Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
tai-screen-luciferase | 6.205 | 8.63e-128 | 1.09e-06 | 4.18e-03 |
Gene Symbol | Entrez Gene ID | Frequency | tai-screen-luciferase gene score | Best subnetwork score | Degree | List-Gonzales GI | Tai-Hits |
---|---|---|---|---|---|---|---|
RPS8 | 6202 | 10 | -5.545 | 7.555 | 234 | - | - |
CHMP2A | 27243 | 10 | -9.037 | 7.555 | 41 | Yes | Yes |
COPA | 1314 | 32 | -9.395 | 9.063 | 170 | Yes | Yes |
RPS24 | 6229 | 21 | -7.034 | 8.389 | 217 | Yes | - |
[ CHKB ] | 1120 | 1 | -2.194 | 6.205 | 42 | - | - |
RPS9 | 6203 | 18 | -7.127 | 7.555 | 140 | Yes | - |
COPB2 | 9276 | 32 | -13.168 | 9.063 | 41 | Yes | Yes |
RPS4X | 6191 | 18 | -6.747 | 7.555 | 263 | Yes | - |
COPZ1 | 22818 | 32 | -8.301 | 9.063 | 13 | Yes | Yes |
PSMD1 | 5707 | 3 | -3.604 | 6.408 | 113 | - | Yes |
RPS16 | 6217 | 5 | -5.444 | 7.011 | 202 | - | - |
ATP6V1D | 51382 | 8 | -4.131 | 7.286 | 149 | - | - |
RPS27A | 6233 | 15 | -5.631 | 8.389 | 342 | Yes | - |
RPS11 | 6205 | 17 | -6.588 | 7.555 | 175 | Yes | - |
PSMD3 | 5709 | 3 | -3.935 | 6.408 | 146 | - | Yes |
ARL1 | 400 | 4 | -4.142 | 8.046 | 110 | - | Yes |
RPS6 | 6194 | 17 | -5.603 | 8.046 | 208 | Yes | - |
RPS26 | 6231 | 17 | -7.478 | 8.046 | 60 | Yes | - |
ARCN1 | 372 | 32 | -8.232 | 9.063 | 118 | Yes | Yes |
SRPK1 | 6732 | 2 | -3.733 | 7.138 | 50 | - | - |
COPB1 | 1315 | 22 | -6.221 | 9.063 | 118 | Yes | Yes |
SRPK2 | 6733 | 1 | -2.827 | 6.205 | 98 | - | - |
RPS13 | 6207 | 17 | -6.589 | 7.555 | 174 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
RPS8 | 6202 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
CHKB | 1120 | SRPK2 | 6733 | pp | -- | int.I2D: BioGrid_Yeast, Yeast_Kinome |
RPS9 | 6203 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
CHKB | 1120 | PSMD3 | 5709 | pp | -- | int.I2D: IntAct_Yeast |
RPS4X | 6191 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS9 | 6203 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG |
RPS6 | 6194 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | ARL1 | 400 | pp | -- | int.I2D: BioGrid_Yeast |
COPA | 1314 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo |
RPS16 | 6217 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS6 | 6194 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS9 | 6203 | pp | -- | int.I2D: BioGrid_Yeast |
RPS8 | 6202 | RPS9 | 6203 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast |
RPS24 | 6229 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast |
RPS13 | 6207 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
RPS8 | 6202 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
ARL1 | 400 | COPA | 1314 | pp | -- | int.I2D: BioGrid_Yeast |
ARL1 | 400 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPB2 | 9276 | pp | -- | int.I2D: HPRD, BCI; int.HPRD: in vivo |
PSMD1 | 5707 | SRPK2 | 6733 | pp | -- | int.I2D: BioGrid_Yeast, Yeast_Kinome |
COPA | 1314 | COPB1 | 1315 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh |
RPS8 | 6202 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
RPS13 | 6207 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
RPS8 | 6202 | CHMP2A | 27243 | pp | -- | int.I2D: BioGrid_Yeast |
RPS9 | 6203 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
ARL1 | 400 | RPS6 | 6194 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS8 | 6202 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RPS11 | 6205 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPB1 | 1315 | pp | -- | int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo |
RPS9 | 6203 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
COPA | 1314 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium |
COPB1 | 1315 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid |
RPS6 | 6194 | RPS26 | 6231 | pp | -- | int.I2D: YeastLow |
COPA | 1314 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
RPS6 | 6194 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
COPA | 1314 | ATP6V1D | 51382 | pp | -- | int.I2D: YeastLow |
RPS16 | 6217 | RPS26 | 6231 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast |
ARL1 | 400 | CHKB | 1120 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS8 | 6202 | pp | -- | int.I2D: BioGrid_Yeast |
RPS8 | 6202 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
PSMD1 | 5707 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core |
SRPK1 | 6732 | SRPK2 | 6733 | pp | -- | int.I2D: BioGrid, MINT |
RPS24 | 6229 | RPS27A | 6233 | pp | -- | int.I2D: YeastMedium |
COPB1 | 1315 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association) |
ARCN1 | 372 | COPA | 1314 | pp | -- | int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo |
RPS4X | 6191 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0022627 | cytosolic small ribosomal subunit | 6.64e-21 | 9.57e-17 | 7.329 | 10 | 20 | 39 |
GO:0019058 | viral life cycle | 6.34e-18 | 9.14e-14 | 5.906 | 11 | 23 | 115 |
GO:0019083 | viral transcription | 1.89e-17 | 2.73e-13 | 6.275 | 10 | 20 | 81 |
GO:0006415 | translational termination | 4.01e-17 | 5.79e-13 | 6.172 | 10 | 20 | 87 |
GO:0006414 | translational elongation | 8.07e-17 | 1.16e-12 | 6.075 | 10 | 20 | 93 |
GO:0016032 | viral process | 1.04e-16 | 1.49e-12 | 4.139 | 15 | 33 | 534 |
GO:0016071 | mRNA metabolic process | 1.62e-16 | 2.33e-12 | 5.077 | 12 | 25 | 223 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 2.58e-16 | 3.73e-12 | 5.914 | 10 | 20 | 104 |
GO:0016070 | RNA metabolic process | 5.58e-16 | 8.04e-12 | 4.929 | 12 | 25 | 247 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 6.68e-16 | 9.63e-12 | 5.782 | 10 | 20 | 114 |
GO:0006413 | translational initiation | 2.79e-15 | 4.03e-11 | 5.581 | 10 | 21 | 131 |
GO:0003735 | structural constituent of ribosome | 4.42e-15 | 6.37e-11 | 5.516 | 10 | 22 | 137 |
GO:0015935 | small ribosomal subunit | 9.89e-14 | 1.43e-09 | 7.790 | 6 | 9 | 17 |
GO:0005829 | cytosol | 5.65e-13 | 8.14e-09 | 2.329 | 20 | 61 | 2496 |
GO:0006412 | translation | 8.35e-13 | 1.20e-08 | 4.769 | 10 | 23 | 230 |
GO:0030126 | COPI vesicle coat | 5.09e-12 | 7.34e-08 | 8.029 | 5 | 7 | 12 |
GO:0016020 | membrane | 6.35e-12 | 9.16e-08 | 2.665 | 17 | 41 | 1681 |
GO:0048205 | COPI coating of Golgi vesicle | 8.26e-12 | 1.19e-07 | 7.914 | 5 | 8 | 13 |
GO:0010467 | gene expression | 7.61e-11 | 1.10e-06 | 3.492 | 12 | 29 | 669 |
GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | 3.37e-10 | 4.86e-06 | 6.971 | 5 | 8 | 25 |
GO:0044822 | poly(A) RNA binding | 9.26e-10 | 1.34e-05 | 2.949 | 13 | 32 | 1056 |
GO:0044267 | cellular protein metabolic process | 1.04e-09 | 1.50e-05 | 3.726 | 10 | 23 | 474 |
GO:0061024 | membrane organization | 1.92e-09 | 2.77e-05 | 4.920 | 7 | 12 | 145 |
GO:0042274 | ribosomal small subunit biogenesis | 7.72e-07 | 1.11e-02 | 7.293 | 3 | 6 | 12 |
GO:0005840 | ribosome | 1.97e-06 | 2.84e-02 | 5.435 | 4 | 8 | 58 |
GO:0070062 | extracellular vesicular exosome | 2.19e-06 | 3.16e-02 | 1.871 | 14 | 40 | 2400 |
GO:0006891 | intra-Golgi vesicle-mediated transport | 2.37e-06 | 3.42e-02 | 6.790 | 3 | 4 | 17 |
GO:0006886 | intracellular protein transport | 6.25e-06 | 9.02e-02 | 4.197 | 5 | 7 | 171 |
GO:0019843 | rRNA binding | 1.01e-05 | 1.46e-01 | 6.123 | 3 | 4 | 27 |
GO:0005925 | focal adhesion | 1.79e-05 | 2.59e-01 | 3.362 | 6 | 19 | 366 |
GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.43e-05 | 3.50e-01 | 7.971 | 2 | 3 | 5 |
GO:0033119 | negative regulation of RNA splicing | 2.43e-05 | 3.50e-01 | 7.971 | 2 | 2 | 5 |
GO:0030529 | ribonucleoprotein complex | 2.72e-05 | 3.93e-01 | 4.485 | 4 | 7 | 112 |
GO:0048024 | regulation of mRNA splicing, via spliceosome | 3.63e-05 | 5.24e-01 | 7.708 | 2 | 2 | 6 |
GO:0000082 | G1/S transition of mitotic cell cycle | 8.31e-05 | 1.00e+00 | 4.073 | 4 | 9 | 149 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.39e-04 | 1.00e+00 | 4.877 | 3 | 6 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.45e-04 | 1.00e+00 | 4.855 | 3 | 6 | 65 |
GO:0005838 | proteasome regulatory particle | 1.59e-04 | 1.00e+00 | 6.708 | 2 | 3 | 12 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.81e-04 | 1.00e+00 | 4.748 | 3 | 8 | 70 |
GO:0030234 | enzyme regulator activity | 1.88e-04 | 1.00e+00 | 6.592 | 2 | 2 | 13 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.97e-04 | 1.00e+00 | 4.708 | 3 | 6 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.13e-04 | 1.00e+00 | 4.668 | 3 | 8 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 2.22e-04 | 1.00e+00 | 4.649 | 3 | 6 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.59e-04 | 1.00e+00 | 4.574 | 3 | 8 | 79 |
GO:0042176 | regulation of protein catabolic process | 2.88e-04 | 1.00e+00 | 6.293 | 2 | 3 | 16 |
GO:0022624 | proteasome accessory complex | 3.26e-04 | 1.00e+00 | 6.205 | 2 | 4 | 17 |
GO:0045070 | positive regulation of viral genome replication | 3.26e-04 | 1.00e+00 | 6.205 | 2 | 2 | 17 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 4.06e-04 | 1.00e+00 | 4.354 | 3 | 6 | 92 |
GO:0006364 | rRNA processing | 4.32e-04 | 1.00e+00 | 4.323 | 3 | 7 | 94 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 5.51e-04 | 1.00e+00 | 5.833 | 2 | 3 | 22 |
GO:0005844 | polysome | 6.03e-04 | 1.00e+00 | 5.769 | 2 | 2 | 23 |
GO:0000209 | protein polyubiquitination | 7.98e-04 | 1.00e+00 | 4.020 | 3 | 7 | 116 |
GO:0045071 | negative regulation of viral genome replication | 1.32e-03 | 1.00e+00 | 5.205 | 2 | 2 | 34 |
GO:0033176 | proton-transporting V-type ATPase complex | 1.59e-03 | 1.00e+00 | 9.293 | 1 | 1 | 1 |
GO:0021691 | cerebellar Purkinje cell layer maturation | 1.59e-03 | 1.00e+00 | 9.293 | 1 | 1 | 1 |
GO:0022605 | oogenesis stage | 1.59e-03 | 1.00e+00 | 9.293 | 1 | 1 | 1 |
GO:0035063 | nuclear speck organization | 1.59e-03 | 1.00e+00 | 9.293 | 1 | 1 | 1 |
GO:0005198 | structural molecule activity | 1.68e-03 | 1.00e+00 | 3.649 | 3 | 6 | 150 |
GO:0042981 | regulation of apoptotic process | 1.68e-03 | 1.00e+00 | 3.649 | 3 | 7 | 150 |
GO:0006521 | regulation of cellular amino acid metabolic process | 2.84e-03 | 1.00e+00 | 4.649 | 2 | 4 | 50 |
GO:0004103 | choline kinase activity | 3.19e-03 | 1.00e+00 | 8.293 | 1 | 1 | 2 |
GO:0016197 | endosomal transport | 3.68e-03 | 1.00e+00 | 4.460 | 2 | 3 | 57 |
GO:0000502 | proteasome complex | 3.81e-03 | 1.00e+00 | 4.435 | 2 | 4 | 58 |
GO:0043066 | negative regulation of apoptotic process | 4.18e-03 | 1.00e+00 | 2.565 | 4 | 13 | 424 |
GO:0009404 | toxin metabolic process | 4.78e-03 | 1.00e+00 | 7.708 | 1 | 1 | 3 |
GO:0035092 | sperm chromatin condensation | 4.78e-03 | 1.00e+00 | 7.708 | 1 | 1 | 3 |
GO:0003729 | mRNA binding | 5.81e-03 | 1.00e+00 | 4.123 | 2 | 2 | 72 |
GO:0004305 | ethanolamine kinase activity | 6.36e-03 | 1.00e+00 | 7.293 | 1 | 1 | 4 |
GO:0005737 | cytoplasm | 6.76e-03 | 1.00e+00 | 0.998 | 12 | 43 | 3767 |
GO:0031584 | activation of phospholipase D activity | 7.95e-03 | 1.00e+00 | 6.971 | 1 | 1 | 5 |
GO:0050684 | regulation of mRNA processing | 7.95e-03 | 1.00e+00 | 6.971 | 1 | 1 | 5 |
GO:1902188 | positive regulation of viral release from host cell | 7.95e-03 | 1.00e+00 | 6.971 | 1 | 1 | 5 |
GO:0061512 | protein localization to cilium | 9.53e-03 | 1.00e+00 | 6.708 | 1 | 1 | 6 |
GO:0002309 | T cell proliferation involved in immune response | 9.53e-03 | 1.00e+00 | 6.708 | 1 | 1 | 6 |
GO:0045182 | translation regulator activity | 9.53e-03 | 1.00e+00 | 6.708 | 1 | 2 | 6 |
GO:0006924 | activation-induced cell death of T cells | 9.53e-03 | 1.00e+00 | 6.708 | 1 | 1 | 6 |
GO:0050792 | regulation of viral process | 9.53e-03 | 1.00e+00 | 6.708 | 1 | 1 | 6 |
GO:0030157 | pancreatic juice secretion | 1.11e-02 | 1.00e+00 | 6.485 | 1 | 1 | 7 |
GO:0006657 | CDP-choline pathway | 1.11e-02 | 1.00e+00 | 6.485 | 1 | 1 | 7 |
GO:0000028 | ribosomal small subunit assembly | 1.11e-02 | 1.00e+00 | 6.485 | 1 | 3 | 7 |
GO:0034101 | erythrocyte homeostasis | 1.11e-02 | 1.00e+00 | 6.485 | 1 | 1 | 7 |
GO:0048193 | Golgi vesicle transport | 1.11e-02 | 1.00e+00 | 6.485 | 1 | 1 | 7 |
GO:0034067 | protein localization to Golgi apparatus | 1.11e-02 | 1.00e+00 | 6.485 | 1 | 1 | 7 |
GO:0005730 | nucleolus | 1.15e-02 | 1.00e+00 | 1.420 | 7 | 24 | 1641 |
GO:0039702 | viral budding via host ESCRT complex | 1.27e-02 | 1.00e+00 | 6.293 | 1 | 1 | 8 |
GO:0005798 | Golgi-associated vesicle | 1.58e-02 | 1.00e+00 | 5.971 | 1 | 1 | 10 |
GO:0006646 | phosphatidylethanolamine biosynthetic process | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 12 |
GO:1903543 | positive regulation of exosomal secretion | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 12 |
GO:0019082 | viral protein processing | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 2 | 12 |
GO:0031929 | TOR signaling | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 13 |
GO:0032479 | regulation of type I interferon production | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 2 | 13 |
GO:0008286 | insulin receptor signaling pathway | 2.13e-02 | 1.00e+00 | 3.143 | 2 | 3 | 142 |
GO:0008284 | positive regulation of cell proliferation | 2.20e-02 | 1.00e+00 | 2.300 | 3 | 7 | 382 |
GO:0030131 | clathrin adaptor complex | 2.21e-02 | 1.00e+00 | 5.485 | 1 | 2 | 14 |
GO:0000278 | mitotic cell cycle | 2.34e-02 | 1.00e+00 | 2.266 | 3 | 11 | 391 |
GO:0031369 | translation initiation factor binding | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 15 |
GO:0048821 | erythrocyte development | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 15 |
GO:0075733 | intracellular transport of virus | 2.68e-02 | 1.00e+00 | 5.205 | 1 | 3 | 17 |
GO:0019068 | virion assembly | 2.68e-02 | 1.00e+00 | 5.205 | 1 | 2 | 17 |
GO:0000287 | magnesium ion binding | 2.78e-02 | 1.00e+00 | 2.935 | 2 | 2 | 164 |
GO:0071889 | 14-3-3 protein binding | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 1 | 18 |
GO:0007369 | gastrulation | 2.99e-02 | 1.00e+00 | 5.045 | 1 | 1 | 19 |
GO:0034641 | cellular nitrogen compound metabolic process | 3.00e-02 | 1.00e+00 | 2.875 | 2 | 4 | 171 |
GO:0043473 | pigmentation | 3.14e-02 | 1.00e+00 | 4.971 | 1 | 1 | 20 |
GO:0019904 | protein domain specific binding | 3.27e-02 | 1.00e+00 | 2.809 | 2 | 3 | 179 |
GO:0000245 | spliceosomal complex assembly | 3.30e-02 | 1.00e+00 | 4.900 | 1 | 1 | 21 |
GO:0007220 | Notch receptor processing | 3.45e-02 | 1.00e+00 | 4.833 | 1 | 2 | 22 |
GO:0045787 | positive regulation of cell cycle | 3.45e-02 | 1.00e+00 | 4.833 | 1 | 2 | 22 |
GO:0006656 | phosphatidylcholine biosynthetic process | 3.45e-02 | 1.00e+00 | 4.833 | 1 | 1 | 22 |
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway | 3.91e-02 | 1.00e+00 | 4.649 | 1 | 2 | 25 |
GO:0005978 | glycogen biosynthetic process | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 2 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 2 | 26 |
GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 1 | 26 |
GO:0045184 | establishment of protein localization | 4.22e-02 | 1.00e+00 | 4.538 | 1 | 2 | 27 |
GO:0015992 | proton transport | 4.53e-02 | 1.00e+00 | 4.435 | 1 | 1 | 29 |
GO:0033572 | transferrin transport | 4.68e-02 | 1.00e+00 | 4.386 | 1 | 1 | 30 |
GO:0001890 | placenta development | 4.83e-02 | 1.00e+00 | 4.338 | 1 | 1 | 31 |
GO:0007093 | mitotic cell cycle checkpoint | 4.83e-02 | 1.00e+00 | 4.338 | 1 | 1 | 31 |
GO:0051701 | interaction with host | 4.98e-02 | 1.00e+00 | 4.293 | 1 | 1 | 32 |
GO:0032480 | negative regulation of type I interferon production | 4.98e-02 | 1.00e+00 | 4.293 | 1 | 2 | 32 |
GO:0008380 | RNA splicing | 5.06e-02 | 1.00e+00 | 2.460 | 2 | 3 | 228 |
GO:0033077 | T cell differentiation in thymus | 5.14e-02 | 1.00e+00 | 4.248 | 1 | 1 | 33 |
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 5.59e-02 | 1.00e+00 | 4.123 | 1 | 3 | 36 |
GO:0090382 | phagosome maturation | 5.59e-02 | 1.00e+00 | 4.123 | 1 | 1 | 36 |
GO:0006915 | apoptotic process | 5.67e-02 | 1.00e+00 | 1.761 | 3 | 9 | 555 |
GO:0008047 | enzyme activator activity | 6.04e-02 | 1.00e+00 | 4.007 | 1 | 1 | 39 |
GO:0042147 | retrograde transport, endosome to Golgi | 6.34e-02 | 1.00e+00 | 3.935 | 1 | 1 | 41 |
GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 6.34e-02 | 1.00e+00 | 3.935 | 1 | 3 | 41 |
GO:0035872 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | 6.64e-02 | 1.00e+00 | 3.866 | 1 | 2 | 43 |
GO:0045087 | innate immune response | 6.73e-02 | 1.00e+00 | 1.658 | 3 | 8 | 596 |
GO:0043065 | positive regulation of apoptotic process | 6.74e-02 | 1.00e+00 | 2.226 | 2 | 6 | 268 |
GO:0045727 | positive regulation of translation | 6.79e-02 | 1.00e+00 | 3.833 | 1 | 1 | 44 |
GO:0008344 | adult locomotory behavior | 6.79e-02 | 1.00e+00 | 3.833 | 1 | 1 | 44 |
GO:0043525 | positive regulation of neuron apoptotic process | 7.09e-02 | 1.00e+00 | 3.769 | 1 | 2 | 46 |
GO:0044297 | cell body | 7.09e-02 | 1.00e+00 | 3.769 | 1 | 1 | 46 |
GO:0005794 | Golgi apparatus | 7.12e-02 | 1.00e+00 | 1.625 | 3 | 9 | 610 |
GO:0007030 | Golgi organization | 7.53e-02 | 1.00e+00 | 3.678 | 1 | 2 | 49 |
GO:0007254 | JNK cascade | 7.53e-02 | 1.00e+00 | 3.678 | 1 | 3 | 49 |
GO:0006879 | cellular iron ion homeostasis | 7.83e-02 | 1.00e+00 | 3.620 | 1 | 1 | 51 |
GO:0030666 | endocytic vesicle membrane | 8.12e-02 | 1.00e+00 | 3.565 | 1 | 2 | 53 |
GO:0051403 | stress-activated MAPK cascade | 8.27e-02 | 1.00e+00 | 3.538 | 1 | 3 | 54 |
GO:0035556 | intracellular signal transduction | 8.34e-02 | 1.00e+00 | 2.049 | 2 | 4 | 303 |
GO:0004674 | protein serine/threonine kinase activity | 8.57e-02 | 1.00e+00 | 2.026 | 2 | 5 | 308 |
GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 1 | 56 |
GO:0043231 | intracellular membrane-bounded organelle | 9.05e-02 | 1.00e+00 | 1.980 | 2 | 5 | 318 |
GO:0032481 | positive regulation of type I interferon production | 9.29e-02 | 1.00e+00 | 3.362 | 1 | 3 | 61 |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 9.29e-02 | 1.00e+00 | 3.362 | 1 | 2 | 61 |
GO:0007059 | chromosome segregation | 9.44e-02 | 1.00e+00 | 3.338 | 1 | 2 | 62 |
GO:0006417 | regulation of translation | 9.44e-02 | 1.00e+00 | 3.338 | 1 | 2 | 62 |
GO:0034146 | toll-like receptor 5 signaling pathway | 9.87e-02 | 1.00e+00 | 3.270 | 1 | 4 | 65 |
GO:0034166 | toll-like receptor 10 signaling pathway | 9.87e-02 | 1.00e+00 | 3.270 | 1 | 4 | 65 |
GO:0046474 | glycerophospholipid biosynthetic process | 1.06e-01 | 1.00e+00 | 3.163 | 1 | 2 | 70 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 1.07e-01 | 1.00e+00 | 3.143 | 1 | 4 | 71 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 1.07e-01 | 1.00e+00 | 3.143 | 1 | 4 | 71 |
GO:0034162 | toll-like receptor 9 signaling pathway | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 4 | 72 |
GO:0034134 | toll-like receptor 2 signaling pathway | 1.10e-01 | 1.00e+00 | 3.103 | 1 | 4 | 73 |
GO:0000139 | Golgi membrane | 1.12e-01 | 1.00e+00 | 1.797 | 2 | 6 | 361 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 1.15e-01 | 1.00e+00 | 3.045 | 1 | 4 | 76 |
GO:0031902 | late endosome membrane | 1.16e-01 | 1.00e+00 | 3.026 | 1 | 2 | 77 |
GO:0005929 | cilium | 1.16e-01 | 1.00e+00 | 3.026 | 1 | 1 | 77 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 1.17e-01 | 1.00e+00 | 3.007 | 1 | 4 | 78 |
GO:0005179 | hormone activity | 1.19e-01 | 1.00e+00 | 2.989 | 1 | 1 | 79 |
GO:0034138 | toll-like receptor 3 signaling pathway | 1.19e-01 | 1.00e+00 | 2.989 | 1 | 4 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 1.20e-01 | 1.00e+00 | 2.971 | 1 | 4 | 80 |
GO:0044281 | small molecule metabolic process | 1.22e-01 | 1.00e+00 | 1.051 | 4 | 15 | 1211 |
GO:0050852 | T cell receptor signaling pathway | 1.27e-01 | 1.00e+00 | 2.883 | 1 | 2 | 85 |
GO:0042384 | cilium assembly | 1.29e-01 | 1.00e+00 | 2.866 | 1 | 1 | 86 |
GO:0042593 | glucose homeostasis | 1.30e-01 | 1.00e+00 | 2.850 | 1 | 1 | 87 |
GO:0016310 | phosphorylation | 1.34e-01 | 1.00e+00 | 2.801 | 1 | 1 | 90 |
GO:0000187 | activation of MAPK activity | 1.34e-01 | 1.00e+00 | 2.801 | 1 | 2 | 90 |
GO:0016363 | nuclear matrix | 1.36e-01 | 1.00e+00 | 2.785 | 1 | 2 | 91 |
GO:0001649 | osteoblast differentiation | 1.37e-01 | 1.00e+00 | 2.769 | 1 | 3 | 92 |
GO:0071456 | cellular response to hypoxia | 1.37e-01 | 1.00e+00 | 2.769 | 1 | 3 | 92 |
GO:0034142 | toll-like receptor 4 signaling pathway | 1.42e-01 | 1.00e+00 | 2.708 | 1 | 4 | 96 |
GO:0055085 | transmembrane transport | 1.52e-01 | 1.00e+00 | 1.528 | 2 | 3 | 435 |
GO:0002224 | toll-like receptor signaling pathway | 1.60e-01 | 1.00e+00 | 2.524 | 1 | 4 | 109 |
GO:0005802 | trans-Golgi network | 1.62e-01 | 1.00e+00 | 2.511 | 1 | 3 | 110 |
GO:0097190 | apoptotic signaling pathway | 1.66e-01 | 1.00e+00 | 2.472 | 1 | 3 | 113 |
GO:0006468 | protein phosphorylation | 1.66e-01 | 1.00e+00 | 1.447 | 2 | 6 | 460 |
GO:0006006 | glucose metabolic process | 1.72e-01 | 1.00e+00 | 2.410 | 1 | 3 | 118 |
GO:0007219 | Notch signaling pathway | 1.75e-01 | 1.00e+00 | 2.386 | 1 | 3 | 120 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1.80e-01 | 1.00e+00 | 2.338 | 1 | 3 | 124 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.86e-01 | 1.00e+00 | 2.293 | 1 | 3 | 128 |
GO:0006644 | phospholipid metabolic process | 1.87e-01 | 1.00e+00 | 2.281 | 1 | 3 | 129 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.96e-01 | 1.00e+00 | 2.205 | 1 | 5 | 136 |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 2.08e-01 | 1.00e+00 | 2.113 | 1 | 3 | 145 |
GO:0010628 | positive regulation of gene expression | 2.09e-01 | 1.00e+00 | 2.103 | 1 | 4 | 146 |
GO:0034220 | ion transmembrane transport | 2.13e-01 | 1.00e+00 | 2.073 | 1 | 2 | 149 |
GO:0010008 | endosome membrane | 2.15e-01 | 1.00e+00 | 2.054 | 1 | 5 | 151 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 2.21e-01 | 1.00e+00 | 2.007 | 1 | 3 | 156 |
GO:0005783 | endoplasmic reticulum | 2.22e-01 | 1.00e+00 | 1.174 | 2 | 3 | 556 |
GO:0006397 | mRNA processing | 2.26e-01 | 1.00e+00 | 1.971 | 1 | 1 | 160 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 2.36e-01 | 1.00e+00 | 1.900 | 1 | 3 | 168 |
GO:0005654 | nucleoplasm | 2.46e-01 | 1.00e+00 | 0.798 | 3 | 15 | 1082 |
GO:0004672 | protein kinase activity | 2.47e-01 | 1.00e+00 | 1.825 | 1 | 4 | 177 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 2.56e-01 | 1.00e+00 | 1.769 | 1 | 3 | 184 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 2.62e-01 | 1.00e+00 | 1.730 | 1 | 4 | 189 |
GO:0001525 | angiogenesis | 2.64e-01 | 1.00e+00 | 1.715 | 1 | 3 | 191 |
GO:0003924 | GTPase activity | 2.71e-01 | 1.00e+00 | 1.670 | 1 | 7 | 197 |
GO:0005765 | lysosomal membrane | 2.78e-01 | 1.00e+00 | 1.627 | 1 | 2 | 203 |
GO:0006184 | GTP catabolic process | 2.91e-01 | 1.00e+00 | 1.551 | 1 | 7 | 214 |
GO:0019221 | cytokine-mediated signaling pathway | 2.99e-01 | 1.00e+00 | 1.505 | 1 | 2 | 221 |
GO:0007067 | mitotic nuclear division | 3.06e-01 | 1.00e+00 | 1.466 | 1 | 5 | 227 |
GO:0030425 | dendrite | 3.09e-01 | 1.00e+00 | 1.447 | 1 | 2 | 230 |
GO:0005975 | carbohydrate metabolic process | 3.35e-01 | 1.00e+00 | 1.310 | 1 | 3 | 253 |
GO:0000166 | nucleotide binding | 3.41e-01 | 1.00e+00 | 1.276 | 1 | 2 | 259 |
GO:0005524 | ATP binding | 3.43e-01 | 1.00e+00 | 0.535 | 3 | 15 | 1298 |
GO:0006281 | DNA repair | 3.43e-01 | 1.00e+00 | 1.265 | 1 | 4 | 261 |
GO:0005515 | protein binding | 3.49e-01 | 1.00e+00 | 0.195 | 11 | 62 | 6024 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 3.52e-01 | 1.00e+00 | 1.221 | 1 | 4 | 269 |
GO:0007264 | small GTPase mediated signal transduction | 3.62e-01 | 1.00e+00 | 1.168 | 1 | 7 | 279 |
GO:0030154 | cell differentiation | 3.85e-01 | 1.00e+00 | 1.059 | 1 | 2 | 301 |
GO:0005525 | GTP binding | 3.94e-01 | 1.00e+00 | 1.016 | 1 | 7 | 310 |
GO:0007275 | multicellular organismal development | 3.99e-01 | 1.00e+00 | 0.989 | 1 | 1 | 316 |
GO:0019901 | protein kinase binding | 4.00e-01 | 1.00e+00 | 0.984 | 1 | 6 | 317 |
GO:0005813 | centrosome | 4.09e-01 | 1.00e+00 | 0.944 | 1 | 5 | 326 |
GO:0015031 | protein transport | 4.23e-01 | 1.00e+00 | 0.879 | 1 | 8 | 341 |
GO:0003723 | RNA binding | 4.24e-01 | 1.00e+00 | 0.875 | 1 | 8 | 342 |
GO:0005634 | nucleus | 4.48e-01 | 1.00e+00 | 0.138 | 8 | 43 | 4559 |
GO:0048471 | perinuclear region of cytoplasm | 5.58e-01 | 1.00e+00 | 0.321 | 1 | 7 | 502 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 6.05e-01 | 1.00e+00 | 0.138 | 1 | 7 | 570 |
GO:0046872 | metal ion binding | 6.30e-01 | 1.00e+00 | -0.060 | 2 | 10 | 1307 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 7.26e-01 | 1.00e+00 | -0.331 | 1 | 6 | 789 |
GO:0005615 | extracellular space | 7.94e-01 | 1.00e+00 | -0.610 | 1 | 2 | 957 |
GO:0005886 | plasma membrane | 8.07e-01 | 1.00e+00 | -0.457 | 3 | 20 | 2582 |
GO:0006351 | transcription, DNA-templated | 9.12e-01 | 1.00e+00 | -1.205 | 1 | 6 | 1446 |