0005737 | cytoplasm | 1.16e-01 | 1.00e+00 | 1.200 | 3 | 43 | 3767 |
| GO:0000139 | Golgi membrane | 1.19e-01 | 1.00e+00 | 2.998 | 1 | 6 | 361 |
| GO:0016032 | viral process | 1.72e-01 | 1.00e+00 | 2.433 | 1 | 33 | 534 |
| GO:0005783 | endoplasmic reticulum | 1.78e-01 | 1.00e+00 | 2.375 | 1 | 3 | 556 |
| GO:0005615 | extracellular space | 2.91e-01 | 1.00e+00 | 1.592 | 1 | 2 | 957 |
| GO:0044822 | poly(A) RNA binding | 3.16e-01 | 1.00e+00 | 1.450 | 1 | 32 | 1056 |
| GO:0070062 | extracellular vesicular exosome | 5.98e-01 | 1.00e+00 | 0.265 | 1 | 40 | 2400 |
| GO:0005886 | plasma membrane | 6.27e-01 | 1.00e+00 | 0.160 | 1 | 20 | 2582 |
| GO:0005515 | protein binding | 9.33e-01 | 1.00e+00 | -1.062 | 1 | 62 | 6024 |